Analysis of vascular-associated factors and the prognosis of poorly differentiated hypopharyngeal carcinoma. Oncol Lett. 2020 Nov;20(5):271 Authors: Guo W, Yin G, Liu H, Duan H, Huang Z Abstract The aim of the present study was to analyze the characteristics of angiogenic factors in patients with hypopharyngeal cancer, and to study the effects of these factors on induction chemotherapy, patient prognosis and survival. Data from 60 eligible...
Wed Sep 30, 2020 14:10
Cortical neurophysiology of primary isolated dystonia and non-dystonic adults: a meta-analysis. Eur J Neurosci. 2020 Sep 29;: Authors: McCambridge AB, Bradnam LV Abstract Transcranial magnetic stimulation (TMS) is a non-invasive method to assess neurophysiology of the primary motor cortex in humans. Dystonia is a poorly understood neurological movement disorder, often presenting in an idiopathic, isolated form across different parts of the...
Wed Sep 30, 2020 14:14
The potential of cystatin C as a predictive biomarker in breast cancer. Expert Rev Anticancer Ther. 2020 Sep 29;: Authors: Leto G, Sepporta MV Abstract INTRODUCTION: Breast cancer (BCa) is the leading cause of cancer-related deaths among women. Numerous efforts are being directed towards identifying novel tissue and/or circulating molecular markers that may help clinicians in detecting early stage BCa patients and in providing an accurate estimation...
Wed Sep 30, 2020 14:15
Publication date: Available online 30 September 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Alexandre Helbert, Emmanuel Gaud, Tim Segers, Catherine Botteron, Peter Frinking, Victor Jeannot
Wed Sep 30, 2020 14:17
Publication date: November 2020Source: European Journal of Cancer, Volume 139Author(s): Carmen Salvador-Coloma, Ana Santaballa, Elena Sanmartín, David Calvo, Ana García, David Hervás, Lourdes Cordón, Guillermo Quintas, Francisco Ripoll, Joaquín Panadero, Jaime Font de Mora
Wed Sep 30, 2020 14:22
Publication date: November 2020Source: European Journal of Cancer, Volume 139Author(s): Gabriella Ferrandina, Aristei Cynthia, Biondetti Pietro Raimondo, Cananzi Ferdinando Carlo Maria, Casali Paolo, Ciccarone Francesca, Colombo Nicoletta, Comandone Alessandro, Corvo’ Renzo, De Iaco Pierandrea, Dei Tos Angelo Paolo, Donato Vittorio, Fiore Marco, Franchi Massimo, Gadducci Angiolo, Gronchi Alessandro, Guerriero Stefano, Infante Amato, Odicino Franco, Pirronti Tommaso
Wed Sep 30, 2020 14:22
Publication date: November 2020Source: European Journal of Cancer, Volume 139Author(s): Koji Matsuo, Yongmei Huang, Shinya Matsuzaki, Maximilian Klar, Jason D. Wright
Wed Sep 30, 2020 14:22
Publication date: November 2020Source: European Journal of Cancer, Volume 139Author(s): Andrew DJ. Pearson, Kimberly Stegmaier, Franck Bourdeaut, Gregory Reaman, Delphine Heenen, Michael L. Meyers, Scott A. Armstrong, Patrick Brown, Daniel De Carvalho, Nada Jabado, Lynley Marshall, Miguel Rivera, Malcolm Smith, Peter C. Adamson, Amy Barone, Christian Baumann, Samuel Blackman, Vickie Buenger, Martha Donoghue, Aundrietta D. Duncan
Wed Sep 30, 2020 14:22
Publication date: November 2020Source: European Journal of Cancer, Volume 139Author(s): Samy Belkaid, Mathilde Berger, Mathilde Nouvier, Cécile Picard, Stéphane Dalle
Wed Sep 30, 2020 14:22
Three-dimensional visualization and measurement of myopectineal orifice in non-inguinal hernia patients. Surg Radiol Anat. 2020 Sep 29;: Authors: Song Z, Yang D, Wang Y, Bu X, Yang J, Wu J, Nie X, Song H, Gu Y Abstract PURPOSE: The myopectineal orifice (MPO) is a weak area at lower part of the anterior abdominal wall that directly determines the mesh size required in inguinal hernia repair. However, MPO data have mainly been acquired from measurements...
Wed Sep 30, 2020 14:23
Initial Evaluation of Rapid, Direct-to-Digital Prostate Biopsy Pathology. Arch Pathol Lab Med. 2020 Sep 29;: Authors: Torres R, Olson E, Homer R, Martin DT, Levene MJ, Perincheri S, Sprenkle PC, Humphrey PA Abstract CONTEXT.—: Pathologist interobserver discordance is significant in grading of prostate cancer, limiting reliability. Diagnostic reproducibility may be improved with digital images, but adoption faces workflow, cost, and quality...
Wed Sep 30, 2020 14:25
CD20-Negative Nodular Lymphocyte-Predominant Hodgkin Lymphoma: A 20-Year Consecutive Case Series From a Tertiary Cancer Center. Arch Pathol Lab Med. 2020 Sep 29;: Authors: Menke JR, Spinner MA, Natkunam Y, Warnke RA, Advani RH, Gratzinger DA Abstract CONTEXT.—: Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare, indolent Hodgkin lymphoma subtype with distinct clinicopathologic features and treatment paradigms. The neoplastic...
Wed Sep 30, 2020 14:25
The Role of T-box Transcription Factor in a Pituitary Adenoma Diagnostic Algorithm. Arch Pathol Lab Med. 2020 Sep 29;: Authors: McDonald WC, McDonald KN, Helmer JA, Ho B, Wang A, Banerji N Abstract CONTEXT.—: We previously examined pituitary adenomas with immunohistochemical (IHC) stains for steroidogenic factor 1, Pit-1, anterior pituitary hormones, cytokeratin CAM 5.2, and the α-subunit of human chorionic gonadotropin and found that a screening...
Wed Sep 30, 2020 14:25
Related Articles Intranasal delivery of SDF-1α-preconditioned bone marrow mesenchymal cells improves remyelination in the cuprizone-induced mouse model of multiple sclerosis. Cell Biol Int. 2020 Feb;44(2):499-511 Authors: Beigi Boroujeni F, Pasbakhsh P, Mortezaee K, Pirhajati V, Alizadeh R, Aryanpour R, Madadi S, Ragerdi Kashani I Abstract Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous system (CNS)...
Wed Sep 30, 2020 14:29
Targeting Liver Cancer Stem Cells: An Alternative Therapeutic Approach for Liver Cancer. Cancers (Basel). 2020 Sep 24;12(10): Authors: Lee HY, Hong IS Abstract The first report of cancer stem cell (CSC) from Bruce et al. has demonstrated the relatively rare population of stem-like cells in acute myeloid leukemia (AML). The discovery of leukemic CSCs prompted further identification of CSCs in multiple types of solid tumor. Recently, extensive...
Wed Sep 30, 2020 14:29
EUFOREA treatment algorithm for allergic rhinitis. Rhinology. 2020 Sep 29;: Authors: Hellings PW, Scadding G, Bachert C, Bjermer L, Canonica GW, Cardell LO, Carney AS, Constantinidis J, Deneyer L, Diamant Z, Durham S, Gevaert P, Harvey R, Hopkins C, Kjeldsen A, Klimek L, Lund VJ, Price D, Rimmer J, Ryan D, Roberts G, Sahlstrand-Johnson P, Salmi S, Samji M, Scadding G, Smith P, Steinsvik A, Wagenmann M, Seys S, Wahn U, Fokkens WJ Abstract Allergic...
Wed Sep 30, 2020 14:29
Publication date: Available online 29 September 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Gabriela Lopes Gama, Melania Maria Ramos de Amorim, Renan Alves da Silva Júnior, Agda Cristina de Sousa Santos, Paula Lisiane Assunção, Jousilene de Sales Tavares, Thamyris de Sales Regis, Janiele de Sales Tavares, Adriana Melo
Wed Sep 30, 2020 14:29
Publication date: Available online 29 September 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Ville Niemi-Nikkola, Eerika Koskinen, Eija Väärälä, Anna-Maija Kauppila, Mauri Kallinen, Aki Vainionpää
Wed Sep 30, 2020 14:29
Background: The spread of excitation (SOE) and auditory nerve recovery function (REC) are objective measures recorded by neural response telemetry and may interfere in cochlear implant (CI) stimulation. Objective: To analyze and correlate SOE with the refractory periods in subjects with pre- and postlingual deafness implanted with different electrode arrays. Methods: This was a retrospective study of 323 ears separated by perimodiolar or straight arrays and by pre- or postlingually deaf recipients....
Wed Sep 30, 2020 10:09
Related Articles EA promotes swallowing via activating swallowing-related motor neurons in the nucleus ambiguus. Brain Res. 2019 09 01;1718:103-113 Authors: Shi J, Ye Q, Zhao J, Liu J, Xu Z, Yi W, Xu N Abstract To observe the effect of electroacupuncture (EA) on swallowing and its underlying mechanism, 32 Sprague-Dawley (SD) rats were chose and the electrophysiology was used to detect the discharge of nucleus ambiguus (NA) after EA at CV23...
Wed Sep 30, 2020 14:31
Simplified cough test can predict the risk for pneumonia in patients with acute stroke. PLoS One. 2020;15(9):e0239590 Authors: Nakamori M, Imamura E, Kuwabara M, Ayukawa T, Tachiyama K, Kamimura T, Hayashi Y, Matsushima H, Funai M, Mizoue T, Wakabayashi S Abstract We investigated the association between the results of a simplified cough test and pneumonia onset in 226 patients with acute stroke admitted to Suiseikai Kajikawa Hospital from April...
Wed Sep 30, 2020 14:31
The COVID-19 pandemic has altered and reshaped the delivery of oral and maxillofacial surgery (OMS) over the past few months. As the USA gradually lifts restrictions and re-opens, surgeons must adjust accordingly. Therefore, the OMS Resurgence Conference: Safely Resuming Practice with a New Normal was organized for 11 May 2020 to gather and disseminate expert opinions and recommendations for OMSs to thoughtfully resume work with efficiency and safety. This manuscript offers a summary of the highlights...
Wed Sep 30, 2020 03:00
Disentangling the fibrous microenvironment: designer culture models for improved drug discovery. Expert Opin Drug Discov. 2020 Sep 29;:1-13 Authors: Ort C, Lee W, Kalashnikov N, Moraes C Abstract INTRODUCTION: Standard high-throughput screening (HTS) assays rarely identify clinically viable 'hits', likely because cells do not experience physiologically realistic culture conditions. The biophysical nature of the extracellular matrix has emerged...
Wed Sep 30, 2020 14:35
Nucleic acid therapeutics: A focus on the development of aptamers. Expert Opin Drug Discov. 2020 Sep 29;: Authors: Jain S, Kaur J, Prasad S, Roy I Abstract INTRODUCTION: . Aptamers provide exciting opportunities for the development of specific and targeted therapeutic approaches. AREAS COVERED: . In this review, the authors discuss different therapeutic options available with nucleic acids, including aptamers, focussing on similarities...
Wed Sep 30, 2020 14:35
Publication date: Available online 29 September 2020Source: Clinical TherapeuticsAuthor(s): Fatima Alzahra Al Hamed, Hazem Elewa
Wed Sep 30, 2020 14:40
Investigation of Sleep Breathing Disorders in Young Patients (Under 55 years) with Mild Stroke. J Stroke Cerebrovasc Dis. 2020 Sep 10;29(12):105263 Authors: Kisabay Ak APDA, Şeyma Sarıtaş SDA, Batum SDM, Göktalay APDT, Horasan PDGD, Selcuki PDD, Yilmaz PDH Abstract INTRODUCTION: Many patients with stroke also have sleep breathing disorders (SBD), most of which is obstructive sleep apnea (OSA). METHODS: Sixty patients with a history...
Wed Sep 30, 2020 14:41
[The current status and application strategy of perioperative glucocorticoid replacement therapy for Cushing's syndrome]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2801-2803 Authors: Lu L, Lu ZL PMID: 32988138 [PubMed - in process]
Wed Sep 30, 2020 14:49
[Effect of delayed treatment on the prognosis of breast cancer patients]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2804-2807 Authors: Wang JX, Geng CZ PMID: 32988139 [PubMed - in process]
Wed Sep 30, 2020 14:49
[The role of patent foramen ovale in various cerebrovascular diseases caused by obstructive sleep apnea]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2808-2812 Authors: He QY PMID: 32988140 [PubMed - in process]
Wed Sep 30, 2020 14:49
[The value of serum dehydroepiandrosterone sulfate in differential diagnosis of Cushing's syndrome].
[The value of serum dehydroepiandrosterone sulfate in differential diagnosis of Cushing's syndrome]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2822-2827 Authors: Liu MS, Zhang WJ, Zhu KY, Chen H, Feng WH, Zhu DL, Li P Abstract Objective: To evaluate the changes and diagnostic value of serum dehydroepiandrosterone sulfate (DHEAS) in Cushing's syndrome (CS) with different etiologies. Methods: The study retrospectively recruited patients diagnosed...
Wed Sep 30, 2020 14:49
[Clinical characteristics of primary aldosteronism with concurrent adrenal Cushing's syndrome]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2828-2833 Authors: Guo JC, Chen XY, Zhang JQ, Guo XH Abstract Objective: To analyze and summarize the clinical characteristics of primary aldosteronism (PA) with concurrent adrenal Cushing's syndrome (ACS). Methods: The clinical, imaging and pathological data of 87 patients with PA admitted to Peking University...
Wed Sep 30, 2020 14:49
[Clinical features and outcomes of surgical versus conservative management in patients with subclinical Cushing's syndrome]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2834-2840 Authors: Liu MS, Zhang WJ, Zhu KY, Feng WH, Huang H, Zhu DL, Li P Abstract Objective: To examine the clinical characteristics and metabolic features of subclinical Cushing's syndrome (SCS), and determine the effects of surgical or conservative approaches on the hormone...
Wed Sep 30, 2020 14:49
[Effect of risperidone on prepulse inhibition of the startle reflex and P50 deficit in patients with first-episode and chronic schizophrenia]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2841-2845 Authors: Yu B, Zhao JX, Shi B, Zhu YH, Chen C Abstract Objective: To investigate the effect of antipsychotic medicine risperidone on prepulse inhibition of the startle reflex (PPI) and P50 deficit in patients with first-episode and chronic. Methods:...
Wed Sep 30, 2020 14:49
[Expression of PD-1, TIM-3, LAG-3 and BTLA in diffuse large B-cell lymphoma and its effect on prognosis]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2846-2853 Authors: Liu XY, Yuan XL, Ma RJ, Xu H, Yang SW, Nie L, Zhang L, Hu AX, Li Z, Zhu ZM Abstract Objective: To investigate the expression levels of programmed death protein 1 (PD-1)、T cell immunoglobulin domain and mucin domain 3(TIM-3)、lymphocyte activating gene 3 (LAG-3) and B and T lymphocyte...
Wed Sep 30, 2020 14:49
[Clinical analysis of minimal invasive surgical treatment for pancreatic neuroendocrine tumors]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2854-2857 Authors: Zhu QC, Jin WW, Mou YP, Zhou YC, Wang YY, Xia T, Lu C Abstract Objective: To analyze the safety and effectiveness of minimal invasive surgery treating pancreatic neuroendocrine tumors (pNETs), and to summarize surgical characteristics and share experience. Methods: The clinical data...
Wed Sep 30, 2020 14:49
[Clinical analysis of robot-assisted laparoscopic transabdominal preperitoneal inguinal hernia repair]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2858-2860 Authors: Liu J, Savu M, Zhi YH, Ran B, Xiao HT, Guo YF Abstract Objective: To explore the clinical value of robot-assisted laparoscopic transabdominal preperitoneal (TAPP) inguinal hernia repair. Methods: We performed a retrospective review of 23 consecutive patients who underwent robotic...
Wed Sep 30, 2020 14:49
[The prevalence of Crohn's disease based on the basic medical insurance system for urban employees in China in 2013]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2861-2866 Authors: Yang H, Zhou RN, Qian JM, Li H, Wang L Abstract Objective: To investigate the prevalence of Crohn's disease (CD) among urban employees in 24 provinces (municipalities and autonomous regions) in China in 2013. Method: The crude annual prevalence of CD among urban...
Wed Sep 30, 2020 14:49
Publication date: Available online 29 September 2020Source: European Journal of Surgical OncologyAuthor(s): Antonio Sommariva, Luca Ansaloni, Gian Luca Baiocchi, Stefano Cascinu, Roberto Cirocchi, Federico Coccolini, Marcello Deraco, Gianmaria Fiorentini, Roberta Gelmini, Andrea Di Giorgio, Piero Vincenzo Lippolis, Enrico Maria Pasqual, Cinzia Sassaroli, Antonio Macrì, Paolo Sammartino, Stefano Scaringi, Mario Valle, Marco Vaira
Wed Sep 30, 2020 14:50
Publication date: Available online 29 September 2020Source: European Journal of Surgical OncologyAuthor(s): M. Feretis, Y. Wang, B. Zhang, S.-S. Liau
Wed Sep 30, 2020 14:50
Publication date: Available online 29 September 2020Source: European Journal of Surgical OncologyAuthor(s): Tomohiro F. Nishijima, Taito Esaki, Masaru Morita, Yasushi Toh
Wed Sep 30, 2020 14:50
Publication date: Available online 30 September 2020Source: European Journal of Surgical OncologyAuthor(s): L.C. Franken, F.A. Vuijk, E.C. Soer, E. Roos, J.I. Erdmann, G.K.J. Hooijer, A.L. Vahrmeijer, S.S. Gambhir, T.M. van Gulik, A. Farina Sarasqueta, J. Verheij, R.J. Swijnenburg
Wed Sep 30, 2020 14:50
Publication date: Available online 29 September 2020Source: Médecine & DroitAuthor(s): Alice Milon, Renaud Bouvet
Wed Sep 30, 2020 14:51
Publication date: Available online 30 September 2020Source: Médecine & DroitAuthor(s): François Van Maris, Gaëtan Prissette, Cécile Manaouil
Wed Sep 30, 2020 14:51
Publication date: Available online 30 September 2020Source: Médecine & DroitAuthor(s): Khaled Annabi, Elyes Turki, Amal Ben Daly, Mohamed Ben Dhiab
Wed Sep 30, 2020 14:51
We retrospectively evaluated five maternal mortality cases that occurred in our institution within the last 10 years. Rate of maternal mortality was 24.5 per 100000 live births. Maternal mortality causes were cardiopulmonary failure secondary to veno-occlusive disease, septic shock secondary to osteosarcoma, pulmonary thromboembolism secondary to metastatic breast cancer, septic shock secondary to cholecystitis, and postpartum hemorrhage secondary to Niemann–Pick disease. Four out of five cases were...
Wed Sep 30, 2020 13:20
Introduction: Marine-Lenhart syndrome (MLS) is now understood to be a combination of Graves’ disease and autonomously functioning thyroid nodule(s) (AFTNs). The prevalence of the syndrome and suitable treatments for those living in iodine-sufficient areas are uncertain. Objectives: We aimed to investigate the prevalence, treatment, and prognosis of MLS in Japan, an iodine-sufficient area. Methods: This study involved patients who visited our hospital between February 2005 and August 2019. Among patients...
Wed Sep 30, 2020 09:32
Introduction: Numbers of thyroidectomies and awareness of postoperative quality measures have both increased. Potential sex-specific variations in clinical outcomes of patients undergoing thyroidectomy are controversial. Objective: The aim of this study was to investigate sex-specific differences in outcomes following thyroidectomy. Methods: This is a population-based cohort study of all adult patients undergoing either hemi- or total thyroidectomy in Switzerland from 2011 to 2015. The primary outcome...
Wed Sep 30, 2020 10:07
Abstract When perceiving emotional facial expressions there is an automatic tendency to react with a matching facial expression. A classic explanation of this phenomenon, termed the matched motor hypothesis, highlights the importance of topographic matching, that is, the correspondence in body parts, between perceived and produced actions. More recent studies using mimicry paradigms have challenged this classic account, producing ample evidence against the matched motor hypothesis. However, research...
Wed Sep 30, 2020 13:45
Abstract Previous research has revealed that a supine body posture, as compared to a sitting upright posture, decreases approach motivation and cognitive dissonance reduction. The present research was designed to test whether a supine body posture would decrease cognitive conflict processing, the process that occurs prior to cognitive dissonance reduction. Previous research using the Stroop task has found event‐related potentials (N450, error‐related negativity [ERN]) that are associated with cognitive...
Wed Sep 30, 2020 13:46
Abstract While self‐identity recognition has been largely explored, less is known on how self‐identity changes as a function of time. The present work aims to explore the influence of the temporal perspective on self‐identity by studying event‐related brain potentials (ERP) associated with face processing. To this purpose, participants had to perform a recognition task in two blocks with different task demands: (i) identity recognition (self, close‐friend, unknown), and (ii) life stage recognition...
Wed Sep 30, 2020 13:49
Sexual selection has long been known to favor the evolution of mating behaviors such as mate preference and competition, and to affect their genetic architecture, for instance by favoring genetic correlation between some traits. Reciprocally, genetic architecture can affect the expression and the evolvability of traits and mating behaviors. But sexual selection is highly context-dependent, making interactions between individuals a central process in evolution, governing the transmission of genotypes...
Wed Sep 30, 2020 03:00
Resting Respiratory Resistance in Female Teenage Athletes With and Without Exercise-Induced Laryngeal Obstruction. J Voice. 2020 Sep 25;: Authors: Solomon NP, Pham A, Gallena S, Johnson AT, Vossoughi J, Faroqi-Shah Y Abstract OBJECTIVE: Exercise-induced laryngeal obstruction (EILO) occurs with paradoxical vocal fold motion or supraglottic collapse during moderate to vigorous exercise. Previously, Gallena et al (2015) reported lower-than-normal...
Wed Sep 30, 2020 15:18
Steam and/or Semi-occluded Vocal Tract Exercise as Morning Vocal Warm-up Strategy. J Voice. 2020 Sep 25;: Authors: Keltz A, McHenry M Abstract OBJECTIVE: This study was designed to evaluate the effectiveness of either steam, semi-occluded vocal tract (SOVT) exercises, or a combination of both as a speaking voice warm-up strategy to be used at the start of the day. METHODS/DESIGN: This prospective study assessed the impact of three...
Wed Sep 30, 2020 15:18
Related Articles UV Inactivation of Rotavirus and Tulane Virus Targets Different Components of the Virions. Appl Environ Microbiol. 2020 02 03;86(4): Authors: Araud E, Fuzawa M, Shisler JL, Li J, Nguyen TH Abstract Enteric viruses are shed in fecal material by humans and other animals and are common contaminants in wastewater and surface water. Wastewater treatment plants often disinfect this effluent with low-pressure and medium-pressure...
Wed Sep 30, 2020 15:18
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c08600
Tue Sep 29, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07027
Wed Sep 30, 2020 07:00
Rab GTPases in the differential processing of phagocytosed pathogens versus efferocytosed apoptotic cells. Histol Histopathol. 2020 Sep 29;:18252 Authors: Taefehshokr N, Yin C, Heit B Abstract Phagocytosis is an important feature of innate immunity in which invading microorganisms are engulfed, killed and degraded - and in some immune cells, their antigens presented to adaptive immune system. A closely related process, efferocytosis, removes...
Wed Sep 30, 2020 15:22
Background: Leber hereditary optic neuropathy (LHON) leads to bilateral central vision loss. In a clinical trial setting, idebenone has been shown to be safe and to provide a trend toward improved visual acuity, but long-term evidence of effectiveness in real-world clinical practice is sparse. Methods: Open-label, multicenter, retrospective, noncontrolled analysis of long-term visual acuity and safety in 111 LHON patients treated with idebenone (900 mg/day) in an expanded access program....
Wed Sep 23, 2020 03:00
No abstract available
Wed Sep 23, 2020 03:00
Background: This study identifies the diagnostic errors leading to misdiagnosis of 3rd nerve palsy and to aid clinicians in making this diagnosis. The objective of this article is to determine the incidence of misdiagnosis of 3rd cranial nerve palsy (3rd nerve palsy) among providers referring to a tertiary care neuro-ophthalmology clinic and to characterize diagnostic errors that led to an incorrect diagnosis. Methods: This was a retrospective clinic-based multicenter cross-sectional...
Wed Sep 23, 2020 03:00
No abstract available
Wed Sep 23, 2020 03:00
Purpose: The risk/benefit-ratio of deep brain stimulation (DBS) depends on focusing the electrical field onto the target volume, excluding side-effect eliciting structures. Directional leads limiting radial current diffusion can target stimulation but add a spatial degree of freedom that requires control to align multimodal imaging datasets and for anatomical interpretation of stimulation. Unpredictable postoperative lead rotations have been reported. The extent and timing of rotation from the surgically...
Wed Sep 30, 2020 12:20
Publication date: Available online 29 September 2020Source: BrachytherapyAuthor(s): Leonid B. Reshko, Jeremy T. Gaskins, Daniel S. Metzinger, Sarah L. Todd, Harriet B. Eldredge-Hindy, Scott R. Silva
Wed Sep 30, 2020 15:31
Publication date: Available online 30 September 2020Source: BrachytherapyAuthor(s): Arun Elangovan, Siraj Husain, Philip McGeahy, Michael Roumeliotis, Che Hsuan David Wu, Nathan Wolfe, Tyler Meyer, Elizabeth Watt, Kevin Martell, Kundan Thind
Wed Sep 30, 2020 15:31
No Cases of Nephrogenic Systemic Fibrosis after Administration of Gadoxetic Acid. Radiology. 2020 Sep 29;:200788 Authors: Starekova J, Bruce RJ, Sadowski EA, Reeder SB Abstract Background Gadoxetic acid (GA) has distinctive pharmacokinetic properties with important applications in hepatobiliary imaging. However, there are limited data evaluating the safety of GA administration in patients with impaired kidney function and the incidence of nephrogenic...
Wed Sep 30, 2020 15:39
Interobserver Variability and Diagnostic Performance of Gadoxetic Acid-enhanced MRI for Predicting Microvascular Invasion in Hepatocellular Carcinoma. Radiology. 2020 Sep 29;:201940 Authors: Min JH, Lee MW, Park HS, Lee DH, Park HJ, Lim S, Choi SY, Lee J, Lee JE, Ha SY, Cha DI, Carriere KC, Ahn JH Abstract Background Accurate identification of microvascular invasion (MVI) in hepatocellular carcinoma (HCC) before treatment is critical for selecting...
Wed Sep 30, 2020 15:39
Detecting Large Vessel Occlusion at Multiphase CT Angiography by Using a Deep Convolutional Neural Network. Radiology. 2020 Sep 29;:200334 Authors: Stib MT, Vasquez J, Dong MP, Kim YH, Subzwari SS, Triedman HJ, Wang A, Wang HC, Yao AD, Jayaraman M, Boxerman JL, Eickhoff C, Cetintemel U, Baird GL, McTaggart RA Abstract Background Large vessel occlusion (LVO) stroke is one of the most time-sensitive diagnoses in medicine and requires emergent...
Wed Sep 30, 2020 15:39
Observer Performance for Detection of Pulmonary Nodules at Chest CT over a Large Range of Radiation Dose Levels. Radiology. 2020 Sep 29;:200969 Authors: Fletcher JG, Levin DL, Sykes AG, Lindell RM, White DB, Kuzo RS, Suresh V, Yu L, Leng S, Holmes DR, Inoue A, Johnson MP, Carter RE, McCollough CH Abstract Background There is a wide variation in radiation dose levels that can be used with chest CT in order to detect indeterminate pulmonary nodules....
Wed Sep 30, 2020 15:39
Accurate Assessment of Vascularity of Focal Hepatic Lesions in Arterial Phase Imaging. Radiology. 2020 Sep 29;:202780 Authors: Wang F, Numata K, Ruan L PMID: 32990515 [PubMed - as supplied by publisher]
Wed Sep 30, 2020 15:39
Metabolite signature of albuminuria involves amino acid pathways in 8,661 Finnish men without diabetes. J Clin Endocrinol Metab. 2020 Sep 29;: Authors: Fernandes Silva L, Vangipurapu J, Smith U, Laakso M Abstract OBJECTIVE: To investigate metabolite signature of albuminuria in individuals without diabetes or chronic kidney disease to identify possible mechanisms resulting in increased albuminuria and elevated risk of T2D. RESEARCH...
Wed Sep 30, 2020 15:39
Related Articles Renal Excretion of Contrast on CT Myelography: A Specific Marker of CSF Leak. AJNR Am J Neuroradiol. 2020 02;41(2):351-356 Authors: Behbahani S, Raseman J, Orlowski H, Sharma A, Eldaya R Abstract BACKGROUND AND PURPOSE: The purpose of this study was to evaluate the sensitivity and specificity of renal/ureteric opacification on postmyelographic CT as a sign of CSF leak. MATERIALS AND METHODS: We performed a retrospective...
Wed Sep 30, 2020 15:42
Abstract Historians and biologists identify the debate between mechanists and vitalists over the nature of life itself with the arguments of Driesch, Loeb, and other prominent voices. But what if the conversation was broader and the consequences deeper for the field? Following the suspicions of Joseph Needham in the 1930s and Francis Crick in the 1960s, we deployed tools of the digital humanities to an old problem in the history of biology. We analyzed over 31,000 peer-reviewed...
Wed Sep 30, 2020 03:00
EUFOREA treatment algorithm for allergic rhinitis. Rhinology. 2020 Sep 29;: Authors: Hellings PW, Scadding G, Bachert C, Bjermer L, Canonica GW, Cardell LO, Carney AS, Constantinidis J, Deneyer L, Diamant Z, Durham S, Gevaert P, Harvey R, Hopkins C, Kjeldsen A, Klimek L, Lund VJ, Price D, Rimmer J, Ryan D, Roberts G, Sahlstrand-Johnson P, Salmi S, Samji M, Scadding G, Smith P, Steinsvik A, Wagenmann M, Seys S, Wahn U, Fokkens WJ Abstract Allergic...
Wed Sep 30, 2020 15:46
The ubiquity of recombination (and sex) in nature has defied explanation since the time of Darwin. Conditions that promote their evolution, however, are well-understood and arise when genomes contain more selectively mismatched combinations of alleles than can be explained by chance alone. Recombination remedies this imbalance by shuffling alleles across individuals. The great difficulty in explaining the ubiquity of recombination in nature lies in identifying a source of this imbalance that is comparably...
Wed Sep 30, 2020 03:00
Globally, colorectal cancer (CRC) affects more than 1 million people each year. In addition to non-modifiable and other environmental risk factors, Fusobacterium nucleatum infection has been linked to CRC recentl...
Tue Sep 29, 2020 03:00
N6-Methyladenosine (m6A) modification has been implicated in multiple processes for colon cancer development. IGF2BP3 was a newly reported m6A reader, whereas its role in colon cancer remains unclear.
Tue Sep 29, 2020 03:00
Publication date: Available online 29 September 2020Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Jia Xu, Zin Mar Aung, Sousan Cheong, Taeho Won, Ruhong Zhang, Feng Xu, Jiajun Fan, Dong Han
Wed Sep 30, 2020 15:49
Liquid biopsy for ALK-positive early non-small-cell lung cancer predicts disease relapse. Future Oncol. 2020 Sep 29;: Authors: Li J, Dong W, Liu LN, Huang YJ, Xiao MF Abstract Background: We aimed to determine whether circulating tumor cells (CTCs) and cell-free DNA (cfDNA) aids in prognosis of relapse-free survival (RFS). Methods: Non-small cell lung cancer patients with ALK mutations were recruited prospectively. CTCs and cfDNA were quantified...
Wed Sep 30, 2020 15:53
Fanconi–Bickel syndrome is an autosomal recessive disorder of glucose metabolism. It is an extremely rare disorder. Most cases have been reported in consanguineous communities. None of the cases have been repo...
Wed Sep 30, 2020 03:00
Abstract Objective Individuals with autism spectrum disorder (ASD) participate in less physical activity (PA) and more sedentary behavior than their peers without ASD. Methods The study employed Chi-square analyses of the NSCH 2016–2017 data to compare PA, TV/video watching/gaming, and usage of portable electronic devices by children with and without...
Wed Sep 30, 2020 03:00
Related Articles Enhancing nodular lesions in Chiari II malformations in the setting of persistent hindbrain herniation: case report and literature review. Childs Nerv Syst. 2019 07;35(7):1239-1243 Authors: Semonche A, Shah AH, Eichberg DG, Gultekin SH, Komotar RJ, Ivan ME Abstract BACKGROUND: Chiari II malformation includes concomitant cerebellar tonsillar herniation, hydrocephalus, and myelomeningocele. Rarely, pediatric patients with persistent...
Wed Sep 30, 2020 16:10
Craniopharyngiomas: Challenges and Controversies. World Neurosurg. 2020 Oct;142:593-600 Authors: Asha MJ, Oswari S, Takami H, Velasquez C, Almeida JP, Gentili F Abstract Despite its benign histopathology, the treatment of craniopharyngioma remains one of the most formidable challenges faced by skull base surgeons. The technical challenges of tackling these complex central skull base lesions are paralleled by clinical challenges related to their...
Wed Sep 30, 2020 16:10
Surgical Anatomy Applied to the Resection of Craniopharyngiomas: Anatomic Compartments and Surgical Classifications. World Neurosurg. 2020 Oct;142:611-625 Authors: Almeida JP, Workewych A, Takami H, Velasquez C, Oswari S, Asha M, Bernardo A, Gentili F Abstract BACKGROUND: Resective surgery remains the main treatment option for most patients with craniopharyngiomas. Understanding of the microsurgical anatomy of the sella and suprasellar region...
Wed Sep 30, 2020 16:10
Pediatric Basilar Skull Fracture Mechanisms and Trends From 2007 to 2018. Otolaryngol Head Neck Surg. 2020 Sep 29;:194599820960727 Authors: Magit A, Stramiello JA, Good R, Nation J Abstract OBJECTIVES: To evaluate the specific mechanism and trend of injury resulting in pediatric basilar skull fractures. STUDY DESIGN: Retrospective chart review of a trauma database. SETTING: Tertiary care children's hospital. METHODS:...
Wed Sep 30, 2020 16:10
Design of a temporoparietal fascial flap after a spontaneous nasal fistula unresolved by conventional approaches. Neurocirugia (Astur). 2020 Sep 25;: Authors: Escalante Encinas W, Landini Lutaif Dolci R, Castellari Burchianti L, Bossi Todeschini A, Leite Dos Santos AR, Lazarini PR, Esteves Veiga JC Abstract We report the surgical management of a spontaneous and recurrent nasal fistula using a temporoparietal fascial flap for definitive treatment...
Wed Sep 30, 2020 16:10
Quality-of-life evaluation for patients submitted to nasal endoscopic surgery for resection of pituitary tumours. Eur Arch Otorhinolaryngol. 2020 Sep 28;: Authors: Dolci RLL, de Moraes LT, de Carvalho ACM, Rickli JCK, de Souza JL, Encinas WE, Junior JVL, Scalissi NM, Dos Santos ARL, Lazarini PR Abstract PURPOSE: This study aimed to evaluate the pre- and post-operative quality-of-life of patients submitted to the resection of pituitary adenoma...
Wed Sep 30, 2020 16:10
How I do it: retrosigmoid intradural inframeatal petrosectomy. Acta Neurochir (Wien). 2020 Sep 28;: Authors: Meling TR, Zegarek G, Schaller K Abstract BACKGROUND: Lesions infiltrating the petrous temporal bone are some of the most complex to treat surgically. Many approaches have been developed in order to address these lesions, including endoscopic endonasal, anterior petrosectomy, posterior petrosectomy, and retrosigmoid. METHOD:...
Wed Sep 30, 2020 16:10
Polymicrobial Skull Base Osteomyelitis Related to Chronic Sphenoiditis and Endoscopic Sinus Surgery.
Polymicrobial Skull Base Osteomyelitis Related to Chronic Sphenoiditis and Endoscopic Sinus Surgery. Laryngoscope. 2020 Sep 29;: Authors: Shellman Z, Coates M, Kara N Abstract Skull base osteomyelitis (SBO) secondary to endoscopic surgery for chronic sinusitis and post-operative sphenopalatine artery electrocautery has not been previously reported. This case report details an instance of Central SBO with an unusual microbiology profile and...
Wed Sep 30, 2020 16:10
EUFOREA treatment algorithm for allergic rhinitis. Rhinology. 2020 Sep 29;: Authors: Hellings PW, Scadding G, Bachert C, Bjermer L, Canonica GW, Cardell LO, Carney AS, Constantinidis J, Deneyer L, Diamant Z, Durham S, Gevaert P, Harvey R, Hopkins C, Kjeldsen A, Klimek L, Lund VJ, Price D, Rimmer J, Ryan D, Roberts G, Sahlstrand-Johnson P, Salmi S, Samji M, Scadding G, Smith P, Steinsvik A, Wagenmann M, Seys S, Wahn U, Fokkens WJ Abstract Allergic...
Wed Sep 30, 2020 16:10
Extracranial-Intracranial Bypass as Primary Treatment for Internal Carotid Artery Blood Blister-Like Aneurysms, Not Just a Last Resort. World Neurosurg. 2020 Sep 26;: Authors: Richardson AM, Baskaya MK PMID: 32992064 [PubMed - as supplied by publisher]
Wed Sep 30, 2020 16:10
Chronic rhinosinusitis (CRS) negatively affects quality of life (QoL), and balloon catheter sinuplasty (BCS) has shown good outcomes in adult patients. However, there has not been much research on the effects ...
Tue Sep 29, 2020 03:00
Incidence, Pathophysiology, and Impact of Coronavirus Disease 2019 (COVID-19) on Acute Ischemic Stroke. World Neurosurg. 2020 Oct;142:523-525 Authors: Majmundar N, Ducruet A, Prakash T, Nanda A, Khandelwal P PMID: 32987584 [PubMed - in process]
Wed Sep 30, 2020 16:20
Coronavirus Disease 2019 (COVID-19) Response Measures-A Singapore Neurosurgical Academic Medical Center Experience in Emerging from the Worldwide Pandemic. World Neurosurg. 2020 Oct;142:526-527 Authors: Lim JX, Leong AZ, Tan CH, Teo K, Nga VDW, Lwin S, Chou N, Yeo TT PMID: 32987585 [PubMed - in process]
Wed Sep 30, 2020 16:20
Transcript of WORLD NEUROSURGERY Twitter Chat with Walter Jean, M.D., hosted by Aliyu Ndajiwo, M.D., May 30, 2020 at 20:00 GMT. World Neurosurg. 2020 Oct;142:528-531 Authors: Jean W, Ndajiwo A PMID: 32987586 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding "Association Between Facility Volume and Overall Survival for Patients with Grade II Meningioma after Gross Total Resection". World Neurosurg. 2020 Oct;142:537 Authors: Lordelo GC, Nespoli VS, Neville IS, Paiva WS PMID: 32987587 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding "Contralateral Vasospasm in an Uncomplicated Elective Anterior Communicating Artery Aneurysm Clipping". World Neurosurg. 2020 Oct;142:538-539 Authors: Aruta G, Ceraudo M, Truffelli M, Fiaschi P PMID: 32987588 [PubMed - in process]
Wed Sep 30, 2020 16:20
In Reply to the Letter to the Editor Regarding "Contralateral Vasospasm in an Uncomplicated Elective Anterior Communicating Artery Aneurysm Clipping". World Neurosurg. 2020 Oct;142:540 Authors: Bigder MG, Steinberg GK PMID: 32987589 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding: "Three-Dimensional Virtual Intraoperative Reconstruction: A Novel Method to Explore a Virtual Neurosurgical Field". World Neurosurg. 2020 Oct;142:543 Authors: Salmas M, Chytas D, Paraskevas G, Noussios G, Skandalakis GP, Troupis T PMID: 32987590 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding "Does the Setting of External Ventricular Drain Placement Affect Morbidity? A Systematic Literature Review Comparing Intensive Care Unit versus Operating Room Procedures". World Neurosurg. 2020 Oct;142:544-545 Authors: Abdallah A PMID: 32987591 [PubMed - in process]
Wed Sep 30, 2020 16:20
In Reply to the Letter to the Editor Regarding "Does the Setting of External Ventricular Drain Placement Affect Morbidity? A Systematic Literature Review Comparing Intensive Care Unit versus Operating Room Procedures". World Neurosurg. 2020 Oct;142:546-547 Authors: Dawod G, Caras A, Henkel N, Karim N, Qaqish H, Mugge L, Medhkour A PMID: 32987592 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding 'Surgical Treatment of Secondary Trigeminal Neuralgia Induced by Cerebellopontine Angle Tumors: A Single-Center Experience'. World Neurosurg. 2020 Oct;142:548-549 Authors: Gosal JS, Das KK, Khatri D, Jaiswal A, Behari S PMID: 32987593 [PubMed - in process]
Wed Sep 30, 2020 16:20
In Reply to the Letter to the Editor Regarding "Surgical Treatment of Secondary Trigeminal Neuralgia Induced by Cerebellopontine Angle Tumors: A Single-Center Experience". World Neurosurg. 2020 Oct;142:550 Authors: Zhang YQ, Yu F, Zhao ZY, Men XZ, Shi W PMID: 32987594 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding "Recurrent Spinal Intramedullary Arachnoid Cysts". World Neurosurg. 2020 Oct;142:554 Authors: Aljameely A, Baeesa SS PMID: 32987595 [PubMed - in process]
Wed Sep 30, 2020 16:20
In Reply to the Letter to the Editor Regarding "Recurrent Spinal Intramedullary Arachnoid Cyst: Case Report and Literature Review". World Neurosurg. 2020 Oct;142:555 Authors: Miyashita K, Ichinose T PMID: 32987596 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding "Failure of Surgery in Idiopathic Spinal Cord Herniation: Case Report and Review of the Literature". World Neurosurg. 2020 Oct;142:556-557 Authors: Shimizu S PMID: 32987597 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding: "Usefulness of 3D Printed Models in the Management of Complex Craniovertebral Junction Anomalies: Choice of Treatment Strategy, Design of Screw Trajectory, and Protection of Vertebral Artery." World Neurosurg. 2020 Oct;142:558 Authors: Salmas M, Chronopoulos E, Nikolaou VS, Babis GC, Kaseta MK, Skandalakis GP, Chytas D PMID: 32987598 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor: "The Neurosurgeon and Medical Professionalism During the COVID-19 Pandemic". World Neurosurg. 2020 Oct;142:559-560 Authors: Bohórquez-Rivero J, García-Ballestas E, Moscote-Salazar LR PMID: 32987599 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding "Incidence of Acute Ischemic Stroke and Rate of Mechanical Thrombectomy During the COVID-19 Pandemic in a Large Tertiary Care Telemedicine Network". World Neurosurg. 2020 Oct;142:561-562 Authors: McClain JV, Chance EA, Polcha GM PMID: 32987600 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding "Delayed Contralateral Trigeminal Neuralgia after Microvascular Decompression and Postoperative Changes in Venous Outflow". World Neurosurg. 2020 Oct;142:563 Authors: Ge Y, Lai Q, Xu X PMID: 32987601 [PubMed - in process]
Wed Sep 30, 2020 16:20
In Reply to the Letter to the Editor Regarding "Delayed Contralateral Trigeminal Neuralgia After Microvascular Decompression and Postoperative Change in Venous Outflow". World Neurosurg. 2020 Oct;142:564 Authors: Eibach S, Steinfort B, Di Ieva A PMID: 32987602 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to Editor Regarding: "Decrease in Neurosurgical Program Volume During COVID-19: Residency Programs Must Adapt". World Neurosurg. 2020 Oct;142:565 Authors: Murlimanju BV, Shrivastava A, Moscote-Salazar LR, Rahman MM, Agrawal A PMID: 32987603 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor: COVID-19 & Neurosurgical Training in Low- and Middle-Income Countries. World Neurosurg. 2020 Oct;142:566-568 Authors: Kanmounye US, Ammar A, Esene I, El Ouahabi A, Park K PMID: 32987604 [PubMed - in process]
Wed Sep 30, 2020 16:20
Letter to the Editor Regarding "Awake Craniotomy in a Patient with Previously Diagnosed Post-Traumatic Stress Disorder". World Neurosurg. 2020 Oct;142:569 Authors: Damara FA, Ramdhani AN, Channel IC, Anton PMID: 32987605 [PubMed - in process]
Wed Sep 30, 2020 16:20
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