Predictors of extracapsular extension in HPV-associated oropharyngeal cancer treated surgically

The management of oropharyngeal squamous cell carcinoma (OPSCC) has undergone significant transformation over the last 10years with the advent of transoral robotic surgery (TORS) in the setting of the human papilloma virus (HPV) epidemic [1–4]. The incidence of HPV-related OPSCC is dramatically rising with approximately 45–75% of oropharyngeal malignancy being associated with HPV [2,5–8]. Patients with HPV-related OPSCC also tend to be younger and carry an improved prognosis over traditional HPV negative disease [9].

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