Diagnosing neuroleukemiosis: Is there a role for 18F-FDG-PET/CT?

Publication date: Available online 4 May 2017
Source:Revista Española de Medicina Nuclear e Imagen Molecular
Author(s): A. Sabaté-Llobera, M. Cortés-Romera, E. Gamundí-Grimalt, J.J. Sánchez-Fernández, L. Rodríguez-Bel, C. Gámez-Cenzano
An imaging case is presented on a patient referred to our department for an ¹⁸F-FDG-PET/CT, as a paraneoplastic syndrome was suspected due to his clinical situation. He had a history of acute myeloid leukemia (AML) treated two years earlier, with sustained complete remission to date. ¹⁸F-FDG-PET/CT findings revealed hypermetabolism in almost all nerve roots, suggesting meningeal spread, consistent with the subsequent MRI findings. Cerebrospinal fluid (CSF) findings confirmed a leptomeningeal reactivation of AML. Although not many studies have evaluated the role of ¹⁸F-FDG-PET/CT in leukemia, it is a noninvasive tool for detecting extramedullary sites of disease and a good imaging alternative for those patients on whom an MRI cannot be performed.



http://ift.tt/2pPh3r8