[A rare cases of rhabdomyosarcoma of the uterine cervix: about a case and review of the literature].

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[A rare cases of rhabdomyosarcoma of the uterine cervix: about a case and review of the literature].

Pan Afr Med J. 2016;25:166

Authors: Samlali H, Jouhadi H, Attar H, Sahraoui S, Benider A

Abstract
Rhabdomyosarcoma of the uterine cervix is a rare histological type of cervical cancer, occurring commonly in young girls or sexually active women. Given the aggressiveness of the disease, therapeutic strategy is based on the combination of the three treatment modalities (chemotherapy - radiation therapy-surgery). We report the case of a 20-year old patient with rhabdomyosarcoma of the uterine cervix. The patient had a personal history of recurrent genital infections. Patient's first symptom was profuse metrorrhagias associated with the presence of a mass like "a bunch of grapes". Biopsy was in favor of a rhabdomyosarcoma of the uterine cervix. E Extension assessment showed locally advanced mass without metastasis. The patient underwent 5 administrations of VAC chemotherapy, exhibiting tumor regression of 90%. She underwent hysterectomy without adnexal conservation. Then she received postoperative pelvic radiation therapy. At 13-months' follow-up the patient was still in complete remission. Rhabdomyosarcoma of the uterine cervix is a rare tumor that develops most often in young girls. It mainly shows locoregional extension. Treatment is based on surgery including conservative treatment as well as radical treatment associated with perioperative chemotherapy. The role of radiation therapy remains poorly defined.

PMID: 28292128 [PubMed - in process]

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