Treatment of disseminated superficial actinic porokeratosis with oral alitretinoin

Abstract

Disseminated superficial actinic porokeratosis (DSAP), the most common type of porokeratosis, usually presents as large numbers of lesions on sun-exposed skin. Although several treatment options including corticosteroids, keratolytics, 5-fluorouracil, imiquimod, vitamin D3 analogues, cryotherapy, curettage, laser therapy and dermabrasion may be considered, there is no evidence-based standard treatment.^1-2 Patient 1 was a 26-year-old female who presented with a 2-year history of progressive scaly macules on both upper and lower extremities.

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