SEVERE OSAS CAUSES SYSTEMIC MICROVASCULAR DYSFUNCTION. CLINICAL EVALUATION OF NINETY‐EIGHT OSAS PATIENTS

Abstract

Obstructive sleep apnea syndrome is described as "Sleep disorder characterized by recurrent episodes of upper respiratory tract obstruction (apnea) and decreased blood‐oxygen saturation occurring during sleep".

The assessment of systemic microvascular density and reactivity is important for cardiovascular disease pathophysiology and cardiovascular risk classification.

Cutaneous microcirculation which can be demonstrated via nailfold capillaroscopy is an easily accessible and acceptable non‐invasive method for the assessment of systemic microcirculation.

OSAS was also explained with various physiopathological mechanisms which may cause microvascular dysfunction.

Capillary density and reactivity in patients with severe OSAS (AHI≥30) are the predictors of systemic microvascular dysfunction and they should be considered as the cause of future cardiovascular events.

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