UPAR Targeted Molecular Imaging of Cancers with Small Molecule-Based Probes

Publication date: Available online 22 August 2017
Source:Bioorganic & Medicinal Chemistry
Author(s): Feng Ding, Seng Chen, Wanshu Zhang, Yufeng Tu, Yao Sun
Molecular imaging can allow the non-invasive characterization and measurement of biological and biochemical processes at the molecular and cellular levels in living subjects. The imaging of specific molecular targets that are associated with cancers could allow for the earlier diagnosis and better treatment of diseases. Small molecule-based probes play prominent roles in biomedical research and have high clinical translation ability. Here, with an emphasis on small molecule-based probes, we review some recent developments in biomarkers, imaging techniques and multimodal imaging in molecular imaging and highlight the successful applications for molecular imaging of cancers.

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