Targeted Drug Delivery Systems and its Therapeutic Applications in Cancer and related Immune Pathological Conditions.

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Targeted Drug Delivery Systems and its Therapeutic Applications in Cancer and related Immune Pathological Conditions.

Infect Disord Drug Targets. 2017 Jun 05;:

Authors: Afridi S, Iqbal J, Anwar F

Abstract
BACKGROUND: Earlier a century ago, Paul Ehrlich proposed an idea of a drug "magic bullet" that selectively eradicate diseased cells without harming the surrounding normal cells.
OBJECTIVE: Since a lot of progress has been attained in this field to discover new horizons for targeted delivery of drug. As major problem in disease therapy is the severe toxic effects of prescribed drugs on healthy cells. In order to reduce the adverse effects of chemotherapy on healthy tissues, herein, we summaries the use of recent drug delivery systems for targeted therapy.
METHOD: The selective delivery of the drugs to specific diseased cells or tissues is the dream of near future. Ideally, for target drug delivery systems, the system should be made up of a carriers and drugs, were carriers play the role of target delivery of the desired drug.
RESULTS: This issue covers the recent advancement, in modern techniques for targeted drug delivery systems.
RESULTS:
CONCLUSION: It encompasses advances, benefits and limitations in state of art work of targeted drug delivery through hydrogels, microfluidics, nano particles, carbon nanotubes, polymeric micelles, liposomes, lipoprotein based drug carriers and dendrites.

PMID: 28595539 [PubMed - as supplied by publisher]

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