Cilia Control Fat Deposition during Tissue Repair

Publication date: 24 July 2017
Source:Developmental Cell, Volume 42, Issue 2
Author(s): Eusebio Perdiguero, Antonio L. Serrano, Pura Muñoz-Cánoves
Fibro/adipogenic progenitors (FAPs) are emerging as crucial regulators of fibrous and fat deposits during skeletal muscle regeneration. In a recent issue of Cell, Kopinke et al. (2017) report that primary cilia induce the adipogenic fate of FAPs in injured and diseased muscle by restraining Hedgehog signaling.

Teaser

Fibro/adipogenic progenitors (FAPs) are emerging as crucial regulators of fibrous and fat deposits during skeletal muscle regeneration. In a recent issue of Cell, Kopinke et al. (2017) report that primary cilia induce the adipogenic fate of FAPs in injured and diseased muscle by restraining Hedgehog signaling.


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