ESAS and FACT-B in eribulin-treated metastatic breast cancer patients: a multicenter, prospective and observational study.
Future Oncol. 2017 Apr 21;:
Authors: Moscetti L, Mentuccia L, Vici P, Quadrini S, Sperduti I, Pizzuti L, Fabbri MA, Vaccaro A, Saccà MM, Barba M, Sergi D, Zampa G, Gamucci T
Abstract
AIM: Quality of life (QoL) is a critical issue for women with metastatic breast cancer (MBC). Eribulin mesylate represents a novel and active drug for pretreated MBC. Regretfully, few data exploring health-related (HR) QoL are available in unselected populations.
PATIENTS & METHODS: A multicenter prospective observational study was conducted in 50 MBC patients treated with eribulin mesylate, in order to evaluate HRQoL and patients' well-being by using the Edmonton symptoms assessment scale (ESAS) and Functional Assessment of Cancer Therapy-Breast questionnaires.
RESULTS: A significant ESAS score improvement was observed with a 10% median decrease. No differences were revealed for the QoL scores.
CONCLUSION: The analysis of ESAS and Functional Assessment of Cancer Therapy scores showed that eribulin mesylate contributes to preserve QoL in MBC patients.
PMID: 28429617 [PubMed - as supplied by publisher]
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