A Tale of Division and Polarization in the Mammalian Embryo

Publication date: 6 February 2017
Source:Developmental Cell, Volume 40, Issue 3
Author(s): Shankar Srinivas, Tristan Argeo Rodriguez
The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self-organization in development.

Teaser

The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self-organization in development.


http://ift.tt/2lfhED4