Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

Αρχειοθήκη ιστολογίου

! # Ola via Alexandros G.Sfakianakis on Inoreader

Η λίστα ιστολογίων μου

Δευτέρα 5 Δεκεμβρίου 2016

Sleep-related modifications of EEG connectivity in the sensory-motor networks in Huntington Disease: An eLORETA Study and Review of the Literature

S13882457.gif

Publication date: Available online 5 December 2016
Source:Clinical Neurophysiology
Author(s): Carla Piano, Claudio Imperatori, Anna Losurdo, Anna Rita Bentivoglio, Pietro Cortelli, Giacomo Della Marca
ObjectiveTo evaluate EEG functional connectivity in the sensory-motor network, during wake and sleep, in patients with Huntington Disease (HD).Methods23 patients with HD and 23 age- and sex-matched healthy controls were enrolled. EEG connectivity analysis was performed by means of exact Low Resolution Electric Tomography (eLORETA).ResultsIn wake, HD patients showed an increase of delta lagged phase synchronization (T= 3.60; p< 0.05) among Broadman's Areas (BA) 6-8 bilaterally; right BA 6-8 and right BA 1-2-3; left BA 1-2-3 and left BA 4. In NREM, HD patients showed an increase of delta lagged phase synchronization (T= 3.56; p< 0.05) among left BA 1-2-3 and right BA 6-8. In REM, HD patients showed an increase of lagged phase synchronization (T= 3.60; p< 0.05) among the BA 6-8 bilaterally (delta band); left BA 1-2-3 and right BA 1-2-3 (theta); left BA 1-2-3 and right BA 4 (theta); left BA 1-2-3 and right BA 1-2-3 (alpha).ConclusionsOur results may reflect an abnormal function of the motor areas or an effort to counterbalance the pathological motor output. Significance. Our results may help to understand the pathophysiology of sleep-related movement disorders in Huntington's Disease, and to define therapeutically strategies.



http://ift.tt/2gswlN6

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Αρχειοθήκη ιστολογίου