Delayed Diagnosis of a Nasal Type Lymphoma Misdiagnosed as Persistent Sinusitis.

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Delayed Diagnosis of a Nasal Type Lymphoma Misdiagnosed as Persistent Sinusitis.

J Adolesc Young Adult Oncol. 2017 Jun;6(2):381-384

Authors: Celentano A, Mascolo M, Cirillo N, De Rosa G, Mignogna MD

Abstract
Nasal Type T/natural killer (NK)-cell lymphomas are rare clinical entities, highly aggressive with a very poor prognosis. We present a case of a 37-year-old immunocompetent man presenting with deep palatal ulceration and a 3-month history of symptoms, which appear to have been misdiagnosed by physicians. The final diagnosis was achieved by a 15-day diagnostic algorithm, during which time the clinical status of the patient worsened severely. In this article, we also provide a succinct update on the clinical and histopathological findings of Peripheral T/NK-cell lymphomas and propose that symptoms that are consistent with these clinical entities should be considered from the early stages to inform a suitable diagnostic pathway Because of their highly aggressive behavior, we suggest that early therapy of T/NK-cell lymphomas may be started before completing the specific diagnostic investigations.

PMID: 28061034 [PubMed - indexed for MEDLINE]

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