Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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! # Ola via Alexandros G.Sfakianakis on Inoreader

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Τετάρτη 12 Αυγούστου 2020

 


CAR-NK for tumor immunotherapy: Clinical transformation and future prospects.
Related Articles CAR-NK for tumor immunotherapy: Clinical transformation and future prospects. Cancer Lett. 2020 03 01;472:175-180 Authors: Wang W, Jiang J, Wu C Abstract Recently, the use of chimeric antigen receptor-modified T (CAR-T)-cells in the treatment of hematological tumors has been successful and has become a clinical hotspot in tumor immunotherapy. However, their wide application is limited by inherent risks such as graft-versus-host...
pubmed: future oncology
Wed Aug 12, 2020 13:13
Tisagenlecleucel Model-Based Cellular Kinetic Analysis of Chimeric Antigen Receptor-T Cells.
Related Articles Tisagenlecleucel Model-Based Cellular Kinetic Analysis of Chimeric Antigen Receptor-T Cells. CPT Pharmacometrics Syst Pharmacol. 2019 05;8(5):285-295 Authors: Stein AM, Grupp SA, Levine JE, Laetsch TW, Pulsipher MA, Boyer MW, August KJ, Levine BL, Tomassian L, Shah S, Leung M, Huang PH, Awasthi R, Mueller KT, Wood PA, June CH Abstract Tisagenlecleucel is a chimeric antigen receptor-T cell therapy that facilitates the killing...
pubmed: future oncology
Wed Aug 12, 2020 13:13
Patterns of end-of-life hospital care for patients with non-Hodgkin lymphoma: exploring the landscape.
Related Articles Patterns of end-of-life hospital care for patients with non-Hodgkin lymphoma: exploring the landscape. Leuk Lymphoma. 2019 08;60(8):1908-1916 Authors: Philip J, Collins A, Ritchie D, Le B, Millar J, McLachlan SA, Krishnasamy M, Hudson P, Sundararajan V Abstract Rapid change, treatment responsiveness, and prognostication difficulties present challenges for palliative care integration for hematology patients. This Australian...
pubmed: future oncology
Wed Aug 12, 2020 13:13
Recent advances and future directions in mantle cell lymphoma research: report of the 2018 mantle cell lymphoma consortium workshop.
Related Articles Recent advances and future directions in mantle cell lymphoma research: report of the 2018 mantle cell lymphoma consortium workshop. Leuk Lymphoma. 2019 08;60(8):1853-1865 Authors: Kahl BS, Dreyling M, Gordon LI, Martin P, Quintanilla-Martinez L, Sotomayor EM Abstract Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin lymphoma characterized by the t(11;14) chromosomal translocation. This translocation most often...
pubmed: future oncology
Wed Aug 12, 2020 13:13
A mathematical model of white blood cell dynamics during maintenance therapy of childhood acute lymphoblastic leukemia.
Related Articles A mathematical model of white blood cell dynamics during maintenance therapy of childhood acute lymphoblastic leukemia. Math Med Biol. 2019 12 04;36(4):471-488 Authors: Le TTT, Jost F, Raupach T, Zierk J, Rauh M, Suttorp M, Stanulla M, Metzler M, Sager S Abstract Acute lymphoblastic leukemia is the most common malignancy in childhood and requires prolonged oral maintenance chemotherapy to prevent disease relapse after remission...
pubmed: future oncology
Wed Aug 12, 2020 13:13
Clinicopathological and genomic features of breast mucinous carcinoma.
Clinicopathological and genomic features of breast mucinous carcinoma. Breast. 2020 Aug 06;53:130-137 Authors: Lu K, Wang X, Zhang W, Ye H, Lao L, Zhou X, Yao S, Lv F Abstract INTRODUCTION: Mucinous carcinoma (MC) of the breast is a special histological type of breast cancer. Clinicopathological characteristics and genomic features of MC is not fully understood. MATERIALS AND METHODS: 186,497 primary breast cancer patients from SEER...
pubmed: her2-positive breast...
Wed Aug 12, 2020 13:08
Real-world impact of anti-HER2 therapy-related cardiotoxicity in patients with advanced HER2-positive breast cancer.
Related Articles Real-world impact of anti-HER2 therapy-related cardiotoxicity in patients with advanced HER2-positive breast cancer. Asia Pac J Clin Oncol. 2020 Aug 10;: Authors: Conduit C, de Boer RH, Lok S, Gibbs P, Malik L, Loh Z, Yeo B, Greenberg S, Devitt B, Lombard J, Nottage M, Collins I, Torres J, Nolan M, Nott L Abstract BACKGROUND: Anti-HER2 therapy-related cardiotoxicity is well described in the context of clinical trials, particularly...
pubmed: her2-positive breast...
Wed Aug 12, 2020 13:08
Oncologic Outcomes of Sentinel Lymph Node Surgery After Neoadjuvant Chemotherapy for Node-Positive Breast Cancer.
Related Articles Oncologic Outcomes of Sentinel Lymph Node Surgery After Neoadjuvant Chemotherapy for Node-Positive Breast Cancer. Ann Surg Oncol. 2020 Aug 10;: Authors: Piltin MA, Hoskin TL, Day CN, Davis J, Boughey JC Abstract BACKGROUND: Sentinel lymph node (SLN) surgery after neoadjuvant chemotherapy (NAC) has been well studied. However, outcomes data addressing the oncologic safety of this technique are sparse. This study aimed to evaluate...
pubmed: her2-positive breast...
Wed Aug 12, 2020 13:08
Impact of prior (neo)adjuvant trastuzumab (NAT) exposure on the efficacy of HER2-targeted therapy for metastatic breast cancer.
Related Articles Impact of prior (neo)adjuvant trastuzumab (NAT) exposure on the efficacy of HER2-targeted therapy for metastatic breast cancer. Breast Cancer Res Treat. 2020 Aug 10;: Authors: Kanjanapan Y, Lok SW, Gibbs P, De Boer R, Yeo B, Greenberg S, Barnett F, Knott L, Richardson G, Wong R, Nottage M, Collins IM, Torres J, Lombard J, Johns J, Harold M, Malik L Abstract PURPOSE: Trastuzumab, pertuzumab, and docetaxel are the standard first-line...
pubmed: her2-positive breast...
Wed Aug 12, 2020 13:08
Prevalence of Obstructive Sleep Apnea Risk According to the STOP-BANG Questionnaire in an Oral Surgery Office-Based Anesthesia Patient Population.
Prevalence of Obstructive Sleep Apnea Risk According to the STOP-BANG Questionnaire in an Oral Surgery Office-Based Anesthesia Patient Population. J Oral Maxillofac Surg. 2020 Jul 18;: Authors: Goldberg JM, Silver MI, Johnson MP Abstract PURPOSE: Patients with obstructive sleep apnea (OSA) are at an increased risk for perioperative and postoperative complications after receiving intravenous (IV) sedation or postoperative analgesia. We previously...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
Clinical utility of oximetric parameters to identify a high-risk phenotype of moderate-severe Obstructive Sleep Apnea (OSA).
Related Articles Clinical utility of oximetric parameters to identify a high-risk phenotype of moderate-severe Obstructive Sleep Apnea (OSA). Clin Respir J. 2020 Aug 11;: Authors: Labarca G, Dreyse J, Salas C, Letelier F, Schmidt A, Rivera F, Jorquera J Abstract It is unclear if oximetric parameters, such as total time of SpO2  <90%, (T90), oxygen desaturation index-3% (ODI), minimum SpO2 , are able to describe a high-risk subtype of cardiovascular...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
Therapeutic options for patients with advanced atrial fibrillation: from lifestyle and medication to catheter and surgical ablation.
Related Articles Therapeutic options for patients with advanced atrial fibrillation: from lifestyle and medication to catheter and surgical ablation. Neth Heart J. 2020 Aug;28(Suppl 1):13-18 Authors: Boersma L, Rienstra M, de Groot JR Abstract Atrial fibrillation (AF) is part of a vicious cycle that includes multiple cardiovascular risk factors and comorbidity which can promote atrial remodelling and AF progression. Most AF-related risk factors-hypertension,...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
Which older adults receive sleep medicine specialty care? Predictors of being seen by a board-certified sleep medicine provider.
Related Articles Which older adults receive sleep medicine specialty care? Predictors of being seen by a board-certified sleep medicine provider. J Clin Sleep Med. 2020 Aug 11;: Authors: Wickwire EM, Jobe SL, Parthasarathy S, Collen J, Capaldi VF, Johnson A, Vadlamani A, Levri JM, Scharf SM, Albrecht JS Abstract STUDY OBJECTIVES: To characterize older adult Medicare beneficiaries seen by board-certified sleep medicine providers (BCSMPs) and...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
Effect of adenoids and tonsil tissue on pediatric obstructive sleep apnea severity determined by computational fluid dynamics.
Related Articles Effect of adenoids and tonsil tissue on pediatric obstructive sleep apnea severity determined by computational fluid dynamics. J Clin Sleep Med. 2020 Aug 11;: Authors: Iwasaki T, Sugiyama T, Yanagisawa-Minami A, Oku Y, Yokura A, Yamasaki Y Abstract STUDY OBJECTIVES: Obstructive sleep apnea (OSA) is a respiratory disorder caused by the obstruction of the upper airway during sleep. The most common cause of pediatric OSA is adenotonsillar...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
Impact of the novel coronavirus disease (COVID-19) on treatment adherence and sleep duration in patients with obstructive sleep apnea treated with positive airway pressure.
Related Articles Impact of the novel coronavirus disease (COVID-19) on treatment adherence and sleep duration in patients with obstructive sleep apnea treated with positive airway pressure. J Clin Sleep Med. 2020 Aug 11;: Authors: Batool-Anwar S, Omobomi OS, Quan SF Abstract STUDY OBJECTIVES: The study objective was to examine the effect of COVID-19 on treatment adherence and self-reported sleep duration among patients with Obstructive Sleep...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
Untreated obstructive sleep apnea is associated with increased hospitalization from influenza infection.
Related Articles Untreated obstructive sleep apnea is associated with increased hospitalization from influenza infection. J Clin Sleep Med. 2020 Aug 11;: Authors: Mok EM, Greenough G, Pollack CC Abstract STUDY OBJECTIVES: There is evidence that sleep deprivation or diseases such as obstructive sleep apnea (OSA) that lead to sleep disruption may adversely impact immune system functioning. We hypothesized that individuals who have OSA who did...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
[A man with acute decline in vision and sleep apnoea].
Related Articles [A man with acute decline in vision and sleep apnoea]. Ned Tijdschr Geneeskd. 2020 Jul 23;164: Authors: Tadema S, Pott JWR, Hoogslag-Bienfait MF Abstract BACKGROUND: Non-arteritic anterior ischaemic optic neuropathy (NAION) is the most common acute optic neuropathy in people older than 50 years. CASE DESCRIPTION: A 66-year-old man with hypertension consulted the ophthalmologist because of increasing visual-field loss...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
Reduction of postural nasal resistance following oropharyngeal surgery in patients with moderate-severe obstructive sleep apnea.
Related Articles Reduction of postural nasal resistance following oropharyngeal surgery in patients with moderate-severe obstructive sleep apnea. Rhinology. 2020 Aug 11;: Authors: Huang CC, Cheng PW, Liao LJ, Huang TW Abstract BACKGROUND: Patients with obstructive sleep apnea (OSA) have elevated nasopharyngeal resistances due to increased turbulent airflow. The study aims to investigate the effect of oropharyngeal surgery on nasal resistance...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
miR-126a-3p targets HIF-1α and alleviates obstructive sleep apnea syndrome with hypertension.
Related Articles miR-126a-3p targets HIF-1α and alleviates obstructive sleep apnea syndrome with hypertension. Hum Cell. 2020 Aug 10;: Authors: He L, Liao X, Zhu G, Kuang J Abstract The obstructive sleep apnea syndrome (OSAS) is a common sleep-related breathing disorder and an important cause of refractory hypertension. MicroRNAs (miRNAs) are involved in the development of hypertension, but their role in OSAS with hypertension (OSAS-hypertension)...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea.
Related Articles Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea. Otolaryngol Head Neck Surg. 2020 Aug 11;:194599820947666 Authors: Raposo D, Menezes M, Rito J, Trindade-Soares M, Adónis C, Loureiro HC, Freire F Abstract OBJECTIVE: To describe drug-induced sleep endoscopy (DISE) findings in children with obstructive sleep apnea and to differentiate them between surgically naïve children and children who had adenotonsillectomy...
pubmed: sleep apnea
Wed Aug 12, 2020 13:29
Estimation of Radiological Exposure Levels in a Mining Area Based on 238U, 226Ra, 232Th and 40K Activity Measurements: A Case Study for Beylikova-Sivrihisar Complex Ore Site in Turkey.
Estimation of Radiological Exposure Levels in a Mining Area Based on 238U, 226Ra, 232Th and 40K Activity Measurements: A Case Study for Beylikova-Sivrihisar Complex Ore Site in Turkey. Radiat Prot Dosimetry. 2020 Aug 11;: Authors: Yücel H, Övüç S, Akkaya G, Çakmak Ş Abstract The study estimated the radiological exposure levels in a mining area for miners in the Beylikova-Sivrihisar (Turkey) complex ore site containing 238U, 226Ra and 232Th....
Radiation protection dosimetry
Wed Aug 12, 2020 15:04
Estimation of Thermal Power Plant Workers Exposure to Magnetic Fields and Simulation of Hazard Zones.
Estimation of Thermal Power Plant Workers Exposure to Magnetic Fields and Simulation of Hazard Zones. Radiat Prot Dosimetry. 2020 Aug 11;: Authors: Bagheri Hosseinabadi M, Khanjani N, Ebrahimi MH, Biganeh J Abstract Extremely low-frequency magnetic fields (ELF-MFs) have raised some concerns due to their possible effects on workers' health. In this study ELF-MFs were measured in different units of the thermal power plant based on gridding the...
Radiation protection dosimetry
Wed Aug 12, 2020 15:04
Extraoral and Cbct Dental Exposures in Portugal.
Related Articles Extraoral and Cbct Dental Exposures in Portugal. Radiat Prot Dosimetry. 2020 Aug 11;: Authors: Trindade H, Morais I, Moreira A Abstract Data from dental extraoral and cone beam computed tomography (CBCT) exposures in Portugal (2019) were gathered, and patient doses for standard adult exams were evaluated. In panoramic X-rays, 442 units (34% of the existing licensed units) were tested, with a third quartile value (PKA) of 82 mGy.cm2....
Radiation protection dosimetry
Wed Aug 12, 2020 15:04
Absolute Measurement of 14.57 mev Neutron Fluence Rate Using Proton Recoil Neutron Telescope.
Related Articles Absolute Measurement of 14.57 mev Neutron Fluence Rate Using Proton Recoil Neutron Telescope. Radiat Prot Dosimetry. 2020 Aug 11;: Authors: Ghodke S, Sathian V, Singh Y, Patel T, Santra S Abstract A single stage vacuum-type proton recoil neutron telescope (PRT) was used for accurate measurement of 14.57 MeV neutron fluence rate from an indigenously developed D-T neutron generator at Purnima, BARC. The telescope consists of a...
Radiation protection dosimetry
Wed Aug 12, 2020 15:04
Factors Important in the Selection of a Rhinology/Skull Base Surgery Fellow: A National Survey of Fellowship Directors.
Related Articles Factors Important in the Selection of a Rhinology/Skull Base Surgery Fellow: A National Survey of Fellowship Directors. Am J Rhinol Allergy. 2020 Aug 10;:1945892420948778 Authors: Johnson J, Stathakios J, Chung MT, Engel R, Folbe A Abstract BACKGROUND: The numbers of Rhinology/Skull Base Surgery fellowship programs and applicants have been increasing in recent years. However, little information is currently available with...
rhinol allergy
Wed Aug 12, 2020 13:53
[Proton therapy-a chance in the treatment of tumors of the head and neck and base of skull].
Related Articles [Proton therapy-a chance in the treatment of tumors of the head and neck and base of skull]. HNO. 2020 Aug 11;: Authors: Timmermann B Abstract BACKGROUND: Radiotherapy (RT) is an integral part of the treatment of many tumors located in the vicinity of sensitive organs and structures, including tumors of the head and neck and base of skull in particular. Due to the risk of side effects associated with RT, the use of highly conformal...
Skull Base
Wed Aug 12, 2020 15:15
Facing a Feared Situation: Endoscopic Endonasal Approach for Petroclival Lesions With Internal Carotid Artery Encasement: 2-Dimensional Operative Video.
Related Articles Facing a Feared Situation: Endoscopic Endonasal Approach for Petroclival Lesions With Internal Carotid Artery Encasement: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2020 Aug 11;: Authors: Anania Y, Venteicher AS, Wang EW, Zenonos GA, Snyderman CH, Gardner PA Abstract A 33-yr-old woman presented with diplopia due to partial III and VI cranial nerve palsies, and an magnetic resonance imaging (MRI) showed a left...
Skull Base
Wed Aug 12, 2020 15:15
Mitigation of Aerosols Generated During Rhinologic Surgery: A Pandemic-Era Cadaveric Simulation.
Related Articles Mitigation of Aerosols Generated During Rhinologic Surgery: A Pandemic-Era Cadaveric Simulation. Otolaryngol Head Neck Surg. 2020 Aug 11;:194599820951169 Authors: Sharma D, Ye MJ, Campiti VJ, Rubel KE, Higgins TS, Wu AW, Shipchandler TZ, Sim MW, Burgin SJ, Illing EA, Park JH, Ting JY Abstract OBJECTIVE: After significant restrictions initially due to the COVID-19 pandemic, otolaryngologists have begun resuming normal clinical...
Skull Base
Wed Aug 12, 2020 15:15
Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic.
Related Articles Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic. Otolaryngol Head Neck Surg. 2020 Aug 11;:194599820949802 Authors: Dharmarajan H, Freiser ME, Sim E, Boorgu DSSK, Corcoran TE, Wang EW, Gardner PA, Snyderman CH Abstract OBJECTIVE: To define the aerosol and droplet risks associated with endonasal drilling and to identify mitigation strategies. STUDY DESIGN: Simulation...
Skull Base
Wed Aug 12, 2020 15:15
The nose lid for the endoscopic endonasal procedures during COVID-19 era: technical note.
Related Articles The nose lid for the endoscopic endonasal procedures during COVID-19 era: technical note. Acta Neurochir (Wien). 2020 Aug 11;: Authors: Solari D, Bove I, Esposito F, Cappabianca P, Cavallo LM Abstract BACKGROUND: COVID-19 pandemic has disrupted the global health systems worldwide. According to the tremendous rate of interhuman transmission via aerosols and respiratory droplets, severe measures have been required to contain contagion...
Skull Base
Wed Aug 12, 2020 15:15
Quantitative diagnostic advantages of three-dimensional ultrasound volume imaging for fetal posterior fossa anomalies: Preliminary establishment of a prediction model.
Related Articles Quantitative diagnostic advantages of three-dimensional ultrasound volume imaging for fetal posterior fossa anomalies: Preliminary establishment of a prediction model. Prenat Diagn. 2019 11;39(12):1086-1095 Authors: Sun L, Guo C, Yao L, Zhang T, Wang J, Wang L, Liu Y, Wang K, Wang L, Wu Q Abstract OBJECTIVES: To quantitatively assess prenatal diagnostic performance of three-dimensional ultrasound (3D-US) for posterior fossa...
Skull Base
Wed Aug 12, 2020 15:15
upper respiratory tract infection; +200 new citations
200 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/08/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Upper respiratory tract infection
Wed Aug 12, 2020 17:00
Simultaneous activation of multiple vestibular pathways upon electrical stimulation of semicircular canal afferents.
Related Articles Simultaneous activation of multiple vestibular pathways upon electrical stimulation of semicircular canal afferents. J Neurol. 2020 Aug 10;: Authors: Boutabla A, Cavuscens S, Ranieri M, Crétallaz C, Kingma H, van de Berg R, Guinand N, Pérez Fornos A Abstract BACKGROUND AND PURPOSE: Vestibular implants seem to be a promising treatment for patients suffering from severe bilateral vestibulopathy. To optimize outcomes, we need...
vestibular evoked
Wed Aug 12, 2020 14:39

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