The Risk of Curve Progression and Surgery in African Americans With Adolescent Idiopathic Scoliosis

Publication date: July 2017
Source:Spine Deformity, Volume 5, Issue 4
Author(s): Taylor Lara, Nelson Astur, Tamekia L. Jones, Vinayak Perake, Alice Moisan, William C. Warner, Jeffery R. Sawyer, Derek M. Kelly
Study DesignRetrospective clinical cohort study.ObjectiveTo determine if certain risk factors (age, curve magnitude, skeletal maturity, gender, and curve pattern) traditionally associated with curve progression and surgical intervention in the general population apply equally to African Americans.Summary of Background DataCurrently, information is limited on the role that a patient's race plays in the risk of curve progression of adolescent idiopathic scoliosis (AIS), and existing studies have conflicting results.MethodsRetrospective search of records identified patients who were African American, had been diagnosed with AIS, had a major curve Cobb angle of 10 degrees or more, and had at least two clinical visits with spinal radiographs at least 90 days apart to determine the risk factors for surgical treatment, and 2 years apart to determine the risk factors for curve progression. Patients with a medical condition likely to cause scoliosis were excluded.ResultsOf 738 African American patients with AIS, 223 were assessed for surgical risk factors, and 72 were assessed for curve progression risk factors. Fifty-six (29.17%) had progression of the major coronal curve, and 38 (17.04%) underwent surgery. Age at presentation and curve magnitude at presentation were significant risk factors for surgical intervention. Curve magnitude at presentation was a significant risk factor for curve progression. No significant relationships were found for gender or curve type as they relate to surgical intervention or curve progression.ConclusionAge and curve magnitude at presentation were significantly associated with surgery, as is true in other scoliosis populations. Curve magnitude at presentation was associated with curve progression. In contrast to studies in other populations, however, no significant association was observed between curve progression and age at presentation, curve type, or gender, or between surgery and curve type or gender.Level of EvidenceLevel III, prognostic cohort study.



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