REDD1 links stress with IL-1β-mediated familial Mediterranean fever attack through autophagy-driven neutrophil extracellular traps

Stress-induced protein REDD1 is identified as a novel mediator in the pathogenesis of IL-1β-driven inflammation, through regulation of autophagy-mediated release of NETs. This study links environmental stress with inflammation in FMF attack as well as, with other IL-1β-associated autoinflammatory disorders.

http://ift.tt/2mWe4Lk