[Atypical presentation of a breast cancer pituitary metastasis].

[Atypical presentation of a breast cancer pituitary metastasis].

Rev Med Liege. 2016 Jul;71(7-8):332-335

Authors: Langrand-Escure J, Vallard A, Suchaud JP, Diao P, Magné N

Abstract
Pituitary metastasis occur in 1-5 % of patients with cancer. We report the discovery of a unique pituitary metastasis of breast cancer. A 67 years old woman was treated in 2003 for local adenocarcinoma. After bone metastatic relapse in 2008, the patient developed diplopia and diabetes insipidus. An MRI revealed a histologically proven metastatic pituitary nodule. Further explorations revealed failure of multiple endocrine axes. Pituitary metastases are relatively rare, but are probably under-diagnosed in the presence of advanced cancers with impaired general condition. This diagnosis should be considered in the context of cancer patients, with a recent history of diabetes insipidus, especially if the latter is associated with other neurological signs (ophthalmoplegia, cephallagia).

PMID: 28383841 [PubMed - in process]

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