Application of Gelatin Sponge Impregnated with a Mixture of 3 Drugs to Intraoperative Nerve Root Block to Promote Early Postoperative Recovery of Lumbar Disc Herniation.
World Neurosurg. 2018 Mar 31;:
Authors: Du JP, Hao DJ, Fan Y, Huang YF, Zhang JN, Yuan LH
Abstract
OBJECTIVE: To observe the effect of application of gelatin sponge impregnated a mixture of 3 drugs (GSIAM) to intraoperative nerve root block to promote early postoperative recovery of lumbar disc herniation (LDH).
METHOD: A total of 265 patients with single-level LDH were retrospectively analyzed from January 2013 to October 2017. Patients were divided into intervention group and control group according to whether intraoperative application of GSIAM. All patients underwent unilateral MIS-TLIF surgery. Clinical data such as lying-bed period, postoperative hospital stays, VAS score of low back pain and leg pain, JOA score, postoperative satisfaction questionnaire results, and therapeutic effect were collected.
RESULTS: 136 cases were included in the intervention group. 129 cases were included in the control group. The intervention group had significantly shorter lying-bed period and postoperative hospital stays than the control group (P<0.05). VAS scores of low back pain and leg pain in the intervention group at the postoperative day 1-10 were significantly lower than those in the control group (P<0.05). The JOA score at postoperative day 6 and satisfaction at 72 hours after operation were significantly higher in the intervention group than those in the control group (P<0.05). The clinical effect of the intervention group at postoperative day 6 was significantly better than that of the control group (P<0.05).
CONCLUSIONS: Application of GSIAM to intraoperative nerve root block can significantly promote the early postoperative recovery of LDH, and has great short-term clinical efficacy.
PMID: 29614356 [PubMed - as supplied by publisher]
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