Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Τρίτη 5 Οκτωβρίου 2021

Case Reports in Otolaryngology

Frontal Sinus "Hump": An Anatomical Risk Factor for Anterior Skull Base Injury in the Endoscopic Modified Lothrop Approach (Outside-In Frontal Drill-Out), Teppei Takeda, Kazuhiro Omura, Haw Torng, Teru Ebihara, Satoshi Aoki, Kosuke Tochigi, Hiromi Kojima, and Nobuyoshi Otori
Volume 2021 (2021), Article ID 3402496, 5 pages
Unilateral Cysticercosis of the Parotid Gland: Case Report, Diagnosis, and Clinical Management, Zachary Elwell, Shethal Bearelly, Khalid Aboul-Nasr, and Jonathan Lara
Volume 2021 (2021), Article ID 9999441, 4 pages
Traumatic Cochlear Implant Electrode Extrusion: Considerations, Management, and Outcome, Ching Yee Chan, Feifan Wang, Haryani Omar, and Henry Kun Kiaang Tan
Volume 2021 (2021), Article ID 2918859, 4 pages
The Rare Cases of Parotid Gland Arteriovenous Malformations, Manish Gupta, Vijay Shrawan Nijhawan, Cynthia Kaur, Sukhpreet Kaur, and Akanksha Gupta
Volume 2021 (2021), Article ID 6072155, 5 pages
Osteochondroma Arising from the Thyroid Cartilage: A Case Report and Literature Review, Jessa E. Miller, Shaghauyegh S. Azar, and Dinesh K. Chhetri
Volume 2021 (2021), Article ID 8286012, 4 pages
A Rare Case of Posttraumatic Bilateral BPPV Presentation, Sinisa Maslovara, Andro Kosec, Ivana Pajic Matic, and Anamarija Sestak
Volume 2021 (2021), Article ID 8636676, 5 pages
Nasopharyngeal Coil Dislocation of an Embolized Internal Carotid Artery Pseudoaneurysm, Nazli Ay, Ingo Todt, and Holger Sudhoff
Volume 2021 (2021), Article ID 4270441, 4 pages
Presence of Two Separate Hairy Polyps with Meningothelial Elements in a 15-Month-Old Child, Ahmad Saeed A. Alghamdi, Nasser Almutairi, and Ghassan Alokby
Volume 2021 (2021), Article ID 1844244, 5 pages
Case of Amelanotic Malignant Melanoma of the Lingual Base That Was Diagnosed Based on a Biopsy of Late Metastasis to a Lumbar Vertebra after Being Misdiagnosed as HPV-Positive Oropharyngeal Anterior Wall Squamous Cell Carcinoma, Takumi Okuda, Shinsuke Ide, Kei Kajihara, and Tetsuya Tono
Volume 2021 (2021), Article ID 7139280, 6 pages
Survival of Toddler with Aortoesophageal Fistula after Button Battery Ingestion, Hannah Gibbs, Rishabh Sethia, Patrick I. McConnell, Jennifer H. Aldrink, Toshiharu Shinoka, Kent Williams, and Kris R. Jatana
Volume 2021 (2021), Article ID 5557054, 7 pages

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Telephone consultation 11855 int 1193,

Necessity of Intraoperative Level IIA Lymph Node Dissection in Patients with Carotid Body Tumors: A Retrospective Study of 126 Cases

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Background: Carotid body tumors (CBTs) are relatively uncommon neoplasms that rarely have malignant potential. However, malignant CBTs (MCBTs) are still associated with a poor prognosis and the treatment is still challenging clinically. Therefore, we evaluated the necessity of intraoperative level IIA lymph node dissection in patients with CBT. Methods: The clinical characteristics, intraoperative details, and pathological diagnosis of 126 CBT patients who had undergone surgery were retrospectively reviewed. The patients were divided into 2 groups according to whether level IIA lymph node dissection was performed. The prognosis was analyzed using Kaplan-Meier curves and Cox model multivariate survival analysis. Results: Among the 126 patients, 7 patients (10.3%) in the selective lymph node dissection (SLND) group (68 patients) were diagnosed with MCBTs with evidence of lymph node metastasis. Two patients (3.4%) in the lymph node nondissection (LNND) group (58 patients) were diagnosed with MCBTs later after the second operation because they could not be diagnosed as malignant initially because of the lack of lymph node pathology results although the pathology of the primary lesion showed features of malignancy. The SLND group had a significantly higher relapse-free survival rate than the LNND group (94.1% vs. 79.3%, p = 0.021). Patients with a confirmed diagnosis had a better prognosis than those with insufficient evidence of a malignancy due to the lack of lymph node information. Twenty-nin e patients in the SLND group and 26 patients in the LNND group had postoperative nerve injuries, with no significant difference between the groups (p = 0.879). Conclusion: Intraoperative dissection of level IIA lymph nodes around the tumor in CBT patients can help improve the diagnosis and prognosis of MCBTs without causing additional cranial nerve injury.
ORL
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TRPV1 mediates itch‐associated scratching and skin barrier dysfunction in DNFB‐induced atopic dermatitis mice

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Abstract

In chronic pruritic diseases such as atopic dermatitis (AD), pruritus and skin lesions is exacerbated by scratching in clinical and experimental settings. TRPV1 is known to mediate itch and neurogenic inflammation, but the role of TRPV1 in itch-associated scratching in AD is poorly understood. In this study, we examined the efficacy of cutting off nails and TRPV1 antagonist, ruthenium red (RR) in a murine model of AD induced by DNFB and further investigated the underlying mechanism. Nail clipping or RR could markedly ameliorate the general AD-like symptoms as manifested by the reduced clinical severity of dermatitis, IgE and Th2-related cytokine levels, and mast cell degranulation. Moreover, scratching behavior, the levels of pruritogenic mediators, including HIS, TSLP, IL-31 and SP, and skin pH and TEWL were all significantly decreased in nail clipping or RR-treated mice, suggesting a reduction in itch-associated scratching and skin barrier defects. Immunofluorescence staini ng and western blot results revealed that that antipruritic effect of nail clipping or RR in AD may be explained, at least in part, by the suppression of TRPV1 activation. In summary, these data show that TRPV1 mediates itch-associated scratching and subsequent skin barrier defects, suggesting its potential as a therapeutic target in AD.

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Indocyanine green angiography in breast reconstruction surgery: A systematic review of cost-analysis studies

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J Plast Reconstr Aesthet Surg. 2021 Sep 14:S1748-6815(21)00400-9. doi: 10.1016/j.bjps.2021.08.013. Online ahead of print.

NO ABSTRACT

PMID:34607780 | DOI:10.1016/j.bjps.2021.08.013

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A systematic review and meta-analysis of urethral complications and outcomes in transgender men

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J Plast Reconstr Aesthet Surg. 2021 Sep 4:S1748-6815(21)00384-3. doi: 10.1016/j.bjps.2021.08.006. Online ahead of print.

ABSTRACT

BACKGROUND: Urologic problems, such as urethral fistulas and strictures, are among the most frequent complications occurring after phalloplasty. Although many studies have reported successful phalloplasty and urethral reconstruction with reliable outcomes in transgender men, no method has become standardized so far. This study aimed to summarize the results of reports on urological complications and outcomes in transgender men with respect to various types of urethral reconstruction.

METHODS: A comprehensive literature search of PubMed, Scopus, and Google Scholar databases was conducted for studies related to phalloplasty in transsexuals. Data on various phallic urethral techniques, urethral complications, and outcomes were collected and analyzed using the random-effects model.

RESULTS: A total o f 21 studies (1,566 patients) were included: eight studies (1,061 patients) on "tube-in-tube," nine studies (273 patients) on "prelaminated flap," and six studies (221 patients) on "second flap." Compared with the tube-in-tube technique, the prelaminated flap was associated with a significantly higher urethral stricture/stenosis rate; however, there was no difference between the prelaminated flap and the second flap techniques. For all phalloplasty patients, the pool rate of urethral fistula or stenosis is 48.9%, the rate of the ability to void while standing is 91.5%, occurrence rate of tactile or erogenous sensation is 88%, the prosthesis complication rate is 27.9%, and patient-reported satisfactory outcome rate is 90.5%.

CONCLUSION: Urethral reconstruction with a prelaminated flap was associated with a significantly higher urethral stricture rate and increased need of revision surgery compared with that observed using a skin flap. Overall, most patients were able to void wh ile standing and were satisfied with the outcomes.

PMID:34607781 | DOI:10.1016/j.bjps.2021.08.006

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Transcanal endoscopic management of lateral semicircular canal fistula: preliminary experience

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Eur Arch Otorhinolaryngol. 2021 Oct 5. doi: 10.1007/s00405-021-07095-8. Online ahead of print.

ABSTRACT

INTRODUCTION: Labyrinthine fistula is one of the most frequent complications of cholesteatoma (CHO), occurring in about 8% of cases in the literature. In about 90% of cases, it is located at the level of the lateral semicircular canal, and its clinical manifestation includes vertigo, nystagmus and positive Hennebert and Tullio signs. The management of lateral semicircular canal fistula (LSCF) secondary to CHO classically requires a retroauricular access by performing a canal wall-up (CWU) or canal wall-down (CWD) mastoidectomy. However, in case of a CHO confined to the tympanic cavity causing a LSCF on the ampullar arm, a transcanal exclusive endoscopic approach could be considered.

AIMS: The aim of this study is to describe the feasibility of a transcanal exclusive endoscopic approach in the management of a CHO confined to the tympanic cavity causing a LSCF on the ampullar arm.

METHODS: From January 2019 to December 2020, three patients with LSCF secondary to mesotympanic CHO underwent transcanal exclusive endoscopic ear surgery repair at the Department of Otolaryngology-Head and Neck Surgery, University Hospital of Modena, Italy.

RESULTS: This technique was successfully employed to treat LSCF in all three cases and was planned as a two-stage surgery, performing ossiculoplasty after 12-18 months. Functional outcomes were also satisfactory: complete eradication of CHO, hearing preservation and complete resolution of symptoms.

CONCLUSIONS: In case of a CHO confined to the tympanic cavity causing an LSCF on the ampullar arm, a transcanal exclusive endoscopic approach could be considered as a feasible and safe technique.

PMID:34609605 | DOI:10.1007/s00405-021-07095-8

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KTP laser endoscopic cricopharyngeal myotomy and pharyngeal pouch diverticulotomy: how I do it

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Eur Arch Otorhinolaryngol. 2021 Oct 5. doi: 10.1007/s00405-021-07101-z. Online ahead of print.

ABSTRACT

BACKGROUND: Various endoscopic methods of dividing the cricopharyngeus muscle and the common wall of pharyngeal pouches have been described, most commonly the carbon dioxide laser and stapler. The potassium titanyl phosphate (KTP) laser is an alternate endoscopic method of treatment.

METHODS: The KTP laser is used in a similar fashion to the carbon dioxide laser to carefully divide the cricopharyngeus muscle fibres ± the common wall of the pharyngeal pouch, under microscopic visualization.

CONCLUSION: The KTP laser is an alternative and safe technique for these surgeries.

PMID:34609606 | DOI:10.1007/s00405-021-07101-z

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