Current Status of the PulseRider in the Treatment of Bifurcation Aneurysms: A Systematic Review.

Related Articles

Current Status of the PulseRider in the Treatment of Bifurcation Aneurysms: A Systematic Review.

World Neurosurg. 2018 Apr 23;:

Authors: Aguilar-Salinas P, Brasiliense LBC, Walter CM, Hanel RA, Dumont TM

Abstract
BACKGROUND: The PulseRider is an innovative stent-like device designed for the treatment of intracranial bifurcation aneurysms. The aim of this study was to assess the current evidence on safety and effectiveness of the PulseRider.
METHODS: A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The following databases were searched: PubMed, Ovid MEDLINE, and Scopus. The search strategy consisted of 'pulserider', 'bifurcation aneurysm', and 'endovascular' in both AND and OR combinations. Studies included were original research articles in peer-reviewed journals. The manuscripts were thoroughly examined for study design, outcomes, and results.
RESULTS: Three studies were identified describing use of the PulseRider device in the treatment of 63 patients with 63 bifurcation aneurysms. We identified 2 multicenter case series and 1 single-arm clinical trial. The majority of aneurysms treated were located at the basilar tip (37, 58.7%). All devices were successfully deployed and there were 5 intraoperative complications (7.9%); including 2 intraoperative aneurysm ruptures, 1 vessel dissection, and 2 thrombus formations. Immediate complete aneurysm occlusion was achieved in 61.9% (39/63) of cases and at the 6-month imaging follow-up: 66.7% (42/63) achieved complete aneurysm occlusion. One recanalization was reported in one of the multicenter case series within the 6-month follow-up.
CONCLUSIONS: The PulseRider is safe and probably effective for the treatment of intracranial bifurcation aneurysms, sometimes not amenable for stent-assisted coiling. However, current evidence is limited to a small sample and short follow-up. In addition, the device has not been compared to other treatment modalities.

PMID: 29698797 [PubMed - as supplied by publisher]

https://ift.tt/2HvmZBR