EMT in Metastasis: Finding the Right Balance

Publication date: 18 June 2018
Source:Developmental Cell, Volume 45, Issue 6
Author(s): Hin Ching Lo, Xiang H.-F. Zhang
The epithelial-to-mesenchymal transition (EMT) is a key driver of cancer metastasis. In this issue of Developmental Cell, Aiello et al. (2018) demonstrate that an EMT mechanism involving protein internalization impacts cell migration, while Reichert et al. (2018) identify epithelial plasticity as a determinant of metastatic organotropism in pancreatic cancer.

Teaser

The epithelial-to-mesenchymal transition (EMT) is a key driver of cancer metastasis. In this issue of Developmental Cell, Aiello et al. (2018) demonstrate that an EMT mechanism involving protein internalization impacts cell migration, while Reichert et al. (2018) identify epithelial plasticity as a determinant of metastatic organotropism in pancreatic cancer.


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