Incidence of Pneumonia After Videofluoroscopic Swallowing Study and Associated Factors.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 3 ώρες
*Incidence of Pneumonia After Videofluoroscopic Swallowing Study and Associated Factors.* Dysphagia. 2015 Nov 7; Authors: Jo H, Park JG, Min D, Park HW, Kang EK, Lee KJ, Baek S Abstract Pneumonia after videofluoroscopic swallow study (VFSS) is sometimes considered to be caused by aspiration during VFSS; however, to our knowledge, a relationship between these events has not been clearly investigated. The aim of this study was to assess the incidence of VFSS-related pneumonia and related factors. Overall, 696 VFSS cases were retrospectively reviewed. Cases in which blood culture w...περισσότερα »
Incidence of Pneumonia After Videofluoroscopic Swallowing Study and Associated Factors.
*Incidence of Pneumonia After Videofluoroscopic Swallowing Study and Associated Factors.* Dysphagia. 2015 Nov 7; Authors: Jo H, Park JG, Min D, Park HW, Kang EK, Lee KJ, Baek S Abstract Pneumonia after videofluoroscopic swallow study (VFSS) is sometimes considered to be caused by aspiration during VFSS; however, to our knowledge, a relationship between these events has not been clearly investigated. The aim of this study was to assess the incidence of VFSS-related pneumonia and related factors. Overall, 696 VFSS cases were retrospectively reviewed. Cases in which blood culture w...περισσότερα »
The American Board of Radiology Focused Practice Recognition in Brachytherapy (FPRB) Program: Opportunities lost, lessons learned, and future implications.
*The American Board of Radiology Focused Practice Recognition in Brachytherapy (FPRB) Program: Opportunities lost, lessons learned, and future implications.* Pract Radiat Oncol. 2015 Nov-Dec;5(6):427-432 Authors: Wallner PE, Kupelian P, Erickson B, Alektiar KM, Laszakovits D, Henson TM, Wang PC, Steinberg ML Abstract In 2011, the American Board of Medical Specialties approved a pilot project submitted by the American Board of Radiology for a Focused Practice Recognition in Brachytherapy initiative. Developers had anticipated significant interest within the profession and had hop...περισσότερα »
The use of combinations of monoclonal antibodies in clinical oncology.
*The use of combinations of monoclonal antibodies in clinical oncology.* Cancer Treat Rev. 2015 Oct 30; Authors: Henricks LM, Schellens JH, Huitema AD, Beijnen JH Abstract Treatment with monoclonal antibodies is becoming increasingly important in clinical oncology. These antibodies specifically inhibit signaling pathways in tumor growth and/or induce immunological responses against tumor cells. By combining monoclonal antibodies several pathways may be targeted simultaneously, potentially leading to additive or synergistic effects. Theoretically, antibodies are very suitable for ...περισσότερα »
Antioxidant therapy in the elderly with tinnitus.
*Antioxidant therapy in the elderly with tinnitus.* Braz J Otorhinolaryngol. 2015 Oct 17; Authors: Polanski JF, Soares AD, de Mendonça Cruz OL Abstract INTRODUCTION: Several approaches have been tried for the treatment of tinnitus, from cognitive-behavioral therapies and sound enrichment to medication. In this context, antioxidants, widely used in numerous areas of medicine, appear to represent a promising approach for the control of this symptom, which often is poorly controlled. OBJECTIVE: To evaluate the effects of antioxidant therapy for tinnitus in a group of elderly patient... περισσότερα »
Sensors, Vol. 15, Pages 28257-28270: The Mine LocomotiveWireless Network Strategy Based on Successive Interference Cancellation
We consider a wireless network strategy based on successive interference cancellation (SIC) for mine locomotives. We firstly build the original mathematical model for the strategy which is a non-convex model. Then, we examine this model intensively, and figure out that there are certain regulations embedded in it. Based on these findings, we are able to reformulate the model into a new form and design a simple algorithm which can assign each locomotive with a proper transmitting scheme during the whole schedule procedure. Simulation results show that the outcomes obtained through ...περισσότερα »
Comparing diffusion weighted MRI in the detection of post-operative middle ear cholesteatoma in children and adults.
*Comparing diffusion weighted MRI in the detection of post-operative middle ear cholesteatoma in children and adults.* Int J Pediatr Otorhinolaryngol. 2015 Oct 27; Authors: Nash R, Wong PY, Kalan A, Lingam RK, Singh A Abstract INTRODUCTION: There is a limited evidence base for the use of diffusion weighted MRI (DWMRI) in the assessment of post-operative cholesteatoma in children. This is important to address as this technique is particularly relevant in a paediatric setting. METHODS: We searched a prospectively collected database of patients undergoing DWMRI for the assessment of... περισσότερα »
Letter to the Editor regarding "Sinogenic intracranial abscesses".
*Letter to the Editor regarding "Sinogenic intracranial abscesses".* Int J Pediatr Otorhinolaryngol. 2015 Oct 23; Authors: Gelabert-González M, Arán-Echabe E PMID: 26547233 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1L66LE7 via IFTTT
Management of thyroid gland invasion in laryngeal and hypopharyngeal squamous cell carcinoma.
*Management of thyroid gland invasion in laryngeal and hypopharyngeal squamous cell carcinoma.* Eur Arch Otorhinolaryngol. 2015 Nov 7; Authors: Arslanoğlu S, Eren E, Özkul Y, Ciğer E, Kopar A, Önal K, Etit D, Tütüncü GY Abstract The objective of this study was to determine the incidence of thyroid gland invasion in laryngeal and hypopharyngeal squamous cell carcinoma; and the association between clinicopathological parameters and thyroid gland invasion. Medical records of 75 patients with laryngeal and hypopharyngeal squamous cell carcinoma who underwent total laryngectomy with ... περισσότερα »
Molecules, Vol. 20, Pages 20131-20145: Molecular Differentiated Initiator Reactivity in the Synthesis of Poly(caprolactone)-Based Hydrophobic Homopolymer and Amphiphilic Core Corona Star Polymers
Macromolecules that possess three-dimensional, branched molecular structures are of great interest because they exhibit significantly differentiated application performance compared to conventional linear (straight chain) polymers. This paper reports the synthesis of 3- and 4-arm star branched polymers via ring opening polymerisation (ROP) utilising multi-functional hydroxyl initiators and Sn(Oct)2 as precatalyst. The structures produced include mono-functional hydrophobic and multi-functional amphiphilic core corona stars. The characteristics of the synthetic process were shown t... περισσότερα »
Sensors, Vol. 15, Pages 28257-28270: The Mine LocomotiveWireless Network Strategy Based on Successive Interference Cancellation
We consider a wireless network strategy based on successive interference cancellation (SIC) for mine locomotives. We firstly build the original mathematical model for the strategy which is a non-convex model. Then, we examine this model intensively, and figure out that there are certain regulations embedded in it. Based on these findings, we are able to reformulate the model into a new form and design a simple algorithm which can assign each locomotive with a proper transmitting scheme during the whole schedule procedure. Simulation results show that the outcomes obtained through ...περισσότερα »
Pneumobilia with gastric outlet obstruction
Complications of peptic ulcer disease (PUD) like gastric outlet obstruction (GOO) and biliary fistula have become extremely rare with the advent of proton-pump inhibitors.This is a case of PUD presenting with GOO, a cholecystoduodenal fistula discovered incidentally on upper gastrointestinal endoscopy, and the presence of pneumobilia on a contrast-enhanced CT of the abdomen. A gastrojejunostomy with internal pyloric exclusion was performed. Since the patient did not have any signs of biliary tract disease,we decided not to operate on the fistula to prevent injury to the bile duct.... περισσότερα »
Coarctation of the aorta with left pulmonary artery stenosis: a rare association diagnosed with ECG-gated multislice dual-source CT angiography
We report an extremely rare case of coarctation of the aorta with associated left pulmonary artery stenosis. This violates the traditional fetal flow pattern theory. Two-dimensional echocardiography, although being the initial imaging modality for diagnosing coarctation of the aorta, is limited in the demonstration of branch pulmonary arteries. Retrospective ECG-gated multidetector CT angiography is a non-invasive imaging technique for comprehensive assessment of the site, length and severity of the stenosed aortic segment. It is also helpful in differentiation of an interrupted a... περισσότερα »
Spontaneous resolution of a recurrent axillary cystic hygroma following acute infection
We report a case of spontaneous resolution of a recurrent axillary cystic hygroma in a 4-year-old boy. He presented with a 1-year history of a cystic lump in the left axilla, which intermittently changed in size. Ultrasound suggested it was a lipoma, with raised suspicions of vascular malformation. Scans were discussed in a multidisciplinary meeting and provisional diagnosis of lymphocele or slow flow lymphovascular malformation was made. It was surgically excised and histology confirmed the lesion to be a cystic hygroma. However, it recurred within 3 weeks. The patient was booked ... περισσότερα »
[Treatment of non-cirrhotic, non-tumoural portal vein thrombosis].
*[Treatment of non-cirrhotic, non-tumoural portal vein thrombosis].* Gastroenterol Hepatol. 2015 Nov 4; Authors: Llop E, Seijo S Abstract Thrombosis of the splenoportal axis not associated with liver cirrhosis or neoplasms is a rare disease whose prevalence ranges from 0.7 to 3.7 per 100,000 inhabitants. However, this entity is the second most common cause of portal hypertension. Prothrombotic factors are present as an underlying cause in up to 70% of patients and local factors in 10-50%. The coexistence of several etiological factors is frequent. Clinical presentation may be ac... περισσότερα »
Lymphoepithelial carcinoma of the major salivary glands: Predictors of survival in a non-endemic region.
*Lymphoepithelial carcinoma of the major salivary glands: Predictors of survival in a non-endemic region.* Oral Oncol. 2015 Nov 4; Authors: Zhan KY, Nicolli EA, Khaja SF, Day TA Abstract INTRODUCTION: Lymphoepithelial carcinoma (LEC) of the salivary glands is extremely rare worldwide, with studies limited to small case reports and case series from endemic areas (Southern China, Arctic Inuits) and strong association to Epstein Barr Virus (EBV). Studies on non-endemic regions are even more limited given the reality of only sporadic cases in these areas. Using the National Cancer D... περισσότερα »
From HPV-positive towards HPV-driven oropharyngeal squamous cell carcinomas.
*From HPV-positive towards HPV-driven oropharyngeal squamous cell carcinomas.* Cancer Treat Rev. 2015 Oct 31; Authors: Boscolo-Rizzo P, Pawlita M, Holzinger D Abstract The incidence of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC), which is both biologically and clinically distinct from tobacco- and alcohol-related OPSCC, is dramatically increasing. The finding that individuals with HPV-positive local/regionally advanced OPSCC have a significantly better prognosis than their negative counterparts have led to efforts to de-escalate treatment in those patients to avoi...περισσότερα »
Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines.
*Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines.* Oral Oncol. 2015 Nov 4; Authors: Yu V, Rahimy M, Korrapati A, Xuan Y, Zou AE, Krishnan AR, Tsui T, Aguilera JA, Advani S, Crotty Alexander LE, Brumund KT, Wang-Rodriguez J, Ongkeko WM Abstract OBJECTIVES: Evaluate the cytotoxicity and genotoxicity of short- and long-term e-cigarette vapor exposure on a panel of normal epithelial and head and neck squamous cell carcinoma (HNSCC) cell lines. MATERIALS AND METHODS: HaCaT, UMSCC10B, and HN30 were treated with nicotine-containing ... περισσότερα »
Phase II study of proton beam therapy as a nonsurgical approach for mucosal melanoma of the nasal cavity or para-nasal sinuses.
*Phase II study of proton beam therapy as a nonsurgical approach for mucosal melanoma of the nasal cavity or para-nasal sinuses.* Radiother Oncol. 2015 Nov 4; Authors: Zenda S, Akimoto T, Mizumoto M, Hayashi R, Arahira S, Okumura T, Sakurai H Abstract PURPOSE: The aim of this phase II study was to assess the clinical benefit of proton beam therapy for mucosal melanoma of the nasal cavity and para-nasal sinuses. MATERIALS AND METHODS: N0M0 mucosal melanoma of the nasal cavity and para-nasal sinuses were enrolled. Proton therapy was delivered three times per week with a planned to... περισσότερα »
Exacerbation of Dermatomyositis with Recurrence of Rectal Cancer: A Case Report
Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy characterized by cutaneous and muscle manifestations. The association between DM and malignancy has been well recognized for many years. The clinical course of paraneoplastic DM may be affected by malignancies, although the cause and effect relationship between exacerbation of DM and cancer progression is uncertain. Herein, we report a 44-year-old woman who presented with progressive DM associated with rectal cancer. After curative resection of rectal cancer, DM symptoms resolved. Three months after surgery, blood tes... περισσότερα »
TRPM4 non-selective cation channels influence action potentials in rabbit Purkinje fibres
Abstract TRPM4 Ca2+-activated non-selective cation channel activity has been recorded in cardiomyocytes and sinus node cells from mammals. In addition, *TRPM4* gene mutations are associated with human diseases of cardiac conduction, suggesting that TRPM4 plays a role in this aspect of cardiac function. Here we evaluate the TRPM4 contribution to cardiac electrophysiology of Purkinje fibres. Ventricular strips with Purkinje fibres were isolated from rabbit hearts. Intracellular microelectrodes recorded Purkinje fibre activity and the TRPM4 inhibitor 9-phenanthrol was applied to unma... περισσότερα »
Molecules, Vol. 20, Pages 20107-20117: Extremely Randomized Machine Learning Methods for Compound Activity Prediction
Speed, a relatively low requirement for computational resources and high effectiveness of the evaluation of the bioactivity of compounds have caused a rapid growth of interest in the application of machine learning methods to virtual screening tasks. However, due to the growth of the amount of data also in cheminformatics and related fields, the aim of research has shifted not only towards the development of algorithms of high predictive power but also towards the simplification of previously existing methods to obtain results more quickly. In the study, we tested two approaches b... περισσότερα »
IJMS, Vol. 16, Pages 26813-26831: Effect of Human Adipose Tissue Mesenchymal Stem Cells on the Regeneration of Ovine Articular Cartilage
Cell therapy is a promising approach to improve cartilage healing. Adipose tissue is an abundant and readily accessible cell source. Previous studies have demonstrated good cartilage repair results with adipose tissue mesenchymal stem cells in small animal experiments. This study aimed to examine these cells in a large animal model. Thirty knees of adult sheep were randomly allocated to three treatment groups: CELLS (scaffold seeded with human adipose tissue mesenchymal stem cells), SCAFFOLD (scaffold without cells), or EMPTY (untreated lesions). A partial thickness defect was cre... περισσότερα »
IJMS, Vol. 16, Pages 26797-26812: The Function of Autophagy in Neurodegenerative Diseases
Macroautophagy, hereafter referred to as autophagy, is a bulk degradation process performed by lysosomes in which aggregated and altered proteins as well as dysfunctional organelles are decomposed. Autophagy is a basic cellular process that maintains homeostasis and is crucial for postmitotic neurons. Thus, impaired autophagic processes in neurons lead to improper homeostasis and neurodegeneration. Recent studies have suggested that impairments of the autophagic process are associated with several neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntin...περισσότερα »
Management of thyroid gland invasion in laryngeal and hypopharyngeal squamous cell carcinoma.
*Management of thyroid gland invasion in laryngeal and hypopharyngeal squamous cell carcinoma.* Eur Arch Otorhinolaryngol. 2015 Nov 7; Authors: Arslanoğlu S, Eren E, Özkul Y, Ciğer E, Kopar A, Önal K, Etit D, Tütüncü GY Abstract The objective of this study was to determine the incidence of thyroid gland invasion in laryngeal and hypopharyngeal squamous cell carcinoma; and the association between clinicopathological parameters and thyroid gland invasion. Medical records of 75 patients with laryngeal and hypopharyngeal squamous cell carcinoma who underwent total laryngectomy with ... περισσότερα »
Cytological accuracy and radiological staging in patients with thyroid cancer in Glasgow.
*Cytological accuracy and radiological staging in patients with thyroid cancer in Glasgow.* Eur Arch Otorhinolaryngol. 2015 Nov 7; Authors: Montgomery J, Hendry J, Van der Horst C, Hunter MA, MacKenzie K, Hilmi O Abstract To assess the accuracy of initial combined cytological accuracy and radiological staging of patients suspected of having thyroid malignancy with their final histopathology. Retrospective case series in a tertiary referral centre for head and neck malignancy. All patients with malignant thyroid cytology and cytology suspicious for malignancy, between the dates ...περισσότερα »
Exacerbation of Dermatomyositis with Recurrence of Rectal Cancer: A Case Report
Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy characterized by cutaneous and muscle manifestations. The association between DM and malignancy has been well recognized for many years. The clinical course of paraneoplastic DM may be affected by malignancies, although the cause and effect relationship between exacerbation of DM and cancer progression is uncertain. Herein, we report a 44-year-old woman who presented with progressive DM associated with rectal cancer. After curative resection of rectal cancer, DM symptoms resolved. Three months after surgery, blood tes... περισσότερα »
TRPM4 non-selective cation channels influence action potentials in rabbit Purkinje fibres
Abstract TRPM4 Ca2+-activated non-selective cation channel activity has been recorded in cardiomyocytes and sinus node cells from mammals. In addition, *TRPM4* gene mutations are associated with human diseases of cardiac conduction, suggesting that TRPM4 plays a role in this aspect of cardiac function. Here we evaluate the TRPM4 contribution to cardiac electrophysiology of Purkinje fibres. Ventricular strips with Purkinje fibres were isolated from rabbit hearts. Intracellular microelectrodes recorded Purkinje fibre activity and the TRPM4 inhibitor 9-phenanthrol was applied to unma... περισσότερα »
Molecules, Vol. 20, Pages 20107-20117: Extremely Randomized Machine Learning Methods for Compound Activity Prediction
Speed, a relatively low requirement for computational resources and high effectiveness of the evaluation of the bioactivity of compounds have caused a rapid growth of interest in the application of machine learning methods to virtual screening tasks. However, due to the growth of the amount of data also in cheminformatics and related fields, the aim of research has shifted not only towards the development of algorithms of high predictive power but also towards the simplification of previously existing methods to obtain results more quickly. In the study, we tested two approaches b... περισσότερα »
IJMS, Vol. 16, Pages 26813-26831: Effect of Human Adipose Tissue Mesenchymal Stem Cells on the Regeneration of Ovine Articular Cartilage
Cell therapy is a promising approach to improve cartilage healing. Adipose tissue is an abundant and readily accessible cell source. Previous studies have demonstrated good cartilage repair results with adipose tissue mesenchymal stem cells in small animal experiments. This study aimed to examine these cells in a large animal model. Thirty knees of adult sheep were randomly allocated to three treatment groups: CELLS (scaffold seeded with human adipose tissue mesenchymal stem cells), SCAFFOLD (scaffold without cells), or EMPTY (untreated lesions). A partial thickness defect was cre... περισσότερα »
IJMS, Vol. 16, Pages 26797-26812: The Function of Autophagy in Neurodegenerative Diseases
Macroautophagy, hereafter referred to as autophagy, is a bulk degradation process performed by lysosomes in which aggregated and altered proteins as well as dysfunctional organelles are decomposed. Autophagy is a basic cellular process that maintains homeostasis and is crucial for postmitotic neurons. Thus, impaired autophagic processes in neurons lead to improper homeostasis and neurodegeneration. Recent studies have suggested that impairments of the autophagic process are associated with several neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntin...περισσότερα »
IJMS, Vol. 16, Pages 26754-26769: Mobilization of Copper ions by Flavonoids in Human Peripheral Lymphocytes Leads to Oxidative DNA Breakage: A Structure Activity Study
Epidemiological studies have linked dietary consumption of plant polyphenols with lower incidence of various cancers. In particular, flavonoids (present in onion, tomato and other plant sources) induce apoptosis and cytotoxicity in cancer cells. These can therefore be used as lead compounds for the synthesis of novel anticancer drugs with greater bioavailability. In the present study, we examined the chemical basis of cytotoxicity of flavonoids by studying the structure–activity relationship of myricetin (MN), fisetin (FN), quercetin (QN), kaempferol (KL) and galangin (GN). Using ... περισσότερα »
IJMS, Vol. 16, Pages 26786-26796: Global Profiling of Various Metabolites in Platycodon grandiflorum by UPLC-QTOF/MS
In this study, a method of metabolite profiling based on UPLC-QTOF/MS was developed to analyze Platycodon grandiflorum. In the optimal UPLC, various metabolites, including major platycosides, were separated well in 15 min. The metabolite extraction protocols were also optimized by selecting a solvent for use in the study, the ratio of solvent to sample and sonication time. This method was used to profile two different parts of P. grandiflorum, i.e., the roots of P. grandiflorum (PR) and the stems and leaves of P. grandiflorum (PS), in the positive and negative ion modes. As a resu... περισσότερα »
IJMS, Vol. 16, Pages 26770-26785: Numerical Analysis of Hydrodynamic Flow in Microfluidic Biochip for Single-Cell Trapping Application
Single-cell analysis has become the interest of a wide range of biological and biomedical engineering research. It could provide precise information on individual cells, leading to important knowledge regarding human diseases. To perform single-cell analysis, it is crucial to isolate the individual cells before further manipulation is carried out. Recently, microfluidic biochips have been widely used for cell trapping and single cell analysis, such as mechanical and electrical detection. This work focuses on developing a finite element simulation model of single-cell trapping syst... περισσότερα »
Molecules, Vol. 20, Pages 20118-20130: Design and Synthesis of New 2-Aryl-4,5-Dihydro-thiazole Analogues: In Vitro Antibacterial Activities and Preliminary Mechanism of Action
Sixty 2-aryl-4,5-dihydrothiazoles were designed and synthesized in yields ranging from 64% to 89% from cysteine and substituted-benzonitriles via a novel metal- and catalyst-free method. The structures of the title compounds were confirmed mainly by NMR spectral data analysis. Antibacterial activity assays showed that the compounds (S)-2-(2′-hydroxyphenyl)-4-hydroxy-methyl- 4,5-dihydrothiazole (7h) and (R)-2-(2′-hydroxyphenyl)-4-hydroxymethyl-4,5-dihydro-thiazole (7h′) exhibited significant inhibition against Ralstonia solanacearum, Pseudomonas syringae pv. actinidiae, Bacillus su... περισσότερα »
Development and characterization of 33 novel polymorphic microsatellite markers for the brown tree snake Boiga irregularis.
*Development and characterization of 33 novel polymorphic microsatellite markers for the brown tree snake Boiga irregularis.* BMC Res Notes. 2015;8(1):658 Authors: Unger SD, Abernethy EF, Lance SL, Beasley RR, Kimball BA, McAuliffe TW, Jones KL, Rhodes OE Abstract BACKGROUND: Boiga irregularis is a widespread invasive species on Guam and has led to extirpation of most of the island's native avifauna. There are presently no microsatellite markers for this invasive species, hence we developed highly polymorphic microsatellite markers to allow for robust population genetic studies ... περισσότερα »
IJMS, Vol. 16, Pages 26754-26769: Mobilization of Copper ions by Flavonoids in Human Peripheral Lymphocytes Leads to Oxidative DNA Breakage: A Structure Activity Study
Epidemiological studies have linked dietary consumption of plant polyphenols with lower incidence of various cancers. In particular, flavonoids (present in onion, tomato and other plant sources) induce apoptosis and cytotoxicity in cancer cells. These can therefore be used as lead compounds for the synthesis of novel anticancer drugs with greater bioavailability. In the present study, we examined the chemical basis of cytotoxicity of flavonoids by studying the structure–activity relationship of myricetin (MN), fisetin (FN), quercetin (QN), kaempferol (KL) and galangin (GN). Using ... περισσότερα »
IJMS, Vol. 16, Pages 26786-26796: Global Profiling of Various Metabolites in Platycodon grandiflorum by UPLC-QTOF/MS
In this study, a method of metabolite profiling based on UPLC-QTOF/MS was developed to analyze Platycodon grandiflorum. In the optimal UPLC, various metabolites, including major platycosides, were separated well in 15 min. The metabolite extraction protocols were also optimized by selecting a solvent for use in the study, the ratio of solvent to sample and sonication time. This method was used to profile two different parts of P. grandiflorum, i.e., the roots of P. grandiflorum (PR) and the stems and leaves of P. grandiflorum (PS), in the positive and negative ion modes. As a resu... περισσότερα »
IJMS, Vol. 16, Pages 26770-26785: Numerical Analysis of Hydrodynamic Flow in Microfluidic Biochip for Single-Cell Trapping Application
Single-cell analysis has become the interest of a wide range of biological and biomedical engineering research. It could provide precise information on individual cells, leading to important knowledge regarding human diseases. To perform single-cell analysis, it is crucial to isolate the individual cells before further manipulation is carried out. Recently, microfluidic biochips have been widely used for cell trapping and single cell analysis, such as mechanical and electrical detection. This work focuses on developing a finite element simulation model of single-cell trapping syst... περισσότερα »
Molecules, Vol. 20, Pages 20118-20130: Design and Synthesis of New 2-Aryl-4,5-Dihydro-thiazole Analogues: In Vitro Antibacterial Activities and Preliminary Mechanism of Action
Sixty 2-aryl-4,5-dihydrothiazoles were designed and synthesized in yields ranging from 64% to 89% from cysteine and substituted-benzonitriles via a novel metal- and catalyst-free method. The structures of the title compounds were confirmed mainly by NMR spectral data analysis. Antibacterial activity assays showed that the compounds (S)-2-(2′-hydroxyphenyl)-4-hydroxy-methyl- 4,5-dihydrothiazole (7h) and (R)-2-(2′-hydroxyphenyl)-4-hydroxymethyl-4,5-dihydro-thiazole (7h′) exhibited significant inhibition against Ralstonia solanacearum, Pseudomonas syringae pv. actinidiae, Bacillus su... περισσότερα »
Rapid bladder cancer cell detection from clinical urine samples using an ultra-thin silicone membrane
[image: GA?id=C5AN01616A] *Analyst*, 2016, Advance Article *DOI*: 10.1039/C5AN01616A, Paper Jennie H. Appel, Hao Ren, Mandy L. Y. Sin, Joseph C. Liao, Junseok Chae A high-throughput strategy capable of differentiating bladder cancer cells from non-cancerous cells based on their respective cellular traction forces. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/1MGEi92 via IFTTT
Real-time imaging of cancer cell chemotaxis in paper-based scaffolds
[image: GA?id=C5AN01787D] *Analyst*, 2015, Advance Article *DOI*: 10.1039/C5AN01787D, Paper Rachael M. Kenney, Matthew W. Boyce, Andrew S. Truong, C. Robert Bagnell, Matthew R. Lockett An easy to assemble paper-based invasion assay to study chemotaxis of breast cancer cells in gradients of oxygen in real-time. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/1MGEfds via IFTTT
Amine neurotransmitters, inflammation and epithelial sodium transport
Abstract The physiological importance of the renal actions of monoamines (dopamine, norepinephrine and 5-hydroxytryptamine) mainly depends on the sources of the amines in the kidney and on their availability to activate the amine specific receptors. Dopamine and 5-hydroxytryptamine (5-HT) are also relatively abundant in the intestine mucosal cell layer and recent evidence suggest on their physiological relevance in regulating electrolyte transport. The gastrointestinal tract can be an important site for the loss of water and electrolytes, namely accompanying intestinal inflammatio... περισσότερα »
IJERPH, Vol. 12, Pages 14244-14259: Factors Associated with the Competencies of Public Health Workers in Township Hospitals: A Cross-Sectional Survey in Chongqing Municipality, China
Purpose: This study aimed to explore the competencies of public health workers (PHWs) of township hospitals in Chongqing Municipality (China), and determine the related impact factors of the competencies of PHWs; Methods: A cross-sectional research was conducted on 314 PHWs from 27 township hospitals in three districts in Chongqing Municipality (China), from June to August 2014. A self-assessment questionnaire was established on the basis of literature reviews and a competency dictionary. The differences in competencies among the three districts were determined by adopting the chi...περισσότερα »
IJERPH, Vol. 12, Pages 14216-14228: Physiological and Psychological Effects of a Walk in Urban Parks in Fall
In recent times, attention has been focused on the role of urban green spaces in promoting human health and well-being. However, there is a lack of evidence-based research on the physiological effects of walking in urban green areas. This study aimed to clarify the physiological and psychological effects of walking in urban parks during fall. Twenty-three males (mean age 22.3 ± 1.2 years) were instructed to walk predetermined 15-min courses in an urban park and in a nearby city area (control). Heart rate and heart rate variability were measured to assess physiological responses, a... περισσότερα »
IJERPH, Vol. 12, Pages 14260-14274: Perceived Relevance of Educative Information on Public (Skin) Health: Results of a Representative, Population-Based Telephone Survey
Individual skin health attitudes are influenced by various factors, including public education campaigns, mass media, family, and friends. Evidence-based, educative information materials assist communication and decision-making in doctor-patient interactions. The present study aims at assessing the prevailing use of skin health information material and sources and their impact on skin health knowledge, motives to tan, and sun protection. We conducted a questionnaire survey among a representative sample of Austrian residents. Print media and television were perceived as the two mos... περισσότερα »
IJERPH, Vol. 12, Pages 14229-14243: Variation in the Effect of Particulate Matter on Pulmonary Function in Schoolchildren in Western Japan and Its Relation with Interleukin-8
This study aimed to investigate the effects of particulate matter (PM) on pulmonary function in schoolchildren, as well as the relationships of these effects with interleukin-8. Morning peak expiratory flow (PEF) was measured daily in 399 children during April–May 2012, and in 384 of these children during March–May 2013. PEF's association with the daily levels of suspended particulate matter (SPM) and PM < 2.5 mm (PM2.5) was estimated using a linear mixed model. Interleukin-8 promoter activity was assessed in THP-G8 cells stimulated by fallen PM collected at Tottori University Hosp... περισσότερα »
IJERPH, Vol. 12, Pages 14192-14215: Spatially Explicit Landscape-Level Ecological Risks Induced by Land Use and Land Cover Change in a National Ecologically Representative Region in China
Land use and land cover change is driven by multiple influential factors from environmental and social dimensions in a land system. Land use practices of human decision-makers modify the landscape of the land system, possibly leading to landscape fragmentation, biodiversity loss, or environmental pollution—severe environmental or ecological impacts. While landscape-level ecological risk assessment supports the evaluation of these impacts, investigations on how these ecological risks induced by land use practices change over space and time in response to alternative policy interven... περισσότερα »
IJERPH, Vol. 12, Pages 14275-14284: Associations between Carotid Artery Plaque Score, Carotid Hemodynamics and Coronary Heart Disease
Background: The carotid artery plaque score (PS) is an independent predictor of Coronary Heart Disease (CHD). This study aims to evaluate the combination of PS and carotid hemodynamics to predict CHD. Methods: A total of 476 patients who underwent carotid ultrasonography and coronary angiography were divided into two groups depending on the presence of CHD. PS, carotid intima-media thickness, and carotid blood flow were measured. Receiver operating characteristic curve analysis was performed to establish the best prediction model for CHD presence. Results: Age, sex, carotid intima...περισσότερα »
Real-World Assessment of Clinical Outcomes in Patients with Lower-Risk Myelofibrosis Receiving Treatment with Ruxolitinib
Few trial-based assessments of ruxolitinib in patients with lower-risk myelofibrosis (MF) have been conducted, and no studies have made such assessments in a real-world population. We assessed changes in spleen size and constitutional symptoms during ruxolitinib treatment using a retrospective, observational review of anonymized US medical record data of patients diagnosed with IPSS low-risk () or intermediate-1-risk () MF. The majority of patients were male (low risk, 60%; intermediate-1 risk, 69%). Most patients (92% and 77%) were still receiving ruxolitinib at the medical recor... περισσότερα »
Acceptability of provider-initiated HIV testing as an intervention for prevention of mother to child transmission of HIV and associated factors among pregnant women attending at Public Health Facilities in Assosa town, Northwest Ethiopia
Background: Despite more efforts for prevention of mother to child HIV transmission, still there are problems with provider-initiated HIV testing. This study was done to assess the acceptance rate of provider-initiated HIV testing among antenatal care attendants and its associated factors. Methods: Institutions based cross sectional study with a sample size of 398 was conducted from February to March 2014 in two health facilities in Assosa town. Proportional allocation of the sample size of health facilities followed by systematic sampling method was done; data were collected usin... περισσότερα »
Neonatal preintubation sedation: a national survey in Malaysia
Background: There is a shift of practice towards administering sedation in neonates around the world. At the present moment, there is no available data or literature on the practice of sedation before intubation of neonates in Malaysia thus, evaluation of these practice was not possible. This study was conducted to evaluate neonatal preintubation sedation practice and the availability of neonatal preintubation sedation policy in government, university and private Malaysian Neonatal Intensive Care Units (NICUs) in 2007. Methods: All 43 NICUs in Malaysia were identified and approach...περισσότερα »
Impact of human papillomavirus on head and neck squamous cell cancers in Gabon
Abstract Head and neck squamous cell cancers are among the most aggressive. Their incidence and mortality rates are relatively lower in Middle Africa than worldwide, but in Gabon, these rates tend to be 2–3 fold higher than in neighboring countries. The main risk factors are alcohol and tobacco consumption. However, in the last decades, there was cumulated evidence that human papillomaviruses were a significant risk factor, particularly for oropharyngeal squamous cell cancer. In Gabon, as elsewhere in Africa, assessment of these 3 risk factors need to be improved to determine their... περισσότερα »
Eikenella corrodens Sepsis with Cerebrospinal Fluid Pleocytosis in a Very Low Birth Weight Neonate
We report a case of Eikenella corrodens sepsis associated with CSF pleocytosis in a very low birth weight neonate. A 1000-gram male neonate was born at 27-week gestation due to preterm labor. The patient presented with signs and symptoms of sepsis and was treated for suspected meningitis with intravenous ampicillin and gentamicin for 7 days, with cefotaxime added for three weeks. He had a normal brain MRI at discharge and normal development at 6 months of life. To our knowledge, this is the first case of E. corrodens sepsis and associated meningitis in a very low birth weight neon...περισσότερα »
The American Board of Radiology Focused Practice Recognition in Brachytherapy (FPRB) Program: Opportunities lost, lessons learned, and future implications.
*The American Board of Radiology Focused Practice Recognition in Brachytherapy (FPRB) Program: Opportunities lost, lessons learned, and future implications.* Pract Radiat Oncol. 2015 Nov-Dec;5(6):427-432 Authors: Wallner PE, Kupelian P, Erickson B, Alektiar KM, Laszakovits D, Henson TM, Wang PC, Steinberg ML Abstract In 2011, the American Board of Medical Specialties approved a pilot project submitted by the American Board of Radiology for a Focused Practice Recognition in Brachytherapy initiative. Developers had anticipated significant interest within the profession and had hop...περισσότερα »
The use of combinations of monoclonal antibodies in clinical oncology.
*The use of combinations of monoclonal antibodies in clinical oncology.* Cancer Treat Rev. 2015 Oct 30; Authors: Henricks LM, Schellens JH, Huitema AD, Beijnen JH Abstract Treatment with monoclonal antibodies is becoming increasingly important in clinical oncology. These antibodies specifically inhibit signaling pathways in tumor growth and/or induce immunological responses against tumor cells. By combining monoclonal antibodies several pathways may be targeted simultaneously, potentially leading to additive or synergistic effects. Theoretically, antibodies are very suitable for ...περισσότερα »
Rapid bladder cancer cell detection from clinical urine samples using an ultra-thin silicone membrane
[image: GA?id=C5AN01616A] *Analyst*, 2016, Advance Article *DOI*: 10.1039/C5AN01616A, Paper Jennie H. Appel, Hao Ren, Mandy L. Y. Sin, Joseph C. Liao, Junseok Chae A high-throughput strategy capable of differentiating bladder cancer cells from non-cancerous cells based on their respective cellular traction forces. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/1MGEi92 via IFTTT
Real-time imaging of cancer cell chemotaxis in paper-based scaffolds
[image: GA?id=C5AN01787D] *Analyst*, 2015, Advance Article *DOI*: 10.1039/C5AN01787D, Paper Rachael M. Kenney, Matthew W. Boyce, Andrew S. Truong, C. Robert Bagnell, Matthew R. Lockett An easy to assemble paper-based invasion assay to study chemotaxis of breast cancer cells in gradients of oxygen in real-time. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/1MGEfds via IFTTT
Amine neurotransmitters, inflammation and epithelial sodium transport
Abstract The physiological importance of the renal actions of monoamines (dopamine, norepinephrine and 5-hydroxytryptamine) mainly depends on the sources of the amines in the kidney and on their availability to activate the amine specific receptors. Dopamine and 5-hydroxytryptamine (5-HT) are also relatively abundant in the intestine mucosal cell layer and recent evidence suggest on their physiological relevance in regulating electrolyte transport. The gastrointestinal tract can be an important site for the loss of water and electrolytes, namely accompanying intestinal inflammatio... περισσότερα »
IJERPH, Vol. 12, Pages 14244-14259: Factors Associated with the Competencies of Public Health Workers in Township Hospitals: A Cross-Sectional Survey in Chongqing Municipality, China
Purpose: This study aimed to explore the competencies of public health workers (PHWs) of township hospitals in Chongqing Municipality (China), and determine the related impact factors of the competencies of PHWs; Methods: A cross-sectional research was conducted on 314 PHWs from 27 township hospitals in three districts in Chongqing Municipality (China), from June to August 2014. A self-assessment questionnaire was established on the basis of literature reviews and a competency dictionary. The differences in competencies among the three districts were determined by adopting the chi...περισσότερα »
IJERPH, Vol. 12, Pages 14216-14228: Physiological and Psychological Effects of a Walk in Urban Parks in Fall
In recent times, attention has been focused on the role of urban green spaces in promoting human health and well-being. However, there is a lack of evidence-based research on the physiological effects of walking in urban green areas. This study aimed to clarify the physiological and psychological effects of walking in urban parks during fall. Twenty-three males (mean age 22.3 ± 1.2 years) were instructed to walk predetermined 15-min courses in an urban park and in a nearby city area (control). Heart rate and heart rate variability were measured to assess physiological responses, a... περισσότερα »
IJERPH, Vol. 12, Pages 14260-14274: Perceived Relevance of Educative Information on Public (Skin) Health: Results of a Representative, Population-Based Telephone Survey
Individual skin health attitudes are influenced by various factors, including public education campaigns, mass media, family, and friends. Evidence-based, educative information materials assist communication and decision-making in doctor-patient interactions. The present study aims at assessing the prevailing use of skin health information material and sources and their impact on skin health knowledge, motives to tan, and sun protection. We conducted a questionnaire survey among a representative sample of Austrian residents. Print media and television were perceived as the two mos... περισσότερα »
IJERPH, Vol. 12, Pages 14229-14243: Variation in the Effect of Particulate Matter on Pulmonary Function in Schoolchildren in Western Japan and Its Relation with Interleukin-8
This study aimed to investigate the effects of particulate matter (PM) on pulmonary function in schoolchildren, as well as the relationships of these effects with interleukin-8. Morning peak expiratory flow (PEF) was measured daily in 399 children during April–May 2012, and in 384 of these children during March–May 2013. PEF's association with the daily levels of suspended particulate matter (SPM) and PM < 2.5 mm (PM2.5) was estimated using a linear mixed model. Interleukin-8 promoter activity was assessed in THP-G8 cells stimulated by fallen PM collected at Tottori University Hosp... περισσότερα »
IJERPH, Vol. 12, Pages 14192-14215: Spatially Explicit Landscape-Level Ecological Risks Induced by Land Use and Land Cover Change in a National Ecologically Representative Region in China
Land use and land cover change is driven by multiple influential factors from environmental and social dimensions in a land system. Land use practices of human decision-makers modify the landscape of the land system, possibly leading to landscape fragmentation, biodiversity loss, or environmental pollution—severe environmental or ecological impacts. While landscape-level ecological risk assessment supports the evaluation of these impacts, investigations on how these ecological risks induced by land use practices change over space and time in response to alternative policy interven... περισσότερα »
IJERPH, Vol. 12, Pages 14275-14284: Associations between Carotid Artery Plaque Score, Carotid Hemodynamics and Coronary Heart Disease
Background: The carotid artery plaque score (PS) is an independent predictor of Coronary Heart Disease (CHD). This study aims to evaluate the combination of PS and carotid hemodynamics to predict CHD. Methods: A total of 476 patients who underwent carotid ultrasonography and coronary angiography were divided into two groups depending on the presence of CHD. PS, carotid intima-media thickness, and carotid blood flow were measured. Receiver operating characteristic curve analysis was performed to establish the best prediction model for CHD presence. Results: Age, sex, carotid intima...περισσότερα »
Intentional injury against children in sub-Saharan Africa: A tertiary trauma center experience
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1kkdB3U via IFTTT
Characteristics of patients with lower extremity trauma with improved and not improved pain during hospitalization: a pilot study
Pain Management Nursing from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1kFkXi6 via IFTTT
Outcomes of pediatric patients with persistent midline cervical spine tenderness and negative imaging result after trauma
The Journal of Trauma and Acute Care Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1kFkYCC via IFTTT
Developing a Pediatric Burn Treatment Program in a Community Hospital
Pediatric Nursing Journal from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1kkdyVQ via IFTTT
Real-World Assessment of Clinical Outcomes in Patients with Lower-Risk Myelofibrosis Receiving Treatment with Ruxolitinib
Few trial-based assessments of ruxolitinib in patients with lower-risk myelofibrosis (MF) have been conducted, and no studies have made such assessments in a real-world population. We assessed changes in spleen size and constitutional symptoms during ruxolitinib treatment using a retrospective, observational review of anonymized US medical record data of patients diagnosed with IPSS low-risk () or intermediate-1-risk () MF. The majority of patients were male (low risk, 60%; intermediate-1 risk, 69%). Most patients (92% and 77%) were still receiving ruxolitinib at the medical recor... περισσότερα »
Acceptability of provider-initiated HIV testing as an intervention for prevention of mother to child transmission of HIV and associated factors among pregnant women attending at Public Health Facilities in Assosa town, Northwest Ethiopia
Background: Despite more efforts for prevention of mother to child HIV transmission, still there are problems with provider-initiated HIV testing. This study was done to assess the acceptance rate of provider-initiated HIV testing among antenatal care attendants and its associated factors. Methods: Institutions based cross sectional study with a sample size of 398 was conducted from February to March 2014 in two health facilities in Assosa town. Proportional allocation of the sample size of health facilities followed by systematic sampling method was done; data were collected usin... περισσότερα »
Neonatal preintubation sedation: a national survey in Malaysia
Background: There is a shift of practice towards administering sedation in neonates around the world. At the present moment, there is no available data or literature on the practice of sedation before intubation of neonates in Malaysia thus, evaluation of these practice was not possible. This study was conducted to evaluate neonatal preintubation sedation practice and the availability of neonatal preintubation sedation policy in government, university and private Malaysian Neonatal Intensive Care Units (NICUs) in 2007. Methods: All 43 NICUs in Malaysia were identified and approach...περισσότερα »
Expression of Toll-Like Receptors 2 and 4 and Related Cytokines in Patients with Hepatic Cystic and Alveolar Echinococcosis
Several studies have demonstrated the important role of Toll-like receptors in various parasitic infections. This study aims to explore expression of Toll-like receptors (TLRs) and related cytokines in patients with human cystic echinococcosis (CE) and alveolar echinococcosis (AE). 78 subjects including AE group (), CE group (), and healthy controls (HC, ) were enrolled in this study. The mRNA expression levels of TLR2 and TLR4 in blood and hepatic tissue and plasma levels related cytokines were detected by using ELISA. Median levels of TLR2 mRNA in AE and CE groups were significa... περισσότερα »
Constitutive Activation of the Nlrc4 Inflammasome Prevents Hepatic Fibrosis and Promotes Hepatic Regeneration after Partial Hepatectomy
TThe molecular mechanisms responsible for the development of hepatic fibrosis are not fully understood. The Nlrc4 inflammasome detects cytosolic presence of bacterial components, activating inflammatory cytokines to facilitate clearance of pathogens and infected cells. We hypothesized that low-grade constitutive activation of the Nlrc4 inflammasome may lead to induced hepatocyte proliferation and prevent the development of hepatic fibrosis. The gene of Nlrc4 contains two single nucleotide polymorphisms (SNPs), one located within the Nlrc4 promoter and one contained within exon 5. ... περισσότερα »
Ambient temperature and prevalence of obesity: A nationwide population-based study in Korea
PLOS ONE from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB6dN via IFTTT
Assessment of efficacy and safety of EUS-guided biliary drainage: A systematic review
Gastrointestinal Endoscopy from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB6dF via IFTTT
Cirrhotic cardiomyopathy
World Journal of Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc7By via IFTTT
Epidemiology and healthcare resource utilization associated with children with short bowel syndrome in the United States
Journal of Parenteral and Enteral Nutrition from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB6dB via IFTTT
Gastric motor dysfunctions in Parkinson's disease: Current pre-clinical evidence
Parkinsonism & Related Disorders from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc9JL via IFTTT
Second-line treatment of metastatic gastric cancer: Current options and future directions
World Journal of Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB5X5 via IFTTT
Trends in receipt and timing of multimodality therapy in early-stage pancreatic cancer
Journal of Gastrointestinal Surgery from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc9tn via IFTTT
Features and progression of potential celiac disease in adults
Clinical Gastroenterology and Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB5WZ via IFTTT
Vulnerability in elderly patients with gastrointestinal cancer - translation, cultural adaptation and validation of the European Portuguese version of the Vulnerable Elders Survey (VES-13)
BMC Cancer from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc7l8 via IFTTT
Low risk of adenocarcinoma and high-grade dysplasia in patients with non-dysplastic Barrett's esophagus: Results from a cohort from a country with low esophageal adenocarcinoma incidence
United European Gastroenterology Journal from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB3i4 via IFTTT
Abdominal obesity and circulating metabolites: a twin study approach
Metabolism from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc7l3 via IFTTT
Identification of patients at risk for colorectal cancer in primary care: An explorative study with routine healthcare data
European Journal of Gastroenterology & Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB5GF via IFTTT
Zinc intake and risk of Crohn’s disease and ulcerative colitis: a prospective cohort study
International Journal of Epidemiology from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc6xz via IFTTT
Extensive modulation of the fecal metagenome in children with Crohn’s disease during exclusive enteral nutrition
The American Journal of Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB5qf via IFTTT
Hepatitis C virus treatment as prevention in people who inject drugs: Testing the evidence
Current Opinion in Infectious Diseases from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc74K via IFTTT
Hepatitis E infection in patients with severe alcoholic hepatitis: Is there a place for systematic screening
European Journal of Gastroenterology & Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB5q9 via IFTTT
Abdominal obesity and circulating metabolites: a twin study approach
Metabolism from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc7l3 via IFTTT
Ambient temperature and prevalence of obesity: A nationwide population-based study in Korea
PLOS ONE from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB6dN via IFTTT
Assessment of efficacy and safety of EUS-guided biliary drainage: A systematic review
Gastrointestinal Endoscopy from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB6dF via IFTTT
Cirrhotic cardiomyopathy
World Journal of Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc7By via IFTTT
Epidemiology and healthcare resource utilization associated with children with short bowel syndrome in the United States
Journal of Parenteral and Enteral Nutrition from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB6dB via IFTTT
Gastric motor dysfunctions in Parkinson's disease: Current pre-clinical evidence
Parkinsonism & Related Disorders from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc9JL via IFTTT
Second-line treatment of metastatic gastric cancer: Current options and future directions
World Journal of Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB5X5 via IFTTT
Trends in receipt and timing of multimodality therapy in early-stage pancreatic cancer
Journal of Gastrointestinal Surgery from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc9tn via IFTTT
Features and progression of potential celiac disease in adults
Clinical Gastroenterology and Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB5WZ via IFTTT
Vulnerability in elderly patients with gastrointestinal cancer - translation, cultural adaptation and validation of the European Portuguese version of the Vulnerable Elders Survey (VES-13)
BMC Cancer from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc7l8 via IFTTT
Low risk of adenocarcinoma and high-grade dysplasia in patients with non-dysplastic Barrett's esophagus: Results from a cohort from a country with low esophageal adenocarcinoma incidence
United European Gastroenterology Journal from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB3i4 via IFTTT
Identification of patients at risk for colorectal cancer in primary care: An explorative study with routine healthcare data
European Journal of Gastroenterology & Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB5GF via IFTTT
Zinc intake and risk of Crohn’s disease and ulcerative colitis: a prospective cohort study
International Journal of Epidemiology from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc6xz via IFTTT
Extensive modulation of the fecal metagenome in children with Crohn’s disease during exclusive enteral nutrition
The American Journal of Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB5qf via IFTTT
Hepatitis C virus treatment as prevention in people who inject drugs: Testing the evidence
Current Opinion in Infectious Diseases from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc74K via IFTTT
Hepatitis E infection in patients with severe alcoholic hepatitis: Is there a place for systematic screening
European Journal of Gastroenterology & Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB5q9 via IFTTT
First report of an astrovirus type 5 gastroenteritis outbreak in a residential elderly care home identified by sequencing
Journal of Clinical Virology from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc74B via IFTTT
Clinical features of colorectal cancer patients in advanced age: a population-based approach
Internal and Emergency Medicine from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB31q via IFTTT
Targeting host lipid synthesis and metabolism to inhibit dengue and hepatitis C viruses
Antiviral Research from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB59H via IFTTT
Extracorporeal shock wave lithotripsy is a safe and effective treatment for pancreatic stones coexisting with pancreatic pseudocysts
Gastrointestinal Endoscopy from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc6Oc via IFTTT
First report of an astrovirus type 5 gastroenteritis outbreak in a residential elderly care home identified by sequencing
Journal of Clinical Virology from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc74B via IFTTT
Clinical features of colorectal cancer patients in advanced age: a population-based approach
Internal and Emergency Medicine from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB31q via IFTTT
Targeting host lipid synthesis and metabolism to inhibit dengue and hepatitis C viruses
Antiviral Research from #Medicine via ola Kala on Inoreader http://ift.tt/1MGB59H via IFTTT
Extracorporeal shock wave lithotripsy is a safe and effective treatment for pancreatic stones coexisting with pancreatic pseudocysts
Gastrointestinal Endoscopy from #Medicine via ola Kala on Inoreader http://ift.tt/1WIc6Oc via IFTTT
Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum
Exotoxin A is one of the virulence factors of Pseudomonas aeruginosa, a bacterium that can cause infections resulting in adverse health outcomes and increased burden to health care systems. Current methods of diagnosing P. aeruginosa infections are time consuming and can require significant preparation of patient samples. This study utilized a novel variation of the Systematic Evolution of Ligand by Exponential Enrichment, Decoy-SELEX, to identify an Exotoxin A specific single-stranded DNA (ssDNA) molecular recognition element (MRE). Its emphasis is on increasing stringency in dir... περισσότερα »
Descemet’s Stripping Automated Endothelial Keratoplasty versus Descemet’s Membrane Endothelial Keratoplasty in the Fellow Eye for Fuchs Endothelial Dystrophy: A Retrospective Study
Aim. To evaluate visual outcome and endothelial cell density (ECD) after Descemet's Membrane Endothelial Keratoplasty (DMEK) in comparison with Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) in the fellow eye for Fuchs endothelial dystrophy (FED). Design. Single-centre, retrospective case series. Methods. 30 eyes of 30 patients undergoing DMEK, who completed a 1-year follow-up, were compared with 30 fellow eyes which underwent DSAEK for bilateral FED. Main outcome measures studied included Best Corrected Visual Acuity (BCVA) and ECD during a 1-year follow-up perio...περισσότερα »
Dynamic Contrast-Enhanced CT Characterization of Xp11.2 Translocation/TFE3 Gene Fusions versus Papillary Renal Cell Carcinomas
Purpose. To compare the differences of CT characteristics between renal cell carcinomas (RCCs) associated with Xp11.2 translocation/TFE3 gene fusions (Xp11.2 RCCs) and papillary cell renal cell carcinomas (PRCCs). Methods. CT images and clinical records of 64 patients (25 Xp11.2 RCCs, 15 type 1 and 24 type 2 PRCCs) were analyzed and compared retrospectively. Results. Xp11.2 RCC more frequently affected young ( years) women (16/25, 64%) with gross hematuria (12/25, 48%), while PRCC more frequently involved middle-aged ( years) men (28/39, 71.8%) asymptomatically. Xp11.2 RCC tended ... περισσότερα »
Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum
Exotoxin A is one of the virulence factors of Pseudomonas aeruginosa, a bacterium that can cause infections resulting in adverse health outcomes and increased burden to health care systems. Current methods of diagnosing P. aeruginosa infections are time consuming and can require significant preparation of patient samples. This study utilized a novel variation of the Systematic Evolution of Ligand by Exponential Enrichment, Decoy-SELEX, to identify an Exotoxin A specific single-stranded DNA (ssDNA) molecular recognition element (MRE). Its emphasis is on increasing stringency in dir... περισσότερα »
Descemet’s Stripping Automated Endothelial Keratoplasty versus Descemet’s Membrane Endothelial Keratoplasty in the Fellow Eye for Fuchs Endothelial Dystrophy: A Retrospective Study
Aim. To evaluate visual outcome and endothelial cell density (ECD) after Descemet's Membrane Endothelial Keratoplasty (DMEK) in comparison with Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) in the fellow eye for Fuchs endothelial dystrophy (FED). Design. Single-centre, retrospective case series. Methods. 30 eyes of 30 patients undergoing DMEK, who completed a 1-year follow-up, were compared with 30 fellow eyes which underwent DSAEK for bilateral FED. Main outcome measures studied included Best Corrected Visual Acuity (BCVA) and ECD during a 1-year follow-up perio...περισσότερα »
Dynamic Contrast-Enhanced CT Characterization of Xp11.2 Translocation/TFE3 Gene Fusions versus Papillary Renal Cell Carcinomas
Purpose. To compare the differences of CT characteristics between renal cell carcinomas (RCCs) associated with Xp11.2 translocation/TFE3 gene fusions (Xp11.2 RCCs) and papillary cell renal cell carcinomas (PRCCs). Methods. CT images and clinical records of 64 patients (25 Xp11.2 RCCs, 15 type 1 and 24 type 2 PRCCs) were analyzed and compared retrospectively. Results. Xp11.2 RCC more frequently affected young ( years) women (16/25, 64%) with gross hematuria (12/25, 48%), while PRCC more frequently involved middle-aged ( years) men (28/39, 71.8%) asymptomatically. Xp11.2 RCC tended ... περισσότερα »
Effectiveness of workplace interventions in the prevention of upper extremity musculoskeletal disorders and symptoms: an update of the evidence
The burden of disabling musculoskeletal pain and injuries (musculoskeletal disorders, MSDs) arising from work-related causes in many workplaces remains substantial. There is little consensus on the most appropriate interventions for MSDs. Our objective was to update a systematic review of workplace-based interventions for preventing and managing upper extremity MSD (UEMSD). We followed a systematic review process developed by the Institute for Work & Health and an adapted best evidence synthesis. 6 electronic databases were searched (January 2008 until April 2013 inclusive) yieldi...περισσότερα »
Effectiveness of workplace interventions in the prevention of upper extremity musculoskeletal disorders and symptoms: an update of the evidence
The burden of disabling musculoskeletal pain and injuries (musculoskeletal disorders, MSDs) arising from work-related causes in many workplaces remains substantial. There is little consensus on the most appropriate interventions for MSDs. Our objective was to update a systematic review of workplace-based interventions for preventing and managing upper extremity MSD (UEMSD). We followed a systematic review process developed by the Institute for Work & Health and an adapted best evidence synthesis. 6 electronic databases were searched (January 2008 until April 2013 inclusive) yieldi...περισσότερα »
A swallowing coin : A rare cause for chronic epigastric pain in a child
A rare cause for chronic epigastric pain in a child: a coin in gastric tissue for one year στο ScopeMed - RSS 2015-11-08T15-55-51Z *Source:* Gulhane Medical Journal Necati Balamtekin, Sami Eksert, Mustafa Gülgün, Teoman Doğru. Although swallowing coin is very frequently seen in children, it is unusual to remove it without any reason. A 8 years-old boy was referred to us for epigastric pain for one year. He had been examined by physician and a radio-opaque appearence probably due to coin had been shown in the plain film at that time. The patient has not applied to any hospital for preci... περισσότερα »
Determination of sun protection behaviour amoung nursing students
Determination of sun protection behaviour amoung nursing students: 2015-11-08T15-55-51Z *Source:* Gulhane Medical Journal Fatma İlknur Çınar, Fatma Şeyma Çetin, Nurten Kalender, Gülcan Bağcivan. This research is performed to determine the sun protection behaviour of the nursing school students. This descriptive study is performed amoung 278 students of the nursing school who agreed to participate in this research. The data was collected by a form which includes demographic data and the data of sun protection behaviour of the students and by Fitzpatrick Scale which determines skin ... περισσότερα »
Determination of Perceptions and Attitudes of Healthcare Professionals Regarding Health Information on the Internet
Determination of Perceptions and Attitudes of Healthcare Professionals Regarding Health Information on the Internet: 2015-11-08T15-55-51Z *Source:* Gulhane Medical Journal Uzm.Hem. BETÜL TOSUN, Dr. SERPİL ÖZDEMİR, Dr. UĞUR TOSUN, Öğr.Hem. ECENUR ATAÇ, Öğr. Hem. GAMZE CEBECİ. SUMMARY Today individuals can easily access to wide range of information about their health status, disease or treatments by internet. The aim of the study is determination of perceptions and attitudes of healthcare professionals regarding health information on the internet. This descriptive study was conduct...περισσότερα »
Allergic contact dermatitis induced by the anionic surfactant, sodium N-methyl-N-(1-oxododecyl)-beta-alaninate, contained in a daily-use shampoo
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1iNjcOz via IFTTT
Reply to ‘Adjusting for Ethnicity’
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1PxfPIC via IFTTT
Angiotensin receptor antagonist treatment, melanoma incidence and ethnicity
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1iNjcy6 via IFTTT
Transcriptome and Molecular Endocrinology Aspects of Epicardial Adipose Tissue in Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Observational Studies
The objective of this study was to perform a systematic review of published literature on differentially expressed genes (DEGs) in human epicardial adipose tissue (EAT) to identify molecules associated with CVDs. A systematic literature search was conducted in PubMed, SCOPUS, and ISI Web of Science literature databases for papers published before October 2014 that addressed EAT genes and cardiovascular diseases (CVDs). We included original papers that had performed gene expressions in EAT of patients undergoing open-heart surgery. The Reporting Recommendations for Tumor Marker Pro... περισσότερα »
Acute resistance exercise activates rapamycin-sensitive and insensitive mechanisms that control translational activity and capacity in skeletal muscle
Abstract This study aimed to determine i) the effect of acute resistance exercise on mechanisms of ribosome biogenesis, and ii) the impact of mammalian target of rapamycin on ribosome biogenesis, and muscle protein synthesis (MPS) and degradation. Female F344BN rats underwent unilateral electrical stimulation of the sciatic nerve to mimic resistance exercise in the tibialis anterior (TA) muscle. TA muscles were collected at intervals over the 36 h of exercise recovery (REx); separate groups of animals were administered rapamycin pre-exercise (REx+Rapamycin). Resistance exercise led...περισσότερα »
Transcriptome and Molecular Endocrinology Aspects of Epicardial Adipose Tissue in Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Observational Studies
The objective of this study was to perform a systematic review of published literature on differentially expressed genes (DEGs) in human epicardial adipose tissue (EAT) to identify molecules associated with CVDs. A systematic literature search was conducted in PubMed, SCOPUS, and ISI Web of Science literature databases for papers published before October 2014 that addressed EAT genes and cardiovascular diseases (CVDs). We included original papers that had performed gene expressions in EAT of patients undergoing open-heart surgery. The Reporting Recommendations for Tumor Marker Pro... περισσότερα »
Acute resistance exercise activates rapamycin-sensitive and insensitive mechanisms that control translational activity and capacity in skeletal muscle
Abstract This study aimed to determine i) the effect of acute resistance exercise on mechanisms of ribosome biogenesis, and ii) the impact of mammalian target of rapamycin on ribosome biogenesis, and muscle protein synthesis (MPS) and degradation. Female F344BN rats underwent unilateral electrical stimulation of the sciatic nerve to mimic resistance exercise in the tibialis anterior (TA) muscle. TA muscles were collected at intervals over the 36 h of exercise recovery (REx); separate groups of animals were administered rapamycin pre-exercise (REx+Rapamycin). Resistance exercise led...περισσότερα »
Pathways towards Precision Medicine in Cancer Management Using Genomic Information
Publication date: 20 October 2015 *Source:*Journal of Genetics and Genomics, Volume 42, Issue 10 Author(s): Jingwu Xie from Genes via ola Kala on Inoreader http://ift.tt/1leRxIc via IFTTT
Excess risk of urinary tract cancers in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
Summary Background The risk of urinary tract cancers, including kidney and bladder cancers, was increased in transplant recipients receiving thiopurines. Aim To assess the risk of urinary tract cancers in patients with inflammatory bowel disease (IBD) receiving thiopurines in the CESAME observational cohort. Methods Between May 2004 and June 2005, 19 486 patients with IBD, 30.1% of whom were receiving thiopurines, were enrolled. Median follow-up was 35 months (IQR: 29–40). Results Ten and six patients developed respectively kidney and bladder cancer. The incidence rates of ur... περισσότερα »
Magnetic resonance enterography is feasible and reliable in multicenter clinical trials in patients with Crohn's disease, and may help select subjects with active inflammation
Summary Background Reliable tools for patient selection are critical for clinical drug trials. Aim To evaluate a consensus-based, standardised magnetic resonance enterography (MRE) protocol for selecting patients for inclusion in Crohn's disease (CD) multicenter clinical trials. Methods This study recruited 20 patients [Crohn's Disease Activity Index (CDAI) scores: <150 (*n* = 8); 150–220 (*n* = 4); 220–450 (*n* = 8)], to undergo ileocolonoscopy and two MREs (with and without colonic contrast) within a 14-day period. Procedures were scored centrally using, Magnetic Resonance In...περισσότερα »
OtoRhinoLaryngology New Articles,November 9th,2015
Our Clinical Approach to No. 12 Craniofacial Cleft Patient: Case Report *Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 4 δευτερόλεπτα* *Our Clinical Approach to No. 12 Craniofacial Cleft Patient: Case Report: 2015-11-08T15-55-51Z *Source:* Gulhane Medical Journal Andaç Aykan, Serbülent Güzey, Fatih Zor, Doğan Alhan, Serdar Öztürk. Craniofacial clefts are rare congenital malformations of the facial region that can cause any of skin, soft tissue and bone disorders. Having 15 different variations and different clinical presentations in each group make t... περισσότερα »
