Referenced MR Thermometry Using Three-Echo Phase-Based Fat Water Separation Method

Publication date: Available online 2 February 2018
Source:Magnetic Resonance Imaging
Author(s): Lorne W. Hofstetter, Desmond T.B. Yeo, W. Thomas Dixon, Luca Marinelli, Thomas K. Foo
A three-point image reconstruction method for internally referenced MR thermometry was developed. The technique exploits the fact that temperature-induced changes in the water resonance frequency are small relative to the chemical shift difference between water and fat signals. This property enabled the use of small angle approximations to derive an analytic phase-based fat-water separation method for MR thermometry. Ethylene glycol and cream cool-down experiments were performed to validate measurement technique. Over a cool-down temperature range of 20°C, maximum deviation between probe and MR measurement (averaged over 1.3cm³ region surrounding probe) was 0.6^oC and 1.1^oC for ethylene glycol and cream samples, respectively.



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