Eosinophilic gastroenteritis and asthma are typically treated with systemic corticosteroids in the severe cases but chronic corticosteroid use often leads to serious long-term adverse effects.1 We herein report a unique case where eosinophilic gastroenteritis, esophagitis, and severe asthma refractory to systemic corticosteroids was and is being effectively managed by mepolizumab and omalizumab.
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