Long-term toxicities in 10-year survivors of radiation treatment for head and neck cancer

There are approximately 436,000 HNC survivors living in the United States [1] and it is estimated that more than 60,000 new head and neck cancers (HNC) will be diagnosed in the United States in 2016 [2]. Historically, HNC was a disease of the elderly associated with tobacco/ethanol abuse and comorbidity [3]. Due to changing demographics with increasing human papillomavirus (HPV)-associated oropharyngeal cancer [4–6], patients with HNC are generally younger at diagnosis and living longer after treatment than historical expectation.

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