Detailed Imatinib Metabolite Study in Chronic Myeloid Leukemia

Therapeutic monitoring of drugs is highly useful in individualizing treatment. Imatinib is a chemotherapeutic used in the treatment of chronic myeloid leukemia (CML). Therapeutic monitoring of imatinib and its metabolites results in better clinical outcomes for the patient. However, imatinib metabolization has been poorly studied. With this in mind, Friedecky et al. (2015) used high-resolution mass spectrometry Read the rest of this article

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