Correlation of Crtc1/3-Maml2 fusion status, grade and survival in mucoepidermoid carcinoma

Mucoepidermoid carcinoma (MEC) is the most common malignant tumor of the salivary glands. Historically, tumor stage and grade have been important predictors of survival. Treatment for this disease has been primarily surgical, with adjuvant radiation reserved for advanced disease. Overall, survival is favorable in specific cases, particularly in tumors with low grade, early T stage, and absence of nodal disease [1]. Conversely, high grade and advanced stage tumors have worse survival. It is unclear if any genetic factors may play a role in prognosis in these tumors.

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