Thymoma-associated immunodeficiency: a diagnostic challenge for the clinician.

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Thymoma-associated immunodeficiency: a diagnostic challenge for the clinician.

Asian Cardiovasc Thorac Ann. 2017 Jan 01;:218492316687934

Authors: Narahari NK, Gongati PK, Kakarla B, Nizami MI, Boddula RP, Sattavarapu LR

Abstract
Good's syndrome or thymoma-associated immunodeficiency is a rare clinical entity that is often presumed to be common variable immunodeficiency, due to lack of awareness and recognition of this syndrome. This syndrome more often goes unrecognized if a thymoma is not detected. An appropriate immunological work-up that aids timely diagnosis and adequate therapy with antimicrobials and intravenous immunoglobulins are mandatory to prevent the long-term complications and mortality associated with this syndrome. We present the clinical and immunological profile of a young man with Good's syndrome that was initially presumed to be common variable immunodeficiency.

PMID: 28068785 [PubMed - as supplied by publisher]

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