Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Τρίτη 29 Νοεμβρίου 2022

Determining Invasion Depth in Superficial Pharyngeal Carcinoma by Transoral Ultrasonography

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Determining Invasion Depth in Superficial Pharyngeal Carcinoma by Transoral Ultrasonography

Classification for transoral US findings. (A) US-EP. (B) US-SEP slight. (C) US-SEP deep. White arrow: Tumor. EP, epithelium; SEP, subepithelial propria; US, ultrasonography.


Objectives

To examine the clinical usefulness of transoral ultrasonography (US) in determining the invasion depth of superficial pharyngeal carcinoma (SPC). Determining the invasion depth of SPC is crucial for transoral surgery including determining treatment strategy. This study aimed to examine the usefulness of transoral US in determining the invasion depth of SPC.

Methods

Forty-six patients with 51 lesions who underwent both magnifying endoscopy with narrow-band imaging (ME-NBI) and transoral US were included. The primary outcomes were the sensitivity, specificity, positive (PPV), and negative predictive values (NPV) of ME-NBI and transoral US findings for pathological tumor depth in SPCs.

Results

The accuracy (82.4%), sensitivity (85.2%), PPV (82.1%), and NPV (82.6%) rates of US for subepithelial propria (SEP) were higher than those of ME-NBI and macroscopic classification, indicating that transoral US is superior to ME-NBI in determining the invasion depth. All cases where the SEP was clearly invaded (SEP deep) could be diagnosed as SEP by transoral US.

Conclusions

Transoral US may be useful in determining the invasion depth of SPCs.

Level of Evidence

3 Laryngoscope, 2022

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