Evaluation of low doses BPA-induced perturbation of glycemia by toxicogenomics points to a primary role of pancreatic islets and to the mechanism of toxicity
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
*Evaluation of low doses BPA-induced perturbation of glycemia by toxicogenomics points to a primary role of pancreatic islets and to the mechanism of toxicity* Cell Death and Disease 6, e1959 (October 2015). doi:10.1038/cddis.2015.319 Authors: E Carchia, I Porreca, P J Almeida, F D'Angelo, D Cuomo, M Ceccarelli, M De Felice, M Mallardo & C Ambrosino from Cell via ola Kala on Inoreader http://ift.tt/1MvNmUk via IFTTT
Do You Believe in Haunted Mines?
[image: miningghosttown6.jpg] There is an abundance of ghost towns in the United States – many a result of abandoned mines and disappointed miners. The Garnet Ghost Town in Montana was home to hundreds of people between 1895 and 1912. Most came in search of gold and other precious metals that could be found in the mountains; but Read the rest of this article The post Do You Believe in Haunted Mines? appeared first on Accelerating Science. from Biomedical Engineering via ola Kala on Inoreader http://ift.tt/1MWhLWe via IFTTT
Randomized Controlled Noninferiority Trial Comparing Daptomycin to Vancomycin for the Treatment of Complicated Skin and Skin Structure Infections in an Observation Unit
Publication date: Available online 29 October 2015 *Source:*The Journal of Emergency Medicine Author(s): George J. Shaw, Jason M. Meunier, Joseph Korfhagen, Beth Wayne, Kimberly Hart, Christopher J. Lindsell, Gregory Fermann BackgroundIncidence of methicillin-resistant Staphylococcus aureus (MRSA) is increasing in complicated skin and skin structure infection (cSSSI) presenting to emergency departments (EDs). Treatment is heterogeneous and can require inpatient admission to an observation unit (OU). Vancomycin is commonly used in the OU for treatment, but increasing MRSA resistance t... περισσότερα »
Association between Neurofibromatosis Type 1 and Breast Cancer: A Report of Two Cases with a Review of the Literature
Neurofibromatosis type 1 (NF1) is one of the most common genetic diseases in humans and is associated with various benign and malignant tumors, including breast cancer. However, an increased risk of breast cancer in NF1 patients has not been widely recognized or accepted. Here, we report two cases of breast cancer in NF1 patients and review the literature on the association between NF1 and breast cancer. from Cases via ola Kala on Inoreader http://ift.tt/1P7GU4Z via IFTTT
IL6-induced metastasis modulators p-STAT3, MMP-2 and MMP-9 are targets of 3,3′-diindolylmethane in ovarian cancer cells
Abstract Purpose Ovarian cancer is a highly lethal gynecological malignancy for which the overall prognosis has remained poor over the past few decades. Interleukin (IL6) has been found to be a major contributor to the initiation and progression of ovarian cancer. This cytokine exerts its activity through activation of several signaling pathways, in particular the signal transducer and activator of transcription (STAT3) pathway. Here, we aimed at investigating the capacity of a natural dietary compound found in cruciferous vegetables, i.e., 3,3′-diindolylmethane (DIM), to target th... περισσότερα »
Fine-needle aspiration biopsy
Surgeon-performed ultrasound guided fine-needle aspirate biopsy with report of learning curve; a consecutive case-series study by Vinay Fernandes via Journal of Otolaryngology - Head & Neck Surgery Background: Fine-needle aspiration biopsy has become the standard of care for the evaluation of thyroid nodules. More recently, the use of ultrasound guided fine-needle aspiration biopsy (UG-FNAB) has improved adequacy of sampling. Now there has been improved access to UG-FNAB as ultrasound technology has become more accessible. Here we review the adequacy rate and learning curve of a singl... περισσότερα »
World Allergy Organization anaphylaxis guidelines
2015 update of the evidence base: by F. Simons via World Allergy Organization Journal - Latest Articles The World Allergy Organization (WAO) Guidelines for the assessment and management of anaphylaxis provide a unique global perspective on this increasingly common, potentially life-threatening disease. Recommendations made in the original WAO Anaphylaxis Guidelines remain clinically valid and relevant, and are a widely accessed and frequently cited resource. In this 2015 update of the evidence supporting recommendations in the Guidelines, new information based on anaphylaxis publicat...περισσότερα »
Expression of prostaglandin E2 and EP receptors in human papillary thyroid carcinoma
Expression of prostaglandin E2 and EP receptors in human papillary thyroid carcinoma via Tumor Biology AbstractThe objective of the present study is to determine the role of prostaglandin E2 (PGE2) and downstream EP receptors in the development of human papillary thyroid carcinoma (PTC). A total of 90 thyroid specimens excised from patients undergoing total or subtotal thyroidectomy in the Department of General Surgery, the Fifth Affiliated Hospital of Sun Yat-sen University, China, from August 2013 to September 2014, were analyzed. The quantitative reverse transcription–polymerase c...περισσότερα »
The upregulation of miRNA-146a inhibited biological behaviors of ESCC through inhibition of IRS2
The upregulation of miRNA-146a inhibited biological behaviors of ESCC through inhibition of IRS2 via Tumor Biology AbstractIn recent years, microRNAs, also called as miRNAs, play an important role in carcinogenesis, and the dysregulation of miRNAs is closely associated with cancer progression. Till now, little has been known about the role of miRNA-146a in the esophageal squamous cell carcinomas (ESCC). In the present study, we used in vitro assays to investigate the mechanisms of miRNA-146a in ESCC cell lines and 60 ESCC tissues. Here, we found that miRNA-146a expression is downregu... περισσότερα »
ESCC : Endostatin combined with radiotherapy suppresses vasculogenic mimicry formation through inhibition of epithelial–mesenchymal transition
in esophageal cancer via Tumor Biology AbstractThe growth of solid tumors requires angiogenesis to provide oxygen and nutrients and to support cell proliferation. The switch from an avascular to a vascular phenotype is typically related to acceleration of tumor growth. Anti-angiogenic therapy is becoming a very promising way for malignant tumors. Meanwhile, malignant tumor cells themselves were able to develop the formation of cell-lined vessels that contribute to tumor neovascularization and supply the nutrients and oxygen, which is called vasculogenic mimicry (VM). However, the mo...περισσότερα »
College Students With Autism Spectrum Disorder
Assessment Considerations for by Hewitt, Lynne E. via Topics in Language Disorders - Current Issue As more students identified with autism spectrum disorders (ASD) graduate high school and aspire to a college education, the need for intervention and support targeted to their needs has become apparent. Designing effective programs of support rests on comprehensive and appropriate assessment. This article provides a critical review of areas to consider in clinical assessment of language, communication, and related areas by the speech–language pathologist working with adolescents and yo... περισσότερα »
Students with Autism Spectrum Disorders in Postsecondary Education
Implementing a Communication Coaching Program for by Weiss, Amy L.; Rohland, Pamela via Topics in Language Disorders - Current Issue This article describes the operation of a Communication Coaching Program, which was designed to provide supports for students with autism spectrum disorders (ASDs) attending the University of Rhode Island. To succeed in college programs, many students with ASDs need access to specialized programming and personnel who are able to foster their success in both social and academic venues. The Communication Coaching Program has utilized the principles of in... περισσότερα »
Students With Language Impairments
Understanding the Context: Postsecondary Challenges for by Frink, Melissa Daniel; Whitmire, Kathleen A.; Bogdan, Georgiann via Topics in Language Disorders - Current Issue [image: image] A growing number of high school students with disabilities are planning to continue their education in postsecondary schools, including vocational and career schools, 2- and 4-year colleges, and universities (U.S. Department of Education, Office for Civil Rights, 2011). The transition from secondary settings to postsecondary settings presents unique challenges for students with language impairments a...περισσότερα »
Writing Difficulties in College Students With Language Disorders and/or Learning Disabilities
Characteristics, Assessment, and Treatment of by Richards, Stephanie A. via Topics in Language Disorders - Current Issue Many students currently are enrolled in colleges and universities across the country with language disorders and/or learning disabilities (LLD). The majority of these students struggle with writing, creating a need to identify and provide them with writing intervention services. Speech–language pathologists (SLPs) may provide this intervention; however, many report lacking the confidence, training, and experience to assess and treat writing difficulties in this or ... περισσότερα »
Antidepressants increase the risk of breast cancer or recurrence
Assessing the Risks Associated with Antidepressant Use in Plastic Surgery: A Systematic Review by Teo, Isabel; Song, Christopher Tam via Plastic and Reconstructive Surgery - Current Issue [image: image]Background: Antidepressant use has increased dramatically over the past decade. Although there is no question about the benefits of these medications, uncertainty exists with regard to the implications of antidepressant treatment surrounding plastic surgery. This systematic review collates all of the available literature that evaluates the risks of patient antidepressant treatment, in ... περισσότερα »
The Plastic and Reconstructive Surgery iPad Cosmetic Surgery App
Mastering Cosmetic Surgery: Reflections on [image: Collapse Box]Author Information Section of Plastic and Reconstructive Surgery, Yale University School of Medicine, New Haven, Conn. Correspondence to Dr. Patel, The Institute of Reconstructive Plastic Surgery, New York University Medical Center, New York, N.Y. 10016, anup.patel@nyumc.org If people knew how hard I had to work to gain my *mastery*, it would not seem so wonderful at all. —Michelangelo Sir: Aesthetic plastic surgery demands perfection.1 Every move must be precise, every cut must be accurate, and every suture placed must... περισσότερα »
IL6-induced metastasis modulators p-STAT3, MMP-2 and MMP-9 are targets of 3,3′-diindolylmethane in ovarian cancer cells
Abstract Purpose Ovarian cancer is a highly lethal gynecological malignancy for which the overall prognosis has remained poor over the past few decades. Interleukin (IL6) has been found to be a major contributor to the initiation and progression of ovarian cancer. This cytokine exerts its activity through activation of several signaling pathways, in particular the signal transducer and activator of transcription (STAT3) pathway. Here, we aimed at investigating the capacity of a natural dietary compound found in cruciferous vegetables, i.e., 3,3′-diindolylmethane (DIM), to target th... περισσότερα »
Mitteilungen der DGMKG
from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1LE9F6J via IFTTT
Autologous Dermal Fat Graft Modification for Skate Flap Nipple Reconstruction
Publication date: Available online 28 October 2015 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): David E. Kurlander, George Collis, Steven Bernard from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1jTUtty via IFTTT
Face Lift
Face Lift by Wan, Dinah; Small, Kevin H.; Barton, Fritz E. via Plastic and Reconstructive Surgery - Current Issue [image: image]Learning Objectives: After studying this article, the participant should be able to: 1. Identify the essential anatomy of the aging face and its relationship to face-lift surgery. 2. Understand the common operative approaches to the aging face and a historical perspective. 3. Understand and describe the common complications following face lifting and treatment options. Summary: Surgical rejuvenation of the aging face remains one of the most commonly performe... περισσότερα »
Quality Care in the Treatment of Skin Lesions
Plastic & Reconstructive Surgery: November 2015 - Volume 136 - Issue 5 - p 719e–720e doi: 10.1097/PRS.0000000000001667 Viewpoints Quality Care and the Plastic Surgeon’s Role in the Treatment of Skin Lesions Cabbabe, Edmond B. M.D. Free Access Article Outline [image: Collapse Box]Author Information Advanced Plastic Surgery, Inc., 10004 Kennerly Road, 365B, St. Louis, Mo. 63128,ebcsl@aol.com Sir: The Centers for Medicare & Medicaid Services states that the majority of skin cancers can be managed by simple excision or destruction techniques.1 Plastic surgeons have historically provided cos...περισσότερα »
Normal Saline and an Antiseptic Solution for Negative-Pressure Wound Therapy with Instillation
Comparison of Outcomes for by Kim, Paul J.; Attinger, Christopher E.; Oliver, Noah; Garwood, Caitlin; Evans, Karen K.; Steinberg, John S.; Lavery, Larry A. viaPlastic and Reconstructive Surgery - Current Issue [image: image]Background: Negative-pressure wound therapy with instillation is an adjunctive treatment that uses periodic instillation of a solution and negative pressure for a wide diversity of wounds. A variety of solutions have been reported, with topical antiseptics as the most frequently chosen option. The objective of this study was to compare the outcomes of normal sali... περισσότερα »
Is Inferior Turbinate Lateralization Effective?
Plastic & Reconstructive Surgery: November 2015 - Volume 136 - Issue 5 - p 710e–711e doi: 10.1097/PRS.0000000000001687 Viewpoints Moss, William J. M.D.; Lemieux, Aaron J. B.S.; Alexander, Thomas H. M.D. Free Access Article Outline [image: Collapse Box]Author Information Department of Surgery, Division of Otolaryngology–Head and Neck Surgery, University of California, San Diego, San Diego, Calif. Correspondence to Dr. Moss, Department of Otolaryngology–Head and Neck Surgery, University of California, San Diego, 200 West Arbor Drive, San Diego, Calif. 92103,billy.moss85@gmail.com Sir: Usu...περισσότερα »
Noninvasive Monitoring of Immune Rejection in Face Transplant Recipients
Noninvasive Monitoring of Immune Rejection in Face Transplant Recipients by Kueckelhaus, Maximilian; Imanzadeh, Amir; Fischer, Sebastian; Kumamaru, Kanako; Alhefzi, Muayyad; Bueno, Ericka; Wake, Nicole; Gerhard-Herman, Marie D.; Rybicki, Frank J.; Pomahac, Bohdan via Plastic and Reconstructive Surgery - Current Issue Background: Chronic rejection leading to allograft loss remains a significant concern after facial allotransplantation. Chronic rejection may occur without clinical signs or symptoms. The current means of monitoring is histologic analyses of allograft biopsy specimens, wh...περισσότερα »
Fat Grafting in Primary Cleft Lip Repair
Plastic & Reconstructive Surgery: November 2015 - Volume 136 - Issue 5 - p 708e doi: 10.1097/PRS.0000000000001665 Letters Idone, Francesco M.D.; Sisti, Andrea M.D.; Tassinari, Juri M.D.; Nisi, Giuseppe M.D. Free Access Article Outline [image: Collapse Box]Author Information Jalisco Plastic and Reconstructive Institute, University of Guadalajara, Guadalajara, Jalisco, Mexico General and Specialist Surgery Department, Plastic Surgery Division, University of Siena, Siena, Italy Correspondence to Dr. Idone, Jalisco Plastic and Reconstructive Institute, University of Guadalajara, Avenida Fed... περισσότερα »
Gustatory Sweating Syndrome : Intraparotid Location of the Great Auricular Nerve
Intraparotid Location of the Great Auricular Nerve: A New Anatomical Basis for Gustatory Sweating Syndrome by Toure, Gaoussou via Plastic and Reconstructive Surgery - Current Issue [image: image]Background: Gustatory sweating syndrome (also known as Frey syndrome or auriculotemporal nerve syndrome) is thought to result from a lesion of the auriculotemporal nerve. A lesion of this nerve can lead to aberrant regeneration of nerve fibers to the sweat glands and blood vessels. The occurrence of signs outside the region of the auriculotemporal nerve prompted the author to search for anothe...περισσότερα »
Malar Augmentation with Pedicled Buccal Fat Pad in Orthognathic Surgery
: Three-Dimensional Evaluation by Hernández-Alfaro, Federico; Valls-Ontañón, Adaia; Blasco-Palacio, Julia C.; Guijarro-Martínez, Raquel via Plastic and Reconstructive Surgery - Current Issue [image: image] Background: Contemporary orthognathic surgery contemplates three-dimensional facial soft-tissue harmonization as one of the basic pillars in treatment planning. In particular, prominent malar regions are regarded as a sign of beauty and youth by Western societies. The aim of this article was to perform a subjective and objective three-dimensional evaluation of the pedicled buccal f... περισσότερα »
Orbital Dysmorphology in Untreated Children with Crouzon and Apert Syndromes
Plastic & Reconstructive Surgery: November 2015 - Volume 136 - Issue 5 - p 1054–1062 doi: 10.1097/PRS.0000000000001693 Pediatric/Craniofacial: Original Articles Forte, Antonio Jorge M.D.; Steinbacher, Derek M. M.D., D.M.D.; Persing, John A. M.D.; Brooks, Eric D. B.S.; Andrew, Tom W. M.B.Ch.B.; Alonso, Nivaldo M.D., Ph.D. [image: Collapse Box]Abstract Background: Orbital dysmorphology and midface retrusion are the hallmarks of Crouzon and Apert syndromes. The precise nature of this deficiency is not known. Methods: Untreated Crouzon and Apert syndrome patients and age- and sex-matched c... περισσότερα »
Lip Height Symmetry
The Use of an Inferior Pennant Flap during Unilateral Cleft Lip Repair Improves Lip Height Symmetry by Russell, Aaron J.; Patel, Kamlesh B.; Skolnick, Gary B.; Woo, Albert S. via Plastic and Reconstructive Surgery - Current Issue [image: image] Background: To improve the rotation of Cupid’s bow and achieve sufficient vertical lip height, several variations of the Millard rotation-advancement have incorporated a small laterally based triangular flap above the cutaneous roll. This study uses three-dimensional photogrammetry to evaluate the outcomes of unilateral cleft lip repairs perfor... περισσότερα »
A six-site method for the evaluation of periodontal bone loss in cone-beam CT images.
*A six-site method for the evaluation of periodontal bone loss in cone-beam CT images.* Dentomaxillofac Radiol. 2015 Oct 28;:20150265 Authors: Guo YJ, Ge ZP, Ma RH, Hou JX, Li G Abstract OBJECTIVES: Contrast to 2-dimensional planar images, a measuring point is hardly repeatedly determined in a CBCT image when alveolar bone loss is assessed. Thus, the aim of the present study was to propose a six-site measuring method, which is closely related to anatomical structure, for the evaluation of alveolar bone loss in CBCT images. METHODS: 150 measuring points in 11 molars and 14 premola...περισσότερα »
Cervical vertebrae maturation index estimates on cone-beam computed tomography: 3D reconstructions vs. sagittal sections.
*Cervical vertebrae maturation index estimates on cone-beam computed tomography: 3D reconstructions vs. sagittal sections.* Dentomaxillofac Radiol. 2015 Oct 28;:20150162 Authors: Bonfim MA, Costa AL, Fuziy A, Ximenez ME, Cotrim-Ferreira FA, Ferreira-Santos RI Abstract OBJECTIVES: The aim of this study to evaluate the performance of CBCT tridimensional (3D) reconstructions and sagittal sections for estimates of cervical vertebrae maturation index (CVMI). METHODS: The sample consisted of 72 CBCT examinations from patients aged 8-16 years (45 female, 27 male) selected from the archi... περισσότερα »
Direct restoration modalities of fractured central maxillary incisors: A multi-levels validated finite elements analysis with in vivo strain measurements
Publication date: Available online 28 October 2015 *Source:*Dental Materials Author(s): Apicella Davide, Aversa Raffaella, Tatullo Marco, Simeone Michele, Jamaluddin Syed, Marrelli Massimo, Ferrari Marco, Apicella Antonio ObjectiveTo quantify the influence of fracture geometry and restorative materials rigidity on the stress intensity and distribution of restored fractured central maxillary incisors (CMI) with particular investigation of the adhesive interfaces. Ancillary objectives are to present an innovative technology to measure the in vivo strain state of sound maxillary incisor... περισσότερα »
Columellar Strut Graft in Primary Open Approach Rhinoplasty
Revisiting the Role of [image: Collapse Box]Author Information Jalisco Plastic and Reconstructive Institute, University of Guadalajara, Guadalajara, Jalisco, Mexico Plastic Surgery Division, General and Specialist Surgery Department, University of Siena, Siena, Italy Correspondence to Dr. Idone, Jalisco Plastic and Reconstructive Institute, University of Guadalajara, Avenida Federalismo Norte 2022, Guadalajara, Jalisco, México,francescoidone81@hotmail.it Sir: We have read with great interest the article entitled “Revisiting the Role of Columellar Strut Graft in Primary Open Approach... περισσότερα »
Unilateral Cleft Lip and Palate : Permanent Tooth Agenesis and Maxillary Hypoplasia
Permanent Tooth Agenesis and Maxillary Hypoplasia in Patients with Unilateral Cleft Lip and Palate by Antonarakis, Gregory S.; Fisher, David M. via Plastic and Reconstructive Surgery - Current Issue [image: image] Abstract Background: Maxillary growth in patients with clefts is highly variable. The authors’ aim was to investigate whether severity of maxillary hypoplasia is associated with the presence of permanent tooth agenesis in children with complete unilateral cleft lip and palate. Methods: Fifty children with complete unilateral cleft lip and palate were divided into two groups ... περισσότερα »
Mandibular Distraction Osteogenesis in Low-Weight Neonates with Robin Sequence
: Is It Safe? by Tahiri, Youssef; Greathouse, S. Travis; Tholpady, Sunil S.; Havlik, Robert; Sood, Rajiv; Flores, Roberto L. via Plastic and Reconstructive Surgery - Current Issue Background: The aim of this study was to evaluate the efficacy, safety profile, and complications associated with mandibular distraction osteogenesis performed in infants weighing less than 4 kg with Robin sequence. Methods: An 11-year retrospective review of all infants (younger than 6 months) with mandibular distraction osteogenesis–treated Robin sequence was performed. Patients weighing less than 4 kg (e... περισσότερα »
Fame Fortune Family : Shaping a Career in Plastic Surgery
: Balancing the “Three Fs” by Hidalgo, David A. via Plastic and Reconstructive Surgery - Current Issue [image: image]
Financial Conflicts of Interest
: An Association between Funding and Findings in Plastic Surgery Abstract Background: Despite a growing interest in examining the effects of industry funding on research in plastic surgery, no study to date has comprehensively examined the effects of financial conflicts of interest on publication outcomes. The authors investigated the association between financial conflicts of interest and reported study findings in plastic surgery research. Methods: The authors reviewed all entries in *Plastic and Reconstructive Surgery*, *Annals of Plastic Surgery*, and *Journal of Plastic, Recons... περισσότερα »
The Profunda Artery Perforator Flap
: Investigating the Perforasome Using Three-Dimensional Computed Tomographic Angiography by Wong, Corrine; Nagarkar, Purushottam; Teotia, Sumeet; Haddock, Nicholas T. via Plastic and Reconstructive Surgery - Current Issue Background: The profunda artery perforator flap has been emerging as an alternative method of autologous breast reconstruction. This flap uses upper posterior thigh tissue. The profunda artery perforator perforasome is investigated using three-dimensional computed tomographic angiography. Methods: Ten cadaveric thighs were dissected centered over the profunda artery...περισσότερα »
Fibroblast-Specific Deletion of Hypoxia Inducible Factor-1 Critically Impairs Cutaneous Neovascularization and Wound Healing
Fibroblast-Specific Deletion of Hypoxia Inducible Factor-1 Critically Impairs Murine Cutaneous Neovascularization and Wound Healing by Duscher, Dominik; Maan, Zeshaan N.; Whittam, Alexander J.; Sorkin, Michael; Hu, Michael S.; Walmsley, Graham G.; Baker, Hutton; Fischer, Lauren H.; Januszyk, Michael; Wong, Victor W.; Gurtner, Geoffrey C. via Plastic and Reconstructive Surgery - Current Issue [image: image] B Abstract Background: Diabetes and aging are known risk factors for impaired neovascularization in response to ischemic insult, resulting in chronic wounds, and poor outcomes follo... περισσότερα »
Bone Marrow Stromal Cell Sheets in Maintaining Random-Pattern Skin Flaps
Effectiveness of Bone Marrow Stromal Cell Sheets in Maintaining Random-Pattern Skin Flaps in an Experimental Animal Model by Kira, Tsutomu; Omokawa, Shohei; Akahane, Manabu; Shimizu, Takamasa; Nakano, Kenichi; Nakanishi, Yasuaki; Onishi, Tadanobu; Kido, Akira; Inagaki, Yusuke; Tanaka, Yasuhito via Plastic and Reconstructive Surgery - Current Issue [image: image] Abstract Background: Bone marrow stromal cells can be applied therapeutically to enhance angiogenesis; however, the use of bone marrow stromal cell suspensions reduces efficiency because of low-level attachment. The authors h... περισσότερα »
Burn Injury and Trauma on Muscle and Bone Mass and Composition
The Systemic Effect of by Rinkinen, Jacob; Hwang, Charles D.; Agarwal, Shailesh; Oluwatobi, Eboda; Peterson, Jonathan; Loder, Shawn; Brownly, Robert C.; Cummings, Timothy; Cederna, Paul S.; Levi, Benjamin via Plastic and Reconstructive Surgery - Current Issue [image: image]Background: By understanding the global inflammatory effects on distant myopathies, surgeons can better guide the rehabilitative process for burn patients. The authors tested the systemic effect of burn injury on distant injured muscle and native bone using immunohistochemistry and validated a new morphometric ana...περισσότερα »
Fibroproliferative Scarring,Dermal Fibroblasts from the Red Duroc Pig
Dermal Fibroblasts from the Red Duroc Pig Have an Inherently Fibrogenic Phenotype: An In Vitro Model of Fibroproliferative Scarring by Sood, Ravi F.; Muffley, Lara A.; Seaton, Max E.; Ga, Maricar; Sirimahachaiyakul, Pornthep; Hocking, Anne M.; Gibran, Nicole S. viaPlastic and Reconstructive Surgery - Current Issue [image: image] Background: The pathophysiology of hypertrophic scarring is unknown in part because of the lack of a robust animal model. Although the red Duroc pig has emerged as a promising in vivo model, the cellular mechanisms underlying Duroc scarring are unknown, and th...περισσότερα »
The Collagenase of the Bacterium Clostridium histolyticum for the Treatment of Capsular Fibrosis
after Silicone Implants by Fischer, Sebastian; Hirsch, Tobias; Diehm, Yannick; Kiefer, Jurij; Bueno, Ericka M.; Kueckelhaus, Maximilian; Kremer, Thomas; Hirche, Christoph; Kneser, Ulrich; Pomahac, Bohdan via Plastic and Reconstructive Surgery - Current Issue Background: The main part of the fibrotic capsule in capsular contracture is collagen. The collagenase of the bacterium Clostridium histolyticum is U.S. Food and Drug Administration approved for the treatment of Dupuytren contracture and might be capable of dissolving the fibrotic capsule surrounding silicone implants. Methods: ...περισσότερα »
Eyelid Finger Manipulation in the Treatment of Overcorrected Blepharoptosis and Postblepharoplasty Ectropion-Retraction
Reply: Eyelid Finger Manipulation in the Treatment of Overcorrected Blepharoptosis and Postblepharoplasty Ectropion-Retraction by Putterman, Allen M. via Plastic and Reconstructive Surgery - Current Issue [image: image]
Closed Microfracture Technique for Surgical Correction of Inferior Turbinate Hypertrophy in Rhinoplasty
: Safety and Technical Considerations by Rohrich, Rod J.; McKee, Daniel; Malafa, Menyoli via Plastic and Reconstructive Surgery - Current Issue [image: image]Summary: An abundance of surgical procedures are in use for the management of inferior turbinate hypertrophy in rhinoplasty patients. An ideal treatment approach is elusive, given the variability of patient presentation regarding obstructive nasal airway, significant complications associated with techniques that cause mucosal trauma, and the high recurrence rates associated with more conservative techniques. In an effort to impr... περισσότερα »
Sharing and storing digital patient photographs occur daily in plastic surgery
Digital Photograph Security: What Plastic Surgeons Need to Know by Thomas, Virginia A.; Rugeley, Patricia B.; Lau, Frank H. via Plastic and Reconstructive Surgery - Current Issue Background: Sharing and storing digital patient photographs occur daily in plastic surgery. Two major risks associated with the practice, data theft and Health Insurance Portability and Accountability Act (HIPAA) violations, have been dramatically amplified by high-speed data connections and digital camera ubiquity. The authors review what plastic surgeons need to know to mitigate those risks and provide reco... περισσότερα »
Prevention of Capsular Contracture Using Leukotriene Antagonists
Prevention of Capsular Contracture Using Leukotriene Antagonists by Graf, Ruth; Ascenço, Adriana S. K.; Freitas, Renato da S.; Balbinot, Priscilla; Peressutti, Carolina; Costa, Diogo F. B.; dos Santos, Fábio de H. C. R.; Ratti, Marco A. S.; Kulchetscki, Rodrigo M. via Plastic and Reconstructive Surgery - Current Issue [image: image]Background: Capsular contracture is a common occurrence in plastic surgery, with a prevalence varying from 0.5 percent up to 30 percent. Although the standard treatment is capsulectomy, alternative treatments have been studied, such as the use of leukotrien...περισσότερα »
Optimal Augmentation of the Asian Face with Hyaluronic Acid and Calcium Hydroxylapatite Fillers
Consensus Recommendations for by Rho, Nark-Kyoung; Chang, Yao-Yuan; Chao, Yates Yen-Yu; Furuyama, Nobutaka; Huang, Peter Y. C.; Kerscher, Martina; Kim, Hee-Jin; Park, Je-Young; Peng, Hsien Li Peter; Rummaneethorn, Paisal; Rzany, Berthold; Sundaram, Hema; Wong, Chin Ho; Yang, Yuli; Prasetyo, Adri Dwi via Plastic and Reconstructive Surgery - Current Issue [image: image]Background: Although the use of filling agents for soft-tissue augmentation has increased worldwide, most consensus statements do not distinguish between ethnic populations. There are, however, significant differences b... περισσότερα »
Renal function evaluation in patients with thyroid dysfunction
The correct via Latest Results for Journal of Endocrinological Investigation AbstractThyroid dysfunction induces several renal derangements involving all nephron portions. Furthermore, dysthyroidism is a recognized risk factor associated with the development of chronic kidney disease. Current data, in fact, demonstrate that either subclinical or overt thyroid disease is associated with significant changes in creatinine, estimated glomerular filtration rate, measured glomerular filtration rate and Cystatin C. Herein, we systematically reviewed several relevant studies aiming at the i... περισσότερα »
Platelet-Rich Plasma with Basic Fibroblast Growth Factor for Treatment of Wrinkles and Depressed Areas
of the Skin by Kamakura, Tatsuro; Kataoka, Jiro; Maeda, Kazuhiko; Teramachi, Hideaki; Mihara, Hisayuki; Miyata, Kazuhiro; Ooi, Kouichi; Sasaki, Naomi; Kobayashi, Miyuki; Ito, Kouhei via Plastic and Reconstructive Surgery - Current Issue Background: There are several treatments for wrinkles and depressed areas of the face, hands, and body. Hyaluronic acid is effective, but only for 6 months to 1 year. Autologous fat grafting may cause damage during tissue harvest. Methods: In this study, patients were injected with platelet-rich plasma plus basic fibroblast growth factor (bFGF). Plate...περισσότερα »
Aspiration in individuals with amyotrophic lateral sclerosis
Discriminant ability of the Eating Assessment Tool-10 to detect by E. K. Plowman, L. C. Tabor, R. Robison, J. Gaziano, C. Dion, S. A. Watts, T. Vu, C. Gooch via The European Gastrointestinal Motility Society Abstract Background Oropharyngeal dysphagia is prevalent in individuals with amyotrophic lateral sclerosis (ALS) leading to malnutrition, aspiration pneumonia, and death. These factors necessitate early detection of at-risk patients to prolong maintenance of safe oral intake and pulmonary function. This study aimed to evaluate the discriminant ability of the Eating Assessment Tool... περισσότερα »
Effekt der mikrochirurgischen Entfernung von Vestibularisschwannomen auf das Schmeckvermögen
Effekt der mikrochirurgischen Entfernung von Vestibularisschwannomen auf das Schmeckvermögen by Boeßert, P. via Laryngo-Rhino-Otologie Laryngo-Rhino-Otol DOI: 10.1055/s-0035-1559679 Patienten mit Vestibularisschwannom berichten neben den bekannten Kardinalsymptomen auch über Schmeckstörungen. Wenig ist bisher zu diesem Symptom bei dieser Patientengruppe bekannt. Ziel dieser Untersuchung war es, den Einfluss der operativen Therapie auf das Schmeckvermögen mit Hilfe eines standardisierten Schmecktests prospektiv zu untersuchen. Dafür wurde das Schmeckvermögen mit den Schmeckstreifen vor... περισσότερα »
Postoperative Follow-up after Meningioma Resection
Factors Associated with Low Socioeconomic Status Predict Poor by Nayeri, Arash via Journal of Neurological Surgery Part B: Skull Base J Neurol Surg B DOI: 10.1055/s-0035-1566122 Objectives To quantify the rates of loss of follow-up after meningioma resection and to identify any key demographical associations. Design Retrospective cohort. Setting Vanderbilt University Medical Center, 2001–2013. Participants A total of 281 patients surgically treated for an intracranial meningioma at a single institution between 2001 and 2013. Main Outcome Measures Patient clinical follow-up within the ... περισσότερα »
Improved skin flap survival with the use of adipose-derived stem cells
Improved skin flap survival in venous ischemia-reperfusion injury with the use of adipose-derived stem cells by Hyun Ho Han, Young Min Lim, Sang Wook Park, Su Jin Lee, Jong Won Rhie, Jung Ho Lee via Microsurgery Introduction The purpose of this study was to investigate the efficacy of stem cell therapy as an adjuvant treatment for congested skin flap. Method Sprague-Dawley rats (*n* = 21) were randomized into three groups. In group I, the flap was sutured without venous ischemia. In group II, the vein was selectively clamped for 4 hours, and complete medium was administered upon clamp...περισσότερα »
Active thermoregulation on the microcirculation of free flaps
Impact of by Ulf Dornseifer, Andreas Max Fichter, Sarah Von Isenburg, Sofia Stergioula, Ina-Christine Rondak, Milomir Ninkovic viaMicrosurgery Background While it is a known fact that warming increases blood flow in healthy tissue, little is known about the impact of active thermoregulation on the altered microcirculation of free flaps. The objective of the study was to identify the impact of postoperative active thermoregulation on free flap microcirculation. Methods Tissue temperature was assessed in 25 free perforator flaps using an implanted probe. Active thermoregulation was ach... περισσότερα »
Adenoidal follicular T helper cells
provide stronger B-cell help than those from tonsils by Matthew C. Morris, Kevin Kozara, Frank Salamone, Margo Benoit, Michael E. Pichichero via The Laryngoscope Objectives/Hypothesis The tonsils and adenoids are secondary lymphoid organs, where antigen processing and immune cell development occur to control bacterial colonization and infection in the upper respiratory tract. Both organs are abundant in follicular T helper cells (TFH), a subset of T cells specialized for promoting B-cell development. There are no prior studies on differences between the immune cells of the tonsils an...περισσότερα »
Non-dystonic embouchure problems (NED) versus embouchure dystonia (ED)
Evaluation of embouchure dysfunction: Experience of 139 patients at a single center by Pichet Termsarasab, Steven J. Frucht via The Laryngoscope Objectives/Hypothesis Our aims are to 1) illustrate the complexity and phenomenological richness of the embouchure; 2) delineate the main clinical features of non-dystonic embouchure problems (NED) versus embouchure dystonia (ED); and 3) provide a practical framework for physicians who may encounter a patient with embouchure dysfunction. Study Design We performed retrospective chart and video review and report 139 instrumentalists with embouc... περισσότερα »
E-cadherin and β-catenin overexpression in laryngeal squamous cell carcinoma
The prognostic role of by Antonio Greco, Armando De Virgilio, Maria Ida Rizzo, Fabio Pandolfi, Davide Rosati, Marco de Vincentiis via The Laryngoscope Objectives/Hypothesis Epithelial-to-mesenchymal transition (EMT) consists of a rapid and reversible change in the cellular phenotype toward the mesenchymal cell phenotype that facilitates cell migration and invasion of the tumor into surrounding tissues followed by metastasis. In the present study, we sought to determine the clinical significance of E-cadherin, N-cadherin, β-catenin, α-catenin, γ-catenin, caveolin-1, and vimentin in a ... περισσότερα »
[Impact of Microsurgical Exstirpation of Vestibular Schwannomas on the Sense of Taste].
*[Impact of Microsurgical Exstirpation of Vestibular Schwannomas on the Sense of Taste].* Laryngorhinootologie. 2015 Oct 28; Authors: Boeßert P, Hempel JM, van Ewijk R, Mann WJ, Haxel BR Abstract Patients with single sided vestibular schwannoma may report about a taste dysfunction apart from the well known cardinal symptoms. Very few data are published so far on that topic. The aim of this study was to investigate the influence of microsurgery for vestibular schwannomas on taste perception prospectively using a well validated taste test. 25 patients could be included in the stud...περισσότερα »
Postmarketing Safety Surveillance and Reevaluation of Danhong Injection: Clinical Study of 30888 Cases.
*Postmarketing Safety Surveillance and Reevaluation of Danhong Injection: Clinical Study of 30888 Cases.* Evid Based Complement Alternat Med. 2015;2015:610846 Authors: Li XL, Tang JF, Li WX, Li CX, Zhao T, Zhao BC, Wang Y, Zhang H, Chen XF, Xu T, Zhu MJ Abstract Traditional Chinese medicine injections (TCMIs) have played an irreplaceable role for treating some clinical emergency, severe illness, and infectious diseases in China. In recent years, the incidence rates of adverse drug reactions (ADRs) of TCMIs have increased year by year. Danhong injection (DHI) is one representativ...περισσότερα »
Anatomical relationship between BL23 and the posterior ramus of the L2 spinal nerve.
*Anatomical relationship between BL23 and the posterior ramus of the L2 spinal nerve.* Acupunct Med. 2015 Oct 27; Authors: Umemoto K, Saito T, Naito M, Hayashi S, Yakura T, Steinke H, Nakano T Abstract BACKGROUND: The acupuncture point BL23 is located in the region of the posterior ramus of the second lumbar spinal nerve (L2) and has historically been used to treat conditions such as lower back pain, pollakiuria, erectile dysfunction, dysmenorrhoea, tinnitus, and vertigo. Some of these treatment effects have been hypothesised to be mediated by the sympathetic nervous system. It... περισσότερα »
[Clinical analysis of Ginkgo biloba injection combined with traditional therapy in treatment of explosive deafness].
*[Clinical analysis of Ginkgo biloba injection combined with traditional therapy in treatment of explosive deafness].* Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2015 Apr;33(4):279-81 Authors: Tan J, Peng H Abstract OBJECTIVE: To investigate the clinical efficacy of Ginkgo biloba injection combined with traditional therapy in the treatment of explosive deafness. METHODS: Fifty-six (98 ears) participants who were all coal miners were selected. These patients were diagnosed with explosive deafness. and admitted to the otolaryngology department of our hospital from May 2010 to ...περισσότερα »
The clinical characteristics of congenital laryngeal saccular cysts.
*The clinical characteristics of congenital laryngeal saccular cysts.* Acta Otolaryngol. 2015 Oct 27;:1-4 Authors: Xiao Y, Wang J, Ma L, Han D Abstract CONCLUSION: The first step when treating newborns and infants with hoarseness and dyspnea is to consider the possibility of CLSCs. The appropriate operation can then be chosen based on the cyst sub-type. Complete resection of the cyst wall is the key to preventing recurrence. BACKGROUND: A laryngeal saccular cyst is an unusual congenital lesion that appears clinically during the neonatal period or early infancy. Because few report...περισσότερα »
Tongue motor training support system.
[image: http:--ieeexplore.ieee.org-images-ieee_p] Related Articles *Tongue motor training support system.* Conf Proc IEEE Eng Med Biol Soc. 2014;2014:3582-5 Authors: Sasaki M, Onishi K, Nakayama A, Kamata K, Stefanov D, Yamaguchi M Abstract In this paper, we introduce a new tongue-training system that can be used for improvement of the tongue's range of motion and muscle strength after dysphagia. The training process is organized in game-like manner. Initially, we analyzed surface electromyography (EMG) signals of the suprahyoid muscles of five subjects during tongue-training moti...περισσότερα »
Dysphagia Post Subcortical and Supratentorial Stroke.
*Dysphagia Post Subcortical and Supratentorial Stroke.* J Stroke Cerebrovasc Dis. 2015 Oct 21; Authors: Wan P, Chen X, Zhu L, Xu S, Huang L, Li X, Ye Q, Ding R Abstract BACKGROUND: Studies have recognized that the damage in the subcortical and supratentorial regions may affect voluntary and involuntary aspects of the swallowing function. The current study attempted to explore the dysphagia characteristics in patients with subcortical and supratentorial stroke. METHODS: Twelve post first or second subcortical and supratentorial stroke patients were included in the study. The locati...περισσότερα »
Adenoid cystic carcinoma,adenocarcinoma,acinic cell carcinoma,basal cell adenocarcinoma, carcinoma-ex-pleomorphic adenoma,mucoepidermoid carcinoma and salivary duct carcinoma
Outcome analysis of 215 patients with parotid gland tumors: a retrospective cohort analysis by Boban Erovic via Journal of Otolaryngology - Head & Neck Surgery Background: To identify prognostic factors in patients with parotid gland carcinomas who were treated at the Princess Margaret Hospital. Methods: Clinical outcome of two hundred fifteen patients with malignancies of the parotid gland was evaluated over a 16-year period. Results: Two-hundred-fifteen patients with adenoid cystic carcinoma (n = 20), adenocarcinoma (n = 19), acinic cell carcinoma (n = 62), basal cell adenocarcinom...περισσότερα »
Allergic Fungal Rhinosinusitis and the Unified Airway
: the Role of Antifungal Therapy in AFRS via Current Allergy and Asthma Reports AbstractAllergic fungal sinusitis (AFS) or rhinosinusitis (AFRS) is a form of polypoid chronic rhinosinusitis that is believed to be due to hypersensitivity to fungal antigens. The disease is characterized by type 1 hypersensitivity to fungal allergens, dramatically elevated total serum IgE, accumulation of thick eosinophil-laden mucin with non-invasive fungal hyphae within the paranasal sinuses, nasal polyposis, and sinus bony remodeling. Because of many clinicopathologic similarities to allergic broncho... περισσότερα »
Ablepharon-Macrostomia Syndrome with Amniotic Membrane Grafting
A Case Report of via COP : Last 10 articles We describe a rare case of an infant who was born with multiple congenital anomalies, including the absence of eyelids. This patient had many dysmorphic features consistent with a severe phenotype of ablepharon-macrostomia syndrome (AMS) including a fish-like appearance of the mouth, rudimentary ears, absence of body hair, thin skin, absent nipples, abdominal distension, and genital abnormalities. Upon presentation, there was severe exposure keratopathy causing large bilateral sterile ulcers culminating in corneal melting of both eyes. An ... περισσότερα »
A national trauma capacity assessment of Haiti
Journal of Surgical Research from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1jTzeIi via IFTTT
Task-shifting using a pain management protocol in an emergency care service: nurses perception through the eye of the Rogers's diffusion of innovation theory
Pain Management Nursing from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLqxf via IFTTT
Antenatal pelvic floor biometry is related to levator ani muscle injury
Ultrasound in Obstetrics & Gynecology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLq0j via IFTTT
Focused transesophageal echocardiography by emergency physicians is feasible and clinically influential: observational results from a novel ultrasound program
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLptb via IFTTT
Many young heart attack patients, especially women, unaware of risk
Yale School of Medicine News from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLoWb via IFTTT
Risk factors for mortality despite early protocolized resuscitation for severe sepsis and septic shock in the emergency department
Journal of Critical Care from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1jTz8jU via IFTTT
Aconitum alkaloid poisoning because of contamination of herbs by aconite roots
Phytotherapy Research from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLn4G via IFTTT
Miniplate osteosynthesis for mandibular angle fractures – a retrospective comparative study of 3 concepts in a temporal cohort
Journal of Cranio-Maxillofacial Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1jTz3Nc via IFTTT
Probable nonconvulsive status epilepticus with the use of high-dose continuous infusion ceftazidime
Journal of Pharmacy Practice from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1jTz6s6 via IFTTT
The effect of osteoarthritis on functional outcome following hemiarthroplasty for femoral neck fracture: A prospective observational study
BMC Musculoskeletal Disorders from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLixT via IFTTT
The comparison of procalcitonin guidance administer antibiotics with empiric antibiotic therapy in critically ill patients admitted in intensive care unit
Acta Medica Iranica from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLihi via IFTTT
Symptoms associated with button batteries injuries in children: An epidemiological review
International Journal of Pediatric Otorhinolaryngology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLhtQ via IFTTT
Helmet ownership and use among skateboarders: Utilisation of the Health Belief Model
Health Education Journal from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLfCj via IFTTT
Evaluation and treatment of pericarditis: A systematic review
JAMA from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1jTyTW6 via IFTTT
Needs assessment of Hurricane Katrina evacuees residing temporarily in Dallas
Community Mental Health Journal from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLey6 via IFTTT
Derivation of candidate clinical decision rules to identify infants at risk for central apnea
Pediatrics from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1jTySBo via IFTTT
Linking social media and medical record data: A study of adults presenting to an academic, urban emergency department
BMJ Quality & Safety from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1jTyS4g via IFTTT
Prospective nationwide outcome audit of surgery for suspected acute appendicitis
British Journal of Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1jTyOBF via IFTTT
Discovery could lead to new way to combat deadly effects of diarrhea
UF Health from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RfLaOV via IFTTT
Lead Can Make Halloween Quite Scary
[image: istock_000010230329_medium__1_3.jpg] Lead is one of the scarier metals. It is a naturally occurring bluish-gray metal found in small amounts in the earth's crust. But beware: lead is toxic, especially if ingested by young children and can cause adverse health effects. Even at low levels of exposure, lead can affect a child's mental and physical growth. Lead Read the rest of this article The post Lead Can Make Halloween Quite Scary appeared first on Accelerating Science. from Biomedical Engineering via ola Kala on Inoreader http://ift.tt/1WjyflK via IFTTT
What’s Wrong With That Plastic Pumpkin?
[image: lfk_2015_lppw_logo-white_background.png] Was there a product failure because of a polymer process problem? This weekend you will see many bright orange plastic pumpkins filled with candy and treats. These pumpkins are usually made of the thermoplastic family of polymers. According to Plastics Europe, the Association of Plastics Manufacturers, plastics are derived from organic products. The materials used Read the rest of this article The post What's Wrong With That Plastic Pumpkin? appeared first on Accelerating Science. from Biomedical Engineering via ola Kala on Inor...περισσότερα »
The efficacy of continuous subcostal transversus abdominis plane block for analgesia after living liver donation: a retrospective study
Abstract Purpose Postoperative pain management for living liver donors has become a major concern as a result of the increasing number of living liver donations. Transversus abdominis plane (TAP) block has been known to provide effective analgesia for abdominal surgery. The aim of this study was to evaluate the efficacy of ultrasound-guided continuous subcostal TAP block as a part of a multimodal analgesic regimen in comparison with conventional intravenous (IV) fentanyl-based analgesia in living liver donors. Methods Thirty-two donors were retrospectively classified into either t... περισσότερα »
Music Perception Influences Language Acquisition: Melodic and Rhythmic-Melodic Perception in Children with Specific Language Impairment.
*Music Perception Influences Language Acquisition: Melodic and Rhythmic-Melodic Perception in Children with Specific Language Impairment.* Behav Neurol. 2015;2015:606470 Authors: Sallat S, Jentschke S Abstract Language and music share many properties, with a particularly strong overlap for prosody. Prosodic cues are generally regarded as crucial for language acquisition. Previous research has indicated that children with SLI fail to make use of these cues. As processing of prosodic information involves similar skills to those required in music perception, we compared music perce...περισσότερα »
Emotional language is all right: Emotional prosody reduces hemispheric asymmetry for linguistic processing.
*Emotional language is all right: Emotional prosody reduces hemispheric asymmetry for linguistic processing.* Laterality. 2015 Oct 27;:1-17 Authors: Godfrey HK, Grimshaw GM Abstract In an influential paper, Bryden and MacRae [(1989). Dichotic laterality effects obtained with emotional words. Neuropsychiatry, Neuropsychology, and Behavioral Neurology, 1, 171-176] introduced a dichotic listening task that allowed for the assessment of linguistic and prosodic processing asymmetries using the same stimuli. The task produces a robust right ear advantage (REA) for linguistic processin...περισσότερα »
SMACC-Dub Registration Opens Tomorrow
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
[image: ITS-REGO-TIME.png?resize=1500%2C750] The countdown has begun: #smaccDUB registration opens next week! At last the final countdown has begun with less than 1 days to go until registration opens for SMACC Dublin. Given the multitude of different time zones, the best way to be sure you don't miss out is to synchronize your alarms with the countdown […] EMCrit by emcrit. from #Rehabilitation via ola Kala on Inoreader http://ift.tt/1LZI4yi via IFTTT
Direct restoration modalities of fractured central maxillary incisors: A multi-levels validated finite elements analysis with in vivo strain measurements
Publication date: Available online 28 October 2015 *Source:*Dental Materials Author(s): Apicella Davide, Aversa Raffaella, Tatullo Marco, Simeone Michele, Jamaluddin Syed, Marrelli Massimo, Ferrari Marco, Apicella Antonio ObjectiveTo quantify the influence of fracture geometry and restorative materials rigidity on the stress intensity and distribution of restored fractured central maxillary incisors (CMI) with particular investigation of the adhesive interfaces. Ancillary objectives are to present an innovative technology to measure the in vivo strain state of sound maxillary incisor... περισσότερα »
From a pathologist́s point of view: histiocytic cells in Hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma
Publication date: Available online 28 October 2015 *Source:*Pathology - Research and Practice Author(s): Sylvia Hartmann While tumor cells were the focus of research for many years, only recently have attempts been made to understand the role of the reactive bystander cells in malignant lymphomas. In certain types of lymphomas, such as Hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma, more than 90% of the infiltrate represent non-neoplastic cells, and these have important functions for the development and progression of the tumor. Among the bystander cells are histi... περισσότερα »
An Epithelial to Mesenchymal Transition programme does not usually drive the phenotype of Invasive Lobular Carcinomas
[image: cover.gif?v=1&s=4840627b9f333ca61aa678f1] Abstract Epithelial to mesenchymal transition (EMT) is a cellular phenotype switching phenomenon, which occurs during normal development and is proposed to promote tumour cell invasive capabilities during tumour progression. Invasive lobular carcinoma (ILC) is a histological special type of breast cancer with a peculiar aetiology – the tumour cells display an invasive growth pattern, with detached, single cells or single-files of cells, and a canonical feature is the loss of E-cadherin expression. These characteristics are indicat... περισσότερα »
Diverse routes to liver regeneration
Abstract The liver's ability to regenerate is indisputable, for example after a two-thirds partial hepatectomy in rats all residual hepatocytes can divide, questioning the need for a specific stem cell population. On the other hand, there is a potential stem cell compartment in the canals of Hering, giving rise to ductular reactions composed of hepatic progenitor cells (HPCs) when the liver's ability to regenerate is hindered by replicative senescence, but the functional relevance of this response has been questioned. Several papers now clarify regenerative mechanisms operative in ... περισσότερα »
Communication: First results of cases series of one-stage repair of gastroschisis using human acellular dermal matrix in 7 neonates
Publication date: Available online 28 October 2015 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Tongsheng Ma, Hongwei Zhang, Fengli Liu, Fang Su, Zhandong Zeng The study aimed to report the efficacy of one-stage abdominal wall repair using human acellular dermal matrix (HADM) patch in neonates with gastroschisis. We retrospectively reviewed 7 patients undergoing abdominal wall defect repair with one-stage HADM technique between May 2008 and November 2012. The urinary bladder pressure (UBP) in all patients was reduced (mean: 18.66 cm H2O) postoperatively.... περισσότερα »
Tongue motor training support system.
[image: http:--ieeexplore.ieee.org-images-ieee_p] Related Articles *Tongue motor training support system.* Conf Proc IEEE Eng Med Biol Soc. 2014;2014:3582-5 Authors: Sasaki M, Onishi K, Nakayama A, Kamata K, Stefanov D, Yamaguchi M Abstract In this paper, we introduce a new tongue-training system that can be used for improvement of the tongue's range of motion and muscle strength after dysphagia. The training process is organized in game-like manner. Initially, we analyzed surface electromyography (EMG) signals of the suprahyoid muscles of five subjects during tongue-training moti...περισσότερα »
The Pooling-score (P-score): inter- and intra-rater reliability in endoscopic assessment of the severity of dysphagia.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *The Pooling-score (P-score): inter- and intra-rater reliability in endoscopic assessment of the severity of dysphagia.* Acta Otorhinolaryngol Ital. 2014 Apr;34(2):105-10 Authors: Farneti D, Fattori B, Nacci A, Mancini V, Simonelli M, Ruoppolo G, Genovese E Abstract This study evaluated the intra- and inter-rater reliability of the Pooling score (P-score) in clinical endoscopic evaluation of severity of swallowing disorder, considering excess residue in the pharynx and larynx. The score (minimum 4 - maximum 11) is obtained by... περισσότερα »
A systematic review of tongue base suspension techniques as an isolated procedure or combined with uvulopalatopharyngoplasty in obstructive sleep apnea.
*A systematic review of tongue base suspension techniques as an isolated procedure or combined with uvulopalatopharyngoplasty in obstructive sleep apnea.* Eur Arch Otorhinolaryngol. 2015 Oct 27; Authors: Bostanci A, Turhan M Abstract We aimed to evaluate existing research into the effectiveness and safety of two tongue base suspension (TBS) techniques (Repose(®) system and modified TBS) with or without uvulopalatopharyngoplasty (UPPP) in obstructive sleep apnea. The literature review was performed using PubMed database. Searched terms used included the keywords "sleep apnea", "s... περισσότερα »
Translation and validation of EORTC QLQ-H&N 35 into Moroccan Arabic for ENT head and neck cancer patients in Morocco.
*Translation and validation of EORTC QLQ-H&N 35 into Moroccan Arabic for ENT head and neck cancer patients in Morocco.* Eur Arch Otorhinolaryngol. 2015 Oct 27; Authors: Ouattassi N, Benmansour N, ElFakir S, Nejjari C, Alami MN Abstract Disease-specific quality of life (QOL) measures have enhanced the capacity of outcome measures to evaluate subtle changes and differences between groups. As many of the QOL measures have been developed in English, they require translation to ensure their usefulness in a multi-cultural and/or international society. Published guidelines provide forma... περισσότερα »
Early laryngeal outcome of prolonged intubation using an anatomical tube: a double blind, randomised study.
*Early laryngeal outcome of prolonged intubation using an anatomical tube: a double blind, randomised study.* Eur Arch Otorhinolaryngol. 2015 Oct 27; Authors: Nordang L, Lindholm CE, Larsson J, Linder A Abstract The objective of this study was to study the short-term impact on larynx by a newly designed anatomical tube. A prospective randomised trial of a newly designed anatomical tube versus a standard endotracheal tube in patients operated under general anaesthesia for at least 12 h. Seventy adults were included and randomised to either type of tube. The patients were evaluated... περισσότερα »
Oral Motor Intervention Improved the Oral Feeding in Preterm Infants: Evidence Based on a Meta-Analysis With Trial Sequential Analysis.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Oral Motor Intervention Improved the Oral Feeding in Preterm Infants: Evidence Based on a Meta-Analysis With Trial Sequential Analysis.* Medicine (Baltimore). 2015 Aug;94(31):e1310 Authors: Tian X, Yi LJ, Zhang L, Zhou JG, Ma L, Ou YX, Shuai T, Zeng Z, Song GM Abstract Oral feeding for preterm infants has been a thorny problem worldwide. To improve the efficacy of oral feeding in preterm infants, oral motor intervention (OMI), which consists of nonnutritive sucking, oral sti... περισσότερα »
[HPV-associated head and neck cancer : Mutational signature and genomic aberrations].
*[HPV-associated head and neck cancer : Mutational signature and genomic aberrations].* HNO. 2015 Oct 27; Authors: Wagner S, Würdemann N, Hübbers C, Reuschenbach M, Prigge ES, Wichmann G, Hess J, Dietz A, Dürst M, Tinhofer I, von Knebel-Döberitz M, Wittekindt C, Klussmann JP Abstract A significantly increasing proportion of oropharyngeal head and neck carcinomas (OSCC) in North America and Europe are associated with human papillomavirus (HPV) infections. HPV-related OSCC is regarded as a distinct tumor type with regard to its cellular, biologic, and clinical characteristics. Pa...περισσότερα »
Measuring Sun exposure in Epidemiological Studies: matching the method to the research question
Publication date: Available online 28 October 2015 *Source:*Journal of Photochemistry and Photobiology B: Biology Author(s): Laura King, Fan Xiang, Ashwin Swaminathan, Robyn M. Lucas Sun exposure has risks and benefits for health. Testing these associations requires tools for measuring sun exposure that are feasible and relevant to the time-course of the health outcome. Recent sun exposure, e.g. the last week, is best captured by dosimeters and sun diaries. These can also be used for medium-term sun exposure e.g. over several weeks, but incur a high participant burden. Self-reported ...περισσότερα »
Chlorin e6 mediated photodynamic effect diminishes therapeutic potential of 5-aza-2′-deoxycytidine based whole-tumour-cell vaccine in mice bearing squamous cell carcinoma SCCVII
Publication date: Available online 28 October 2015 *Source:*Journal of Photochemistry and Photobiology B: Biology Author(s): Joanna Marczynska, Magdalena Banas, Krzysztof Guzik, Michal Koltun, Pawel Majewski, Joanna Cichy, Martyna Krzykawska-Serda, Anna Makarska, Mateusz Kwitniewski After years of setbacks, therapeutic cancer vaccines have become an alternative treatment option. Among the diversity of targeted tumour associated antigens (TAA), cancer-testis antigens (CTAs) are promising targets for cancer immunotherapy because they are highly immunogenic; meanwhile, they are express... περισσότερα »
Dysphagia Post Subcortical and Supratentorial Stroke.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
*Dysphagia Post Subcortical and Supratentorial Stroke.* J Stroke Cerebrovasc Dis. 2015 Oct 21; Authors: Wan P, Chen X, Zhu L, Xu S, Huang L, Li X, Ye Q, Ding R Abstract BACKGROUND: Studies have recognized that the damage in the subcortical and supratentorial regions may affect voluntary and involuntary aspects of the swallowing function. The current study attempted to explore the dysphagia characteristics in patients with subcortical and supratentorial stroke. METHODS: Twelve post first or second subcortical and supratentorial stroke patients were included in the study. The locati...περισσότερα »
Tongue motor training support system.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
[image: http:--ieeexplore.ieee.org-images-ieee_p] Related Articles *Tongue motor training support system.* Conf Proc IEEE Eng Med Biol Soc. 2014;2014:3582-5 Authors: Sasaki M, Onishi K, Nakayama A, Kamata K, Stefanov D, Yamaguchi M Abstract In this paper, we introduce a new tongue-training system that can be used for improvement of the tongue's range of motion and muscle strength after dysphagia. The training process is organized in game-like manner. Initially, we analyzed surface electromyography (EMG) signals of the suprahyoid muscles of five subjects during tongue-training moti...περισσότερα »
The Pooling-score (P-score): inter- and intra-rater reliability in endoscopic assessment of the severity of dysphagia.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *The Pooling-score (P-score): inter- and intra-rater reliability in endoscopic assessment of the severity of dysphagia.* Acta Otorhinolaryngol Ital. 2014 Apr;34(2):105-10 Authors: Farneti D, Fattori B, Nacci A, Mancini V, Simonelli M, Ruoppolo G, Genovese E Abstract This study evaluated the intra- and inter-rater reliability of the Pooling score (P-score) in clinical endoscopic evaluation of severity of swallowing disorder, considering excess residue in the pharynx and larynx. The score (minimum 4 - maximum 11) is obtained by... περισσότερα »
Nature Immunology
*Nature Immunology* *Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA* Anna-Maria Herzner, *et al.* *Nature Reviews Immunology* *Emerging cytokine networks in colorectal cancer* Nathan R. West, Sarah McCuaig, *et al.* *Mucosal Immunology* *Human milk proresolving mediators stimulate resolution of acute inflammation* H Arnardottir, S K Orr, J Dalli & C N Serhan *Immunology & Cell Biology* *Lethal giant larvae-1 deficiency enhances the CD8+ effector T-cell response to antigen challenge in vivo* Kelly M Ramsbottom, Faruk Sacirb...περισσότερα »
Evidence that the talk test can be used to regulate exercise intensity.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Evidence that the talk test can be used to regulate exercise intensity.* J Strength Cond Res. 2015 May;29(5):1248-54 Authors: Woltmann ML, Foster C, Porcari JP, Camic CL, Dodge C, Haible S, Mikat RP Abstract The Talk Test (TT) has been shown to be a surrogate of the ventilatory threshold and to be a viable alternative to standard methods of prescribing exercise training intensity. The TT has also been shown to be responsive to manipulations known to change physiologic function including blood donation and trainin... περισσότερα »
Reconstruction of the lower vermilion with a musculomucosal flap from the upper lip in the repair of extensive lower lip and chin defects.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Reconstruction of the lower vermilion with a musculomucosal flap from the upper lip in the repair of extensive lower lip and chin defects.* J Craniofac Surg. 2014 Sep;25(5):1855-8 Authors: Rong L, Lan SJ, Zhang D, Wang WS, Liu C, Peng WH Abstract In the repair of extensive lower lip and chin defects, the reconstruction of vermilion at the same time is a great challenge to plastic surgeons. We describe a novel method for the reconstruction of lower vermilion with musculomucosal flap from the upper lip in the repair...περισσότερα »
Sphingosine-1-Phosphate and Its Receptors: A Mutual Link between Blood Coagulation and Inflammation
Sphingosine-1-phosphate (S1P) is a versatile lipid signaling molecule and key regulator in vascular inflammation. S1P is secreted by platelets, monocytes, and vascular endothelial and smooth muscle cells. It binds specifically to a family of G-protein-coupled receptors, S1P receptors 1 to 5, resulting in downstream signaling and numerous cellular effects. S1P modulates cell proliferation and migration, and mediates proinflammatory responses and apoptosis. In the vascular barrier, S1P regulates permeability and endothelial reactions and recruitment of monocytes and may modulate ath... περισσότερα »
Rapid Exercise-Induced Mobilization of Dendritic Cells Is Potentially Mediated by a Flt3L- and MMP-9-Dependent Process in Multiple Sclerosis
In healthy individuals, one exercise bout induces a substantial increase in the number of circulating leukocytes, while their function is transiently suppressed. The effect of one exercise bout in multiple sclerosis (MS) is less studied. Since recent evidence suggests a role of dendritic cells (DC) in the pathogenesis of MS, we investigated the effect of one combined endurance/resistance exercise bout on the number and function of DC in MS patients and healthy controls. Our results show a rapid increase in the number of DC in response to physical exercise in both MS patients and c... περισσότερα »
[HPV infection in oral, pharyngeal and laryngeal papillomas].
*[HPV infection in oral, pharyngeal and laryngeal papillomas].* HNO. 2015 Oct 27; Authors: Andratschke M, Hagedorn H, Nerlich AG Abstract BACKGROUND: HPV infections play a major role in the pathogenesis of squamous cell carcinomas of the head and neck. Regarding benign papillomas, the role of HPV is still uncertain. MATERIALS AND METHODS: To clarify this issue, 100 exophytic papillomas of the oral cavity, pharynx and larynx were subjected to histopathological and molecular pathological examination. Excision biopsies were taken from 62 male and 38 female patients with an age range...περισσότερα »
[Submental artery island flaps for reconstruction in the head and neck region].
*[Submental artery island flaps for reconstruction in the head and neck region].* HNO. 2015 Oct 27; Authors: Bruchhage KL, Wollenberg B, Schröder U Abstract BACKGROUND: Reconstruction of defects after extirpation of head and neck neoplasms is a highly challenging and complex surgical undertaking. Commonly used techniques, such as the radial forearm flap or anterior lateral thigh flap, have numerous disadvantages, e.g., donor-site morbidity, poor color match for cutaneous reconstruction, and excessive tissue bulk for intraoral reconstruction. Use of a submental artery island fla...περισσότερα »
Evaluation of pharyngeal function in dogs with laryngeal paralysis before and after unilateral arytenoid lateralization.
*Evaluation of pharyngeal function in dogs with laryngeal paralysis before and after unilateral arytenoid lateralization.* Vet Surg. 2015 Oct 28; Authors: Andrade N, Kent M, Howerth EW, Radlinsky MG Abstract OBJECTIVE: To evaluate pharyngeal and laryngeal function using esophagography, topical pharyngeal/laryngeal sensitivity testing, and electromyography (EMG) in normal and dogs with idiopathic laryngeal paralysis (ILP) before and after unilateral arytenoid lateralization. STUDY: Prospective controlled cohort study. ANIMALS: Dogs with laryngeal paralysis (ILP; n = 8) and age/bree... περισσότερα »
Comparative analysis of clinical profile: Chronic cough vs paradoxical vocal fold motion.
*Comparative analysis of clinical profile: Chronic cough vs paradoxical vocal fold motion.* Respir Med. 2015 Oct 22; Authors: Hartley NA, Petty BE, Johnson B, Thibeault SL Abstract BACKGROUND: Ongoing contention surrounding typical demographic and clinical attributes of chronic cough (CC) and paradoxical vocal fold motion (PVFM) impedes timely diagnosis and optimum patient care. Designed to reduce preventable patient morbidity through improved recognition and differentiation, the current study aimed to determine representative clinical profiles for CC and PVFM, with identificati...περισσότερα »
Gastric remnant cancer: A distinct entity or simply another proximal gastric cancer?
Background The purpose of this study was to compare outcomes following resection of gastric remnant (GRC) and conventional gastric cancer. Methods Patients who underwent resection for gastric cancer in 8 academic institutions from 2000–2012 were evaluated to compare morbidity, mortality, and survival based on history of prior gastrectomy. Results Of the 979 patients who underwent gastrectomy with curative-intent during the 12-year study period, 55 patients (5.8%) presented with GRC and 924 patients (94.4%) presented with conventional gastric cancer. Patients with GRC were sligh...περισσότερα »
Previous radiation for prostate neoplasm alters surgical and oncologic outcomes after rectal cancer surgery
Background Previous radiation for prostate cancer (PC) contra-indicates neoadjuvant chemoradiotherapy for rectal cancer (RC) because of risk of cumulative radiation dose toxicity. Postoperative outcomes after proctectomy have not been well studied in these patients who did not receive optimal treatment. Methods Eighty-four consecutive male patients underwent surgery for stage II–III mid or low RC between 2002 and 2011. Patients who previously received radiation for PC (n = 8) and patients who had not previously undergone radiation for PC but who received neoadjuvant chemoradiothe... περισσότερα »
Cytocompatibility of the selected calcium phosphate based bone cements: comparative study in human cell culture
Abstract Calcium phosphate cements (CPC) are valuable bone fillers. Recently they have been also considered as the basis for drug-, growth factors- or cells-delivery systems. Broad possibilities to manipulate CPC composition provide a unique opportunity to obtain materials with a wide range of physicochemical properties. In this study we show that CPC composition significantly influences cell response. Human bone derived cells were exposed to the several well-characterized different cements based on calcium phosphates, magnesium phosphates and calcium sulfate hemihydrate (CSH). Ce...περισσότερα »
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