Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Δευτέρα 24 Φεβρουαρίου 2020

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,

BioMed Research International
 BioMed Research InternationalTanshinone IIA Alleviates CCL2-Induced Leaning memory and Cognition Impairment in Rats: A Potential Therapeutic Approach for HIV-Associated Neurocognitive DisorderChemokine CC motif ligand 2 (CCL2) is one of the most recognized proinflammatory chemokines, and the expression of CCL2 in the cerebrospinal fluid of patients infected with HIV-1 is significantly higher than that of healthy people. As such, it is seen as an important cause of HIV-associated neurocognitive disorder...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:18
Immune and Inflammatory Determinants Underlying Alzheimer's Disease Pathology
Immune and Inflammatory Determinants Underlying Alzheimer's Disease Pathology: AbstractThis study examines the link between peripheral immune changes in perpetuation of the Alzheimer's disease (AD) neuropathology and cognitive deficits. Our research design using human AD patients and rodent model is supported by past evidence from genomic studies. We observed an active immune response against Aβ as indicated by the increased Aβ specific IgG antibody in the serum of AD and patients with mild cognitive...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:15
Pharmaceutics, Vol. 12, Pages 185: Intracellular Delivery of Anti-SMC2 Antibodies against Cancer Stem Cells
Pharmaceutics, Vol. 12, Pages 185: Intracellular Delivery of Anti-SMC2 Antibodies against Cancer Stem Cells: Pharmaceutics, Vol. 12, Pages 185: Intracellular Delivery of Anti-SMC2 Antibodies against Cancer Stem CellsPharmaceutics doi: 10.3390/pharmaceutics12020185Authors: Montero Seras-Franzoso Andrade Martinez-Trucharte Vilar-Hernández Quesada Xandri Arango Abasolo Rafael Schwartz Structural maintenance of chromosomes protein 2 (SMC2) is a central component of the...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:15
BRASH syndrome
BRASH syndrome: A 62-year-old woman with chronic kidney disease stage 4, sleep apnoea on continuous positive airway pressure and recent admission for acute-on-chronic diastolic heart failure presented to emergency room with weakness. She was hypotensive and had symptomatic bradycardia in the 30 s secondary to hyperkalaemia and beta-blockers, raising concern for BRASH syndrome. Antihypertensives were immediately held. Potassium-lowering agents (with calcium gluconate for cardiac stability) were begun,...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:14
Fibromuscular dysplasia presenting with a deep vein thrombosis
Fibromuscular dysplasia presenting with a deep vein thrombosis: A 41-year-old male patient presented with isolated right lower limb swelling. An ultrasound scan showed right external iliac and femoral vein deep vein thrombosis due to extrinsic compression by an aneurysm of the right common iliac artery. Investigations including imaging and a tissue biopsy of right and left femoral arteries confirmed a rare clinical presentation of fibromuscular dysplasia involving iliac, coeliac, renal and pulmonary...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:13
Cardiac amyloidosis presenting with recurrent ischaemic strokes
Cardiac amyloidosis presenting with recurrent ischaemic strokes: A 72-year-old man presented to our service with sudden onset right-sided weakness, aphasia and gaze palsy with diplopia. CT angiogram demonstrated an acute thrombotic occlusion of the distal basilar artery, a basilar infarct and the patient underwent successful thrombectomy. ECG and telemetry demonstrated slow atrial fibrillation (AF). His transthoracic echocardiogram (TTE) showed a reduced ejection fraction of 25% with global hypo-kinesis,...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:13
Hard Palate Mucoperiosteal Transplantation for Defects of the Upper Eyelid: A Pilot Study and Evaluation
Hard Palate Mucoperiosteal Transplantation for Defects of the Upper Eyelid: A Pilot Study and Evaluation: Purpose: To use hard palate mucoperiosteum to reconstruct the upper eyelid wisely and to evaluate its function and outcome.Methods: In this case series, medial or lateral defects of the upper eyelid were reconstructed with a hard palate mucoperiosteum graft and a bandage contact lens to protect the cornea. Slit-lamp examinations, in vivo confocal microscopy, patient surveys, and pathologic examinations...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:12
Primitive Myxoid Mesenchymal Tumor of Infancy in the Orbit: A New Location for a Rare Tumor
Primitive Myxoid Mesenchymal Tumor of Infancy in the Orbit: A New Location for a Rare Tumor: Primitive myxoid mesenchymal tumor of infancy is a rare subtype of sarcoma. With the advent of relevant immunohistochemical and genetic analysis, it was defined by Alaggio et al. in a 2006 case series. Since then, 25 further cases are described in the literature—arising variably from the neck, chest, scalp, abdomen, back, or limbs. Here it is described for the first time arising in the orbit, confirmed by...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:12
Asthma in Pregnancy: Pathophysiology, Diagnosis, Whole-Course Management, and Medication Safety
Asthma in Pregnancy: Pathophysiology, Diagnosis, Whole-Course Management, and Medication Safety: Asthma in pregnancy is a health issue of great concern. Physiological changes and drug compliance during pregnancy can affect asthma control in varying degrees, and the control level of asthma and the side effects of asthma medications are closely related to the adverse perinatal outcomes of mother and fetus. This article provides an update on the available literature regarding the alleviating or aggravating...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:11
Spinal Subdural Abscess following Transforaminal Lumbar Interbody Fusion
Spinal Subdural Abscess following Transforaminal Lumbar Interbody Fusion: Spinal subdural abscesses are rare lesions. We report the case of surgical site infection complicated with meningitis and rapidly progressive spinal subdural abscess caused by P. aeruginosa following transforaminal lumbar interbody fusion (TLIF). A 72-year-old woman was admitted to our hospital complaining of drop foot syndrome and sciatica caused by stenosis of the L5/6 intervertebral foramen accompanied by L5 lumbar vertebral...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:10
Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial Infarction
Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial Infarction: A 66-year-old woman presented to the hospital with a one-month history of shortness of breath, fatigue, and postmenopausal vaginal bleeding and a one-week history of chest pain. This case report discusses the rare synchronous occurrence of two different malignancies in the setting of non-ST segment elevation...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:10
CA
Computed tomography ‐guided biopsy for sub‐centimeter lung nodules: technical success and diagnostic accuracyConclusionsCT ‐guided biopsy is a safe and highly accurate diagnostic method for SCLNs. (Source: The Clinical Respiratory Journal)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.MedWorm Cancer & Oncology Research05:03GSE138894 Imipridone anticancer compounds ectopically activate the ClpP protease...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 09:03
Rehabilitation Protocol for Unilateral Laryngeal and Lingual Paralysis (Tapia Syndrome): Comment About "A Challenging Case of Tapia Syndrome After Total Thyroidectomy" By Ildem Deveci, Mehmet Surmeli, and Reyhan Surmeli
Rehabilitation Protocol for Unilateral Laryngeal and Lingual Paralysis (Tapia Syndrome): Comment About "A Challenging Case of Tapia Syndrome After Total Thyroidectomy" By Ildem Deveci, Mehmet Surmeli, and Reyhan Surmeli: Ear, Nose &Throat Journal, Ahead of Print. Tapia syndrome is a rare complication after surgery, with ipsilateral paralysis of vocal cord and tongue due to extracranial involvement of recurrent laryngeal and hypoglossal nerves. Tapia's case report is extremely interesting for...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:59
Lemierre's syndrome: A calamitous complication of oropharyngeal infection
Lemierre's syndrome: A calamitous complication of oropharyngeal infection: Roopesh Yarappa, Sakshi Gagneja, Sourya Acharya, Shreya GattaniJournal of Head & Neck Physicians and Surgeons 2019 7(2):82-84Lemierre's syndrome is an infectious thrombophlebitis of internal jugular vein (IJV) which occurs rarely, as a complication of oropharyngeal infection. We report an unusual case of a 36-year-old healthy female who presented with high-grade fever with chills, sore throat, and diffuse swelling of the...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:59
Comparing the suppressing effect of dexmedetomidine versus lidocaine in cough during anesthesia emergence: A double-blinded randomized clinical trial
Comparing the suppressing effect of dexmedetomidine versus lidocaine in cough during anesthesia emergence: A double-blinded randomized clinical trial: Sohaila Saidie, Hesameddin Modir, Bijan Yazdi, Esmail Moshiri, Abolfazl MohammadbeigiJournal of Head & Neck Physicians and Surgeons 2019 7(2):62-66Background: Cough, laryngospasm, bronchospasm, and tachycardia are physiological responses during anesthesia emergence (AE) and endotracheal extubation. The study addressed the efficacy of dexmedetomidine...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:59
Surgical excision with the negative margins offers best cure rates for ameloblastoma: A case series and review of literature
Surgical excision with the negative margins offers best cure rates for ameloblastoma: A case series and review of literature: Hitesh R Singhavi, Ameya A Pai, Manish Mair, Sudhir Nair, Deepa Nair, Pankaj ChaturvediJournal of Head & Neck Physicians and Surgeons 2019 7(2):72-78Objectives: The purpose of the study was to report a case series of ameloblastoma treated by radical approach with a negative margin. Study Design: The clinical, demographic, and the histopathological data of 24 biopsy-proven...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:59
Induction chemotherapy in sinonasal malignancies: A review of literature
Induction chemotherapy in sinonasal malignancies: A review of literature: Narayana Subramanian, Filippo Marchi, Andrea Luigi Camillo Carobbio, Francesco Missale, Deepak Balasubramanian, Krishnakumar Thankappan, Subramania IyerJournal of Head & Neck Physicians and Surgeons 2019 7(2):52-61Sinonasal cancers form a distinct subset of head-and-neck tumors. They exhibit varied histologies with different clinical outcomes. These tumors are rare, and there exists no randomized trial identifying the ideal...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:58
An update on medullary carcinoma thyroid
An update on medullary carcinoma thyroid: Mithun Raam, Anish Jacob Cherian, Mazhuvanchary Jacob Paul, Deepak Thomas AbrahamJournal of Head & Neck Physicians and Surgeons 2019 7(2):45-51Medullary thyroid carcinoma is a rare neuroendocrine tumor arising from parafollicular cells of the thyroid gland. It occurs in both hereditary and sporadic forms which are associated with the gain of function mutations in rearranged during transfection proto-oncogene on chromosome 10q11.2. There are various syndromic...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:58
Low survival of advanced laryngeal cancers: Time to change the treatment regime?
Low survival of advanced laryngeal cancers: Time to change the treatment regime?: Sandeep Vijay, Sajith Babu Thavarool, S Manu, Naveen George, Raveena R NairJournal of Head & Neck Physicians and Surgeons 2019 7(2):67-71Background: This study aimed to detect the survival outcome of patients who underwent primary laryngectomy in comparison to the salvage total laryngectomy at our institution. Methodology: A retrospective analysis of patients who underwent laryngectomy in our institution from 2009...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:58
Ocular melanoma: A rare entity
Ocular melanoma: A rare entity: Raj Nagarkar, Sirshendu Roy, Ashvin Wagh, Gauri Kokane, Aditya Adhav, Samadhan PawarJournal of Head & Neck Physicians and Surgeons 2019 7(2):79-81Malignant melanoma of eyeball is a rare entity. The overall incidence of malignant melanoma is 3%–7% per year worldwide. Early detection and meticulous treatment planning and its execution are challenge to surgeons. A 38-year-old male presented with loss of visionin one eye, and after investigating, it turned out to be...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:58
Incubus syndrome in late-onset schizophrenia
Incubus syndrome in late-onset schizophrenia: Yogender Kumar Malik, Sandeep GroverJournal of Geriatric Mental Health 2019 6(2):99-100The term "incubus syndrome" is proposed to describe patients suffering from the delusion that they have been sexually approached at night by an unseen lover. This phenomenon has been rarely described in patients with schizophrenia. However, it is rarely been described in elderly patients with late-onset schizophrenia. In this report, we present a patient with late-onset...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:54
Hyposmia in geriatric depression can be a meningioma
Hyposmia in geriatric depression can be a meningioma: Muruganandam Partheeban, Sundararajan MathivananJournal of Geriatric Mental Health 2019 6(2):104-105Depression in the elderly population can be a manifestation of underlying neurological and systemic disorder. It can be harbinger in many neurological illnesses such as Parkinson's disease and Alzheimer's dementia. It can present as early as 10 years before the onset of clinical neurological signs in dementia. Brain tumors can present with varying...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:54
Omega-3 Index More Predictive Than Cholesterol Levels
Omega-3 Index More Predictive Than Cholesterol Levels: The ketogenic diet is beneficial for many people as it helps with weight control and management and offers protection against a number of health ailments. Approached incorrectly, however, it can actually be harmful.In this short video Dr. Eric Berg warns, "The last thing you want to do is get the benefits of the ketogenic diet but then have deficiencies of omega-3 fatty acids." If you're following a standard ketogenic nutrition plan I recommend...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:53
Chest CT Findings in Patients with Corona Virus Disease 2019 and its Relationship with Clinical Features
Chest CT Findings in Patients with Corona Virus Disease 2019 and its Relationship with Clinical Features: Objectives To investigate the chest computed tomography (CT) findings in patients with confirmed corona virus disease 2019 (COVID-19) and to evaluate its relationship with clinical features.Materials and Methods Study sample consisted of 80 patients diagnosed as COVID-19 from January to February 2020. The chest CT images and clinical data were reviewed and the relationship between them was analyzed.Results...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:53
Application of meticulous anatomy skills with straight bipolar electric coagulation forceps in thyroid surgery].
[Application of meticulous anatomy skills with straight bipolar electric coagulation forceps in thyroid surgery].: Related Articles[Application of meticulous anatomy skills with straight bipolar electric coagulation forceps in thyroid surgery].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Feb 07;55(2):139-143Authors: Zhang SW, An CM, Huang RC, Li XJ, Zhao LF, Xu HY, Hai Y, Wang H, Qiu YYAbstract Objective: To compare the efficacies of the two techniques of "micro-hemostasis and micro-cutting"...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:50
Surgical plus radio(chemo)therapy and non-surgery chemoradiotherapy treatment strategies for advanced hypopharyngeal cancer].
[Meta-analysis of comparison for efficacies between surgical plus radio(chemo)therapy and non-surgery chemoradiotherapy treatment strategies for advanced hypopharyngeal cancer].: Related Articles[Meta-analysis of comparison for efficacies between surgical plus radio(chemo)therapy and non-surgery chemoradiotherapy treatment strategies for advanced hypopharyngeal cancer].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Feb 07;55(2):144-149Authors: Fan JM, Wen SX, Wang BQ, Huangfu H, Zhai XS, Zhao...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:50
Evaluation of medium to long term efficacy of balloon dilation in the treatment of aural fullness as chief complaint].
[Evaluation of medium to long term efficacy of balloon dilation in the treatment of aural fullness as chief complaint].: Related Articles[Evaluation of medium to long term efficacy of balloon dilation in the treatment of aural fullness as chief complaint].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Feb 07;55(2):150-153Authors: Huang WJ, Liang MJ, Liu JH, Wang JB, Wang YJ, Zheng YQAbstract Objective: To discuss the characteristics of symptoms improvement based on the follow-up evaluation...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:49
Clinical characteristics and risk factors analysis of intracranial and extracranial arterial dissection].
[Clinical characteristics and risk factors analysis of intracranial and extracranial arterial dissection].: Related Articles[Clinical characteristics and risk factors analysis of intracranial and extracranial arterial dissection].Zhonghua Yi Xue Za Zhi. 2020 Feb 11;100(5):345-350Authors: Shi YP, Wang YH, Cheng WC, Zhang QM, Xu J, Lian YJAbstract Objective: To compare and analyze the clinical features and potential risk factors of intracranial and extracranial arterial dissection. Methods:...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:49
Aquaporin 1, 3, and 5 Patterns in Salivary Gland Mucoepidermoid Carcinoma: Expression in Surgical Specimens and an In Vitro Pilot Study.
Aquaporin 1, 3, and 5 Patterns in Salivary Gland Mucoepidermoid Carcinoma: Expression in Surgical Specimens and an In Vitro Pilot Study.: Related ArticlesAquaporin 1, 3, and 5 Patterns in Salivary Gland Mucoepidermoid Carcinoma: Expression in Surgical Specimens and an In Vitro Pilot Study.Int J Mol Sci. 2020 Feb 14;21(4):Authors: Stamboni MB, Gomes ÁNM, Souza MM, Oliveira KK, Arruda CFJ, de Paula F, Bettim BB, Marques MM, Kowalski LP, Pinto CAL, Arana-Chavez VE, Lourenço SV, Coutinho-Camillo CMAbstract...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:48
The Importance of Cancer-Associated Fibroblasts in the Pathogenesis of Head and Neck Cancers.
The Importance of Cancer-Associated Fibroblasts in the Pathogenesis of Head and Neck Cancers.: Related ArticlesThe Importance of Cancer-Associated Fibroblasts in the Pathogenesis of Head and Neck Cancers.Klin Onkol. 2020;33(1):39-48Authors: Raudenská M, Svobodová M, Gumulec J, Falk M, Masařík MAbstract BACKGROUND: Despite progress in anticancer therapies, head and neck squamous cell carcinoma (HNSCC) has still a low survival rate. Recent studies have shown that tumour stroma may play an important...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:48
Surufatinib in Chinese patients with locally advanced or metastatic differentiated thyroid cancer and medullary thyroid cancer: A multicenter, open-label, Phase II trial.
Surufatinib in Chinese patients with locally advanced or metastatic differentiated thyroid cancer and medullary thyroid cancer: A multicenter, open-label, Phase II trial.: Related ArticlesSurufatinib in Chinese patients with locally advanced or metastatic differentiated thyroid cancer and medullary thyroid cancer: A multicenter, open-label, Phase II trial.Thyroid. 2020 Feb 19;:Authors: Chen JY, Ji QH, Bai C, Zheng X, Zhang Y, Shi F, Li X, Tang PZ, Xu Z, Huang R, Huang T, Pan Y, Fan S, Zhou J, Su...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:47
Silent infection of B and CD8+T lymphocytes by influenza A virus in children with tonsillar hypertrophy.
Silent infection of B and CD8+T lymphocytes by influenza A virus in children with tonsillar hypertrophy.: Related ArticlesSilent infection of B and CD8+T lymphocytes by influenza A virus in children with tonsillar hypertrophy.J Virol. 2020 Feb 19;:Authors: Castro IA, Jorge DMM, Ferreri LM, Martins RB, Pontelli MC, Jesus BLS, Cardoso RS, Criado MF, Carenzi L, Valera FCP, Tamashiro E, Anselmo-Lima WT, Perez DR, Arruda EAbstract Influenza A (IAV) viruses cause more than two million annual episodes...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:47
The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis.
The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis.: Related ArticlesThe virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis.Oncotarget. 2020 Jan 21;11(3):282-293Authors: Carey RM, Rajasekaran K, Seckar T, Lin X, Wei Z, Tong CCL, Ranasinghe VJ, Newman JG, O'Malley BW, Weinstein GS, Feldman MD, Robertson ESAbstract Oropharyngeal squamous cell carcinoma (OPSCC) represents the most common HPV-related malignancy in the United States with increasing...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:47
Co-expression network-based identification of biomarkers correlated with the lymph node metastasis of patients with head and neck squamous cell carcinoma.
Co-expression network-based identification of biomarkers correlated with the lymph node metastasis of patients with head and neck squamous cell carcinoma.: Related ArticlesCo-expression network-based identification of biomarkers correlated with the lymph node metastasis of patients with head and neck squamous cell carcinoma.Biosci Rep. 2020 Feb 28;40(2):Authors: Jin Y, Qin XAbstract Head and neck squamous cell carcinoma (HNSCC) is ranked as one of the most frequent malignancies worldwide...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:47
Desloratadine Ameliorates Olfactory Disorder and Suppresses AMPA Receptor GluA1 Expression in Allergic Rhinitis Rat.
Desloratadine Ameliorates Olfactory Disorder and Suppresses AMPA Receptor GluA1 Expression in Allergic Rhinitis Rat.: Related ArticlesDesloratadine Ameliorates Olfactory Disorder and Suppresses AMPA Receptor GluA1 Expression in Allergic Rhinitis Rat.Arch Immunol Ther Exp (Warsz). 2020 Feb 19;68(1):6Authors: Li S, Zhang X, Li Z, Jiang X, Zhang N, Zhang J, Huang Y, Zhao H, Jiang Y, Li NAbstract Allergic rhinitis (AR) is an IgE-mediated inflammation which causes olfactory dysfunction. Antihistamines...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:47
Radiographic review of anatomy and pathology of the masticator space: what the emergency radiologist needs to know.
Radiographic review of anatomy and pathology of the masticator space: what the emergency radiologist needs to know.: Related ArticlesRadiographic review of anatomy and pathology of the masticator space: what the emergency radiologist needs to know.Emerg Radiol. 2020 Feb 19;:Authors: Chughtai S, Chughtai KA, Montoya S, Bhatt AAAbstract The differential diagnosis of a masticator space (MS) lesion is broad, owing in part to the multiple structures contained within such a small region. It is...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:46
TLRs and RAGE are elevated in carotid plaques from patients with moderate-to-severe obstructive sleep apnea syndrome.
TLRs and RAGE are elevated in carotid plaques from patients with moderate-to-severe obstructive sleep apnea syndrome.: Related ArticlesTLRs and RAGE are elevated in carotid plaques from patients with moderate-to-severe obstructive sleep apnea syndrome.Sleep Breath. 2020 Feb 20;:Authors: Olejarz W, Głuszko A, Cyran A, Bednarek-Rajewska K, Proczka R, Smith DF, Ishman SL, Migacz E, Kukwa WAbstract BACKGROUND: There is growing evidence that obstructive sleep apnea (OSA) promotes vascular endothelial...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:46
Steroids Inhibit Eosinophil Accumulation and Downregulate Hematopoietic Chemotaxic Prostaglandin D2 Receptor in Aspirin-Exacerbated Respiratory Disease.
Steroids Inhibit Eosinophil Accumulation and Downregulate Hematopoietic Chemotaxic Prostaglandin D2 Receptor in Aspirin-Exacerbated Respiratory Disease.: Steroids Inhibit Eosinophil Accumulation and Downregulate Hematopoietic Chemotaxic Prostaglandin D2 Receptor in Aspirin-Exacerbated Respiratory Disease.Ear Nose Throat J. 2020 Feb 20;:145561320902858Authors: Suzuki N, Ko-Mitamura EP, Inui T, Terada T, Dejima K, Nagata N, Urade Y, Kawata RAbstract BACKGROUND: Aspirin-exacerbated respiratory...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:46
European Position Paper on Rhinosinusitis and Nasal Polyps 2020.
European Position Paper on Rhinosinusitis and Nasal Polyps 2020.: European Position Paper on Rhinosinusitis and Nasal Polyps 2020.Rhinology. 2020 Feb 20;58(Suppl S29):1-464Authors: Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, Toppila-Salmi S, Bernal-Sprekelsen M, Mullol J, Alobid I, Terezinha Anselmo-Lima W, Bachert C, Baroody F, von Buchwald C, Cervin A, Cohen N, Constantinidis J, De Gabory L, Desrosiers M, Diamant Z, Douglas RG, Gevaert PH, Hafner A, Harvey RJ, Joos GF, Kalogjera...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:45
Comparison of acupuncture on specific and non-specific points for the treatment of painful temporomandibular disorders: A randomized controlled trial.
Comparison of acupuncture on specific and non-specific points for the treatment of painful temporomandibular disorders: A randomized controlled trial.: Comparison of acupuncture on specific and non-specific points for the treatment of painful temporomandibular disorders: A randomized controlled trial.J Oral Rehabil. 2020 Feb 20;:Authors: Şen S, Orhan G, Sertel S, Schmitter M, Schindler HJ, Lux CJ, Giannakopoulos NNAbstract BACKGROUND AND OBJECTIVE: The aim of this single-center, two-arm,...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:45
Combination of Sarsasapogenin and Fluticasone attenuates ovalbumin-induced airway inflammation in a mouse asthma model.
Combination of Sarsasapogenin and Fluticasone attenuates ovalbumin-induced airway inflammation in a mouse asthma model.: Related ArticlesCombination of Sarsasapogenin and Fluticasone attenuates ovalbumin-induced airway inflammation in a mouse asthma model.Immunopharmacol Immunotoxicol. 2020 Feb 18;:1-10Authors: Ingawale DK, Mandlik SK, Patel SSAbstract Objective: Asthma is a very common airway inflammatory disease for which the existing drug therapy options are insufficient. In this study,...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:45
New insights into the novel anti-inflammatory mode of action of glucocorticoids.
New insights into the novel anti-inflammatory mode of action of glucocorticoids.: Related ArticlesNew insights into the novel anti-inflammatory mode of action of glucocorticoids.Immunopharmacol Immunotoxicol. 2020 Feb 18;:1-15Authors: Ingawale DK, Mandlik SKAbstract Inflammation is a physiological intrinsic host response to injury meant for removal of noxious stimuli and maintenance of homeostasis. It is a defensive body mechanism that involves immune cells, blood vessels and molecular mediators...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:44
Ketoprofen hypersensibility and idiosyncratic response - a case report.
Ketoprofen hypersensibility and idiosyncratic response - a case report.: Related ArticlesKetoprofen hypersensibility and idiosyncratic response - a case report.Immunopharmacol Immunotoxicol. 2020 Feb 21;:1-4Authors: Araujo MARAbstract Context: Ketoprofen is widely used to remove pain. A steady increase on allergic reactions and photoallergic contact dermatitis related to ketoprofen has been reported when there is topical use. However, there are few documented cases of hypersensitivity when...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:44
Identification of core biomarkers associated with pathogenesis and prognostic outcomes of laryngeal squamous-cell cancer using bioinformatics analysis.
Identification of core biomarkers associated with pathogenesis and prognostic outcomes of laryngeal squamous-cell cancer using bioinformatics analysis.: Related ArticlesIdentification of core biomarkers associated with pathogenesis and prognostic outcomes of laryngeal squamous-cell cancer using bioinformatics analysis.Eur Arch Otorhinolaryngol. 2020 Feb 17;:Authors: Chen W, Liao L, Lai H, Yi X, Wang DAbstract PURPOSE: Despite advances in the treatment of laryngeal squamous-cell carcinoma...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:44
Ultra-high-fidelity virtual reality mastoidectomy simulation training: a randomized, controlled trial.
Ultra-high-fidelity virtual reality mastoidectomy simulation training: a randomized, controlled trial.: Related ArticlesUltra-high-fidelity virtual reality mastoidectomy simulation training: a randomized, controlled trial.Eur Arch Otorhinolaryngol. 2020 Feb 17;:Authors: Frithioff A, Frendø M, Mikkelsen PT, Sørensen MS, Andersen SAWAbstract PURPOSE: Ultra-high-fidelity (UHF) graphics in virtual reality (VR) simulation might improve surgical skill acquisition in temporal bone training. This...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:44
Objectivation of laryngeal electromyography (LEMG) data: turn number vs. qualitative analysis.
Objectivation of laryngeal electromyography (LEMG) data: turn number vs. qualitative analysis.: Related ArticlesObjectivation of laryngeal electromyography (LEMG) data: turn number vs. qualitative analysis.Eur Arch Otorhinolaryngol. 2020 Feb 18;:Authors: Kneisz L, Volk GF, Mayr W, Leonhard M, Pototschnig C, Schneider-Stickler BAbstract PURPOSE: This paper describes a first attempt to quantify LEMG data based on turn number calculation. The results obtained for both healthy and ailing thyroarytenoid...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:44
The relation between dizziness and suspected obstructive sleep apnoea.
The relation between dizziness and suspected obstructive sleep apnoea.: Related ArticlesThe relation between dizziness and suspected obstructive sleep apnoea.Eur Arch Otorhinolaryngol. 2020 Feb 18;:Authors: Maas BDPJ, Bruintjes TD, van der Zaag-Loonen HJ, van Leeuwen RBAbstract PURPOSE: (1) To determine the prevalence of a high risk of obstructive sleep apnoea (OSA) in patients with dizziness. (2) To assess a relation between the risk of OSA and dizziness-related impairment. (3) To determine...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:43
Importance of signal intensity on T1-weighted spin-echo sequence for the diagnosis of chronic cholesteatomatous otitis.
Importance of signal intensity on T1-weighted spin-echo sequence for the diagnosis of chronic cholesteatomatous otitis.: Related ArticlesImportance of signal intensity on T1-weighted spin-echo sequence for the diagnosis of chronic cholesteatomatous otitis.Eur Arch Otorhinolaryngol. 2020 Feb 18;:Authors: Moustin D, Veillon F, Karch-Georges A, Riehm S, Djennaoui I, Charpiot A, Venkatasamy AAbstract OBJECTIVE: The aim of our study was to evaluate the importance of a non-injected T1-weighted...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:43
Superomedial partial arytenoidectomy for voice improvement by correction of posterior glottic insufficiency.
Superomedial partial arytenoidectomy for voice improvement by correction of posterior glottic insufficiency.: Related ArticlesSuperomedial partial arytenoidectomy for voice improvement by correction of posterior glottic insufficiency.Eur Arch Otorhinolaryngol. 2020 Feb 18;:Authors: Mahieu R, Heuveling D, Mahieu HAbstract PURPOSE: Arytenoid resection is a well-known intervention to improve glottic airway. Superomedial partial arytenoidectomy (SPA) can also be used for voice improvement by...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:43
Specific classes of drugs are significantly associated with recurrence: antihypertensive therapy with a singular agent, central nervous system agents, PPIs, vitamin D and thyroid hormones. On the other hand, the lack of correlation between some drugs and recurrence could be linked to the effectiveness of therapy in controlling hypertension, dyslipidaemia and diabetes.
Is drug consumption correlated with benign paroxysmal positional vertigo (BPPV) recurrence?: Related ArticlesIs drug consumption correlated with benign paroxysmal positional vertigo (BPPV) recurrence?Eur Arch Otorhinolaryngol. 2020 Feb 20;:Authors: Picciotti PM, Di Cesare T, Tricarico L, De Corso E, Galli J, Paludetti GAbstract BACKGROUND: Benign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral vertigo and its recurrence is fairly common. Several studies correlated...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:43
Is drug consumption correlated with benign paroxysmal positional vertigo (BPPV) recurrence?
Is drug consumption correlated with benign paroxysmal positional vertigo (BPPV) recurrence?: Related ArticlesIs drug consumption correlated with benign paroxysmal positional vertigo (BPPV) recurrence?Eur Arch Otorhinolaryngol. 2020 Feb 20;:Authors: Picciotti PM, Di Cesare T, Tricarico L, De Corso E, Galli J, Paludetti GAbstract BACKGROUND: Benign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral vertigo and its recurrence is fairly common. Several studies correlated...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:42
Fluorescence patterns of the parathyroid glands during surgery using a fluorescence spectroscopy system.
A novel study for fluorescence patterns of the parathyroid glands during surgery using a fluorescence spectroscopy system.: Related ArticlesA novel study for fluorescence patterns of the parathyroid glands during surgery using a fluorescence spectroscopy system.Eur Arch Otorhinolaryngol. 2020 Feb 20;:Authors: Idogawa H, Sakashita T, Homma AAbstract PURPOSE: Recently it was reported that the parathyroid glands (PGs) emit autofluorescence when exposed to near infrared light, and a technique...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:42
Can be compared obstructive respiratory events during drug induced sleep endoscopy (DISE) and nocturnal polysomnography.
Can be compared obstructive respiratory events during drug induced sleep endoscopy (DISE) and nocturnal polysomnography.: Related ArticlesCan be compared obstructive respiratory events during drug induced sleep endoscopy (DISE) and nocturnal polysomnography.Eur Arch Otorhinolaryngol. 2020 Feb 21;:Authors: Ghorbani J, Adimi Naghan P, Safavi Naeini A, Sadeghi Haghighi KAbstract PURPOSE: Obstructive sleep apnea (OSA) is a collapse of pharynx muscles during sleep that can cause obstruction in...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:41
Dacryolith after a Le Fort I fracture: case report
Dacryolith after a Le Fort I fracture: case report: Publication date: Available online 19 February 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): J.-K. Ku, P.-Y. Yun, Y.-K. Kim, J.H. KimAbstractA dacryolith is a rare finding and can be considered as a complication of a Le Fort I fracture. A case of dacryolith and nasolacrimal duct obstruction after surgery for a Le Fort I fracture is described, and the reasons for and prevention of this condition are discussed.
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:41
Cross-septal returned flap: modified endoscopic technique for bilateral closure of septal perforation
Cross-septal returned flap: modified endoscopic technique for bilateral closure of septal perforation: Publication date: Available online 20 February 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): Y. Rusetsky, Z. Mokoyan, O. Spiranskaya, S. ArutyunyanAbstractEndoscopic approaches for septal perforation closure have achieved a certain popularity. Many of the flaps described provide unilateral closure of the perforation. Thus, complete restoration of the normal multilayer...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:41
Imaging characteristics of the mandible and upper airway in children with Robin sequence and relationship to the treatment strategy
Imaging characteristics of the mandible and upper airway in children with Robin sequence and relationship to the treatment strategy: Publication date: Available online 20 February 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): Z. Mao, N. Zhang, L. Shu, Y. CuiAbstractSome patients with Robin sequence (RS) may respond to conservative therapy, while others require surgery; however, there are currently no objective anatomical criteria to gauge surgical indication. The purpose...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:41
Dental implant placement in alveolar cleft patients: a retrospective comparative study on clinical and aesthetic outcomes
Dental implant placement in alveolar cleft patients: a retrospective comparative study on clinical and aesthetic outcomes: Publication date: Available online 22 February 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): J.M. Alberga, K. Stellingsma, H.J.A. Meijer, H.A. Oostenbrink, A. Vissink, G.M. RaghoebarAbstractThe aim of this retrospective study was to assess the clinical and aesthetic outcomes, and patient satisfaction, following dental implant therapy in cleft patients....
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:40
Effect of different concentrations of commercially available mouthwashes on wound healing following periodontal surgery: a randomized controlled clinical trial
Effect of different concentrations of commercially available mouthwashes on wound healing following periodontal surgery: a randomized controlled clinical trial: AbstractObjectivesThe purpose of this study was to evaluate the effect of chlorhexidine and essential oils containing mouth rinses on oral wound healing after periodontal flap surgery.Materials and methodsEighty subjects participated in the study and were randomly assigned to use water, 0.12% chlorhexidine (CHX), essential oils (EO), 5% CHX,...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:40
Cone-beam computed tomography analysis of cemento-osseous dysplasia-induced changes in adjacent structures in a Brazilian population
Cone-beam computed tomography analysis of cemento-osseous dysplasia-induced changes in adjacent structures in a Brazilian population: AbstractObjectivesTo describe the effects of cemento-osseous dysplasia (COD) on anatomical structures.MethodsCBCT scans were retrospectively selected from a database of individuals who attended an Oral Medicine service. Cases with a confirmed diagnosis of periapical, focal, or florid COD were included. Two oral and maxillofacial radiologists assessed the scans. Frequencies...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:40
Comparison of platelet-rich fibrin (PRF) produced using 3 commercially available centrifuges at both high (~ 700 g) and low (~ 200 g) relative centrifugation forces
Comparison of platelet-rich fibrin (PRF) produced using 3 commercially available centrifuges at both high (~ 700 g) and low (~ 200 g) relative centrifugation forces: AbstractObjectivesPlatelet-rich fibrin (PRF) has gained tremendous momentum in recent years as a natural autologous growth factor derived from blood capable of stimulating tissue regeneration. Owing to its widespread use, many companies have commercialized various centrifugation devices with various proposed protocols. The aim of the...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:40
Optimizing mandibular sagittal split of large maxillomandibular advancements for obstructive sleep apnea: patient and surgical factors
Optimizing mandibular sagittal split of large maxillomandibular advancements for obstructive sleep apnea: patient and surgical factors: AbstractObjectivesMaxillomandibular advancement (MMA) confers consistent and high rates of surgical success for obstructive sleep apnea (OSA). In the era of value-based medicine, identifying factors that affect the stability of rigid fixation and allow rapid return to function are important targets for improvement. The aim of this study was to identify patient and...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:39
Effect of various polymerization protocols on the cytotoxicity of conventional and self-adhesive resin-based luting cements
Effect of various polymerization protocols on the cytotoxicity of conventional and self-adhesive resin-based luting cements: AbstractObjectivesThis study evaluated the cytotoxicity of resin-based luting cements on fibroblast cells using different polymerization protocols.Materials and methodsTwo conventional dual-polymerized (RelyX ARC, VariolinkN) and two self-adhesive resin cements (RelyX Unicem, Multilink Speed) specimens were polymerized using four different polymerization protocols: (a) photo-polymerization...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:39
The effect of Alexander, Gianelly, Roth, and MBT bracket systems on anterior retraction: a 3-dimensional finite element study
The effect of Alexander, Gianelly, Roth, and MBT bracket systems on anterior retraction: a 3-dimensional finite element study: AbstractObjectivesThe aims of this study were to compare the effect of 4 bracket systems including Alexander, Roth, MBT, and Gianelly on upper anterior retraction and to quantify the amount of torque loss ratio in sliding mechanics by help of a 3-dimensional (3D) finite element method.Method and materials3D FEM models were constructed in order to simulate anterior incisor...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:39
Second primary molar hypomineralisation and drugs used during pregnancy and infancy. A systematic review
Second primary molar hypomineralisation and drugs used during pregnancy and infancy. A systematic review: AbstractObjectivesHypomineralised second primary molars (HSPM) are due to idiopathic hypomineralisation that affects from 1- to 4-s primary molars, and its aetiology remains unclear. Our objective was to systematically review studies in which the investigators had studied the association between HSPM and drug use during pregnancy and the first year of life.Materials and methodsA systematic search...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:39
Direct and semi-direct resin composite restorations in non-carious cervical lesions: a randomized clinical study
A 2-year clinical evaluation of direct and semi-direct resin composite restorations in non-carious cervical lesions: a randomized clinical study: AbstractObjectivesThe purpose of this study was to evaluate the 2-year success of resin composite restorations in non-carious cervical lesions (NCCLs) using the direct or semi-direct techniques.Materials and methodsThirty volunteers presenting with at least two NCCLs were included. Each participant received one restoration using the direct technique and...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:38
Bleaching gel mixed with MI Paste Plus reduces penetration of H 2 O 2 and damage to pulp tissue and maintains bleaching effectiveness
Bleaching gel mixed with MI Paste Plus reduces penetration of H 2 O 2 and damage to pulp tissue and maintains bleaching effectiveness: AbstractObjectivesMI Paste Plus remineralizer (Rem) strengthens dental structures after bleaching. We investigated the effect of Rem on the penetration of hydrogen peroxide (H2O2), bleaching effectiveness, and pulp inflammation after bleaching.Materials and methodsBovine disks were grouped as follows (n = 10): control (untreated), bleached (Ble; 35% H2O2, 30 min),...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:38
Treatment of intrabony defects with modified perforated membranes in aggressive periodontitis: a 4-year follow-up of a randomized controlled trial
Treatment of intrabony defects with modified perforated membranes in aggressive periodontitis: a 4-year follow-up of a randomized controlled trial: AbstractObjective(1) To assess long-term outcomes 4 years following guided tissue regeneration (GTR) of intrabony defects in patients diagnosed with aggressive periodontitis (AgP) and (2) to identify predictors of clinical attachment level (CAL) gain and bone/graft density gain.Materials and methodsIn 15 patients, two deep intrabony defects were randomly...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:37
Evaluation of palatal support tissues for placement of orthodontic mini-implants in mouth breathers with high-narrow palates versus nose breathers with normal palates: a retrospective study
Evaluation of palatal support tissues for placement of orthodontic mini-implants in mouth breathers with high-narrow palates versus nose breathers with normal palates: a retrospective study: AbstractObjectivesThe aim of this study was to compare the palatal total support tissues (TSTs) and bone support tissues (BSTs) at 5-mm paramedian section to the midsagittal suture between mouth breathers with high-narrow palates and nose breathers with normal palates and confirm the practicability and limitation...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:37
Free gingival graft and acellular dermal matrix for gingival augmentation: a 15-year clinical study
Free gingival graft and acellular dermal matrix for gingival augmentation: a 15-year clinical study: AbstractObjectivesThis study evaluated clinical outcomes of acellular dermal matrix (ADM) allograft compared with autogenous free gingival graft (FGG) for gingival augmentation after 15 years.Material and methodsTwenty-two patients were originally included and evaluated by de Resende et al. (Clin Oral Investig 23:539–550, 2019), and 12 accepted to participate in this longitudinal evaluation. Clinical...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:37
The effects of intraperitoneal metoprolol administration on healing of bone defects in rat tibia: a pilot study
The effects of intraperitoneal metoprolol administration on healing of bone defects in rat tibia: a pilot study: AbstractObjectivesMetoprolol is a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties, devoid of intrinsic sympathomimetic activity. Various studies have suggested the effect of beta-blockers on bone remodeling. We aimed to investigate whether metoprolol affects bone remodeling by altering anti-inflammatory and pro-inflammatory cytokines.Materials...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:36
The efficacy of supplemental intraseptal and buccal infiltration anesthesia in mandibular molars of patients with symptomatic irreversible pulpitis
The efficacy of supplemental intraseptal and buccal infiltration anesthesia in mandibular molars of patients with symptomatic irreversible pulpitis: AbstractObjectiveThe aim of this randomized clinical trial was to compare the success rate of three different anesthetic techniques in mandibular molars with symptomatic irreversible pulpitis.Materials and methodsNinety patients with symptomatic irreversible pulpitis in mandibular molars randomly received three anesthetic techniques. Group I: an inferior...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:36
Quality of root canal fillings and prevalence of apical radiolucencies
Quality of root canal fillings and prevalence of apical radiolucencies in a German population: a CBCT analysis: AbstractObjectivesThe aim of this study was to determine the frequency and quality of root canal fillings (RCF) and the prevalence of apical radiolucency (AR) in a German population.Material and methodsFive hundred randomly selected full-size CBCT images (Planmeca ProMax 3D, FOV = 8 × 8 cm, voxel size 160 μm or 200 μm) were obtained from German patients (40.6% = ♂; 59.4% = ♀; mean age = 50.21 ± 12.45 years)....
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:36
Fracture resistance of simulated immature roots using Biodentine and fiber post compared with different canal-filling materials under aging conditions
Fracture resistance of simulated immature roots using Biodentine and fiber post compared with different canal-filling materials under aging conditions: AbstractObjectiveThe aim of this study was to evaluate the fracture resistance of simulated immature roots using Biodentine (BD) and fiber post (FP) compared with different root canal-filling materials under aging conditions.Materials and methodsOne hundred and forty maxillary central anterior teeth were randomly divided into seven groups (n = 20/group)....
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:36
Clinicopathologic characteristics of paranasal sinus fungus ball: retrospective, multicenter study in Korea
Clinicopathologic characteristics of paranasal sinus fungus ball: retrospective, multicenter study in Korea: ConclusionFB is commonly encountered in older women with the increased prevalence. FB had a different clinical presentation, radiological findings, and prognosis than CRS. Further studies are needed to understand the pathophysiologic mechanisms underlying the development of FB. (Source: European Archives of Oto-Rhino-Laryngology)
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:35
Effect of voice therapy with or without transcutaneous electrical stimulation on recovery of injured macroscopically intact recurrent laryngeal nerve after thyroid surgery
Effect of voice therapy with or without transcutaneous electrical stimulation on recovery of injured macroscopically intact recurrent laryngeal nerve after thyroid surgery: ConclusionsAdding transcutaneous electrical stimulation to voice therapy provided no beneficial effect on the recovery of vocal fold movement. Therefore, its indications should be re-evaluated; it is questionable whether stimulation should be routinely recommended. (Source: European Archives of Oto-Rhino-Laryngology)
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:35
Fine needle aspiration cytology for parotid neoplasms: risk of malignancy through inconclusive results and lower grade tumors
Fine needle aspiration cytology for parotid neoplasms: risk of malignancy through inconclusive results and lower grade tumors: ConclusionFNAC is an important tool for preoperative assessment of parotid masses, though its sensitivity in detecting malignancy remains poor. "Inconclusive" FNAC results could further jeopardize FNAC accuracy and should elicit resorting to additional tests, especially when a lower grade parotid cancer is suspected. (Source: European Archives of Oto-Rhino-Laryngology)
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:35
Video head impulse test and caloric test in definite M énière's disease
Video head impulse test and caloric test in definite M énière's disease: ConclusionsThe caloric test can detect abnormalities of the vestibular function better than vHIT in all stages of MD. However, the vHIT showed more specificity for the detection of abnormal SCC function. The vHIT test can be used as a screening tool and the caloric test should be considered if a vHIT result is normal. (Source: European Archives of Oto-Rhino-Laryngology)
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:35
Optimised immunofluorescence method on cleared intact Mongolian gerbil cochlea
Optimised immunofluorescence method on cleared intact Mongolian gerbil cochlea: Publication date: Available online 19 February 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): M. Risoud, M. Tardivel, P.-E. Lemesre, N.-X. Bonne, C. VincentAbstractImmunofluorescence on cleared intact cochlea allows detailed analysis of the cochlear ultrastructure, while avoiding the problems of dissection and serial sections. Protocols have been developed for mice and Mongolian gerbils....
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:34
Ethmoidal drug‐eluting stent therapy is not superior to nasal corticosteroid spray in the prevention of endoscopic sinus surgery: results from a randomized, clinical trial
Ethmoidal drug‐eluting stent therapy is not superior to nasal corticosteroid spray in the prevention of endoscopic sinus surgery: results from a randomized, clinical trial: AbstractObjectivesTo evaluate whether an ethmoidal drug‐eluting stent (DES) (the Relieva StratusTM MicroFlow Spacer) could better prevent endoscopic sinus surgery (ESS) than standard non‐invasive therapy using corticosteroid nasal spray in patients suffering from chronic rhinosinusitis (CRS).DesignProspective, randomised clinical...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:34
Surgical Outcomes of Subtotal Parathyroidectomy for Renal Hyperparathyroidism.
Surgical Outcomes of Subtotal Parathyroidectomy for Renal Hyperparathyroidism.: Related ArticlesSurgical Outcomes of Subtotal Parathyroidectomy for Renal Hyperparathyroidism.Clin Exp Otorhinolaryngol. 2020 Feb 21;:Authors: Kim MS, Kim GH, Lee CH, Park JS, Lee JY, Tae KAbstract Objectives: The aim of this study was to evaluate the effectiveness of subtotal parathyroidectomy for patients with renal hyperparathyroidism. Methods: We studied 25 patients with renal hyperparathyroidism who...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:34
Pretreatment Photopenia on 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Scans Predicts Poor Prognosis in Nasopharyngeal Cancer Patients Undergoing Concurrent Chemoradiotherapy.
Pretreatment Photopenia on 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Scans Predicts Poor Prognosis in Nasopharyngeal Cancer Patients Undergoing Concurrent Chemoradiotherapy.: Related ArticlesPretreatment Photopenia on 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Scans Predicts Poor Prognosis in Nasopharyngeal Cancer Patients Undergoing Concurrent Chemoradiotherapy.Clin Exp Otorhinolaryngol. 2020 Feb 21;:Authors: Topkan E, Selek U, Mertsoylu...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:33
Gradenigo's Syndrome with Carotid Septic Stenosis
Gradenigo's Syndrome with Carotid Septic Stenosis: Gradenigo's syndrome was firstly described in 1907 by Giusseppe Gradenigo and is defined as the clinical triad of suppurative otitis media, ipsilateral abducens nerve palsy, and pain in the distribution of the first and the second branches of the trigeminal nerve. Since the advent of antibiotics, the incidence of this potentially life-threatening complication has diminished, but occasional cases still occur. We herein report a pediatric case of otitis...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:33
Needle Tract Seeding of Thyroid Follicular Carcinoma after Fine-Needle Aspiration
Needle Tract Seeding of Thyroid Follicular Carcinoma after Fine-Needle Aspiration: Introduction. Fine-needle aspiration (FNA) biopsies are fundamental procedures in the diagnoses of thyroid tumours. Reports of needle tract tumour seeding, however, question its practice regarding patient safety and potentially jeopardizing its widespread usage. Case Report. We describe a case of a 50-year-old lady with known multinodular goitre, and previous fine-needle aspiration (FNA) biopsies of her thyroid nodules...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:33
The importance of FDG-PET/CT parameters for the assessment of the immune status in advanced HNSCC
The importance of FDG-PET/CT parameters for the assessment of the immune status in advanced HNSCC: Cancer cells secrete large amounts of lactic acid via aerobic glycolysis. We have shown that lactic acid plays an important role as a proinflammatory and immunosuppressive mediator and promotes tumor progression. Fluorine-18 fluorodeoxyglucose (FDG) uptake detected by positron emission tomography/computed tomography (PET/CT) is considered as a good indicator of aerobic glycolysis in cancer. In this...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:32
Coblation versus microdebrider-assisted turbinoplasty for endoscopic inferior turbinates reduction
Coblation versus microdebrider-assisted turbinoplasty for endoscopic inferior turbinates reduction: Publication date: Available online 19 February 2020Source: Auris Nasus LarynxAuthor(s): Sharanjeet Singh, Ramiza Ramza Ramli, Zahiruddin Wan Mohammad, Baharudin AbdullahAbstractObjectivePatients suffering from persistent inferior turbinates hypertrophy refractory to medical treatments require surgical intervention where the main aim is symptomatic relief without any complications. Extraturbinoplasty...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:32
Implementing a flexible endoscopic evaluation of swallowing at elderly care facilities to reveal characteristics of elderly subjects who screened positive for a swallowing disorder
Implementing a flexible endoscopic evaluation of swallowing at elderly care facilities to reveal characteristics of elderly subjects who screened positive for a swallowing disorder: Publication date: Available online 19 February 2020Source: Auris Nasus LarynxAuthor(s): Mitsuyoshi Imaizumi, Toshihiko Suzuki, Masakazu Ikeda, Takashi Matsuzuka, Aya Goto, Koichi OmoriAbstractObjectivesThe risk of aspiration pneumonia has been reported to increase with age, especially in elderly residents of nursing homes....
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:32
Frontal sinusitis associated with orbital decompression for Graves' orbitopathy
Frontal sinusitis associated with orbital decompression for Graves' orbitopathy: Publication date: Available online 20 February 2020Source: Auris Nasus LarynxAuthor(s): Shun Tatehara, Go Inokuchi, Hiroko Takeda, Shunsuke Kuroki, Hisami Fujio, Atsushi Azumi, Ken-ichi NibuAbstractOrbital decompression (OD) for Graves' orbitopathy usually includes removal of orbital medial wall. While OD occasionally cause or worsen chronic sinusitis because of the obstructed sinus drainage by prolapsed orbital fat,...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:32
The importance of FDG-PET/CT parameters for the assessment of the immune status in advanced HNSCC
The importance of FDG-PET/CT parameters for the assessment of the immune status in advanced HNSCC: Publication date: Available online 20 February 2020Source: Auris Nasus LarynxAuthor(s): Toshimitsu Ohashi, Kousuke Terasawa, Mitsuhiro Aoki, Takashi Akazawa, Hirofumi Shibata, Bunya Kuze, Takahiko Asano, Hiroki Kato, Tatsuhiko Miyazaki, Masayuki Matsuo, Norimitsu Inoue, Yatsuji ItoAbstractObjectiveCancer cells secrete large amounts of lactic acid via aerobic glycolysis. We have shown that lactic acid...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:31
Real-time imaging of head and neck squamous cell carcinomas using confocal micro-endoscopy and applicable dye: A preliminary study
Real-time imaging of head and neck squamous cell carcinomas using confocal micro-endoscopy and applicable dye: A preliminary study: Publication date: Available online 20 February 2020Source: Auris Nasus LarynxAuthor(s): Shogo Shinohara, Kazuo Funabiki, Masahiro Kikuchi, Shinji Takebayashi, Kiyomi Hamaguchi, Shigeo Hara, Daisuke Yamashita, Yukihiro Imai, Akira MizoguchiAbstractObjectivesConfocal laser endomicroscopy (CLE) is a technology that enables microscopic visualization of lesions in real-time...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:31
Better defining best-aided condition: The role of hearing aids on cochlear implantation qualification rates
Better defining best-aided condition: The role of hearing aids on cochlear implantation qualification rates: Publication date: Available online 18 February 2020Source: American Journal of OtolaryngologyAuthor(s): Anthony M. Tolisano, Lilly B. Fang, Joe Walter Kutz, Brandon Isaacson, Jacob B. HunterAbstractObjectiveDescribe the effect of hearing aid type used during cochlear implantation evaluation on qualification rates.MethodsConsecutive adult patients at an academic cochlear implant program undergoing...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:31
Determining the optimal osteotomy distance with the fibula free flap in mandibular reconstruction
Determining the optimal osteotomy distance with the fibula free flap in mandibular reconstruction: Publication date: Available online 19 February 2020Source: American Journal of OtolaryngologyAuthor(s): Sean Hashemi, Masafumi Oda, Keita Onoue, Krystyne Basa, Samuel J. Rubin, Osamu Sakai, Andrew Salama, Waleed H. EzzatAbstractObjectiveFibula free tissue transfer is a common and reliable method for mandibular reconstruction. Functional outcomes from this procedure are dependent on the successful union...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:30
Prognostic factors in cochlear implantation in adults: Determining central process integrity
Prognostic factors in cochlear implantation in adults: Determining central process integrity: Publication date: Available online 19 February 2020Source: American Journal of OtolaryngologyAuthor(s): Eleftherios Savvas, Katharina Heslinga, Benedikt Sundermann, Wolfram Schwindt, Christoph Otto Spiekermann, Mario Koopmann, Claudia RudackAbstractThe purpose of this study is to examine various preoperative factors that can play a role in the auditory rehabilitation outcome of cochlear implant (CI) recipients.In...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:30
Virtual septoplasty: a method to predict surgical outcomes for patients with nasal airway obstruction.
Virtual septoplasty: a method to predict surgical outcomes for patients with nasal airway obstruction.: Virtual septoplasty: a method to predict surgical outcomes for patients with nasal airway obstruction.Int J Comput Assist Radiol Surg. 2020 Feb 20;:Authors: Moghaddam MG, Garcia GJM, Frank-Ito DO, Kimbell JS, Rhee JSAbstract PURPOSE: A deviated nasal septum is the most common etiology for nasal airway obstruction (NAO), and septoplasty is the most common surgical procedure performed by...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:29
Dose indicator for CyberKnife Image-Guided Radiation Therapy.
Dose indicator for CyberKnife Image-Guided Radiation Therapy.: Dose indicator for CyberKnife Image-Guided Radiation Therapy.Med Phys. 2020 Feb 20;:Authors: Moeckli R, Baillod A, Gibellieri D, Conrad M, Marsolat F, Schiappacasse L, Jumeau R, Jeanneret-Sozzi W, Bourhis J, Bochud FO, Germond JFAbstract PURPOSE: To calculate dose distributions from CyberKnife Image Guided Radiation Therapy (IGRT) for brain, H&N, lung, and pelvis treatment regions and use them to extract the corresponding...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:29
The Safety and Efficacy of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange for Laryngologic Surgery.
The Safety and Efficacy of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange for Laryngologic Surgery.: The Safety and Efficacy of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange for Laryngologic Surgery.Laryngoscope. 2020 Feb 20;:Authors: Nekhendzy V, Saxena A, Mittal B, Sun E, Sung K, Dewan K, Damrose EJAbstract OBJECTIVES: Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) is an intraoperative ventilatory technique that allows avoidance of...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:27
Readability of Patient-Reported Outcome Measures for Head and Neck Oncology.
Readability of Patient-Reported Outcome Measures for Head and Neck Oncology.: Readability of Patient-Reported Outcome Measures for Head and Neck Oncology.Laryngoscope. 2020 Feb 20;:Authors: Lee SE, Farzal Z, Ebert CS, Zanation AMAbstract OBJECTIVES/HYPOTHESIS: Patient-reported outcome measures (PROMs) are communication tools to help patients convey their disease experience to medical providers and guide management decisions. However, the utility of healthcare outcome measures is dependent...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:26
Feed and Wrap protocol in magnetic resonance imaging scanning of the temporal bone for the evaluation of congenital sensorineural hearing loss.
Evaluating the success of a newly introduced Feed and Wrap protocol in magnetic resonance imaging scanning of the temporal bone for the evaluation of congenital sensorineural hearing loss.: Evaluating the success of a newly introduced Feed and Wrap protocol in magnetic resonance imaging scanning of the temporal bone for the evaluation of congenital sensorineural hearing loss.Int J Pediatr Otorhinolaryngol. 2020 Jan 29;132:109910Authors: Weng W, Reid A, Thompson A, Kuthubutheen JAbstract OBJECTIVES:...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:25
Fistula prophylaxis with muscle-sparing, myofascial pectoralis major lobe in salvage laryngectomy].
[Fistula prophylaxis with muscle-sparing, myofascial pectoralis major lobe in salvage laryngectomy].: [Fistula prophylaxis with muscle-sparing, myofascial pectoralis major lobe in salvage laryngectomy].Laryngorhinootologie. 2020 Feb 20;:Authors: Dejaco D, Rauchenwald T, Steinbichler T, Wolfram D, Morandi E, Appenroth E, Djedovic G, Pierer G, Riechelmann HAbstract BACKGROUND:  In recurrent hypopharyngeal/laryngeal squamous cell carcinoma after radiation salvage-laryngectomy (salvage-LE) represents...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:25
H&N
51.Laryngoscope. 2020 Feb 21. doi: 10.1002/lary.28553. [Epub ahead of print]Ultrasound-Guided Suture Lateralization in Pediatric Bilateral Vocal Fold Immobility.Puricelli MD1, Peterson J1, Kanotra SP1,2.Author informationKEYWORDS:Pediatric; suture lateralization; ultrasound, larynx, bilateral; vocal fold paralysis PMID:32083723DOI:10.1002/lary.28553Similar articlesSelect item 3208372252.Laryngoscope. 2020 Feb 21. doi: 10.1002/lary.28578. [Epub ahead of print]What is the Role of Transoral Thyroidectomy?Chang...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:25
H&N
21.Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jan;34(1):73-78. doi: 10.13201/j.issn.1001-1781.2020.01.018.[Misdiagnosis analysis: 120 patients with nasal extranodal NK/T cell lymphoma in head and neck].[Article in Chinese; Abstract available in Chinese from the publisher]Liu PL1, Cheng ZX1, Lu MP2, Zhang LQ2, Chen HB2.Author informationAbstractObjective:The Clinicopathological characteristics and the reason of misdiagnosis about nasal extranodal NK/T cell lymphoma in head and neck(ENKTL)...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:22
H&N
1.Int J Pediatr Otorhinolaryngol. 2020 Feb 13;133:109944. doi: 10.1016/j.ijporl.2020.109944. [Epub ahead of print]A targeted tracheostomy care educational initiative to augment resuscitation training in the pediatric setting.Mehta K1, Mosha MH2, Kavanagh KR3.Author informationAbstractOBJECTIVE:To implement a surgeon led initiative for tracheostomy education for non-surgical pediatric first responders in the hospital setting and to assess its efficacy.METHODS:A prospective, observational study conducted...
Medicine by Alexandros G. Sfakianakis
Mon Feb 24, 2020 08:17

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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