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Τρίτη 26 Ιουλίου 2016

Genetics: Are circRNAs involved in cancer pathogenesis?

Nature Reviews Clinical Oncology. doi:10.1038/nrclinonc.2016.113

Author: Carlo M. Croce

In a paper published recently in Cell, Guarnerio et al. suggest that circular RNAs derived from cancer-associated chromosomal translocations have an oncogenic role; however, the experimental approach that the authors used was inadequate to generate sufficient evidence to prove this role, calling their study into question.



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