A clitoral verrucous carcinoma in an area of lichen planus has aggressive features.

A clitoral verrucous carcinoma in an area of lichen planus has aggressive features.

World J Surg Oncol. 2017 Jan 06;15(1):7

Authors: Tjalma WA, Siozopoulou V, Huizing MT

Abstract
BACKGROUND: Verrucous carcinoma of the vulva is extremely rare. It is a slow growing, low malignant variant of a squamous cell carcinoma with a cauliflower appearance. Women with lichen planus have an increased risk of developing vulval cancer.
CASE PRESENTATION: A 79-year-old woman consulted for vulval itching. On clinical examination, a 3-cm large verrucous clitoral cancer in an area of lichen planus was seen. Based on her last clinical examination, the growth was estimated to be 1 cm(2) per month with an invasion depth after 6 months of 5 mm. A tumor developing in an area of lichen planus appears to have more aggressive features. This is the first time that the growth of a verrucous carcinoma has been documented in an area of lichen planus.
CONCLUSIONS: Clinicians and patients should be aware of the aggressive behavior of cancers developing in areas of lichen planus and adjust their surgical management together with the follow-up strategy.

PMID: 28061900 [PubMed - in process]

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