Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Τετάρτη 30 Σεπτεμβρίου 2020

 


Veterinary Sciences, Vol. 7, Pages 147: How Ultrasound Can Be Useful for Staging Chronic Kidney Disease in Dogs: Ultrasound Findings in 855 Cases
Veterinary Sciences, Vol. 7, Pages 147: How Ultrasound Can Be Useful for Staging Chronic Kidney Disease in Dogs: Ultrasound Findings in 855 Cases Veterinary Sciences doi: 10.3390/vetsci7040147 Authors: Francesca Perondi Ilaria Lippi Veronica Marchetti Barbara Bruno Antonio Borrelli Simonetta Citi In patients affected by chronic kidney disease (CKD), some ultrasonographic (US) abnormalities have been shown to correlate better than others with the progression of the disease....
Veterinary Sciences
03:00
Veterinary Sciences, Vol. 7, Pages 146: MicroRNAs as Biomarkers in Canine Osteosarcoma: A New Future?
Veterinary Sciences, Vol. 7, Pages 146: MicroRNAs as Biomarkers in Canine Osteosarcoma: A New Future? Veterinary Sciences doi: 10.3390/vetsci7040146 Authors: Olivia Gourbault Lola Llobat Sarcomas are frequent in dogs and canine species are excellent animal models for studying the human counterpart. However, osteosarcomas are a rare form of sarcoma with high death rates in humans and dogs. miRNAs are small endogenous RNAs that regulate gene expression post-transcriptionally. The discovery...
Veterinary Sciences
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7188: What Drives Households’ Payment for Waste Disposal and Recycling Behaviours? Empirical Evidence from South Africa’s General Household Survey
IJERPH, Vol. 17, Pages 7188: What Drives Households’ Payment for Waste Disposal and Recycling Behaviours? Empirical Evidence from South Africa’s General Household Survey International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197188 Authors: Abiodun Olusola Omotayo Abeeb Babatunde Omotoso Adebola Saidat Daud Adebayo Isaiah Ogunniyi Kehinde Oluseyi Olagunju Safeguarding the environment and its citizens’ health remains one of the key...
International Journal of Environmental Research and Public Health
03:00
IJERPH, Vol. 17, Pages 7187: The Knowledge, Attitude, Practices, and Satisfaction of Non‐Invasive Prenatal Testing among Chinese Pregnant Women under Different Payment Schemes: A Comparative Study
IJERPH, Vol. 17, Pages 7187: The Knowledge, Attitude, Practices, and Satisfaction of Non‐Invasive Prenatal Testing among Chinese Pregnant Women under Different Payment Schemes: A Comparative Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197187 Authors: Wenjun Zhu XiaoXiao Ling Wenru Shang Jiayan Huang Non-invasive prenatal testing (NIPT) for aneuploidy screening has been widely applied across China, and costs can affect Chinese...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7186: Hypoxic Pilates Intervention for Obesity: A Randomized Controlled Trial
IJERPH, Vol. 17, Pages 7186: Hypoxic Pilates Intervention for Obesity: A Randomized Controlled Trial International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197186 Authors: Jung Kim Park Jung Lim This study examined the effect of Pilates training under hypoxia, a novel treatment method, for obesity. Thirty-two Korean women with obesity (age: 34–60 (47.5 ± 7.5) years) were randomly assigned to control (CON; n = 10),...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7183: Bad Air Can Also Kill: Residential Indoor Air Quality and Pollutant Exposure Risk during the COVID-19 Crisis
IJERPH, Vol. 17, Pages 7183: Bad Air Can Also Kill: Residential Indoor Air Quality and Pollutant Exposure Risk during the COVID-19 Crisis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197183 Authors: Samuel Domínguez-Amarillo Jesica Fernández-Agüera Sonia Cesteros-García Roberto Alonso González-Lezcano During the first outbreak of the SARS-CoV-2 pandemic the population, focusing primarily on the risk of infection, was generally inattentive...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7181: Body Composition and a School Day Hydration State among Polish Children—A Cross-Sectional Study
IJERPH, Vol. 17, Pages 7181: Body Composition and a School Day Hydration State among Polish Children—A Cross-Sectional Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197181 Authors: Agnieszka Kozioł-Kozakowska Beata Piórecka Agnieszka Suder Paweł Jagielski Background: Little is known on the relationship between obesity and hydration level in children. To explore the possible association between children’s hydration status...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7180: Bullying and Harassment in Downsized Workplaces: What Can We Learn from the 2008 Icelandic Economic Collapse?
IJERPH, Vol. 17, Pages 7180: Bullying and Harassment in Downsized Workplaces: What Can We Learn from the 2008 Icelandic Economic Collapse? International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197180 Authors: Hjordis Sigursteinsdottir Gudbjorg Linda Rafnsdottir Gudbjorg Andrea Jonsdottir Research shows that bullying is a significant workplace issue. A previous study showed increased sickness-related absences among municipality employees during the...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7184: Prognostic Factors for Staying at Work for Partially Sick-Listed Workers with Subjective Health Complaints: A Prospective Cohort Study.
IJERPH, Vol. 17, Pages 7184: Prognostic Factors for Staying at Work for Partially Sick-Listed Workers with Subjective Health Complaints: A Prospective Cohort Study. International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197184 Authors: Weerdesteijn Schaafsma Bonefaas-Groenewoud Heymans Van der Beek Anema Examination of prognostic factors for staying at work for long-term sick-listed workers with subjective health complaints (SHC) who...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7178: Mind the Gap: Perceived Partner Responsiveness as a Bridge between General and Partner-Specific Attachment Security
IJERPH, Vol. 17, Pages 7178: Mind the Gap: Perceived Partner Responsiveness as a Bridge between General and Partner-Specific Attachment Security International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197178 Authors: TeKisha M. Rice Madoka Kumashiro Ximena B. Arriaga A core idea of attachment theory is that security develops when attachment figures are responsive to a person’s connection needs. Individuals may be more or less secure in different...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7185: Digital Healthy Diet Literacy and Self-Perceived Eating Behavior Change during COVID-19 Pandemic among Undergraduate Nursing and Medical Students: A Rapid Online Survey
IJERPH, Vol. 17, Pages 7185: Digital Healthy Diet Literacy and Self-Perceived Eating Behavior Change during COVID-19 Pandemic among Undergraduate Nursing and Medical Students: A Rapid Online Survey International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197185 Authors: Duong Pham Do Kim Dam Le Nguyen Nguyen Nguyen Le Do Yang Assessing healthy diet literacy and eating behaviors is critical for identifying appropriate...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7182: The Effect of Self-Reported Lactose Intolerance and Dairy Consumption on Bone Mineral Density Among American Hip Arthroplasty Patients: A Cross-Sectional Study
IJERPH, Vol. 17, Pages 7182: The Effect of Self-Reported Lactose Intolerance and Dairy Consumption on Bone Mineral Density Among American Hip Arthroplasty Patients: A Cross-Sectional Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197182 Authors: Hamilton Ojo Adegboye The relationship between osteoporosis and lactose intolerance is unclear. This study aims to evaluate the association between self-reported lactose intolerance and symptom...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7179: A DPSIR-TODIM Model Security Evaluation of China’s Rare Earth Resources
IJERPH, Vol. 17, Pages 7179: A DPSIR-TODIM Model Security Evaluation of China’s Rare Earth Resources International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197179 Authors: Du Wang Lu Li Rare earth is an important strategic mineral resource for national economy and national security. As the largest producer and exporter of rare earth, China’s rare earth industry has problems associated with excessive production, mismatched pricing...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7177: Awareness, Risk Perception, and Stress during the COVID-19 Pandemic in Communities of Tamil Nadu, India
IJERPH, Vol. 17, Pages 7177: Awareness, Risk Perception, and Stress during the COVID-19 Pandemic in Communities of Tamil Nadu, India International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197177 Authors: Kuang Ashraf Das Bicchieri The health and economic consequences of the COVID-19 pandemic is expected to disproportionately impact residents of lower-middle income countries. Understanding the psychological impact of the pandemic is important...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7173: Herlyn-Werner-Wunderlich Syndrome: Comparison of Two Cases
IJERPH, Vol. 17, Pages 7173: Herlyn-Werner-Wunderlich Syndrome: Comparison of Two Cases International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197173 Authors: Mateusz Kozłowski Katarzyna Nowak Dominika Boboryko Sebastian Kwiatkowski Aneta Cymbaluk-Płoska Background: Herlyn-Werner-Wunderlich Syndrome is a rare malformation syndrome characterized by uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis. Symptoms appear most...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7170: The Adoption of Preventive Behaviors during the COVID-19 Pandemic in China and Israel
IJERPH, Vol. 17, Pages 7170: The Adoption of Preventive Behaviors during the COVID-19 Pandemic in China and Israel International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197170 Authors: Xue-Jing Liu Gustavo S. Mesch The COVID-19 pandemic represents a massive global health crisis. The rapid transmission rate of the virus, as well as the lack of effective medications and vaccines, has posed serious challenges to controlling the spread of the disease....
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7171: The Relationship between Leisure-Time Sedentary Behaviors and Metabolic Risks in Middle-Aged Chinese Women
IJERPH, Vol. 17, Pages 7171: The Relationship between Leisure-Time Sedentary Behaviors and Metabolic Risks in Middle-Aged Chinese Women International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197171 Authors: Jing Fan Caicui Ding Weiyan Gong Fan Yuan Yanning Ma Ganyu Feng Chao Song Ailing Liu The prevalence of metabolic diseases has increased over the past few decades, and epidemiological studies suggest that metabolic diseases may be...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7175: Hospital and Population-Based Evidence for COVID-19 Early Circulation in the East of France
IJERPH, Vol. 17, Pages 7175: Hospital and Population-Based Evidence for COVID-19 Early Circulation in the East of France International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197175 Authors: Gerbaud Guiguet-Auclair Breysse Odoul Ouchchane Peterschmitt Dezfouli-Desfer Breton Background: Understanding SARS-CoV-2 dynamics and transmission is a serious issue. Its propagation needs to be modeled and controlled. The Alsace region...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7176: Impacts of a Care Robotics Project on Finnish Home Care Workers’ Attitudes towards Robots
IJERPH, Vol. 17, Pages 7176: Impacts of a Care Robotics Project on Finnish Home Care Workers’ Attitudes towards Robots International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197176 Authors: Teemu Rantanen Teppo Leppälahti Jaakko Porokuokka Sari Heikkinen Technological advances in elderly care have been rapid, and the introduction of robots in care will be a topical issue in the near future. There has been little research into the possibility of...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7172: Acute and Chronic Catabolic Responses to CrossFit® and Resistance Training in Young Males
IJERPH, Vol. 17, Pages 7172: Acute and Chronic Catabolic Responses to CrossFit® and Resistance Training in Young Males International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197172 Authors: Emanuela Faelli Ambra Bisio Roberto Codella Vittoria Ferrando Luisa Perasso Marco Panascì Daniele Saverino Piero Ruggeri Given the wide variety of conditioning program trainings employed, the present study compared the catabolic effects induced...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7174: Association between Migrant Women’s Legal Status and Prenatal Care Utilization in the PreCARE Cohort
IJERPH, Vol. 17, Pages 7174: Association between Migrant Women’s Legal Status and Prenatal Care Utilization in the PreCARE Cohort International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197174 Authors: Eslier Deneux-Tharaux Sauvegrain Schmitz Luton Mandelbrot Estellat Azria Barriers to access to prenatal care may partially explain the higher risk of adverse pregnancy outcomes among migrants compared with native-born women in...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7168: Assessing the Accessibility of Home-Based Healthcare Services for the Elderly: A Case from Shaanxi Province, China
IJERPH, Vol. 17, Pages 7168: Assessing the Accessibility of Home-Based Healthcare Services for the Elderly: A Case from Shaanxi Province, China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197168 Authors: Xiaodong Di Lijian Wang Xiuliang Dai Liu Yang With the rapid increase of the elderly population in China, healthcare services for the elderly have gradually become an important welfare resource. However, the healthcare service for the...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7167: Blockchain in Healthcare: Insights on COVID-19
IJERPH, Vol. 17, Pages 7167: Blockchain in Healthcare: Insights on COVID-19 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197167 Authors: Antonio Fusco Grazia Dicuonzo Vittorio Dell’Atti Marco Tatullo The SARS-CoV2 pandemic has impacted risk management globally. Blockchain has been increasingly applied to healthcare management, as a strategic tool to strengthen operative protocols and to create the proper basis for an efficient and effective...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7166: Encouraging and Enabling Lifestyles and Behaviours to Simultaneously Promote Environmental Sustainability, Health and Equity: Key Policy Messages from INHERIT
IJERPH, Vol. 17, Pages 7166: Encouraging and Enabling Lifestyles and Behaviours to Simultaneously Promote Environmental Sustainability, Health and Equity: Key Policy Messages from INHERIT International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197166 Authors: Ingrid Stegeman Alba Godfrey Maria Romeo-Velilla Ruth Bell Brigit Staatsen Nina van der Vliet Hanneke Kruize George Morris Timothy Taylor Rosa Strube Kirsti Anthun Monica...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7165: Gestational Pesticide Exposure and Child Respiratory Health
IJERPH, Vol. 17, Pages 7165: Gestational Pesticide Exposure and Child Respiratory Health International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197165 Authors: Robyn Gilden Erika Friedmann Katie Holmes Kimberly Yolton Yingying Xu Bruce Lanphear Aimin Chen Joseph Braun Adam Spanier Background: Childhood wheeze may be related to pesticide exposure, and diet and genetics (Paroxonase; PON1) may modify the effects of exposure. Methods:...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7169: Seasonal Changes in Anthropometry, Body Composition, and Physical Fitness and the Relationships with Sporting Success in Young Sub-Elite Judo Athletes: An Exploratory Study
IJERPH, Vol. 17, Pages 7169: Seasonal Changes in Anthropometry, Body Composition, and Physical Fitness and the Relationships with Sporting Success in Young Sub-Elite Judo Athletes: An Exploratory Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197169 Authors: Olaf Prieske Helmi Chaabene Martijn Gäbler Michael Herz Norman Helm Adrian Markov Urs Granacher This exploratory study aimed to monitor long-term seasonal developments...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7164: The Influence of Norm Perception on Pro-Environmental Behavior: A Comparison between the Moderating Roles of Traditional Media and Social Media
IJERPH, Vol. 17, Pages 7164: The Influence of Norm Perception on Pro-Environmental Behavior: A Comparison between the Moderating Roles of Traditional Media and Social Media International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197164 Authors: Ruixia Han Yali Cheng The activation of norm perception can promote pro-environmental behavior. How does media, as important variables in activating norm perception, affect pro-environmental behavior? Through...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7162: A Quantitative Study on Crucial Food Supplies after the 2011 Tohoku Earthquake Based on Time Series Analysis
IJERPH, Vol. 17, Pages 7162: A Quantitative Study on Crucial Food Supplies after the 2011 Tohoku Earthquake Based on Time Series Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197162 Authors: Xiaoxin Zhu Yanyan Wang David Regan Baiqing Sun Awareness of the requested quantity and characteristics of emergency supplies is crucial for facilitating an efficient relief operation. With the aim of focusing on the quantitative study of...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7161: Validity and Reliability of International Physical Activity Questionnaires for Adults across EU Countries: Systematic Review and Meta Analysis
IJERPH, Vol. 17, Pages 7161: Validity and Reliability of International Physical Activity Questionnaires for Adults across EU Countries: Systematic Review and Meta Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197161 Authors: Vedrana Sember Kaja Meh Maroje Sorić Gregor Starc Paulo Rocha Gregor Jurak This review and meta-analysis (PROSPERO registration number: CRD42020138845) critically evaluates test-retest reliability,...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7163: Unemployment and Psychological Distress among Young People during the COVID-19 Pandemic: Psychological Resources and Risk Factors
IJERPH, Vol. 17, Pages 7163: Unemployment and Psychological Distress among Young People during the COVID-19 Pandemic: Psychological Resources and Risk Factors International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197163 Authors: Netta Achdut Tehila Refaeli In the wake of COVID-19, unemployment and its potential deleterious consequences have attracted renewed interest. We examined (1) the association between unemployment, occurring upon the coronavirus...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJERPH, Vol. 17, Pages 7160: Understanding the Public’s Emotions about Cancer: Analysis of Social Media Data
IJERPH, Vol. 17, Pages 7160: Understanding the Public’s Emotions about Cancer: Analysis of Social Media Data International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197160 Authors: Seul Ki Park Hyeoun-Ae Park Jooyun Lee Cancer survivors suffer from emotional distress, which varies depending on several factors. However, existing emotion management programs are insufficient and do not take into consideration all of the factors. Social media provides...
International Journal of Environmental Research and Public Health
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7251: Inhibitory Effect of a Human MicroRNA, miR-6133-5p, on the Fibrotic Activity of Hepatic Stellate Cells in Culture
IJMS, Vol. 21, Pages 7251: Inhibitory Effect of a Human MicroRNA, miR-6133-5p, on the Fibrotic Activity of Hepatic Stellate Cells in Culture International Journal of Molecular Sciences doi: 10.3390/ijms21197251 Authors: Susumu Hamada-Tsutsumi Masaya Onishi Kentaro Matsuura Masanori Isogawa Keigo Kawashima Yusuke Sato Yasuhito Tanaka Background: We recently identified 39 human microRNAs, which effectively suppress hepatitis B virus (HBV) replication in hepatocytes. Chronic...
International Journal of Molecular Sciences
03:00
IJMS, Vol. 21, Pages 7255: The Prognostic Value of Toll-Like Receptors in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis
IJMS, Vol. 21, Pages 7255: The Prognostic Value of Toll-Like Receptors in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis International Journal of Molecular Sciences doi: 10.3390/ijms21197255 Authors: Shrabon Hasnat Roosa Hujanen Bright I. Nwaru Tuula Salo Abdelhakim Salem Head and neck squamous cell carcinoma (HNSCC) is a group of tumours which exhibit low 5 year survival rates. Thus, there is an urgent need to identify biomarkers that may improve...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7254: Functions of Cytochrome c oxidase Assembly Factors
IJMS, Vol. 21, Pages 7254: Functions of Cytochrome c oxidase Assembly Factors International Journal of Molecular Sciences doi: 10.3390/ijms21197254 Authors: Shane A. Watson Gavin P. McStay Cytochrome c oxidase is the terminal complex of eukaryotic oxidative phosphorylation in mitochondria. This process couples the reduction of electron carriers during metabolism to the reduction of molecular oxygen to water and translocation of protons from the internal mitochondrial matrix to the...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7252: Bone Marrow-Derived Mononuclear Cell Transplants Decrease Retinal Gliosis in Two Animal Models of Inherited Photoreceptor Degeneration
IJMS, Vol. 21, Pages 7252: Bone Marrow-Derived Mononuclear Cell Transplants Decrease Retinal Gliosis in Two Animal Models of Inherited Photoreceptor Degeneration International Journal of Molecular Sciences doi: 10.3390/ijms21197252 Authors: Johnny Di Pierdomenico Diego García-Ayuso María Elena Rodríguez González-Herrero David García-Bernal Miguel Blanquer José Manuel Bernal-Garro Ana M García-Hernández Manuel Vidal-Sanz María P Villegas-Pérez Inherited photoreceptor...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7253: Pathogenesis of Eosinophilic Esophagitis: A Comprehensive Review of the Genetic and Molecular Aspects
IJMS, Vol. 21, Pages 7253: Pathogenesis of Eosinophilic Esophagitis: A Comprehensive Review of the Genetic and Molecular Aspects International Journal of Molecular Sciences doi: 10.3390/ijms21197253 Authors: Seohyun Ryu Keum Hwa Lee Kalthoum Tizaoui Salvatore Terrazzino Sarah Cargnin Maria Effenberger Jae Il Shin Andreas Kronbichler Eosinophilic esophagitis (EoE) is a relatively new condition described as an allergic-mediated disease of the esophagus. Clinically,...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7234: The Role of α1-Microglobulin (A1M) in Erythropoiesis and Erythrocyte Homeostasis—Therapeutic Opportunities in Hemolytic Conditions
IJMS, Vol. 21, Pages 7234: The Role of α1-Microglobulin (A1M) in Erythropoiesis and Erythrocyte Homeostasis—Therapeutic Opportunities in Hemolytic Conditions International Journal of Molecular Sciences doi: 10.3390/ijms21197234 Authors: Kristiansson Gram Flygare Hansson Åkerström Storry α1-microglobulin (A1M) is a small protein present in vertebrates including humans. It has several physiologically relevant properties, including binding of heme and radicals...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7249: The Fate of Transplanted Olfactory Progenitors Is Conditioned by the Cell Phenotypes of the Receiver Brain Tissue in Cocultures
IJMS, Vol. 21, Pages 7249: The Fate of Transplanted Olfactory Progenitors Is Conditioned by the Cell Phenotypes of the Receiver Brain Tissue in Cocultures International Journal of Molecular Sciences doi: 10.3390/ijms21197249 Authors: Pourié Grégory Akchiche Nassila Millot Jean-Louis Guéant Jean-Louis Daval Jean-Luc Bossenmeyer-Pourié Carine Among the numerous candidates for cell therapy of the central nervous system (CNS), olfactory progenitors (OPs) represent an interesting...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7242: Pigment Epithelium-Derived Factor (PEDF) Fragments Prevent Mouse Cone Photoreceptor Cell Loss Induced by Focal Phototoxicity In Vivo
IJMS, Vol. 21, Pages 7242: Pigment Epithelium-Derived Factor (PEDF) Fragments Prevent Mouse Cone Photoreceptor Cell Loss Induced by Focal Phototoxicity In Vivo International Journal of Molecular Sciences doi: 10.3390/ijms21197242 Authors: Francisco J. Valiente-Soriano Johnny Di Pierdomenico Diego García-Ayuso Arturo Ortín-Martínez Juan A. Miralles de Imperial-Ollero Alejandro Gallego-Ortega Manuel Jiménez-López M. Paz Villegas-Pérez S. Patricia Becerra Manuel Vidal-Sanz...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7250: Risk Factors and Mouse Models of Abdominal Aortic Aneurysm Rupture
IJMS, Vol. 21, Pages 7250: Risk Factors and Mouse Models of Abdominal Aortic Aneurysm Rupture International Journal of Molecular Sciences doi: 10.3390/ijms21197250 Authors: Smriti Murali Krishna Susan K. Morton Jiaze Li Jonathan Golledge Abdominal aortic aneurysm (AAA) rupture is an important cause of death in older adults. In clinical practice, the most established predictor of AAA rupture is maximum AAA diameter. Aortic diameter is commonly used to assess AAA severity in mouse...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7233: Orthotopic Bone Formation by Streamlined Engineering and Devitalization of Human Hypertrophic Cartilage
IJMS, Vol. 21, Pages 7233: Orthotopic Bone Formation by Streamlined Engineering and Devitalization of Human Hypertrophic Cartilage International Journal of Molecular Sciences doi: 10.3390/ijms21197233 Authors: Sébastien Pigeot Paul Emile Bourgine Jaquiery Claude Celeste Scotti Adam Papadimitropoulos Atanas Todorov Christian Epple Giuseppe M. Peretti Ivan Martin Most bones of the human body form and heal through endochondral ossification, whereby hypertrophic cartilage...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7230: Glucose, Fructose, and Urate Transporters in the Choroid Plexus Epithelium
IJMS, Vol. 21, Pages 7230: Glucose, Fructose, and Urate Transporters in the Choroid Plexus Epithelium International Journal of Molecular Sciences doi: 10.3390/ijms21197230 Authors: Yoichi Chiba Ryuta Murakami Koichi Matsumoto Keiji Wakamatsu Wakako Nonaka Naoya Uemura Ken Yanase Masaki Kamada Masaki Ueno The choroid plexus plays a central role in the regulation of the microenvironment of the central nervous system by secreting the majority of the cerebrospinal...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7235: Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study
IJMS, Vol. 21, Pages 7235: Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study International Journal of Molecular Sciences doi: 10.3390/ijms21197235 Authors: Soon-Young Kim Eun-Hye Lee Eun Na Kim Woo-Chan Son Yeo Hyang Kim Seung-Yoon Park In-San Kim Jung-Eun Kim The placenta undergoes reconstruction at different times during fetal development to supply oxygen and nutrients required throughout pregnancy. To...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7227: Astaxanthin Suppresses PM2.5-Induced Neuroinflammation by Regulating Akt Phosphorylation in BV-2 Microglial Cells
IJMS, Vol. 21, Pages 7227: Astaxanthin Suppresses PM2.5-Induced Neuroinflammation by Regulating Akt Phosphorylation in BV-2 Microglial Cells International Journal of Molecular Sciences doi: 10.3390/ijms21197227 Authors: Ryeong-Eun Kim Chan Young Shin Seol-Heui Han Kyoung Ja Kwon Air pollution has become one of the most serious issues for human health and has been shown to be particularly concerning for neural and cognitive health. Recent studies suggest that fine particulate...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7231: Oral Submucous Fibrosis: A Review on Biomarkers, Pathogenic Mechanisms, and Treatments
IJMS, Vol. 21, Pages 7231: Oral Submucous Fibrosis: A Review on Biomarkers, Pathogenic Mechanisms, and Treatments International Journal of Molecular Sciences doi: 10.3390/ijms21197231 Authors: Yen-Wen Shen Yin-Hwa Shih Lih-Jyh Fuh Tzong-Ming Shieh Oral submucous fibrosis (OSF) is a collagen deposition disorder that affects a patient’s oral function and quality of life. It may also potentially transform into malignancy. This review summarizes the risk factors, pathogenic...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7248: Biomarkers Suggesting Favorable Prognostic Outcomes in Sudden Sensorineural Hearing Loss
IJMS, Vol. 21, Pages 7248: Biomarkers Suggesting Favorable Prognostic Outcomes in Sudden Sensorineural Hearing Loss International Journal of Molecular Sciences doi: 10.3390/ijms21197248 Authors: Jeon Gang Doo Dokyoung Kim Yong Kim Myung Chul Yoo Sung Su Kim Jeewon Ryu Seung Geun Yeo Sudden sensorineural hearing loss (SSNHL) is a medical emergency, making detailed examination to determine possible causes and early treatment important. However, etiological examinations...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7245: TRIM28 Regulates Dlk1 Expression in Adipogenesis
IJMS, Vol. 21, Pages 7245: TRIM28 Regulates Dlk1 Expression in Adipogenesis International Journal of Molecular Sciences doi: 10.3390/ijms21197245 Authors: Hsin-Pin Lu Chieh-Ju Lin Wen-Ching Chen Yao-Jen Chang Sheng-Wei Lin Hsin-Hui Wang Ching-Jin Chang The tripartite motif-containing protein 28 (TRIM28) is a transcription corepressor, interacting with histone deacetylase and methyltransferase complexes. TRIM28 is a crucial regulator in development and differentiation....
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7246: The Role of Metabolic Factors in Renal Cancers
IJMS, Vol. 21, Pages 7246: The Role of Metabolic Factors in Renal Cancers International Journal of Molecular Sciences doi: 10.3390/ijms21197246 Authors: Jacek Rysz Beata Franczyk Janusz Ławiński Robert Olszewski Anna Gluba-Brzózka An increasing number of evidence indicates that metabolic factors may play an important role in the development and progression of certain types of cancers, including renal cell carcinoma (RCC). This tumour is the most common kidney cancer which...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7244: Metabolomics in Sleep, Insomnia and Sleep Apnea
IJMS, Vol. 21, Pages 7244: Metabolomics in Sleep, Insomnia and Sleep Apnea International Journal of Molecular Sciences doi: 10.3390/ijms21197244 Authors: Elke Humer Christoph Pieh Georg Brandmayr Sleep-wake disorders are highly prevalent disorders, which can lead to negative effects on cognitive, emotional and interpersonal functioning, and can cause maladaptive metabolic changes. Recent studies support the notion that metabolic processes correlate with sleep. The study of metabolite...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7243: Rolling Circle Amplification (RCA)-Mediated Genome-Wide ihpRNAi Mutant Library Construction in Brassica napus
IJMS, Vol. 21, Pages 7243: Rolling Circle Amplification (RCA)-Mediated Genome-Wide ihpRNAi Mutant Library Construction in Brassica napus International Journal of Molecular Sciences doi: 10.3390/ijms21197243 Authors: Shengbo Zhao Junling Luo Xinhua Zeng Keqi Li Rong Yuan Li Zhu Xiaofei Li Gang Wu Xiaohong Yan With the successful completion of genomic sequencing for Brassica napus, identification of novel genes, determination of functions performed by genes, and...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7247: Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling
IJMS, Vol. 21, Pages 7247: Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling International Journal of Molecular Sciences doi: 10.3390/ijms21197247 Authors: Jyun-Bin Huang Shih-Pin Hsu Hsiu-Yung Pan Shang-Der Chen Shu-Fang Chen Tsu-Kung Lin Xuan-Ping Liu Jie-Hau Li Nai-Ching Chen Chia-Wei Liou Chung-Yao...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7238: Natural Catalytic IgGs Hydrolyzing Histones in Schizophrenia: Are They the Link between Humoral Immunity and Inflammation?
IJMS, Vol. 21, Pages 7238: Natural Catalytic IgGs Hydrolyzing Histones in Schizophrenia: Are They the Link between Humoral Immunity and Inflammation? International Journal of Molecular Sciences doi: 10.3390/ijms21197238 Authors: Evgeny A. Ermakov Daria A. Parshukova Georgy A. Nevinsky Valentina N. Buneva Schizophrenia is known to be accompanied not only with an imbalance in the neurotransmitter systems but also with immune system dysregulation and chronic low-grade inflammation....
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7240: Biological Functions of Prokaryotic Amyloids in Interspecies Interactions: Facts and Assumptions
IJMS, Vol. 21, Pages 7240: Biological Functions of Prokaryotic Amyloids in Interspecies Interactions: Facts and Assumptions International Journal of Molecular Sciences doi: 10.3390/ijms21197240 Authors: Anastasiia O. Kosolapova Kirill S. Antonets Mikhail V. Belousov Anton A. Nizhnikov Amyloids are fibrillar protein aggregates with an ordered spatial structure called “cross-β”. While some amyloids are associated with development of approximately 50...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7239: Overexpression of UGT74E2, an Arabidopsis IBA Glycosyltransferase, Enhances Seed Germination and Modulates Stress Tolerance via ABA Signaling in Rice
IJMS, Vol. 21, Pages 7239: Overexpression of UGT74E2, an Arabidopsis IBA Glycosyltransferase, Enhances Seed Germination and Modulates Stress Tolerance via ABA Signaling in Rice International Journal of Molecular Sciences doi: 10.3390/ijms21197239 Authors: Ting Wang Pan Li Tianjiao Mu Guangrui Dong Chengchao Zheng Shanghui Jin Tingting Chen Bingkai Hou Yanjie Li UDP-glycosyltransferases (UGTs) play key roles in modulating plant development and responses to environmental...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7237: Maternal Adenine-Induced Chronic Kidney Disease Programs Hypertension in Adult Male Rat Offspring: Implications of Nitric Oxide and Gut Microbiome Derived Metabolites
IJMS, Vol. 21, Pages 7237: Maternal Adenine-Induced Chronic Kidney Disease Programs Hypertension in Adult Male Rat Offspring: Implications of Nitric Oxide and Gut Microbiome Derived Metabolites International Journal of Molecular Sciences doi: 10.3390/ijms21197237 Authors: Chien-Ning Hsu Hung-Wei Yang Chih-Yao Hou Guo-Ping Chang-Chien Sufan Lin You-Lin Tain Maternal chronic kidney disease (CKD) during pregnancy causes adverse fetal programming. Nitric oxide (NO) deficiency,...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7236: Protective Effects of Simvastatin on Endotoxin-Induced Acute Kidney Injury through Activation of Tubular Epithelial Cells’ Survival and Hindering Cytochrome C-Mediated Apoptosis
IJMS, Vol. 21, Pages 7236: Protective Effects of Simvastatin on Endotoxin-Induced Acute Kidney Injury through Activation of Tubular Epithelial Cells’ Survival and Hindering Cytochrome C-Mediated Apoptosis International Journal of Molecular Sciences doi: 10.3390/ijms21197236 Authors: Lana Nežić Ranko Škrbić Ljiljana Amidžić Radoslav Gajanin Zoran Milovanović Eugenie Nepovimova Kamil Kuča Vesna Jaćević Increasing evidence suggests that apoptosis of tubular cells and...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7241: Characterization of Local and Systemic Impact of Whitefly (Bemisia tabaci) Feeding and Whitefly-Transmitted Tomato Mottle Virus Infection on Tomato Leaves by Comprehensive Proteomics
IJMS, Vol. 21, Pages 7241: Characterization of Local and Systemic Impact of Whitefly (Bemisia tabaci) Feeding and Whitefly-Transmitted Tomato Mottle Virus Infection on Tomato Leaves by Comprehensive Proteomics International Journal of Molecular Sciences doi: 10.3390/ijms21197241 Authors: Aaron J. Ogden Wardatou Boukari Alba Nava Natalia Lucinda Garry Sunter Wayne R. Curtis Joshua N. Adkins Jane E. Polston Tomato mottle virus (ToMoV) is a single-stranded DNA (ssDNA)...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7232: MicroRNA-31 Regulates Expression of Wntless in Both Drosophila melanogaster and Human Oral Cancer Cells
IJMS, Vol. 21, Pages 7232: MicroRNA-31 Regulates Expression of Wntless in Both Drosophila melanogaster and Human Oral Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21197232 Authors: Ji Eun Jung Joo Young Lee In Ryoung Kim Sang Mee Park Ji Wan Kang Yun Hak Kim Hae Ryoun Park Ji Hye Lee Recent comparative studies have indicated distinct expression profiles of short, non-coding microRNAs (miRNAs) in various types of cancer, including oral...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7229: Differential Effect of Extracellular Acidic Environment on IL-1β Released from Human and Mouse Phagocytes
IJMS, Vol. 21, Pages 7229: Differential Effect of Extracellular Acidic Environment on IL-1β Released from Human and Mouse Phagocytes International Journal of Molecular Sciences doi: 10.3390/ijms21197229 Authors: Petra Sušjan Mojca Benčina Iva Hafner-Bratkovič Areas of locally decreased pH are characteristic for many chronic inflammatory diseases such as atherosclerosis and rheumatoid arthritis, acute pathologies such as ischemia reperfusion, and tumor microenvironment. The data...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7228: Immunological Memory in Imiquimod-Induced Murine Model of Psoriasiform Dermatitis
IJMS, Vol. 21, Pages 7228: Immunological Memory in Imiquimod-Induced Murine Model of Psoriasiform Dermatitis International Journal of Molecular Sciences doi: 10.3390/ijms21197228 Authors: Kevin Fenix Danushka K. Wijesundara Allison J. Cowin Branka Grubor-Bauk Zlatko Kopecki Psoriasis is a common chronic inflammatory skin condition manifested by T cell responses and characterized by preferential recurrence at previously inflamed sites upon withdrawal of treatment. The site-specific...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7226: Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice
IJMS, Vol. 21, Pages 7226: Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice International Journal of Molecular Sciences doi: 10.3390/ijms21197226 Authors: Masateru Kondo Yuki Izawa-Ishizawa Mitsuhiro Goda Mayuko Hosooka Yuu Kagimoto Naoko Saito Rie Matsuoka Yoshito Zamami Masayuki Chuma Kenta Yagi Kenshi Takechi Koichi Tsuneyama Keisuke Ishizawa Atherosclerosis-related acute aortic syndromes,...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7225: The Role of SHIP1 on Apoptosis and Autophagy in the Adipose Tissue of Obese Mice
IJMS, Vol. 21, Pages 7225: The Role of SHIP1 on Apoptosis and Autophagy in the Adipose Tissue of Obese Mice International Journal of Molecular Sciences doi: 10.3390/ijms21197225 Authors: Jae Hun Jeong Eun Bee Choi Hye Min Jang Yu Jeong Ahn Hyeong Seok An Jong Youl Lee Gyeongah Park Eun Ae Jeong Hyun Joo Shin Jaewoong Lee Kyung Eun Kim Gu Seob Roh Obesity-induced adipocyte apoptosis promotes inflammation and insulin resistance. Src homology domain-containing...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
IJMS, Vol. 21, Pages 7224: Fatty Acid Synthase Beta Dehydratase in the Lipid Biosynthesis Pathway Is Required for Conidiogenesis, Pigmentation and Appressorium Formation in Magnaporthe oryzae S6
IJMS, Vol. 21, Pages 7224: Fatty Acid Synthase Beta Dehydratase in the Lipid Biosynthesis Pathway Is Required for Conidiogenesis, Pigmentation and Appressorium Formation in Magnaporthe oryzae S6 International Journal of Molecular Sciences doi: 10.3390/ijms21197224 Authors: Vaanee Sangappillai Kalaivani Nadarajah Lipid biosynthesis produces glycerol, which is important in fueling turgor pressure necessary for germination and penetration of plant host by fungi. As the relationship between...
International Journal of Molecular Sciences
Wed Sep 30, 2020 03:00
Healthcare, Vol. 8, Pages 374: A Qualitative Study Investigating the Barriers to the Implementation of the ‘Sepsis Six Care Bundle’ in Maternity Wards
Healthcare, Vol. 8, Pages 374: A Qualitative Study Investigating the Barriers to the Implementation of the ‘Sepsis Six Care Bundle’ in Maternity Wards Healthcare doi: 10.3390/healthcare8040374 Authors: Nouf Abutheraa Alexander B. Mullen June Grant Gazala Akram Background: In 2014, the Sepsis Six Care Bundle (SSCB) was introduced into a Scottish health region to improve patient outcomes. Poor compliance was demonstrated with the SSCB across different specialities. This study...
Healthcare
03:00
Healthcare, Vol. 8, Pages 373: Incidence of Post-Traumatic Stress Disorder After Coronavirus Disease
Healthcare, Vol. 8, Pages 373: Incidence of Post-Traumatic Stress Disorder After Coronavirus Disease Healthcare doi: 10.3390/healthcare8040373 Authors: Min Cheol Chang Donghwi Park Background: The coronavirus disease (COVID-19) emerged from China and rapidly spread to many other countries. In this study, we investigated the prevalence of post-traumatic stress disorder (PTSD) among patients with COVID-19 who were treated and discharged from a university hospital in Daegu, Korea. Methods:...
Healthcare
Wed Sep 30, 2020 03:00
Healthcare, Vol. 8, Pages 372: The Characteristics of Adjacent Anatomy of Mandibular Third Molar Germs: A CBCT Pilot Study in Patients with Osteogenesis Imperfecta
Healthcare, Vol. 8, Pages 372: The Characteristics of Adjacent Anatomy of Mandibular Third Molar Germs: A CBCT Pilot Study in Patients with Osteogenesis Imperfecta Healthcare doi: 10.3390/healthcare8040372 Authors: Giacomo D’Angeli Daniela Messineo Mara Riminucci Alessandro Corsi Mauro Celli Iole Vozza Gian Luca Sfasciotti (1) Objectives: The aim of our study was to investigate the anatomical features of lower third molar and its adjacent anatomical connections in type...
Healthcare
Wed Sep 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 942: Physiologically Based Pharmacokinetic Modeling of Transdermal Selegiline and Its Metabolites for the Evaluation of Disposition Differences between Healthy and Special Populations
Pharmaceutics, Vol. 12, Pages 942: Physiologically Based Pharmacokinetic Modeling of Transdermal Selegiline and Its Metabolites for the Evaluation of Disposition Differences between Healthy and Special Populations Pharmaceutics doi: 10.3390/pharmaceutics12100942 Authors: Santosh Kumar Puttrevu Sumit Arora Sebastian Polak Nikunj Kumar Patel A physiologically based pharmacokinetic (PBPK) model of selegiline (SEL), and its metabolites, was developed in silico to evaluate the disposition...
Pharmaceutics
Wed Sep 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 940: Therapeutic Apheresis, Circulating PLD, and Mucocutaneous Toxicity: Our Clinical Experience through Four Years
Pharmaceutics, Vol. 12, Pages 940: Therapeutic Apheresis, Circulating PLD, and Mucocutaneous Toxicity: Our Clinical Experience through Four Years Pharmaceutics doi: 10.3390/pharmaceutics12100940 Authors: Stanislav Filip Ondřej Kubeček Jiří Špaček Miriam Lánská Milan Bláha Jiřina Martínková Cancer treatment has been greatly improved by the combined use of targeted therapies and novel biotechnological methods. Regarding the former, pegylated liposomal doxorubicin (PLD) has...
Pharmaceutics
Wed Sep 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 941: Preparation of Co-Amorphous Systems by Freeze-Drying
Pharmaceutics, Vol. 12, Pages 941: Preparation of Co-Amorphous Systems by Freeze-Drying Pharmaceutics doi: 10.3390/pharmaceutics12100941 Authors: Melvin Wostry Hanna Plappert Holger Grohganz Freeze-drying was evaluated as a production technique for co-amorphous systems of a poorly water-soluble drug. Naproxen was freeze-dried together with arginine and lysine as co-former. To increase the solubility of naproxen in the starting solution, the applicability of five surfactants was...
Pharmaceutics
Wed Sep 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 938: The Development and Validation of a Novel “Dual Cocktail” Probe for Cytochrome P450s and Transporter Functions to Evaluate Pharmacokinetic Drug-Drug and Herb-Drug Interactions
Pharmaceutics, Vol. 12, Pages 938: The Development and Validation of a Novel “Dual Cocktail” Probe for Cytochrome P450s and Transporter Functions to Evaluate Pharmacokinetic Drug-Drug and Herb-Drug Interactions Pharmaceutics doi: 10.3390/pharmaceutics12100938 Authors: Mihwa Kwon Ji-Hyeon Jeon Min-Koo Choi Im-Sook Song This study was designed to develop and validate a 10 probe drug cocktail named “Dual Cocktail”, composed of caffeine (Cyp1a2 in rat and CYP1A2...
Pharmaceutics
Wed Sep 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 939: Development of Liposomal Vesicles for Osimertinib Delivery to EGFR Mutation—Positive Lung Cancer Cells
Pharmaceutics, Vol. 12, Pages 939: Development of Liposomal Vesicles for Osimertinib Delivery to EGFR Mutation—Positive Lung Cancer Cells Pharmaceutics doi: 10.3390/pharmaceutics12100939 Authors: Paulina Skupin-Mrugalska Tamara Minko Osimertinib (OSI, AZD9291), is a third-generation, irreversible tyrosine kinase inhibitor (TKI) of the epidermal growth factor receptor (EGFR) that selectively inhibits both EGFR-TKI–sensitizing and EGFR T790M resistance mutations. OSI has been...
Pharmaceutics
Wed Sep 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 934: Repositioning N-Acetylcysteine (NAC): NAC-Loaded Electrospun Drug Delivery Scaffolding for Potential Neural Tissue Engineering Application
Pharmaceutics, Vol. 12, Pages 934: Repositioning N-Acetylcysteine (NAC): NAC-Loaded Electrospun Drug Delivery Scaffolding for Potential Neural Tissue Engineering Application Pharmaceutics doi: 10.3390/pharmaceutics12100934 Authors: Gillian D. Mahumane Pradeep Kumar Viness Pillay Yahya E. Choonara Traumatic brain injury (TBI) presents a serious challenge for modern medicine due to the poor regenerative capabilities of the brain, complex pathophysiology, and lack of effective...
Pharmaceutics
Wed Sep 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 936: A Compartment-Based Mathematical Model for Studying Convective Aerosol Transport in Newborns Receiving Nebulized Drugs during Noninvasive Respiratory Support
Pharmaceutics, Vol. 12, Pages 936: A Compartment-Based Mathematical Model for Studying Convective Aerosol Transport in Newborns Receiving Nebulized Drugs during Noninvasive Respiratory Support Pharmaceutics doi: 10.3390/pharmaceutics12100936 Authors: Francesco Tarantini Ilaria Milesi Xabier Murgia Federico Bianco Raffaele L. Dellacà Nebulization could be a valuable solution to administer drugs to neonates receiving noninvasive respiratory support. Small and irregular tidal...
Pharmaceutics
Wed Sep 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 935: Completing the Enalaprilat Excretion Pathway—Renal Handling by the Proximal Tubule
Pharmaceutics, Vol. 12, Pages 935: Completing the Enalaprilat Excretion Pathway—Renal Handling by the Proximal Tubule Pharmaceutics doi: 10.3390/pharmaceutics12100935 Authors: Nori J. L. Smeets Carlijn H. C. Litjens Jeroen J. M. W. van den Heuvel Hedwig van Hove Petra van den Broek Frans G. M. Russel Jan B. Koenderink Saskia N. de Wildt Background: Enalapril is often used in the treatment of cardiovascular diseases. Clinical data suggest that the urinary excretion...
Pharmaceutics
Wed Sep 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 937: Brain Delivery of Single-Domain Antibodies: A Focus on VHH and VNAR
Pharmaceutics, Vol. 12, Pages 937: Brain Delivery of Single-Domain Antibodies: A Focus on VHH and VNAR Pharmaceutics doi: 10.3390/pharmaceutics12100937 Authors: Elodie Pothin Dominique Lesuisse Pierre Lafaye Passive immunotherapy, i.e., treatment with therapeutic antibodies, has been increasingly used over the last decade in several diseases such as cancers or inflammation. However, these proteins have some limitations that single-domain antibodies could potentially solve. One...
Pharmaceutics
Wed Sep 30, 2020 03:00
Viruses, Vol. 12, Pages 1116: In Vitro and In Vivo Models to Study the Zoonotic Mosquito-Borne Usutu Virus
Viruses, Vol. 12, Pages 1116: In Vitro and In Vivo Models to Study the Zoonotic Mosquito-Borne Usutu Virus Viruses doi: 10.3390/v12101116 Authors: Emna Benzarti Mutien Garigliany Usutu virus (USUV), a mosquito-borne zoonotic flavivirus discovered in South Africa in 1959, has spread to many European countries over the last 20 years. The virus is currently a major concern for animal health due to its expanding host range and the growing number of avian mass mortality events. Although...
Viruses
Wed Sep 30, 2020 03:00
Viruses, Vol. 12, Pages 1113: Wild Boar as a Sylvatic Reservoir of Hepatitis E Virus in Poland: A Cross-Sectional Population Study
Viruses, Vol. 12, Pages 1113: Wild Boar as a Sylvatic Reservoir of Hepatitis E Virus in Poland: A Cross-Sectional Population Study Viruses doi: 10.3390/v12101113 Authors: Iwona Kozyra Artur Jabłoński Ewelina Bigoraj Artur Rzeżutka The most important wildlife species in the epidemiology of hepatitis E virus (HEV) infections are wild boars, which are also the main reservoir of the virus in a sylvatic environment. The aim of the study was a serological and molecular assessment...
Viruses
Wed Sep 30, 2020 03:00
Viruses, Vol. 12, Pages 1114: Expansion and Refinement of Deep Sequence-Coupled Biopanning Technology for Epitope-Specific Antibody Responses in Human Serum
Viruses, Vol. 12, Pages 1114: Expansion and Refinement of Deep Sequence-Coupled Biopanning Technology for Epitope-Specific Antibody Responses in Human Serum Viruses doi: 10.3390/v12101114 Authors: Nikole L. Warner Alexandria C. Linville Susan B. Core Brechla Moreno Juan M. Pascale David S. Peabody Bryce Chackerian Kathryn M. Frietze Identifying the specific epitopes targeted by antibodies elicited in response to infectious diseases is important for developing vaccines...
Viruses
Wed Sep 30, 2020 03:00
Viruses, Vol. 12, Pages 1112: HBV Prevention and Treatment in Countries of Central Asia and the Caucasus
Viruses, Vol. 12, Pages 1112: HBV Prevention and Treatment in Countries of Central Asia and the Caucasus Viruses doi: 10.3390/v12101112 Authors: Daulet Amerzhanov Indira Suleimenova Salima Davlidova Zhamilya Nugmanova Syed Ali The countries of Central Asia and the Caucasus are linked by travel and trade, which is promoted by visa-free mobility across borders. Unfortunately, this migrant mobility has given rise to the transmission of various infections within this region....
Viruses
Wed Sep 30, 2020 03:00
Viruses, Vol. 12, Pages 1115: NMR Studies of Retroviral Genome Packaging
Viruses, Vol. 12, Pages 1115: NMR Studies of Retroviral Genome Packaging Viruses doi: 10.3390/v12101115 Authors: Patricia S. Boyd Janae B. Brown Joshua D. Brown Jonathan Catazaro Issac Chaudry Pengfei Ding Xinmei Dong Jan Marchant Colin T. O’Hern Karndeep Singh Canessa Swanson Michael F. Summers Saif Yasin Nearly all retroviruses selectively package two copies of their unspliced RNA genomes from a cellular milieu that contains a substantial excess...
Viruses
Wed Sep 30, 2020 03:00
Viruses, Vol. 12, Pages 1111: p24G1 Encoded by Grapevine Leafroll-Associated Virus 1 Suppresses RNA Silencing and Elicits Hypersensitive Response-Like Necrosis in Nicotiana Species
Viruses, Vol. 12, Pages 1111: p24G1 Encoded by Grapevine Leafroll-Associated Virus 1 Suppresses RNA Silencing and Elicits Hypersensitive Response-Like Necrosis in Nicotiana Species Viruses doi: 10.3390/v12101111 Authors: Chen-Wei Zhang Qing Liu Qi Zeng Wen-Ting Huang Qi Wang Yu-Qin Cheng Grapevine leafroll-associated virus 1 (GLRaV-1) is a major pathogen associated with grapevine leafroll disease. However, the molecular mechanisms underlying GLRaV-1 interactions with plant...
Viruses
Wed Sep 30, 2020 03:00
Viruses, Vol. 12, Pages 1110: Role of Viral Ribonucleoproteins in Human Papillomavirus Type 16 Gene Expression
Viruses, Vol. 12, Pages 1110: Role of Viral Ribonucleoproteins in Human Papillomavirus Type 16 Gene Expression Viruses doi: 10.3390/v12101110 Authors: Naoko Kajitani Stefan Schwartz Human papillomaviruses (HPVs) depend on the cellular RNA-processing machineries including alternative RNA splicing and polyadenylation to coordinate HPV gene expression. HPV RNA processing is controlled by cis-regulatory RNA elements and trans-regulatory factors since the HPV splice sites are suboptimal....
Viruses
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2745: Integrating C- and L-Band SAR Imagery for Detailed Flood Monitoring of Remote Vegetated Areas
Water, Vol. 12, Pages 2745: Integrating C- and L-Band SAR Imagery for Detailed Flood Monitoring of Remote Vegetated Areas Water doi: 10.3390/w12102745 Authors: Alberto Refice Marina Zingaro Annarita D’Addabbo Marco Chini Flood detection and monitoring is increasingly important, especially on remote areas such as African tropical river basins, where ground investigations are difficult. We present an experiment aimed at integrating multi-temporal and multi-source data from the...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2744: Investigating an Innovative Sea-Based Strategy to Mitigate Coastal City Flood Disasters and Its Feasibility Study for Brisbane, Australia
Water, Vol. 12, Pages 2744: Investigating an Innovative Sea-Based Strategy to Mitigate Coastal City Flood Disasters and Its Feasibility Study for Brisbane, Australia Water doi: 10.3390/w12102744 Authors: Usman Khalil Shu-Qing Yang Muttucumaru Sivakumar Keith Enever Mariam Sajid Muhammad Zain Bin Riaz This study examines an innovative Coastal Reservoir (CR) technique as a feasible solution for flood adaptation and mitigation in the Brisbane River Estuary (BRE), Australia,...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2742: Impact Assessment and Geochemical Background Analysis of Surface Water Quality of Catchments Affected by the 2017 Portugal Wildfires
Water, Vol. 12, Pages 2742: Impact Assessment and Geochemical Background Analysis of Surface Water Quality of Catchments Affected by the 2017 Portugal Wildfires Water doi: 10.3390/w12102742 Authors: Mário David Sequeira Ana Maria Castilho Pedro Alexandre Dinis Alexandre Oliveira Tavares In October 2017, the Mondego hydrological basin was devastated by multiple wildfires. To understand the impacts that these had on surface water quality, monthly monitoring campaigns were implemented...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2741: A Vine Copula-Based Modeling for Identification of Multivariate Water Pollution Risk in an Interconnected River System Network
Water, Vol. 12, Pages 2741: A Vine Copula-Based Modeling for Identification of Multivariate Water Pollution Risk in an Interconnected River System Network Water doi: 10.3390/w12102741 Authors: Ruolan Yu Rui Yang Chen Zhang Maria Špoljar Natalia Kuczyńska-Kippen Guoqing Sang The Interconnected River System Network (IRSN) has become a popular and useful measure to realize the long-term health and stability of water bodies. However, there are lots of uncertain consequences...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2743: Chivor’s Life Extension Project (CLEP): From Sediment Management to Development of a New Intake System
Water, Vol. 12, Pages 2743: Chivor’s Life Extension Project (CLEP): From Sediment Management to Development of a New Intake System Water doi: 10.3390/w12102743 Authors: David A. del Río Hugo Moffett César Nieto-Londoño Rafael E. Vásquez Ana Escudero-Atehortúa Sedimentation is an important issue that has been studied for the watershed of reservoirs, since it increases operational costs of hydropower installations, reduces the life expectancy, and compromises the generation...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2739: Understanding the Hydropower and Potential Climate Change Impact on the Himalayan River Regimes—A Study of Local Perceptions and Responses from Himachal Pradesh, India
Water, Vol. 12, Pages 2739: Understanding the Hydropower and Potential Climate Change Impact on the Himalayan River Regimes—A Study of Local Perceptions and Responses from Himachal Pradesh, India Water doi: 10.3390/w12102739 Authors: Netrananda Sahu Takahiro Sayama Atul Saini Arpita Panda Kaoru Takara The Himalayas have become synonymous with the hydropower developments for larger electricity demands of India’s energy sector. In the Himachal Himalayas though, there...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2740: Variational Bayesian Neural Network for Ensemble Flood Forecasting
Water, Vol. 12, Pages 2740: Variational Bayesian Neural Network for Ensemble Flood Forecasting Water doi: 10.3390/w12102740 Authors: Xiaoyan Zhan Hui Qin Yongqi Liu Liqiang Yao Wei Xie Guanjun Liu Jianzhong Zhou Disastrous floods are destructive and likely to cause widespread economic losses. An understanding of flood forecasting and its potential forecast uncertainty is essential for water resource managers. Reliable forecasting may provide future streamflow information...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2735: Supporter Profiling in Recycled Water Reuse: Evidence from Meta-Analysis
Water, Vol. 12, Pages 2735: Supporter Profiling in Recycled Water Reuse: Evidence from Meta-Analysis Water doi: 10.3390/w12102735 Authors: Lingyan Li Mimi Duan Hanliang Fu Recycled water is considered as a viable alternative water source, and its use is of great significance in dealing with the shortage of water resources. However, it is often rejected by the public during its promotion. To identity the common social attributes of proponents of recycled water, it is essential to...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2738: Sustainable Intensification of Agriculture in the Context of the COVID-19 Pandemic: Prospects for the Future
Water, Vol. 12, Pages 2738: Sustainable Intensification of Agriculture in the Context of the COVID-19 Pandemic: Prospects for the Future Water doi: 10.3390/w12102738 Authors: Prasanna Venkatesh Sampath Gaddam Sai Jagadeesh Chandra Sekhar Bahinipati The COVID-19 pandemic is adversely impacting food and nutrition security and requires urgent attention from policymakers. Sustainable intensification of agriculture is one strategy that attempts to increase food production without adversely...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2736: Simulating the Impact of Climate Change with Different Reservoir Operating Strategies on Sedimentation of the Mangla Reservoir, Northern Pakistan
Water, Vol. 12, Pages 2736: Simulating the Impact of Climate Change with Different Reservoir Operating Strategies on Sedimentation of the Mangla Reservoir, Northern Pakistan Water doi: 10.3390/w12102736 Authors: Muhammad Adnan Khan Jürgen Stamm Sajjad Haider Reservoir sedimentation reduces the gross storage capacity of dams and also negatively impacts turbine functioning, posing a danger to turbine inlets. When the sediment delta approaches the dam, further concerns arise regarding...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2734: Assessing the Climate Tendency over the Yangtze River Delta, China: Properties, Dry/Wet Event Frequencies, and Causes
Water, Vol. 12, Pages 2734: Assessing the Climate Tendency over the Yangtze River Delta, China: Properties, Dry/Wet Event Frequencies, and Causes Water doi: 10.3390/w12102734 Authors: Yanfei Wu Yu Xu In view of the important role to in revealing climate wet/dry tendency, Standardized Precipitation Index (SPI) was applied to identify wetness/dryness trends and their relationship with large-scale climate oscillations in the Yangtze River Delta (YRD) from 1957 to 2016. The daily precipitation...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2737: Water Balance for a Tropical Lake in the Volcanic Highlands: Lake Tana, Ethiopia
Water, Vol. 12, Pages 2737: Water Balance for a Tropical Lake in the Volcanic Highlands: Lake Tana, Ethiopia Water doi: 10.3390/w12102737 Authors: Muluken L. Alemu Abeyou W. Worqlul Fasikaw A. Zimale Seifu A. Tilahun Tammo S. Steenhuis Lakes hold most of the freshwater resources in the world. Safeguarding these in a changing environment is a major challenge. The 3000 km2 Lake Tana in the headwaters of the Blue Nile in Ethiopia is one of these lakes. It is situated in a zone...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2732: Applicability of Benthic Diatom Indices Combined with Water Quality Valuation for Dish Lake from Nanjishan Nature Reserve, Lake Poyang
Water, Vol. 12, Pages 2732: Applicability of Benthic Diatom Indices Combined with Water Quality Valuation for Dish Lake from Nanjishan Nature Reserve, Lake Poyang Water doi: 10.3390/w12102732 Authors: Junfei Yang Yong Ji Ruyu Yan Xingchen Liu Jie Zhang Naichen Wu Kai Wang Benthic diatom indices developed in the Europe Union have been widely accepted as indicators of the trophic state and water quality in freshwater ecosystems. In China, most of the benthic diatom-based...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2733: Application of Model Predictive Control for Large-Scale Inverted Siphon in Water Distribution System in the Case of Emergency Operation
Water, Vol. 12, Pages 2733: Application of Model Predictive Control for Large-Scale Inverted Siphon in Water Distribution System in the Case of Emergency Operation Water doi: 10.3390/w12102733 Authors: Zheli Zhu Guanghua Guan Zhonghao Mao Kang Wang Shixiang Gu Gang Chen The emergency control of Menglou~Qifang inverted siphon, which is about 72 km long, is the key to the safety of the Northern Hubei Water Transfer Project. Given the complicated layout of this project, traditional...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2730: On the Rainfall Intensity–Duration–Frequency Curves, Partial-Area Effect and the Rational Method: Theory and the Engineering Practice
Water, Vol. 12, Pages 2730: On the Rainfall Intensity–Duration–Frequency Curves, Partial-Area Effect and the Rational Method: Theory and the Engineering Practice Water doi: 10.3390/w12102730 Authors: José Nilson B. Campos Ticiana Marinho de Carvalho Studart Francisco de Assis de Souza Filho Victor Costa Porto This research evaluates the partial-area effect and its relationship with the rainfall intensity–duration–frequency (IDF) equations. In the Rational...
Water
Wed Sep 30, 2020 03:00
Water, Vol. 12, Pages 2731: Long-Term (2001–2020) Nutrient Transport from a Small Boreal Agricultural Watershed: Hydrological Control and Potential of Retention Ponds
Water, Vol. 12, Pages 2731: Long-Term (2001–2020) Nutrient Transport from a Small Boreal Agricultural Watershed: Hydrological Control and Potential of Retention Ponds Water doi: 10.3390/w12102731 Authors: Sari Uusheimo Tiina Tulonen Jussi Huotari Lauri Arvola Agriculture contributes significantly to phosphorus and nitrogen loading in southern Finland. Climate change with higher winter air temperatures and precipitation may also promote loading increase further. We analyzed long-term...
Water
Wed Sep 30, 2020 03:00

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