Hereditary angioedema: A case report and literature review

Srikant Behera, Lubna Zafar, Asif Hasan

Indian Journal of Allergy, Asthma and Immunology 2015 29(2):92-95

Hereditary angioedema (HAE), also known as Quincke's disease, is an autosomal dominant condition characterized by painless and nonpitting swelling of soft tissues. It is not an allergic phenomenon, as it appears to be on initial examination, thus fails to respond to injectable steroids and adrenaline. The disease may become potentially life threatening due to involvement of airway, thus early suspicion, recognition, and treatment of disease are important. We present here a case of 22-year-old female who developed sudden facial swelling and breathlessness. In the presence of poor response to anti-allergic treatment, past and family history of similar complaints, and low C1 esterase levels, a diagnosis of HAE was made.

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