Biologic Therapies for Autoimmune and Connective Tissue Diseases.

Related Articles

Biologic Therapies for Autoimmune and Connective Tissue Diseases.

Immunol Allergy Clin North Am. 2017 May;37(2):283-299

Authors: Wolfe RM, Ang DC

Abstract
Biologic therapy continues to revolutionize the treatment of autoimmune disease, especially in rheumatology as the pathophysiology of both inflammation and autoimmune disease becomes better understood. These therapies are designed to dampen the response of the inflammatory cascades. Although the first biologic therapies were approved many years ago, expanding indications and new agents continue to challenge the traditional treatment strategies for rheumatic diseases. This article reviews the data supporting the current use of biologic therapies, including off-label indications, in a subset of rheumatic diseases including rheumatoid arthritis, lupus, inflammatory myositis, ankylosing spondylitis, psoriatic arthritis, vasculitis, and gout.

PMID: 28366477 [PubMed - in process]

http://ift.tt/2oGDRsh