Σφακιανάκης Αλέξανδρος
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Πέμπτη 22 Οκτωβρίου 2015

OtoRhinoLaryngology New Articles & Online Journals,October 22nd,2015


Neurogenic oropharyngeal dysphagia (OPD) : stroke and Parkinson's disease

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
Management of oropharyngeal neurogenic dysphagia in adults.Miles, Anna; Allen, Jacqui, 2015-10-20 07:00:00 AM Purpose of review: This article reviews recent literature in the management of neurogenic oropharyngeal dysphagia (OPD) including assessment processes and treatments, with a specific focus on OPD as a result of stroke and Parkinson's disease. Recent findings: A large number of high-quality systematic reviews were published that provide an excellent summary of current evidence across assessment and treatment of swallowing disorders. There is building interest and knowledge in ...περισσότερα »

Pediatric tracheotomy decannulation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
: a protocol for success.Knollman, Philip D.; Baroody, Fuad M., 2015-10-20 07:00:00 AM Purpose of review: Pediatric tracheotomy is a common procedure. Given the risk of morbidity and mortality associated with long-term placement, it is imperative that decannulation is considered once the indication for tracheotomy placement is corrected or resolved. In this article, we discuss the critical steps necessary for the assessment of readiness for decannulation, and we review the recent literature that supports several methods of evaluation that may be incorporated into a protocol for deca... περισσότερα »

Infective oesophagitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
: epidemiology, cause, diagnosis and treatment options.O’Rourke, Ashli, 2015-10-20 07:00:00 AM Purpose of review: This review summarizes recent literature pertaining to infectious oesophagitis. Recent findings: Infectious oesophagitis is an uncommon condition of the oesophagus caused by viral, bacterial or fungal agents. A compromised immune system is the most important risk factor for the development of infectious oesophagitis and HIV or AIDS and solid organ transplant patients are particularly at risk. Common symptoms of infectious oesophagitis include odynophagia and dysphagia, bu...περισσότερα »

Microbial biofilm is implicated in the mechanisms leading to chronic recalcitrant infections, implant contamination and even to dysplasia

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
The role of biofilm in chronic laryngitis and in head and neck cancer.Kinnari, Teemu J., 2015-10-20 07:00:00 AM Purpose of review: The importance of bacterial biofilm in the human body, both when associated in chronic infections and as the default mode of microbial growth in the normal flora, has been understood during the last two decades. The word biofilm has recently entered into clinical vocabulary especially in dentistry, and oral hygienists have begun to talk of oral or dental biofilm instead of oral plaque. Biofilm presence has been demonstrated widely in otorhinolaryngology, ... περισσότερα »

Caustic oesophagitis in children

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
: prevalence, the corrosive agents involved, and management from primary care through to surgery.Uygun, Ibrahim, 2015-10-20 07:00:00 AM Purpose of review: Caustic substance ingestion (CSI) remains a major health issue, particularly in developing countries, where laws are not effectively enforced. This review offers a thorough analysis of the current epidemiology, clinical features, management, treatment, and long-term complications of CSI in children. Recent findings: Strong alkalis sold in liquid and granular forms, particularly crystalline grease cleaners (concentrated sodium hydro...περισσότερα »

Viral laryngitis,Chronic cough due to postviral vagal neuropathy,Laryngeal shingles and idiopathic ulcerative laryngitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Viral laryngitis: a mimic and a monster - range, presentation, management.Dominguez, Laura M.; Simpson, C. Blake, 2015-10-20 07:00:00 AM Purpose of review: The purpose of this review is to highlight recent literature relating to the diagnosis and treatment of some less common forms of viral laryngitis. The main conditions addressed in this review are chronic cough or postviral vagal neuropathy, varicella zoster infection of the larynx, and a condition increasingly suspected as being virally induced, idiopathic ulcerative laryngitis. Recent findings: Diagnosis of these conditions requ... περισσότερα »

Adult obstructive sleep apnoea and the larynx

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Adult obstructive sleep apnoea and the larynx.Novakovic, Daniel; MacKay, Stuart, 2015-10-20 07:00:00 AM Purpose of review: The review examines current evidence and thinking regarding the relationship between the larynx and obstructive sleep apnoea (OSA) in adults. Recent findings: Drug-induced sleep endoscopy has an emerging role in the identification of laryngeal obstruction associated with sleep apnoea and may be adjunctive to awake dynamic assessment in specific cases. Nocturnal stridor and OSA is a common and treatable finding in patients with multiple system atrophy. Acromegaly ... περισσότερα »

The reconstruction of paediatric facial paralysis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Perspectives in Sharma, Pundrique R.; Zuker, Ronald M.; Borschel, Gregory H., 2015-10-20 07:00:00 AM Purpose of review: In this review article, aimed at those likely to encounter but relatively unfamiliar with paediatric facial paralysis, we summarize reconstructive options in its surgical management. Recent findings: The article looks at static and dynamic reconstructions available to address the problems encountered in the different anatomical regions of paralyzed face. Summary: Although multiple surgical options are available for each anatomical region, decision-making should be t...περισσότερα »

Chronic nasal dysfunction in children

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
: Allergic rhinitis? Infectious? What to do if neither?.Wei, Julie L., 2015-10-20 07:00:00 AM Purpose of review: To review challenges in the diagnosis, work-up, and management of healthy children who present to the otolaryngologist with nasal dysfunction. Common symptoms include chronic nasal congestion, with or without rhinorrhea, with or without previous empirically treated 'allergic rhinitis' and/or 'sinus' infection. Symptoms are often unresolved despite chronic use of intranasal steroid, antihistamine, and/or leukotriene receptor antagonists. Recent findings: There are no publis... περισσότερα »

Current Opinion in Otolaryngology & Head and Neck Surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Current Opinion in Otolaryngology & Head and Neck Surgery - Published Ahead-of-Print - Chronic nasal dysfunction in children: Allergic rhinitis? Infectious? What to do if neither?.Wei, Julie L., 2015-10-20 07:00:00 AM Purpose of review: To review challenges in the diagnosis, work-up, and management of healthy children who present to the otolaryngologist with nasal dysfunction. Common symptoms include chronic nasal congestion, with or without rhinorrhea, with or without previous empirically treated 'allergic rhinitis' and/or 'sinus' infection. Symptoms are often u... περισσότερα »

Obstructive sleep apnea and K-complex

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
K-complex From Wikipedia, the free encyclopedia [image: Stage2sleep new.svg] A *K-complex* is an electroencephalography (EEG) waveform that occurs during stage 2 ofNREM sleep. It is the "largest event in healthy human EEG". [1] They are more frequent in the first sleep cycles. K-complexes have two proposed functions:[1] first, suppressing cortical arousal in response to stimuli that the sleeping brain evaluates not to signal danger, and second, aiding sleep-based memory consolidation. The K-complex was discovered in 1937 in the private laboratories of Alfred Lee Loomis.[2] - 1 Neuro... περισσότερα »

Regional pollen allergen exposure differences may induce variable sensitization profiles that could affect allergen immunotherapy efficacy and safety

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
*Article in Press* Timothy specific IgE levels are associated with efficacy and safety of timothy grass sublingual immunotherapy tablet *Received: July 1, 2015; Received in revised form: August 26, 2015; Accepted: September 23, 2015;Published Online: October 21, 2015Maria Nolte, BSc , Domingo Barber, PhD , Jennifer Maloney, MD¶ , Ziliang Li, PhD , Amarjot Kaur, PhD , Agustin Galan, BS , Jens S. Andersen, PhD , Hendrik Nolte, MD, PhD[image: correspondence][image: email]* *¶Current affiliation: Regeneron Pharmaceuticals, Inc, Tarrytown, New York.* *Annals of Allergy, Asthma & ...περισσότερα »

Psychosis in sleep apnoea

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Aust N Z J Psychiatry. *Psychosis in sleep apnoea*. Lee S1, Chiu HF, Chen CN. Author information 1Department of Psychiatry, Chinese University of Hong Kong, Shatin, N.T. *Abstract A 30-year-old man presenting with intellectual impairment and recurrent psychotic episodes was subsequently found to have suffered from a chronically untreated obstructive sleep apnoea syndrome. Polysomnography revealed sleep fragmentation, slow wave sleep deprivation and abnormal arterial oxygen desaturation. Tonsillectomy led to complete resolution of sleep apnoea and remission of psychosis at 2 years' ... περισσότερα »

Molecular diagnosis of hereditary hearing loss

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Pediatric otolaryngology, molecular diagnosis of hereditary hearing loss: next-generation sequencing approach. by Jasper, Kayla M.; Jamshidi, Aria; Reilly, Brian K. via Current Opinion in Otolaryngology & Head and Neck Surgery - Published Ahead-of-Print Purpose of review: Sensorineural hearing loss (SNHL) is the most common sensory birth defect. The purpose of this article is to review the advances in next-generation sequencing (NGS) and molecular diagnosis of hereditary hearing loss. Recent findings: Early diagnosis and detection of SNHL is critical for the development of appropriate... περισσότερα »

The relationship between sleep and epilepsy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
*Resolution of obstructive sleep apnea with epilepsy surgery ...* *onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2008.01677.x/pdf* *File Format: PDF/Adobe Acrobat* Resolution of obstructive sleep apnea with epilepsy surgery? Expanding the relationship between sleep and epilepsy *Address correspondence to Nancy Foldvary-Schaefer, DO, Cleveland Clinic Foundation, 9500 Euclid Avenue, FA20 Cleveland, Ohio 44195, U.S.A. E-mail: foldvan@ccf.org* Summary *Recent studies suggest a higher than expected prevalence of obstructive sleep apnea (OSA) in patients with refractory epilepsy. In some c... περισσότερα »

Epilepsia

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 28 δευτερόλεπτα
- Availability of antiepileptic drugs across EuropeArton Baftiu, Cecilie Johannessen Landmark, Valent Nikaj, Inger-Lise Neslein, Svein I. Johannessen, Emilio Perucca, 2015-10-22 12:39:33 AM Summary Europe consists of 53 countries with widely different economic conditions and different political, educational, and health care systems. This study was aimed at determining the availability of antiepileptic drugs (AEDs) across Europe. An electronic questionnaire was submitted to all 43 European chapters of the International League Against Epilepsy (ILAE). Ou... περισσότερα »

Burn depth assessments by photoacoustic imaging and laser Doppler imaging

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 33 δευτερόλεπτα
Burn depth assessments by photoacoustic imaging and laser Doppler imagingTaiichiro Ida, Hideaki Iwazaki, Yasushi Kawaguchi, Satoko Kawauchi, Tsuyako Ohkura, Keiichi Iwaya, Hitoshi Tsuda, Daizoh Saitoh, Shunichi Sato, Toshiaki Iwai, 2015-10-22 12:31:21 AM Abstract Diagnosis of burn depths is crucial to determine the treatment plan for severe burn patients. However, an objective method for burn depth assessment has yet to be established, although a commercial laser Doppler imaging (LDI) system is used limitedly. We previously proposed burn depth assessment based on photoacoustic imagin... περισσότερα »

Negative pressure wound therapy limits downgrowth in percutaneous devices

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 33 δευτερόλεπτα
Negative pressure wound therapy limits downgrowth in percutaneous devicesSaranne J. Mitchell, Sujee Jeyapalina, Francesca R. Nichols, Jayant Agarwal, Kent N. Bachus, 2015-10-22 12:31:21 AM Abstract Maintenance of a soft tissue seal around percutaneous devices is challenged by the downgrowth of periprosthetic tissues—a gateway to potential infection. Since Negative Pressure Wound Therapy *(NPWT)* is used clinically to facilitate healing of complex soft tissue pathologies, it was hypothesized that NPWT could limit downgrowth of periprosthetic tissues. To test this hypothesis, 20 hairle... περισσότερα »

Wound Repair and Regeneration

Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 36 δευτερόλεπτα
- Pro-apoptotic Effect of Control-Released Basic Fibroblast Growth Factor on Skin Wound Healing in a Diabetic Mouse ModelChenyu Huang, Hakan Orbay, Morikuni Tobita, Masaaki Miyamoto, Yasuhiko Tabata, Hiko Hyakusoku, Hiroshi Mizuno, 2015-10-22 12:31:21 AM Abstract The ability of basic fibroblast growth factor (bFGF) to improve wound healing is attenuated by its short half-life in free form. This study aimed to enhance skin wound healing in a diabetes mouse model while concomitantly decreasing scar formation by using control-released bFGF together with a... περισσότερα »

The ability of basic fibroblast growth factor (bFGF) to improve wound healing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Pro-apoptotic Effect of Control-Released Basic Fibroblast Growth Factor on Skin Wound Healing in a Diabetic Mouse Model by Chenyu Huang, Hakan Orbay, Morikuni Tobita, Masaaki Miyamoto, Yasuhiko Tabata, Hiko Hyakusoku, Hiroshi Mizunovia Wound Repair and Regeneration Abstract The ability of basic fibroblast growth factor (bFGF) to improve wound healing is attenuated by its short half-life in free form. This study aimed to enhance skin wound healing in a diabetes mouse model while concomitantly decreasing scar formation by using control-released bFGF together with acidic gelatin hydrogel...περισσότερα »

The velopharynx as the site of upper airway compromise in sleep disordered breathing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 40 δευτερόλεπτα
Beyond Palatal Surgery by Oleg Froymovich via Operative Techniques in Otolaryngology In the first volume of this publication the focus was primarily directed on the velopharynx as the site of upper airway compromise in sleep disordered breathing. However, soon after the initial surgeries of soft palate in the early eighties, investigators realized that the sites of upper airway obstruction exist at multiple levels. Pioneering work of Friedman, Borowiecki and Sassin(Muller's maneuver), and Moore provided initial tools to evaluate awake airway in an attempt to extrapolate this knowledge... περισσότερα »

Electromagnetic navigation bronchoscopy (ENB)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 40 δευτερόλεπτα
Electromagnetic Navigational Bronchoscopy: An Effective and Safe Approach to Diagnose Peripheral Lung Lesions Unreachable by Conventional Bronchoscopy in High-Risk Patients by Mahajan, Amit K.; Patel, Shruti; Hogarth, Douglas Kyle; Wightman, Rachel via Journal of Bronchology & Interventional Pulmonology - Most Popular Articles Purpose : The purpose of this study was to investigate the diagnostic yield and safety of electromagnetic navigation bronchoscopy (ENB) on peripheral lung lesions deemed otherwise unreachable using conventional bronchoscopy in high-risk patients. Methods : This... περισσότερα »

Unilateral congenital ptosis : The relationship between levator muscle function (LMF) and other eyelid parameters

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Comparison between eyelid indices of ptotic eye and normal fellow eye in patients with unilateral congenital ptosis by Abbas Bagheri, Mehdi Tavakoli, Hadi Najmi, Reza Erfanian Salim, Shahin Yazdani via Plastic, Reconstructive & Aesthetic Surgery Abstract Purpose To evaluate the relationship between levator muscle function (LMF) and other eyelid parameters in the normal and affected eyes of patients with unilateral congenital ptosis. Methods This study includes subjects with unilateral congenital upper lid ptosis who were referred for operation over a 2-year period. Patients with other... περισσότερα »

Long-Term Donor Site Morbidity after Vascularized Free Fibula Flap Harvesting

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 44 δευτερόλεπτα
: Clinical and Gait Analysis by Damien Feuvrier, Yoshimasa Sagawa, Samuel Béliard, Julien Pauchot, Pierre Decavel via Plastic, Reconstructive & Aesthetic Surgery The goal of this study was to determine the clinical morbidity and changes in gait temporal spatial parameters after harvesting of a vascularized free fibula flap. Eleven patients (mean age: 52 ± 17 years) and eleven healthy controls (mean age: 50 ± 14 years) were included in this study. The patients were assessed between 5 and 104 months after their surgery. The study consisted of a subjective functional evaluation with two ...περισσότερα »

Moderate hypofractionated stereotactic radiotherapy for meningiomas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα
Long-term outcome of via Latest Results for Strahlentherapie und Onkologie AbstractPurposeThe aim of this work was to evaluate long-term results of moderate hypofractionated stereotactic radiotherapy (hFSRT) for intracranial meningiomas. Patients and methodsIn all, 77 consecutive patients with 80 lesions were included. Median age was 65 years (range 23–82 years), male/female ratio was 21/56, and the median Karnofsky performance status was 90 (range 60–100). In 31 lesions (39 %), diagnosis was based upon clinical and radiological data; 37 lesions were histologically proven as World He...περισσότερα »

Long-term adherence to CPAP in non-sleepy OSA

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα
Article in Press Long-term adherence to continuous positive airway pressure therapy in non-sleepy sleep apnea patients Francisco Campos-Rodriguez , Montserrat Martinez-Alonso , Manuel Sanchez-de-la-Torre , Ferran Barbe[image: correspondence][image: email] on behalf of the Spanish Sleep Network *Sleep Medicine* DOI: http://dx.doi.org/10.1016/j.sleep.2015.07.038 Highlights • We analyzed long-term adherence to CPAP in non-sleepy OSA. • 64.4% of the patients had good CPAP adherence after 4 years of follow-up. • Greater OSA severity was an independent predictor of good CPAP adheren... περισσότερα »

Treatment of sleep apnea in chronic heart failure patients with auto-servo ventilation improves sleep fragmentation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα
Article in Press Treatment of sleep apnea in chronic heart failure patients with auto-servo ventilation improves sleep fragmentation: a randomized controlled trial Andrea Hetzenecker, MD , Pierre Escourrou, MD , Samuel T Kuna, MD , Frederic Series, MD , Keir Lewis, MD , Christoph Birner, MD , Michael Pfeifer, MD , Michael Arzt, MD[image: correspondence][image: email] *Sleep Medicine* DOI: http://dx.doi.org/10.1016/j.sleep.2015.08.020 Highlights • Treatment of sleep disordered breathing in chronic heart failure patients with auto-servo ventilation (ASV) reduced sleep... περισσότερα »

Pediatric Eosinophilic esophagitis (EoE)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα
High rate of failure to thrive in a pediatric cohort with eosinophilic esophagitis by Brenda Paquet, Philippe Bégin, Louis Paradis, Eric Drouin, Anne Des Roches via Annals of Allergy, Asthma & Immunology Eosinophilic esophagitis (EoE) is an allergy-associated disease that has been increasingly recognized during the past 2 decades. In children, its incidence rate could exceed that of inflammatory bowel disease, with a reported incidence up to 10 per 100,000 children per year in North America.1 Esophageal dysfunction, which is the main clinical hallmark of the disease in adults, is les... περισσότερα »

Sleep Medicine

Alexandros G. SfakianakisστοΥπνική Άπνοια και Διαταραχές ΎπνουΠριν από 50 δευτερόλεπτα
- Sleep-promoting medications in children: physician prescribing habits in southwestern ontario, canadaDirk E. Bock, Elizabeth Roach-Fox, Jamie A. Seabrook, Michael J. Rieder, Doreen Matsui, 2015-10-22 12:17:29 AM • 89% and 66% of respondents recommended sleep-promoting OTC and prescription medications.• Melatonin and antihistamines were the most commonly recommended over-the-counter medications.• Antidepressants and benzodiazepines were the most commonly prescribed medications.• 30% of respondents recommended sleep medications to otherwise healthy children with insomnia... περισσότερα »

Hospital LOS and total adjusted costs are significantly less for patients undergoing translabyrinthine acoustic neuroma resection compared to the retrosigmoid approach

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Retrosigmoid versus translabyrinthine approach to acoustic neuroma resection: A comparative cost-effectiveness analysis by Maroun T. Semaan, Cameron C. Wick, Kimberly J. Kinder, John G. Stuyt, Rebecca L. Chota, Cliff A. Megerian via The Laryngoscope Objectives/Hypothesis Approach-specific economic data of acoustic neuroma (AN) resection is lacking. The purpose of this study was to analyze and compare adjusted total hospital costs, hospital and intensive care unit (ICU) length of stay (LOS), and associated factors in AN patients undergoing resection by translabyrinthine (TL) approach v...περισσότερα »

Increased number of volatile organic compounds over malignant glottic lesions

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Increased number of volatile organic compounds over malignant glottic lesions by Hagit Shoffel-Havakuk, Idan Frumin, Yonatan Lahav, Lior Haviv, Noam Sobel, Doron Halperin via The Laryngoscope Objectives/Hypothesis Electronic noses can identify diseases, including head and neck squamous cell carcinoma (SCC) by the fingerprint of volatile organic compounds (VOCs) in exhaled air. However, whether these VOCs originated from the malignant lesion itself remains unclear. The objective was to test for the presence and properties of VOCs directly over the vocal folds in malignant and benign l...περισσότερα »

OSCC metastatic to central compartment (level 6) lymph nodes

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Oral cavity squamous cell carcinoma metastatic to central compartment (level 6) lymph nodes by Ilya Likhterov, Meghan E. Rowe, Azita S. Khorsandi, Mark L. Urken via The Laryngoscope Alterations to drainage pathways in the head and neck as a result of surgical manipulation are not well understood. We present two unusual cases of oral squamous cell carcinoma metastatic to the level 6 nodal compartment following extensive treatment. Both oral squamous cell carcinoma cases exhibited metastases to the central neck compartment following extensive surgery and radiation. Each patient had pri...περισσότερα »

Vertebrate tropomyosins : Fish tropomyosins allergens

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
*Article in Press* Are fish tropomyosins allergens? *Published Online: October 21, 2015Juan González-Fernández, MSc** ,* * Beatriz Veleiro, MD , Alvaro Daschner, PhD, MD[image: email] , Carmen Cuéllar, PhD* *Annals of Allergy, Asthma & Immunology* *DOI: http://dx.doi.org/10.1016/j.anai.2015.09.017* *Vertebrate tropomyosins are generally not allergenic, with the only exception being tilapia tropomyosin.1With a special workup of a patient with fish-induced symptoms, we found that several vertebrate tropomyosins can be allergenic.* *© 2015 American College of Allergy, Asthma & Imm... περισσότερα »

Annals of Allergy, Asthma & Immunology

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 1 ώρα
*Article in Press* Timothy specific IgE levels are associated with efficacy and safety of timothy grass sublingual immunotherapy tablet *Received: July 1, 2015; Received in revised form: August 26, 2015; Accepted: September 23, 2015;Published Online: October 21, 2015Maria Nolte, BSc, Domingo Barber, PhD, Jennifer Maloney, MD¶, Ziliang Li, PhD, Amarjot Kaur, PhD,Agustin Galan, BS, Jens S. Andersen, PhD, Hendrik Nolte, MD, PhD[image: correspondence][image: email]* *¶Current affiliation: Regeneron Pharmaceuticals, Inc, Tarrytown, New York.* *Annals of Allergy, Asthma & Immunology* *D... περισσότερα »

Multicolor flow-cytometric analysis of milk allergen-specific T-helper type 2 cells

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
*Article in Press* Multicolor flow-cytometric analysis of milk allergen-specific T-helper type 2 cells revealed coexpression of interleukin-4 with Foxp3 *Received: July 3, 2015; Received in revised form: September 23, 2015; Accepted: September 26, 2015;Published Online: October 21, 2015Kazuo Yamawaki, MD , Chisato Inuo, MD , Takayasu Nomura, MD, PhD , Kenichi Tanaka, MD, PhD , Yoichi Nakajima, MD, PhD , Yasuto Kondo, MD, PhD , Tetsushi Yoshikawa, MD, PhD , Atsuo Urisu, MD, PhD , Ikuya Tsuge, MD, PhD[image: correspondence][image: email]* *Annals of Allergy, Asthma & Immunol... περισσότερα »

Ragweed (Ambrosia) species : short ragweed (Ambrosia artemisiifolia; Amb a), giant ragweed (Ambrosia trifida; Amb t), and western ragweed (Ambrosia psilostachya; Amb p)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
*Article in Press* Short ragweeds is highly cross-reactive with other ragweeds *Received: July 2, 2015; Received in revised form: August 26, 2015; Accepted: September 20, 2015;Published Online: October 21, 2015Lars H. Christensen, PhD , Henrik Ipsen, PhD , Hendrik Nolte, MD, PhD , Jennifer Maloney, MD , Harold S. Nelson, MD , Richard Weber, MD , Kaare Lund, PhD[image: correspondence][image: email]* *Annals of Allergy, Asthma & Immunology* *DOI: http://dx.doi.org/10.1016/j.anai.2015.09.016* AbstractBackground *The most widespread ragweed (Ambrosia) species in North America are... περισσότερα »

Toxinology

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 1 ώρα
- On-site monitoring of rotenone treatment of Norwegian lakes and riversSilvio Uhlig, 2013-09-18 03:00:00 AM In the fall of 2013 we have for the second time on-site monitored the distribution of rotenone in a Norwegian river that was treated with the non-selective piscicide in order to eradicate the fish parasite Gyrodactylus salaris . Rotenone occurs naturally in the seeds and stems of several plants, especially within the Fabaceae. The compound has historically been used by indigenous people to catch fish. Read moreTop - Mechanisms involved in alternariol-indu... περισσότερα »

First olfactory fiber as an anatomical landmark for frontal sinus surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
First olfactory fiber as an anatomical landmark for frontal sinus surgery by Smita Upadhyay, Lamia Buohliqah, Gerival Vieira Junior, Bradley A. Otto, Daniel M. Prevedello, Ricardo L. Carrau viaThe Laryngoscope Objectives/Hypothesis Access to the frontal sinuses is technically challenging owing to their anterosuperior location, diverse anatomy, close proximity to critical structures and the need to work in a relatively narrow space with angled-lens endoscopes and instruments. This study attempts to study the relationship of the first olfactory fiber with the frontal sinus posterior wal... περισσότερα »

Journal of Phonetics

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
1. - Vowel space area in later childhood and adolescence: Effects of age, sex and ease of communicationOriginal Research Article - *Pages 1-14* - *Michèle Pettinato, Outi Tuomainen, Sonia Granlund, Valerie Hazan* - *- Abstract- Close research highlights- PDF (0 K)* Highlights *•* *Vowel space development and enhancement was investigated in childhood and adolescence.* *•* *A communicative spontaneous speech task was used in easy and distorted conditions.* *•* *Children's vowel spaces we... περισσότερα »

Postural influence on intracranial and cerebral perfusion pressure in ambulatory neurosurgical patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Postural influence on intracranial and cerebral perfusion pressure in ambulatory neurosurgical patientsPetersen, L. G., Petersen, J. C. G., Andresen, M., Secher, N. H., Juhler, M., 2015-10-22 11:33:10 AM We evaluated postural effects on intracranial pressure (ICP) and cerebral perfusion pressure (CPP: mean arterial pressure (MAP) - ICP) in neurosurgical patients undergoing 24-hour ICP monitoring as part of their diagnostic workup. We identified 9 patients (5 women, age 44±20 yrs.; mean±SD) who were "as normal as possible" i.e. without indication for neurosurgical intervention (e.g. f... περισσότερα »

Hemodynamic responses and baroreflex sensitivity (BRS) indices during Valsalva maneuver (VM) and head-up tilt (HUT) testing in orthostatic intolerance (OI)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
The utility of Valsalva maneuver in the diagnoses of orthostatic disorders.Palamarchuk, I. S., Baker, J. R., Kimpinski, K., 2015-10-22 11:33:10 AM Objective: 1) To assess hemodynamic responses and baroreflex sensitivity (BRS) indices during Valsalva maneuver (VM) and head-up tilt (HUT) testing in orthostatic intolerance (OI). Methods: Patients with *neurogenic orthostatic hypotension (NOH, n=26), * *postural tachycardia syndrome (POTS, n=26) and * *symptomatic orthostatic intolerance (SOI, n=14) * were compared to healthy population (Control, n=107) and inappropriate sinus tachyca...περισσότερα »

The American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

Alexandros G. SfakianakisστοEvolutionary PhysiologyΠριν από 1 ώρα
AJP: Ahead of Print - Increased placental fatty acid transporter 6 and binding protein 3 expression and fetal liver lipid accumulation in a mouse model of obesity in pregnancy.Diaz, P., Harris, J., Rosario, F. J., Powell, T. L., Jansson, T., 2015-10-22 11:33:10 AM Obesity in pregnancy is associated with increased fetal growth and adiposity, which, in part, is determined by transplacental nutrient supply. Trophoblast uptake and intracellular trafficking of lipids are dependent on placental fatty acid transport proteins (FATP), translocase (FAT/CD36) and fat... περισσότερα »

3-M syndrome patient with novel CUL7 gene mutations : Facial appearance : Triangular face, frontal bossing, an anteverted nose, dolichocephaly, and a long philtrum

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Changes in facial appearance from neonate to adult in 3-M syndrome patient with novel CUL7 gene mutations via Journal of Pediatric Endocrinology and Metabolism Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print Abstract 3-M syndrome (OMIM #273750, #612921, and #614205) is a rare autosomal recessive growth disorder that is characterized by pre- and postnatal growth retardation, normal intelligence, and characteristic faces. This syndrome also has characteristic radiological features, such as slender long bones and tall vertebral bodies. Three genes, cu...περισσότερα »

Verbal Immediate Memory

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
A SPoARC in the Dark: Spatialization in Alessandro Guida, Aurélie Leroux, Magali Lavielle-Guida, Yvonnick Noël, 2015-10-22 11:28:00 AM Abstract In 2011, van Dijck and Fias described a positional SNARC (Spatial-Numerical Association of Response Codes) effect: the SPoARC (Spatial-Positional Association of Response Codes). To-be-remembered items (e.g., numbers, words) presented centrally on a screen seemed to acquire a left-to-right spatial dimension. If confirmed, this spatialization could be crucial for immediate memory theories. However, given the intricate links between visual and s...περισσότερα »

Music Perception in Adult Users of Cochlear Implants

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
: A Brief Review by Jensen RC, Ferguson S. via Perspectives on Aural Rehabilitation and Its Instrumentation Current Issue Although cochlear implants (CIs) can provide good speech understanding in quiet, in general, users of CIs have shown poor music perception performance, particularly with regard to pitch (and hence melody). This is primarily due to the limited ability of CI processing strategies and electric stimulation to provide place pitch and fine structure information from the original input signal to the auditory nervous system of the user. Approaches such as current focusing... περισσότερα »

Brazilian Journal of Otorhinolaryngology

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
*Editoriais* *O médico e o mundo da tecnologiaBrazilian Journal of Otorhinolaryngology.2015;81:455-6PDF* *Irrigação nasal com solução salina: terapêutica ou homeopáticaBrazilian Journal of Otorhinolaryngology.2015;81:457-8PDF* *Artigos originais* *Valores de referência para o teste de identificação de sentenças dicóticas em português brasileiro segundo orelha e idadeBrazilian Journal of Otorhinolaryngology.2015;81:459-65PDF* *Efeito da estimulação contralateral nas medidas de reflectância acústicaBrazilian Journal of Otorhinolaryngology.2015;81:466-72PDF* *Acurácia da tonometria a...περισσότερα »

Aural Rehabilitation and Its Instrumentation

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
SIG 7 Perspectives on Aural Rehabilitation and Its Instrumentation Newest Issue - Coordinator's ColumnCienkowski K. , 2015-05-01 03:00:00 AM Read moreTop - Music Perception in Adult Users of Cochlear Implants: A Brief ReviewJensen RC, Ferguson S. , 2015-05-01 03:00:00 AM Although cochlear implants (CIs) can provide good speech understanding in quiet, in general, users of CIs have shown poor music perception performance, particularly with regard to pitch (and hence melody). This is primarily due to the limited ability of CI processing strategies and electric... περισσότερα »

CBCT versus MSCT-Based Models on Assessing Condylar MorphologyOriginal Research Article In Press, Accepted Manuscript, Available online 20 October 2015 Liliane Rosas Gomes, Marcelo Regis Gomes, João Roberto Gonçalves, Antônio Carlos O. Ruellas, Larry M. Wolford, Beatriz Paniagua, Erika Benavides, Lúcia Helena Soares Cevidanes

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
- CBCT versus MSCT-Based Models on Assessing Condylar MorphologyOriginal Research Article - *In Press, Accepted Manuscript*, - Liliane Rosas Gomes, Marcelo Regis Gomes, João Roberto Gonçalves, Antônio Carlos O. Ruellas, Larry M. Wolford, Beatriz Paniagua, Erika Benavides, Lúcia Helena Soares Cevidanes Abstract Objective To quantitatively compare condylar morphology using CBCT and MSCT virtual 3D surface models. Study Design The sample consisted of secondary data analysis of CBCT and MSCT scans obtained for clinical purposes from 74 patients treated with con... περισσότερα »

Invasive micropapillary salivary duct carcinoma (SDC)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
- Invasive micropapillary salivary duct carcinoma mixed with mucin-rich salivary duct carcinoma in minor salivary gland: a rare case report - *In Press, Accepted Manuscript* - Kei Tomihara, Shigeharu Miwa, Takeshi Takazakura, Yuichi Kamisaki, Makoto Noguchi AbstractBackground Invasive micropapillary salivary duct carcinoma (SDC) is a rare variant of SDC. Although several cases involving major salivary glands have been reported, no cases arising *de novo* in minor salivary glands have been reported till now. Here we report a first case of invasive micropapillary S... περισσότερα »

The effect of field of view (FOV) size and position on scatter-induced image noise in cone-beam computed tomography (CBCT)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
- Reduction of scatter-induced image noise in cone-beam CT: effect of field of view size and positionOriginal Research Article - *In Press, Accepted Manuscript*, - Ruben Pauwels, Reinhilde Jacobs, Ria Bogaerts, Hilde Bosmans, Soontra Panmekiate AbstractObjective to measure the effect of field of view (FOV) size and position on scatter-induced image noise in cone-beam computed tomography (CBCT). Study Design a PMMA phantom containing air and aluminum underwent CBCT scanning using seven FOVs, ranging between 4x4 cm and 14x10 cm, positioned both centrally and accord...περισσότερα »

Congenital Granular Cell Lesion of the Tongue

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
: A Report of Two Cases and Review of the Literature via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology [image: Clinical image of case 1 depicting a multi-lobular mass emanating from the oral ...] [image: Clinical image of case 1 demonstrating location of mass on the anterior tongue ...] 1. [image: Excision specimen of mass from case 1 demonstrates an attenuated, ...] 2. [image: Excision specimen of mass from case 1 shows strong, diffuse positivity for CD68 ...] 3. [image: Excision specimen of mass from case 1 demonstrating negative reaction for S100... περισσότερα »

Microbiology

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 15 ώρες
[image: feedamail.com] Microbiology via ola Kala on Inoreader (Sponsor this newsletter) Resistance integrons: class 1, 2 and 3 integrons As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and reported to widely spread and extended to a large variety of microorganisms. In China, as one of... περισσότερα »

The Four Square Step Test in children with cerebral palsy and Down syndrome

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 ώρες
Reliability and validity of via ScienceDirect Publication: Research in Developmental Disabilities Publication date: December 2015 *Source:*Research in Developmental Disabilities, Volume 47 Author(s): Aila Nica J. Bandong, Gilbert O. Madriaga, Edward James R. Gorgon Little is known about the measurement properties of clinical tests of stepping in different directions for children with cerebral palsy (CP) and Down syndrome (DS). The ability to step in various directions is an important balance skill for daily life. Standardized testing of this skill can yield important information for th... περισσότερα »

Journal of Dental and Allied Sciences

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρικήΠριν από 21 ώρες
Archie Cochrane: The Pioneer of Fourth Revolution of Health Care *Jayant N Palaskar* Journal of Dental and Allied Sciences 2015 4(1):1-2 Extraction: A Parameter in Bolton Ratio *Priyanka Vilas Kale, Dhiraj Rajendra Chhajed, Shivani Shailendra Khapli, Nitin Rameshchandra Tripathi, Gurjeet Kaur Gurmeet Singh Randhawa* Journal of Dental and Allied Sciences 2015 4(1):3-7 Aims: To evaluate extraction as a parameter in determination of Bolton ratio in class II division 1 cases. Materials and Methods: Thirty Class II division 1 cases were selected from the records. Bolton overall ratio was ... περισσότερα »

European Journal of Anaesthesiology (EJA) - Published Ahead-of-Print

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 22 ώρες
Postoperative shoulder pain after laparoscopic hysterectomy with deep neuromuscular blockade and low-pressure pneumoperitoneum: A randomised controlled trial. BACKGROUND: Postoperative shoulder pain remains a significant problem after laparoscopy. Pneumoperitoneum with insufflation of carbon dioxide (CO2) is thought to be the most important cause. Reduction of pneumoperitoneum pressure may, however, compromise surgical visualisation. Recent studies indicate that the use of deep neuromuscular blockade (NMB) improves surgical conditions during a low-pressure pneumoperitoneum (8 mmHg). ... περισσότερα »

Academic Radiology

Alexandros G. SfakianakisστοΑπεικονιστικήΠριν από 23 ώρες
Breast Cancer Survivors Publication date: November 2015 *Source:*Academic Radiology, Volume 22, Issue 11 Author(s): Cherie M. Kuzmiak Screening Breast MRI in Patients Previously Treated for Breast Cancer Publication date: November 2015 *Source:*Academic Radiology, Volume 22, Issue 11 Author(s): Catherine S. Giess, Patricia S. Poole, Sona A. Chikarmane, Dorothy A. Sippo, Robyn L. Birdwell Rationale and Objectives To determine the cancer detection rate and abnormal interpretation rate of screening breast magnetic resonance imaging (MRI) in previously treated breast cancer patient... περισσότερα »

Medgadget

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 23 ώρες
D Printed Titanium Sternum and Ribcage Implanted in Patient A patient in Spain suffering from chest wall sarcoma received a 3D printed replacement sternum and ribcage after many of the natural bones were surgically removed. The titanium implant was designed by Anatomics, a Melbourne, Australia firm, specifically for the unique anatomical needs of this particular... 1h Mayo Clinic hosts the #BRAINInitiative symposium http://mayocl.in/1QZWfTJ @NINDSnews The post appeared... Mayo Clinic hosts the #BRAINInitiative symposium http://mayocl.in/1QZWfTJ @NINDSnews The post appeared first... περισσότερα »

Acta Biomaterialia

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 23 ώρες
Editorial Board Publication date: November 2015 *Source:*Acta Biomaterialia, Volume 27 2016 Acta Materialia Gold Medal Award Publication date: November 2015 *Source:*Acta Biomaterialia, Volume 27 Substrate topography: A valuable in vitro tool, but a clinical red herring for in vivo tenogenesis Publication date: November 2015 *Source:*Acta Biomaterialia, Volume 27 Author(s): Andrew English, Ayesha Azeem, Kyriakos Spanoudes, Eleanor Jones, Bhawana Tripathi, Nandita Basu, Karrina McNamara, Syed A.M. Tofail, Niall Rooney, Graham Riley, Alan O’Riordan, Graham Cross, Dietmar... περισσότερα »

PLAGA,MSCs,VEGF and BMP-6 induces significantly more bone formation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
Poly(lactic-co-glycolide) polymer constructs cross-linked with human BMP-6 and VEGF protein significantly enhance rat mandible defect repair via Latest Results for Cell/ /and/ /Tissue/ /Research AbstractWe have previously shown that the combined delivery of *mesenchymal stem cells (MSCs), * *vascular endothelial growth factor (VEGF) and * *bone morphogenetic protein 6 (BMP-6)* induces significantly more bone formation than that induced by the delivery of any single factor or a combination of any two factors. We now determine whether the exogenous addition of VEGF and BMP-6 is suffic... περισσότερα »

Ciprofloxacin plus erythromycin or ambroxol

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
Ciprofloxacin plus erythromycin or ambroxol ameliorates endotracheal tube-associated pseudomonas aeruginosa biofilms in a rat model via ScienceDirect Publication: Pathology - Research and Practice Publication date: Available online 19 October 2015 *Source:*Pathology - Research and Practice Author(s): Chen Cheng, Lizhong Du, Jialin Yu, Qi Lu, Yu He, Tao Ran Background and objectivePseudomonas aeruginosa is a multi-drug resistant bacterium, with its biofilm-growing mucoid (alginate-producing) strains being particularly resistant. As atomized drug administration is a common practice in ped...περισσότερα »

GLUT-1 intensity and pattern of expression in thymic epithelial tumors

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
are predictive of WHO subtypes via ScienceDirect Publication: Pathology - Research and Practice Publication date: Available online 19 October 2015 *Source:*Pathology - Research and Practice Author(s): Vincent Thomas-de-Montpréville, Pauline Quilhot, Lara Chalabreysse, Anne De Muret, Véronique Hofman, Sylvie Lantuéjoul, Marie Parrens, Marie-José Payan, Isabelle Rouquette, Véronique Secq, Nicolas Girard, Benjamin Besse, Alexander Marx, Thierry Jo Molina ObjectivesGlucose-transporter-1 (Glut-1) may be a useful marker for differentiating B3 thymomas and thymic carcinomas. Since the literat... περισσότερα »

Video Capture of Plastic Surgery Procedures

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
Using the GoPro HERO 3+ by Graves, Steven Nicholas; Shenaq, Deana Saleh; Langerman, Alexander J.; Song, David H. via Plastic and Reconstructive Surgery – Global Open - Most Popular Articles [image: image]Background: Significant improvements can be made in recoding surgical procedures, particularly in capturing high-quality video recordings from the surgeons’ point of view. This study examined the utility of the GoPro HERO 3+ Black Edition camera for high-definition, point-of-view recordings of plastic and reconstructive surgery. Methods: The GoPro HERO 3+ Black Edition camera was he... περισσότερα »

Urban air pollution by odor sources

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
: Short time prediction Publication date: December 2015 *Source:*Atmospheric Environment, Volume 122 Author(s): Nicola Pettarin, Marina Campolo, Alfredo Soldati A numerical approach is proposed to predict the short time dispersion of odors in the urban environment. The model is based on (i) a three dimensional computational domain describing the urban topography at fine spatial scale (1 m) and on (ii) highly time resolved (1 min frequency) meteorological data used as inflow conditions. The time dependent, three dimensional wind velocity field is reconstructed in the Eulerian framewor...περισσότερα »

Seasonal variation of birch and grass pollen loads and allergen release

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
at two sites in the German Alps Publication date: December 2015 *Source:*Atmospheric Environment, Volume 122 Author(s): Susanne Jochner, Marvin Lüpke, Julia Laube, Ingrid Weichenmeier, Gudrun Pusch, Claudia Traidl-Hoffmann, Carsten Schmidt-Weber, Jeroen T.M. Buters, Annette Menzel Less vegetated mountainous areas may provide better conditions for allergy sufferers. However, atmospheric transport can result in medically relevant pollen loads in such regions. The majority of investigations has focused on the pollen load, expressed as daily averages of pollen per cubic meter of air (p... περισσότερα »

On-bicycle exposure to particulate air pollution

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
: Particle number, black carbon, PM2.5, and particle size Publication date: December 2015 *Source:*Atmospheric Environment, Volume 122 Author(s): Steve Hankey, Julian D. Marshall Inhalation of air pollution during transport is an important exposure pathway, especially for certain modes of travel and types of particles. We measured concentrations of particulate air pollution (particle number [PN], black carbon [BC], fine particles [PM2.5], particle size) using a mobile, bicycle-based monitoring platform during morning and afternoon rush-hour to explore patterns of exposure while cycl...περισσότερα »

International Journal of Rehabilitation Research

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
Quality of statistical reporting in developmental disability journals. Null hypothesis significance testing (NHST) dominates quantitative data analysis, but its use is controversial and has been heavily criticized. The American Psychological Association has advocated the reporting of effect sizes (ES), confidence intervals (CIs), and statistical power analysis to complement NHST results to provide a more comprehensive understanding of research findings. The aim of this paper is to carry out a sample survey of statistical reporting practices in two journals with the highest h5-index s... περισσότερα »

Prevalence and molecular characterization of carbapenemase-producing gram-negative bacteria

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
Prevalence and molecular characterization of carbapenemase-producing gram-negative bacteria from a university hospital in China Yao Sun, Meimei Li, Lijiang Chen, Huale Chen, Xiao Yu, Jianzhong Ye, Yapei Zhang, Chuanling Ma & Tieli Zhou Abstract *Background*: The increasing emergence of carbapenem resistance in gram-negative bacteria associated with carbapenemase prompted the initiation of this study. *Methods*: A total of 3139 gram-negative bacteria were recovered from a 3380-bed university hospital in Wenzhou during 2008 and 2012. Antimicrobial susceptibility was determined...περισσότερα »

Flocked nasal swab versus nasopharyngeal aspirate

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
Flocked nasal swab versus nasopharyngeal aspirate in adult emergency room patients: similar multiplex PCR respiratory pathogen results and patient discomfort Karin B. Hansen, Johan Westin, Lars-Magnus Andersson, Magnus Lindh, Anders Widell & Anna C. Nilsson Abstract Fifty adult emergency room patients with symptoms of respiratory tract infections or acute onset of extreme fatigue were sampled by both nasopharyngeal aspirate (NPA) and flocked nasal swab (fNS). Respiratory agents were detected by a qualitative influenza PCR and an 18-valent multiplex PCR in 20 of 29 patient...περισσότερα »

Comparison of the CAM2A and NAL-NL2 hearing-aid fitting methods

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 ώρες
Comparison of the CAM2A and NAL-NL2 hearing-aid fitting methods for participants with a wide range of hearing losses Brian C. J. Moore & Aleksander Sęk Abstract *Objective*: To compare preferences for sounds processed via a simulated five-channel compression hearing aid fitted using CAM2A and NAL-NL2. *Design*: Within a trial, the same segment of sound was presented twice, once with CAM2A settings and once with NAL-NL2 settings, in random order. The participant indicated which one was preferred and by how much. Stimuli included female and male speech in quiet and four types o... περισσότερα »

Atmospheric Environment

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 23 ώρες
Review: Particle number size distributions from seven major sources and implications for source apportionment studies Publication date: December 2015 *Source:*Atmospheric Environment, Volume 122 Author(s): Tuan V. Vu, Juana Maria Delgado-Saborit, Roy M. Harrison The particle number size distribution (PNSD) of airborne particles not only provides us with information about sources and atmospheric processing of particles, but also plays an important role in determining regional lung dose. As a result, urban particles and their size distributions have received much attention with a rapid...περισσότερα »

Immunopharmacology and Immunotoxicology

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 23 ώρες
Effects of DKK-3, a Wnt signaling inhibitor, on dendritic cell phenotype and T cell polarization Hemn Mohammadpour, Ali Akbar Pourfathollah, Mahin Nikougoftar Zarif & Mohammad Taher Tahoori Pages: 1-7 DOI: 10.3109/08923973.2015.1089274 http://www.tandfonline.com/doi/abs/10.3109/08923973.2015.1089274?ai=1x6b6&ui=843fx&af=T Mechanism of immunoprotective effects of curcumin in DLM-induced thymic apoptosis and altered immune function: an in silico and in vitro study Anoop Kumar, Dinakar Sasmal, Surender Singh Jadav & Neelima Sharma Pages: 1-11 DOI: 10.3109/... περισσότερα »

Neuroimaging Clinics of North America

Alexandros G. SfakianakisστοΑπεικονιστικήΠριν από 1 ημέρα
Imaging of Paranasal Sinuses Publication date: November 2015 *Source:*Neuroimaging Clinics of North America, Volume 25, Issue 4 Author(s): Varsha M. Joshi Copyright Publication date: November 2015 *Source:*Neuroimaging Clinics of North America, Volume 25, Issue 4 CME Accreditation Page Publication date: November 2015 *Source:*Neuroimaging Clinics of North America, Volume 25, Issue 4 Forthcoming/Recent Issues Publication date: November 2015 *Source:*Neuroimaging Clinics of North America, Volume 25, Issue 4 Contributors Publication date: November 2015 *Sourc... περισσότερα »

Computers Informatics Nursing

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ημέρα
Scientific Collaboration in Chinese Nursing Research: A Social Network Analysis Study. Collaboration has become very important in research and in technological progress. Coauthorship networks in different fields have been intensively studied as an important type of collaboration in recent years. Yet there are few published reports about collaboration in the field of nursing. This article aimed to reveal the status and identify the key features of collaboration in the field of nursing in China. Using data from the top 10 nursing journals in China from 2003 to 2013, we constructed a nu... περισσότερα »

European Journal of Anaesthesiology (EJA) - Current Issue

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 1 ημέρα
Is pholcodine a dangerous cough suppressant? No abstract available Combination of dexamethasone and local anaesthetic solution in peripheral nerve blocks: A meta-analysis of randomised controlled trials [image: image]BACKGROUND: Dexamethasone decreases postoperative pain and prolongs the duration of local anaesthetic peripheral nerve blocks in studies including a limited number of patients. OBJECTIVE: The objective of this study is to evaluate the effect of combining dexamethasone with local anaesthetic on sensory and motor peripheral nerve blockade in adults. DESIGN: A systematic rev... περισσότερα »

Indian Journal of Endocrinology and Metabolism

Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ημέρα
Community endocrinology *Sanjay Kalra, Arun Kumar, Sreedevi Aswathy, Vanishree Shriraam* Indian Journal of Endocrinology and Metabolism 2015 19(6):695-697 Green diabetology *Sanjay Kalra, Rajiv Girdhar, Rakesh Sahay* Indian Journal of Endocrinology and Metabolism 2015 19(6):698-700 Gestational diabetes in India: Science and society *Ambrish Mithal, Beena Bansal, Sanjay Kalra* Indian Journal of Endocrinology and Metabolism 2015 19(6):701-704 Efficacy and safety of canagliflozin among patients with type 2 diabetes mellitus: A systematic review and meta-analysis *Kirandeep Kaur, Nishkar... περισσότερα »

Annales de Dermatologie et de Vénéréologie

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ημέρα
Editorial board Publication date: October 2015 *Source:*Annales de Dermatologie et de Vénéréologie, Volume 142, Issue 10 Que faut-il penser de la vascularite urticarienne hypocomplémentémique en 2015 ? Publication date: October 2015 *Source:*Annales de Dermatologie et de Vénéréologie, Volume 142, Issue 10 Author(s): B. Flageul Incidence des cancers cutanés et non cutanés chez les transplantés rénaux afro-caribéens : données guadeloupéennes de 2004 à 2011 Publication date: October 2015 *Source:*Annales de Dermatologie et de Vénéréologie, Volume 142, Issue 10 Author(s): M.... περισσότερα »

MicroRNA-378g enhanced radiosensitivity of NPC cells partially by targeting protein tyrosine phosphatase SHP-1

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
Ting Lin, Fangzheng Zhou, Haibo Zhou, Xiaofen Pan, Ziyi Sun & Gang Peng Abstract *Purpose*: To investigate the influence of microRNA-378g (miR-378g) on radiosensitivity and metastasis of nasopharyngeal carcinoma cells and study how miR-378g regulated Src homology region 2 domain-containing phosphatase-1 (SHP-1) expression. *Materials and methods*: Polymerase chain reaction (PCR) was used to detect the expression level of miR-378g and SHP-1 mRNA in different nasopharyngeal carcinoma (NPC) cell lines. MiR-378g mimics were transfected into NPC cells and radiosensitivity was de... περισσότερα »

Speech production, intelligibility and oromotor function in a group of individuals with Möbius sequence

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
Speech production, intelligibility and oromotor function in seven individuals with Möbius sequence Volume 17, Issue 6, December 2015, pages 537-544 10.3109/17549507.2015.1016108 Lotta Sjögreen Abstract *Purpose*: Möbius sequence is a rare disease characterized by congenital facial and abducent nerve palsy. Other cranial nerves may be affected. Cleft palate, intellectual disability and neuropsychiatric disorders are associated with the diagnosis. The aim was to explore speech production, intelligibility and oromotor function in a group of individuals with Möbius sequence. *Method*: Thr...περισσότερα »

Assessment of oral language skills

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
Tests over time: Evaluating the currency of normative data in a complex multilingual environment Volume 17, Issue 6, December 2015, pages 556-564 10.3109/17549507.2015.1024167 Chris Brebner Abstract *Background*: Assessment of oral language skills is challenging in multilingual environments. With language policies promoting increased use of English and reduction of dialectal varieties of languages, rapid changes in language further confound assessment. *Purpose*: This study explores the currency of normative data on an expressive language screening tool in English for English-Mandarin ...περισσότερα »

The effects of peer-mediated intervention on the responses and initiations of pre-schoolers (aged 4;2–5;1) with Autism Spectrum Disorder (ASD)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
Peer-mediated intervention for pre-schoolers with ASD: Effects on responses and initiations Volume 17, Issue 6, December 2015, pages 565-576 10.3109/17549507.2015.1024166 Esther Katz Abstract *Purpose*: This study investigates the effects of peer-mediated intervention on the responses and initiations of pre-schoolers (aged 4;2–5;1) with Autism Spectrum Disorder (ASD). *Method*: A speech-language pathologist and three early childhood educators trained typically-developing peers to facilitate responses and initiations from three pre-schoolers with ASD during playtime. A multiple baseline...περισσότερα »

Provision of dysphagia services

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
in a developing nation: Infrastructural challenges Volume 17, Issue 6, December 2015, pages 594-604 10.3109/17549507.2015.1026276 Rahayu Mustaffa Kamal Abstract *Purpose*: The purpose of the current study was to explore infrastructure issues that may be barriers to the establishment and improvement of dysphagia services in Malaysia compared to settings with established dysphagia management services (i.e. Queensland, Australia). *Method*: A mixed method design incorporating quantitative and qualitative data was used to increase credibility, validity and comprehensiveness of the results... περισσότερα »

Annales de Chirurgie Plastique Esthétique

Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 1 ημέρα
Poly Implant Prothèse (PIP®) et incidence des complications en reconstruction mammaire : une étude rétrospective contrôlée Publication date: Available online 21 October 2015 *Source:*Annales de Chirurgie Plastique Esthétique Author(s): C. Fenoll, F.M. Leclère, M. Hivelin, M. Atlan, I. Cothier-Savey, L. Lantieri, P. Le Masurier Introduction Le 29 mars 2010, les prothèses de la marque PIP® étaient retirées du marché par l’ANSM. Dans cette étude nous revenons sur notre expérience à propos de l’utilisation des prothèses PIP® en reconstruction mammaire. Nous comparons nos complications à ...περισσότερα »

International Journal of Radiation Biology

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 1 ημέρα
MicroRNA-378g enhanced radiosensitivity of NPC cells partially by targeting protein tyrosine phosphatase SHP-1 Ting Lin, Fangzheng Zhou, Haibo Zhou, Xiaofen Pan, Ziyi Sun & Gang Peng Abstract *Purpose*: To investigate the influence of microRNA-378g (miR-378g) on radiosensitivity and metastasis of nasopharyngeal carcinoma cells and study how miR-378g regulated Src homology region 2 domain-containing phosphatase-1 (SHP-1) expression. *Materials and methods*: Polymerase chain reaction (PCR) was used to detect the expression level of miR-378g and SHP-1 mRNA in different nasopha... περισσότερα »

International Journal of Speech-Language Pathology

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ημέρα
Relationship between social interaction bids and language in late talking children Volume 17, Issue 6, December 2015, pages 527-536 10.3109/17549507.2015.1010579 Jasmina R. Vuksanovic Abstract *Purpose*: The aim of this paper is to explore the relationship between language development and the frequency of social interaction (SI) behaviours during language acquisition in late-talking (LT) children who exhibit delays in expressive vocabulary development but have age-appropriate cognitive skills. *Method*: The research consists of a longitudinal study with a first test followed by two re...περισσότερα »

The comprehension of relative clauses by children with specific language impairment and typical development

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
Morphological cues in the comprehension of relative clauses by Greek children with specific language impairment and typical development: A comparative study Volume 17, Issue 6, December 2015, pages 617-626 10.3109/17549507.2015.1048826 Stavroula Stavrakaki Abstract *Purpose*: This study investigated the effect of morphological case and number marking on the comprehension of relative clauses by Greek children with Specific Language Impairment and Language Age controls. *Method*: An agent selection task and experimental materials consisting of 12 subject and 12 object relative clauses w... περισσότερα »

Journal of Dermatological Treatment

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ημέρα
Factors affecting progression-free survival in non-HIV-related Kaposi sarcoma Fatma Sen, Makbule Tambas, Rumeysa Ciftci, Bahtiyar Toz, Leyla Kilic, Hamza U. Bozbey, Hasan Karanlik, Sidika Kurul, Sezai Vatansever, Ethem N. Oral, Esra K. Saglam, Ahmet Kizir, Pinar Saip & Adnan Aydiner Abstract *Background*: Non-HIV related Kaposi sarcoma (NHKS) is a rare indolent neoplasm which is more common around Mediterranean origin. Data concerning factors that influence progression-free survival (PFS) for NHKS are insufficient. The purpose of present retrospective analysis was to di...περισσότερα »

Scandinavian Journal of Occupational Therapy

Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 1 ημέρα
Identity construction and participation in work: Learning from the experiences of persons with psychiatric disability Lana van Niekerk Abstract *Background*: In this article constructions of identity, occupation, and performance are explored with a particular focus on the interrelatedness of these concepts. Insights were derived from a study in which the influences that impact on the work-lives of people with a psychiatric disability were explored. *Method*: An interpretive biography design was utilised. Data construction took the form of narrative interviews and a combination... περισσότερα »

Journal of Cranio-Maxillofacial Surgery

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ημέρα
Editorial Board Publication date: November 2015 *Source:*Journal of Cranio-Maxillofacial Surgery, Volume 43, Issue 9 Plate removal following orthognathic surgery Publication date: November 2015 *Source:*Journal of Cranio-Maxillofacial Surgery, Volume 43, Issue 9 Author(s): Mhairi Little, Richard Julian Langford, Adam Bhanji, David Farr The objectives of this study are to determine the removal rates of orthognathic plates used during orthognathic surgery at James Cook University Hospital and describe the reasons for plate removal. 202 consecutive orthognathic cases were identif... περισσότερα »

Journal of Dairy Science

Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 1 ημέρα
Interpretive Summaries, November 2015 Publication date: November 2015 *Source:*Journal of Dairy Science, Volume 98, Issue 11 ADSA Member News … Publication date: November 2015 *Source:*Journal of Dairy Science, Volume 98, Issue 11 Letter to the editor: Do coagulase-negative staphylococci have no effect on the milk composition of infected mammary gland? A comment on Tomazi et al. (2015) Publication date: November 2015 *Source:*Journal of Dairy Science, Volume 98, Issue 11 Author(s): Nissim Silanikove, Uzi Merin, Gabriel Leitner Letter to the editor: A response to ... περισσότερα »

Artificial Intelligence in Medicine

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ημέρα
Using Arden Syntax for the creation of a multi-patient surveillance dashboard Publication date: Available online 9 October 2015 *Source:*Artificial Intelligence in Medicine Author(s): Stefan Kraus, Caroline Drescher, Martin Sedlmayr, Ixchel Castellanos, Hans-Ulrich Prokosch, Dennis Toddenroth Objective Most practically deployed Arden-Syntax-based clinical decision support (CDS) modules process data from individual patients. The specification of Arden Syntax, however, would in principle also support multi-patient CDS. The patient data management system (PDMS) at our local intensive c...περισσότερα »

Journal of Environmental Radioactivity

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 1 ημέρα
Atmospheric deposition and riverine load of 90Sr and 137Cs to the Gulf of Gdańsk (southern Baltic Sea) in the period 2005–2011 Publication date: January 2016 *Source:*Journal of Environmental Radioactivity, Volume 151, Part 1 Author(s): Michał Saniewski, Tamara Zalewska In the period 2005–2011 total atmospheric fallout and the riverine input to the Gulf of Gdańsk was 1168.8 GBq of 90Sr and 424.1 GBq 137Cs. The major source of both radionuclides to the Gulf of Gdańsk is the Vistula river; its contribution reached 99.7% in the case of 90Sr and 95.8% regarding 137Cs. The atmospheric loa... περισσότερα »

Clinical Otolaryngology

Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ημέρα
Differential characteristics of pediatric sinusitis who underwent endoscopic sinus surgery: children vs. adolescents Objectives We hypothesized that pediatric chronic sinusitis patients might have various clinical characteristics, depending on age, compared symptoms, physical findings, and clinical features in younger children and older adolescent patients who underwent endoscopic sinus surgery (ESS). Design A retrospective review of medical records. Setting A total of 195 pediatric patients who underwent ESS were enrolled and medical records were reviewed. Participants The subjects ...περισσότερα »

Pigment Cell & Melanoma Research

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ημέρα
- Perturbing resistance: a network perspectiveMitchell P. Levesque, Reinhard Dummer, Niko Beerenwinkel, 2015-10-21 11:20:59 AM Abstract The recent convergence of high-dimensional molecular datasets with small-molecule inhibitor pipelines allows for selective targeting of aberrantly regulated pathways in many cancer types. But intra-tumor heterogeneity, paradoxical activation, intrinsic or acquired therapeutic resistance, and non-linear pathway interactions confound most simple targeting strategies(Widmer et al., 2015). For instance, MAPK signaling is ac... περισσότερα »

Laser ablation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
e management of *oral *potentially malignant disorders PJ Thomson, JA McCaul, F Ridout, IL Hutchison - British Journal of *Oral *and …, 2015 *...* clinicians from *oral* and maxillofacial surgery, *oral* medicine, ear, nose, and throat (*ENT*), and plastic *...* Of the 251 who replied, 178 (71%) were *oral* and maxillofacial surgeons, and 99 *...* or 99%) would always treat severely dysplastic lesions by excision or *laser* ablation, whereas *...* Comparison of 3-D Printing and 5-axis Milling for the Production of Dental e-models from Intra-*oral *Scanning HT Yau, TJ Yang, YK Lin - Co... περισσότερα »

Helicobacter pylori infection

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
*Helicobacter pylori infection *in elderly Chinese patients with type 2 diabetes H He, Y Liu - International Journal of Diabetes in Developing …, 2015 Abstract The relationship between *Helicobacter pylori infection *and diabetes is unclear, especially in elderly people. The aims of this study were to determine the possible relationship between H. pylori infection and type 2 diabetes (T2DM) in elderly subjects. In *...* Co-infection with Helicobacter pylori and Epstein–Barr virus in benign upper digestive diseases: An endoscopic and serologic pilot study GM Buzás, J Konderák - United ... περισσότερα »

The Thyroid

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
International *Thyroid *Congress Short Call Abstracts S Liang, H Fagman, M Nilsson, K Dame, S Cincotta… - *Thyroid*, 2015 *...* *Thyroid*. About This Journal... International *Thyroid* Congress Short Call Abstracts. To cite this article: *Thyroid*. October 2015, 25(S1): A-356-A-383. doi:10.1089/thy.2015.29006. abstracts. Published in Volume: 25 Issue S1: October 14, 2015. *...* The Role of Targeted Therapies or Nonsurgical Treatment B Replaced - Controversies in *Thyroid *Surgery, 2015 *...* *thyroid* cancer, PTC papillary *thyroid* cancer, PR partial response, RAI-R DTC radioiodine *a...περισσότερα »

Thyroid Cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
Papillary *thyroid cancer *in childhood: is parental screening helpful? C Stephenson, O Norlen, A Shun, J Karpelowsky… - ANZ Journal of *Surgery*, 2015 Background Familial non-medullary *thyroid cancer *(FNMTC) mandates family screening with ultrasound; however, the need for screening paediatric *thyroid cancer *with no family history has not been addressed. Methods This study conducted a retrospective cohort *...* [PDF] The Influence of Patient Age on Thyroid Nodule Formation, Multinodularity, and *Thyroid Cancer *Risk N Kwong, M Medici, TE Angell, X Liu, E Marqusee… - The Journal o...περισσότερα »

Hyalinizing clear cell carcinoma (HCCC)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
[PDF] A case of hyalinizing clear cell *carcinoma*, so-called clear cell *carcinoma*, not otherwise specified, of the minor *salivary *glands of the buccal mucosa T Yamanishi, K Kutsuma, K Masuyama 2 Abstract Hyalinizing clear cell *carcinoma *(HCCC), so-called clear cell *carcinoma*, not otherwise specified (CCC (NOS)), of the *salivary *glands is a rare and low-grade malignant tumor. We report a case of HCCC so-called CCC (NOS)(referred to as HCCC) of the minor *...*

Head and neck cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
Anticipation of the Impact of Human Papillomavirus on Clinical Decision Making for the *Head and Neck Cancer *Patient ML Gillison, C Restighini - Hematology/Oncology Clinics of North America, 2015 *...* *tumor* HPV status on survival, has had a profound effect on the *head* *and* *neck* *cancer* (HNC) discipline *...* HR, 0.65; 95% CI, 0.4–1.06) reduction in risk of death from *cancer* when compared *...* higher rates of local-regional control, reduced rates of second primary *tumors*, and reduced *...* Safe dose reduction of steroid pre-medication for docetaxel in *head and neck neo... περισσότερα »

The inferior colliculus.The Phonetic Cerebellum

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
[DOC] Tuning for the rate and duration of frequency modulated sweeps in the inferior colliculus of the big brown bat J Morrison - 2015 *...* The spike count *functions* collapse onto each *other* and show the same pattern of excitation across FM *...* echoes at a faster and faster FM sweep rate, so fastpass cells may *function* as an *...* Neural tuning for sound duration: *role* of inhibitory mechanisms in the inferior colliculus. *...* [PDF] The Phonetic Cerebellum: Cerebellar Involvement in *Speech *Sound Production W Ziegler - THE LINGUISTIC CEREBELLUM *...* human) primate cerebel...περισσότερα »

Inner ear

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
[HTML] Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal*inner ear* JC Burns, MC Kelly, M Hoa, RJ Morell, MW Kelley - Nature Communications, 2015 In the *inner ear*, cochlear and vestibular sensory epithelia utilize grossly similar cell types to transduce different stimuli: sound and acceleration. Each individual sensory epithelium is composed of highly heterogeneous populations of cells based on physiological and *...* Localization of sirtuins (SIRT1-7) in the aged mouse *inner ear* M Takumida, H Takumida, Y Katagiri, M Anniko - Acta Oto-Laryngologi...περισσότερα »

Hearing loss

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ημέρα
[PDF] … Success Post Cochlear Implant be Measured or Defined in Older Adults? Implications of the International Classification of Functioning Brief Core Set for *Hearing Loss* R Alfakir, M Hall, A Holmes - Int J Phys Med Rehabil, 2015 Abstract Objectives: *Hearing loss *(HL) represents a broad category of normal age-related changes that lead to several diminished domains of functions including sensory, cognition, emotional, social, and overall quality of life which may increase loss of independence. *...* Speech Recognition in Noise by Younger and Older Adults Effects of Age, *Hearing...περισσότερα »

Cutaneous Pathology

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ημέρα
- The use of special stains at two dermatopathology laboratories in East AfricaS Kiprono, J Muchunu, H Beltraminelli, 2015-10-21 11:08:30 AM Abstract Background Histopathology is often essential to establish an accurate diagnosis. Pathology laboratories are scarce in most Sub-Saharan Africa where dermatopathology is a developing field. In resource-poor countries, most specimens are analysed only after haematoxylin and eosin staining. The availability of special stains is very limited and restricted to only few centres. The aim of this study is to analyz... περισσότερα »

British Journal of Dermatology

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ημέρα
- Haemangioma in an infant whose mother was receiving long-term propranolol treatment during pregnancyM. Méchineaud, D. Nicaise, L. Martin, 2015-10-21 10:47:14 AM Abstract We read with great interest the article by Ji et al. on the use of propranolol for the treatment of infantile haemangioma (IH).1 IH belongs to a group of benign vascular tumors and is characterized by uncontrolled proliferation of predominantly endothelial cells. Its pathophysiology remains unclear, as well as the precise mechanisms operating in the disappearance of IH with propranol... περισσότερα »

International Journal of Pharmaceutical Investigation

Alexandros G. SfakianakisστοΘεραπείαΠριν από 1 ημέρα
- An overview of viral and nonviral delivery systems for microRNANingning Yang, 2015-10-20 00:00:00 AM *Ningning Yang* International Journal of Pharmaceutical Investigation 2015 5(4):179-181 Διαβάστε περισσότεραΑρχή - Nanostructured lipid carriers: An emerging platform for improving oral bioavailability of lipophilic drugsSaba Khan, 2015-10-20 00:00:00 AM *Saba Khan, Sanjula Baboota, Javed Ali, Sana Khan, Ramandeep Singh Narang, Jasjeet Kaur Narang* International Journal of Pharmaceutical Investigation 2015 5(4):182-191 Nowadays exploration ... περισσότερα »

Microsurgery

Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 1 ημέρα
- Reverse second dorsal metacarpal artery vascularized bone flap for index distal bone loss: A case reportTanya L. Katz, David J. Hunter-Smith, Warren Matthew Rozen, 2015-10-21 10:43:59 AM Fingertip trauma with resultant bony loss is optimally reconstructed with an autologous bone substitute, offering a unique opportunity for use of a local vascularized bone graft. The second dorsal metacarpal artery is well-described for use in soft tissue and bony reconstruction, with recent cadaveric studies suggesting a reverse-flow second dorsal metacarpal artery bon... περισσότερα »

International Forum of Allergy & Rhinology

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 1 ημέρα
- The efficacy assessment of a self-administered immunotherapy protocolFrederick M. Schaffer, Larry M. Garner, Myla Ebeling, Jeffrey M. Adelglass, Thomas C. Hulsey, Andrew R. Naples, 2015-10-21 10:40:30 AM Background We previously reported the safety of a self-administered subcutaneous immunotherapy (SCIT) protocol. Here we report the results of the retrospective efficacy trial of the United Allergy Service (UAS) self-administered SCIT protocol. We hypothesized that by utilizing a slow SCIT buildup phase, designed to attain recommended allergen concentrati... περισσότερα »

Current Opinion in Allergy and Clinical Immunology

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 1 ημέρα
Published Ahead-of-Print - Newborn screening for severe combined immune deficiency (technical and political aspects).Kobrynski, Lisa, 2015-10-17 07:00:00 AM Purpose of review: Newborn screening for severe combined immune deficiency (SCID) has been implemented in more than half of the states in the United States. Despite the success of these programs, numerous challenges remain for implementing newborn screening. The present review will focus on technical, programmatic, and political aspects pertinent to newborn screening for SCID. Recent findings: Recent data ... περισσότερα »

Pediatric Dermatology

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ημέρα
- Impact of a Pediatric Dermatology Service on Emergency Department Utilization for Children with DermatitisBrandon T. Beal, Edward Prodanovic, Jimmy E. Kuo, Eric S. Armbrecht, John R. Peter, Elaine C. Siegfried, 2015-10-21 10:30:24 AM Abstract Background Atopic dermatitis (AD) is the most common chronic pediatric skin disease, and it can profoundly affect a family's quality of life. Children with flaring AD often seek treatment in emergency departments (EDs), which leads to expensive care and ineffective long-term disease control. Objectives The ... περισσότερα »

OtoRhinoLaryngology New Articles & Online Journals,October 21st,2015

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ημέρα
Secondary antibody deficiencies *Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 λεπτό* *Secondary antibody deficiencies.Dhalla, Fatima; Misbah, Siraj A., 2015-10-17 07:00:00 AM Purpose of review: Antibody deficiency can occur in the context of primary immune deficiency due to inherited genetic defects or secondary to a variety of causes. This review aims to summarize current data concerning the causes of secondary antibody deficiency and where possible evidence regarding the use of prophylactic replacement immunoglobulin. Recent findings: Advan... περισσότερα »

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