Near-infrared intraoperative imaging during resection of an anterior mediastinal soft tissue sarcoma.

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Near-infrared intraoperative imaging during resection of an anterior mediastinal soft tissue sarcoma.

Mol Clin Oncol. 2018 Jan;8(1):86-88

Authors: Predina JD, Newton AD, Desphande C, Singhal S

Abstract
Sarcomas are rare malignancies that are generally treated with multimodal therapy protocols incorporating complete local resection, chemotherapy and radiation. Unfortunately, even with this aggressive approach, local recurrences are common. Near-infrared intraoperative imaging is a novel technology that provides real-time visual feedback that can improve identification of disease during resection. The presented study describes utilization of a near-infrared agent (indocyanine green) during resection of an anterior mediastinal sarcoma. Real-time fluorescent feedback provided visual information that helped the surgeon during tumor localization, margin assessment and dissection from mediastinal structures. This rapidly evolving technology may prove useful in patients with primary sarcomas arising from other locations or with other mediastinal neoplasms.

PMID: 29387401 [PubMed]

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