Gender-Specific Association between Angiotensin II Type 2 Receptor −1332 A/G Gene Polymorphism and Advanced Carotid Atherosclerosis

The angiotensin II type 2 receptor (AT2R) −1332 A/G polymorphism has been denoted as functional and associated with certain cardiovascular disease phenotypes. However, there are no studies considering the association of this gene polymorphism with carotid atherosclerosis (CA) and cerebrovascular events. Therefore, the aim of our study was to investigate a possible association of the AT2R −1332 A/G polymorphism with the occurrence of carotid plaques (CPs) and history of cerebrovascular insult (CVI) in advanced CA.

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