Gene-environment interaction between an IL4R variant and school endotoxin exposure contributes to asthma symptoms in inner-city children

Publication date: Available online 21 September 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Peggy S. Lai, Amir H. Massoud, Mingcan Xia, Carter R. Petty, Amparito Cunningham, Talal A. Chatila, Wanda Phipatanakul

Teaser

An interleukin 4 receptor genetic variant (IL4Rα-Q576R) is common in children of African ancestry. There is a gene-environment interaction between this variant, school endotoxin exposure, and asthma symptoms.


http://ift.tt/2xmmnWB