Acquired disorders with depigmentation: A systematic approach to vitiliginoid conditions

Publication date: Available online 17 September 2018

Source: Journal of the American Academy of Dermatology

Author(s): Mohammed D. Saleem, Elias Oussedik, Jennifer J. Schoch, Adam C. Berger, Mauro Picardo

Abstract

Acquired disorders with depigmentation are commonly encountered by dermatologists and present with a wide differential diagnosis. Vitiligo, the most common disorder of acquired depigmentation, is characterized by well-defined depigmented macules and patches. Other conditions, such as chemical leukoderma, can present with similar findings, and are often easily mistaken for vitiligo. Key clinical features can help differentiate between acquired disorders of depigmentation. Part I of this two-part series focuses on conditions with a vitiligo-like phenotype. Early recognition and adequate treatment of these conditions is critical in providing appropriate prognostication and treatment.

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