Comparing the Efficiency of Er,Cr:YSGG Laser and Diode Laser on Human β-defensin-1 and IL-1β Levels During the Treatment of Generalized Aggressive Periodontitis and Chronic Periodontitis.

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Comparing the Efficiency of Er,Cr:YSGG Laser and Diode Laser on Human β-defensin-1 and IL-1β Levels During the Treatment of Generalized Aggressive Periodontitis and Chronic Periodontitis.

J Cosmet Laser Ther. 2017 May 30;:

Authors: Ertugrul AS, Tekin Y, Talmac AC

Abstract
BACKGROUND: The aim of this study is to determine the suitability of the Er,Cr:YSGG and 940±15 nm diode laser for the treatment of generalized aggressive periodontitis and chronic periodontitis by measuring the levels of human β-defensin-1 and IL-1β.
PATIENTS AND METHODS: A total of 26 patients were included in this study. The study was designed as a "split-mouth" experiment. We performed scaling and root planing in the right maxillary quadrant, scaling and root planing+Er,Cr:YSGG laser in the left maxillary quadrant, scaling and root planing+940±15 nm diode laser in the left mandibular quadrant, and only scaling and root planing in the right mandibular quadrant. The presence of human β-defensin- 1 and IL-1β was analyzed with an ELISA.
RESULTS: When the baseline and post-treatment human β-defensin-1 levels and IL-1β levels of the study groups were evaluated, a decrease in human β-defensin-1 and IL-1β were observed in the quadrant where the Er,Cr:YSGG laser was applied in both the generalized aggressive periodontitis group and the chronic periodontitis group.
CONCLUSIONS: The use of the Er,Cr:YSGG laser at non-surgical periodontal treatment decreased both IL-1β and human β-defensin-1 levels. It is likely that Er,Cr:YSGG laser is more suitable for the treatment of generalized aggressive periodontitis and chronic periodontitis.

PMID: 28557642 [PubMed - as supplied by publisher]

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