A three-lncRNA signature derived from the Atlas of ncRNA in cancer (TANRIC) database predicts the survival of patients with head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is the most common malignant lesion in the head and neck region, with an estimated incidence rate of approximately 135.1 per 100,000 in China each year [1]. HNSCC is a heterogeneous solid tumour with more aggressive phenotypes and poor clinical outcomes primarily due to local tumour recurrence and regional lymph node and distant metastasis [2]. Therefore, better understanding of the genetic and epigenetic molecular alterations in HNSCC is the key to improving diagnosis, facilitating the development of appropriate treatments and promoting the prognosis of patients with HNSCC.

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