Σφακιανάκης Αλέξανδρος
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Τρίτη 20 Οκτωβρίου 2015

OtoRhinoLaryngology New Articles & Online Journals,October 20th,2015

Surgical anatomy and pathology of the middle ear

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
Surgical anatomy and pathology of the middle ear by Jan Christoffer Luers, Karl-Bernd Hüttenbrink via Journal of Anatomy Abstract Middle ear surgery is strongly influenced by anatomical and functional characteristics of the middle ear. The complex anatomy means a challenge for the otosurgeon who moves between preservation or improvement of highly important functions (hearing, balance, facial motion) and eradication of diseases. Of these, perforations of the tympanic membrane, chronic otitis media, tympanosclerosis and cholesteatoma are encountered most often in clinical practice. Mode... περισσότερα »

Determination of cIg LCs, Bcl-2 expression and PCR clonality analysis of B cells improved accuracy of cytological diagnoses in BCL with inconclusive sIg LC

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
Inconclusive flow cytometric surface light chain results; can cytoplasmic light chains, Bcl-2 expression and PCR clonality analysis improve accuracy of cytological diagnoses in B-cell lymphomas? by Andreja Brozic via Diagnostic Pathology - Latest Articles Background: Flow cytometric immunophenotyping (FCI), is widely used in cytology for distinguishing between B-cell lymphoma (BCL) and reactive lymphocytic proliferations (RLP), mainly by identifying monotypic B-cell populations. Since this cannot always be determined by ratios of surface immunoglobulin light chains (sIg LCs) we wanted...περισσότερα »

Oxycodone/Acetaminophen Versus Hydrocodone/Acetaminophen

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Comparative Analgesic Efficacy of Oxycodone/Acetaminophen Versus Hydrocodone/Acetaminophen for Short-term Pain Management in Adults Following ED Discharge by Andrew K. Chang, Polly E. Bijur, Lynne Holden, E. John Gallagher via Academic Emergency Medicine Abstract Objectives The objective was to test the hypothesis that oxycodone/acetaminophen provides superior analgesia to hydrocodone/acetaminophen for the treatment of acute extremity pain following emergency department (ED) discharge. Methods This was a prospective, randomized, double-blind clinical trial of nonelderly adult ED patie... περισσότερα »

Headache Suggestive of Subarachnoid Hemorrhage

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
An Observational Study of 2,248 Patients Presenting With Headache, Suggestive of Subarachnoid Hemorrhage, Who Received Lumbar Punctures Following Normal Computed Tomography of the Head by David Sayer, Ben Bloom, Katalin Fernando, Stuart Jones, Sally Benton, Shumontha Dev, Sathish Deverapalli, Tim Harrisvia Academic Emergency Medicine [image: cover.gif?v=1&s=e29baa70a6aa5c45834b29bf] Abstract Objectives The objective was to determine the incidence of subarachnoid hemorrhage (SAH) diagnosed by lumbar puncture (LP) when the head computed tomography (CT) was reported as demonstrating no...περισσότερα »

Modified jaw-thrust maneuver to insert laryngeal tube suction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
Modified jaw-thrust maneuver to insert laryngeal tube suctionRajesh Mahajan, Smriti Gulati, Robina Nazir, Anjali Mehta, 2015-10-20 10:41:38 AM Insertion of laryngeal tube suction–II (LTS-II; VBM Medizintechnik GmbH, Sulz a.N., Germany) may be difficult using a standard insertion technique as described by the manufacturer because of insufficient retropharyngeal space which is filled with tongue and prevents movement of LTS-II down into the esophagus. Alternatively, LTS-II may be malpositioned into the trachea or impinge on the pyriform sinus [1]. Schalk and colleagues [2] in their landmark ... περισσότερα »

Combination of videolaryngoscope and tracheal tube introducer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
for difficult infant airway management by Fumihiro Ohchi, Nobuyasu Komasawa, Kentaro Imagawa, Toshiaki Minami via Journal of Clinical Anesthesia Emergency infant airway management is challenging, especially in difficult airway cases. Here, we report a successful case of difficult infant airway management in which a videolaryngoscope was used in combination with a tracheal tube introducer to perform awake intubation.

The Journal of Immunology

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 12 δευτερόλεπτα
- In This Issue [IN THIS ISSUE]2015-10-20 10:38:11 AM Διαβάστε περισσότεραΑρχή - The Long (and Sometimes Endless) Road to Murine Lupus Genes [PILLARS OF IMMUNOLOGY]Mohan, C., 2015-10-20 10:38:11 AM Διαβάστε περισσότεραΑρχή - Pillars Article: Polygenic Control of Susceptibility to Murine Systemic Lupus Erythematosus. Immunity. 1994. 1: 219-229 [PILLARS OF IMMUNOLOGY]Morel, L., Rudofsky, U. H., Longmate, J. A., Schiffenbauer, J., Wakeland, E. K., 2015-10-20 10:38:11 AM Διαβάστε περισσότεραΑρχή - Cohabitation in the Intestine: Interactions among Helminth ...περισσότερα »

Enhancing Dendritic Cell-based Immunotherapy with IL-2/Monoclonal Antibody Complexes

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
for Control of Established Tumors [TUMOR IMMUNOLOGY] by Kim, M. T., Richer, M. J., Gross, B. P., Norian, L. A., Badovinac, V. P., Harty, J. T. via The Journal of Immunology current issue U.S. Food and Drug Administration–approved high-dose IL-2 therapy and dendritic cell (DC) immunization offer time-tested treatments for malignancy, but with defined issues of short in vivo *t*1/2, toxicity, and modest clinical benefit. Complexes of IL-2 with specific mAbs (IL-2c) exhibit improved stability in vivo with reduced toxicity and are capable of stimulating NK cell and memory phenotype CD8 T...περισσότερα »

Oral Medicine (Stomatology)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Across the Globe: Birth, Growth and Future via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 19 October 2015 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): C. Scully, C.S. Miller, J.M. Aguirre Urizar, I. Alajbeg, O.D.P. Almeida, J.V. Bagan, C. Birek, Q. Chen, C.S. Farah, J.P. Figueiredo, B. Hasséus, M. Jontell, A.R. Kerr, G. Laskaris, L. Lo Muzio, A. Mosqueda-Taylor, K.S. Nagesh, N. Nikitakis, D. Peterson, J. Sciubba, K. Thongprasom, S. Tovaru, Y. Zadik Oral Medicine (Stomatology) is a recognized an... περισσότερα »

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 17 δευτερόλεπτα
- Society Page2015-10-20 10:32:39 AM Publication date: November 2015 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 120, Issue 5 Διαβάστε περισσότεραΑρχή - Contents2015-10-20 10:32:39 AM Publication date: November 2015 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 120, Issue 5 Διαβάστε περισσότεραΑρχή - Editorial Board2015-10-20 10:32:39 AM Publication date: November 2015 *Source:*Oral Surgery, Oral Medicine, Oral Patho... περισσότερα »

Inspire® Upper Airway Stimulation (UAS)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
Inspire Upper Airway Stimulation - P130008 [image: Illustration of Inspire Upper Airway Stimulation, indicating Stimulation Lead, Inspire II Implantable Pulse Generator (IPG), and Sensing Lead.] This is a brief overview of information related to FDA's approval to market this product. See the links below to the Summary of Safety and Effectiveness Data (SSED) and product labeling for more complete information on this product, its indications for use, and the basis for FDA's approval. *Product Name:* Inspire® Upper Airway Stimulation (UAS) *PMA Applicant:* Inspire Medical Systems, Inc. *... περισσότερα »

Upper airway stimulation is an effective treatment option for obstructive sleep apnea after failure of positive airway pressure (PAP) therapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Patient selection for upper airway stimulation: is concentric collapse in sleep endoscopy predictable? via Latest Results for Sleep and Breathing AbstractPurposeUpper airway stimulation is an effective treatment option for obstructive sleep apnea after failure of positive airway pressure (PAP) therapy. To ensure a therapeutic effect, closed-loop hypoglossal nerve implants require the absence of palatal complete concentric collapse during sleep endoscopy. The frequency and potential predictors of this exclusion criterion are unknown. MethodsOver a 2-year period, 74 consecutive patients... περισσότερα »

Effectiveness of oral pressure therapy in obstructive sleep apnea

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
: a systematic analysis via Latest Results for Sleep and Breathing AbstractPurposeOral pressure therapy (OPT) has emerged as a novel technique to treat obstructive sleep apnea (OSA) in the past few years. Given this is a relatively new treatment approach, currently, little is known with respect to its clinical utility. The aim of this review was to explore the success rate of OPT when used to treat OSA. MethodsPubMed, MEDLINE, Scopus, Web of Science, and the Cochrane Library databases were searched for pertinent studies. ResultsThe OPT treatment success rates varied widely between 25 a... περισσότερα »

Melanoma Research

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Melanoma Research - Current Issue - The conquest of melanoma by immunotherapyLejeune, Ferdy J., 2015-10-01 07:00:00 AM No abstract available Διαβάστε περισσότεραΑρχή - A combination of high dose rate (10X FFF/2400 MU/min/10 MV X-rays) and total low dose (0.5 Gy) induces a higher rate of apoptosis in melanoma cells in vitro and superior preservation of normal melanocytesSarojini, Sreeja; Pecora, Andrew; Milinovikj, Natasha; Barbiere, Joseph; Gupta, Saakshi; Hussain, Zeenathual M.; Tuna, Mehmet; Jiang, Jennifer; Adrianzen, Laura; Jun, Jaewook; Catello, Lau... περισσότερα »

Sleep and Breathing

Alexandros G. SfakianakisστοΥπνική Άπνοια και Διαταραχές ΎπνουΠριν από 25 δευτερόλεπτα
- Response to: Obstructive sleep apnoea and non-restorative sleep induced by the interface2015-10-19 02:00:00 AM Διαβάστε περισσότεραΑρχή - Obstructive sleep apnoea and non-restorative sleep induced by the interface2015-10-19 02:00:00 AM Διαβάστε περισσότεραΑρχή - Patient selection for upper airway stimulation: is concentric collapse in sleep endoscopy predictable?2015-10-19 02:00:00 AM AbstractPurpose Upper airway stimulation is an effective treatment option for obstructive sleep apnea after failure of positive airway pressure (PAP) therapy. To en... περισσότερα »

Circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 41 δευτερόλεπτα
Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy? via Tumor Biology AbstractLong non-coding RNAs (lncRNAs) have been shown to be aberrantly expressed in head and neck cancer (HNC). The aim of the present study was to evaluate plasma levels of three lncRNA molecules (lincRNA-p21, GAS5, and HOTAIR) in the treatment response in HNC patients treated with radical chemoradiotherapy (CRT). Forty-one patients with HNC were enrolled in the study. Most of the patients h... περισσότερα »

miR-29a suppresses growth and metastasis in papillary thyroid carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 43 δευτερόλεπτα
miR-29a suppresses growth and metastasis in papillary thyroid carcinoma by targeting AKT3 via Tumor Biology AbstractMicroRNA-29a (miR-29a) has been reported to play important roles in tumor initiation, development, and metastasis in various cancers. However, the biological function and potential mechanisms of miR-29a in papillary thyroid carcinoma (PTC) remain unclear. In the present study, we discovered that miR-29a was frequently downregulated in PTC tissues, and its expression was significantly associated with tumor size, TNM stage, and lymph node metastasis. Functional assays sho... περισσότερα »

Inactivation of hedgehog-interacting protein (HHIP) and overexpression of Gli1 play vital roles in the development of diverse human cancers

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 43 δευτερόλεπτα
The hedgehog antagonist HHIP as a favorable prognosticator in glioblastoma via Tumor Biology AbstractInactivation of hedgehog-interacting protein (HHIP) and overexpression of Gli1 play vital roles in the development of diverse human cancers. The aim of this study is to examine the association of HHIP and Gli1 with the clinicopathologic features and prognosis of patients with glioblastoma (GBM). The expression of HHIP and Gli1 in 103 patients with GBM and 32 control patients was investigated by immunohistochemistry. Statistical analysis was utilized to evaluate the association of HHIP ... περισσότερα »

The effects of a voice education program on the Vocal Handicap Index (VHI) scores of elementary school teachers

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 43 δευτερόλεπτα
Article in Press The Effects of a Voice Education Program on VHI Scores of Elementary School Teachers Maryam Faham , Akram Ahmadi[image: correspondence][image: email] , Michael Drinnan , Najme Saadatmand , Elahe Fatahi , Maryam Jalalipour Summary Introduction Teachers seem to be vulnerable to voice disorders because of excessive use of their voice. The purpose of this study was to investigate the effects of a voice education program on the Vocal Handicap Index (VHI) scores of elementary school teachers in the Persian education system. Method This was a semi-experimental study, pe... περισσότερα »

Voice Focus on Oral-Nasal Balance in Speech

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 43 δευτερόλεπτα
Influence of by Gillian de Boer, Tim Bressmann via Journal of Voice The concept of voice focus describes the relationship of the vocal tract length on the perceived brightness or darkness of the speaker's voice. The present study explored the impact of adjustments of the voice focus on oral-nasal balance. The vocal tract settings in question were backward focus (retracted tongue, wide pharynx, and lowered larynx) and forward focus (fronted tongue, constricted pharynx, and raised larynx). The backward focus condition was expected to decrease nasalance scores and the forward focus con... περισσότερα »

World Neurosurgery

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 48 δευτερόλεπτα
- Omental approach to functional recovery after cerebrovascular disease2015-10-20 10:03:36 AM Publication date: Available online 19 October 2015 *Source:*World Neurosurgery Author(s): Marek J. Konieczny, Song-Jin Ri, Janniko Georgiadis Διαβάστε περισσότεραΑρχή - Human Brain to Brain Interface: Prelude to Telepathy2015-10-20 10:03:36 AM Publication date: Available online 19 October 2015 *Source:*World Neurosurgery Author(s): Tariq K. Halasa, Lahari Surapaneni, Mithun G. Sattur, Andrew Pines, Rami James N. Aoun, Bernard ... περισσότερα »

Gait & Posture

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 54 δευτερόλεπτα
- Restricting ankle motion via orthotic bracing reduces toe clearance when walking over obstacles2015-10-20 09:58:07 AM Publication date: Available online 19 October 2015 *Source:*Gait & Posture Author(s): Eftychia Evangelopoulou, Martin Twiste, John G. Buckley Background When trans-tibial amputees cross obstacles leading with their prosthesis, foot clearance is achieved using compensatory swing-phase kinematics. Such compensation would suggest able-bodied individuals normally use swing-phase ankle dorsiflexion to attain adequate obstacle cle... περισσότερα »

Stroke ASAP

Alexi ViadisστοHead and Neck Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Rates and Determinants of 5-Year Outcomes After Atrial Fibrillation-Related Stroke: A Population Study [Original Contribution]Background and Purpose—Demographic trends in atrial fibrillation (AF) incidence may yield a substantial rise in the societal burden of AF-related stroke (AF-stroke). Accurate population-wide outcome data are essential to inform health service planning to improve AF-stroke prevention, and provision of rehabilitation, nursing home, and community supports for AF-stroke survivors.Methods—We investigated rates and determinants of 5-year fatality, stroke recurrence...περισσότερα »

Circulation Research

Alexi ViadisστοHead and Neck Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Unique Features of Cortical Bone Stem Cells Associated with Repair of the Injured Heart [Original Research]*Rationale:* Adoptive transfer of multiple stem cell types has only had modest effects on the structure and function of failing human hearts. Despite increasing use of stem cell therapies, consensus on the optimal stem cell type is not adequately defined. The modest cardiac repair and functional improvement in patients with cardiac disease warrants identification of a novel stem cell population that possesses properties that induce a more substantial improvement in heart failur... περισσότερα »

OtoRhinoLaryngology New Articles,October 19th,2015,a

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Radiofrequency-assisted Liposuction *Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα* *for Arm Contouring: Technique under Local Anesthesia by Theodorou, Spero; Chia, Christopher via Plastic and Reconstructive Surgery – Global Open - Most Popular Articles [image: image]Background: Contouring of the arms that does not involve skin excision remains a difficult challenge due to the dependent nature and quality of the skin. Although brachioplasty remains effective, it requires a lengthy incision. Radiofrequency-assisted liposuction (RFA... περισσότερα »

OtoRhinoLaryngology

Alexi ViadisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 1 ώρα
Ossiculoplasty *Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα* *: A historical perspective by Narmaya Thapa via Indian Journal of Otology *Narmaya Thapa* Indian Journal of Otology 2015 21(4):231-232 Ossiculoplasty is defined as the reconstruction of the ossicular chain. Its historical aspect is worth reviewing. The earliest recorded ossiculoplasty was attempted by Matte in 1901 to re-establish a connection between the tympanic membrane and the oval window in the case of missing ossicles. After a long time, Wullstein in 1951 utilize... περισσότερα »

ORL

Alexi ViadisστοHead and Neck Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Vaccinations against glioma CD40/CD40L expression correlates with the survival of patients with glioblastomas and an augmentation in CD40 signaling enhances the efficacy of vaccinations against glioma modelsChonan, M., Saito, R., Shoji, T., Shibahara, I., Kanamori, M., Sonoda, Y., Watanabe, M., Kikuchi, T., Ishii, N., Tominaga, T., 2015-10-16 08:28:34 AM Background The prognosis of glioblastoma (GBM) remains poor; therefore, effective therapeutic strategies need to be developed. CD40 is a costimulatory molecule whose agonistic antibody has been shown to activate antitumor effects.... περισσότερα »

HeadNeck

Alexi ViadisστοHead and Neck Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging. Clin Imaging. 2015 Authors: Payabvash S, Meric K, Cayci Z Abstract PURPOSE: To differentiate malignant from benign cervical lymph nodes in patients with head/neck cancer. METHODS: In this retrospective study, 39 patients with primary head/neck cancer who underwent Positron Emission Tomography (PET)/Computerized Tomography (CT) and image-guided lymph node biopsy were included. RESULTS: Overall, 23 (59%) patients had biopsy-proven malignant cervical lymphadenop... περισσότερα »

MedJournals

Alexi ViadisστοHead and Neck Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Medical Research Creating healthy heart environment *Neeraj Parakh, G Karthikeyan, Balram Bhargava* The Indian Journal of Medical Research 2015 142(3):235-237The role of vitamin D in polycystic ovary syndrome *Ming-Wei Lin, Meng-Hsing Wu* The Indian Journal of Medical Research 2015 142(3):238-240Knowledge of serotype prevalence & burden of invasive pneumococcal disease: A prerequisite to vaccine introduction in the country *Reba Kanungo* The Indian Journal of Medical Research 2015 142(3):241-244Role of oxidative stress & transient receptor potential in chronic obstructive pulmonar... περισσότερα »

OtoLaryngology New Articles

Alexi ViadisστοHead and Neck Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
The role of cullin proteins in gastric cancer AbstractThe cullin proteins are a family of scaffolding proteins that associate with RING proteins and ubiquitin E3 ligases and mediate substrate–receptor bindings. Thus, cullin proteins regulate the specificity of ubiquitin targeting in the regulation of proteins involved in various cellular processes, including proliferation, differentiation, and apoptosis. There are seven cullin proteins that have been identified in eukaryotes: CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, and CUL7/p53-associated parkin-like cytoplasmic protein. All of thes... περισσότερα »

ENT-ORL

Neuro-Oncology Neuro-Oncology - Advance Access - TNF-{alpha} enhancement of CD62E mediates adhesion of non-small cell lung cancer cells to brain endothelium via CD15 in lung-brain metastasisJassam, S. A., Maherally, Z., Smith, J. R., Ashkan, K., Roncaroli, F., Fillmore, H. L., Pilkington, G. J., 2015-10-16 08:28:36 AM Background CD15, which is overexpressed on various cancers, has been reported as a cell adhesion molecule that plays a key role in non-CNS metastasis. However, the role of CD15 in brain metastasis is largely unexplored. This study provides ... περισσότερα »

Arteriosclerosis, Thrombosis, and Vascular Biology current issue

Alexi ViadisστοHead and Neck Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Neoatherosclerosis From a Pathologist's Point of View [Recent Highlights of ATVB]Correction [Corrections]Correction [Corrections]Gallstone Disease and Increased Risk of Ischemic Heart Disease: Causal Association or Epiphenomenon? [Editorials]Hypertriglyceridemia Associated With Abdominal Obesity: Getting Contributing Factors Into Perspective [Editorials]From Locus Association to Mechanism of Gene Causality: The Devil Is in the Details [Editorials]Inhibited and Uninhibited Platelet Deposition Within a Thrombus: Does It Depend on the Antiplatelet Drug? [Editorials]Modulation of the Co... περισσότερα »

Arteriosclerosis, Thrombosis, and Vascular Biology

Alexi ViadisστοHead and Neck Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Platelet-Associated Matrix Metalloproteinases Regulate Thrombus Formation and Exert Local Collagenolytic Activity [Original Research]Objective—Platelets are increasingly implicated in processes beyond hemostasis and thrombosis, such as vascular remodeling. Members of the matrix metalloproteinase (MMP) family not only remodel the extracellular matrix but also modulate platelet function. Here, we made a systematic comparison of the roles of MMP family members in acute thrombus formation under flow conditions and assessed platelet-dependent collagenolytic activity over time.Approach and...περισσότερα »

Risk Factors for Venous Thromboembolism

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
http://www.venousdisease.com/Publications/Update%20on%20risk%20factors-caprini.pdf Risk Factors Observed in 1231 Consecutive Patients Treated for Acute DVT and/or PE Risk FactorPatients (%)*Age ≥40 years**88.5**Obesity**37.8**History of venous thromboembolism**26.0**Cancer**22.3**Bed rest ≥5 days**12.0**Major surgery**11.2**Congestive heart failure**8.2**Varicose veins**5.8**Fracture (hip or leg)**3.7**Estrogen treatment**2.0**Stroke**1.8**Multiple trauma* *1.1**Childbirth**1.1**Myocardial infarction**0.7*1 or more risks96.32 or more risks76.03 or more risks39.0 Risk Factors for Venou... περισσότερα »

Practical Approaches to Immunotherapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
in the Clinic via Seminars in Oncology Publication date: Available online 19 October 2015 *Source:*Seminars in Oncology Author(s): Sanjiv S. Agarwala The development of immunotherapy using checkpoint blockade has altered the treatment landscape for patients who had but few options only several years back. Currently, approved anti-checkpoint agents include ipilimumab, the first approved treatment aimed against the cytotoxic T-lymphocyte antigen-4 (CTLA-4) pathway, and pembrolizumab and nivolumab, which inhibit the programmed death-1 (PD-1) pathway. Careful monitoring and early interve...περισσότερα »

Papillary thyroid carcinoma (PTC) and Hashimoto’s thyroiditis (HT)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Hashimoto’s Thyroiditis Does Not Affect Ultrasonographical, Cytological, and Histopathological Features in Patients with Papillary Thyroid Carcinoma via Latest Results for Endocrine Pathology AbstractThe association between papillary thyroid carcinoma (PTC) and Hashimoto’s thyroiditis (HT) is controversial. In this study, we aimed to compare preoperative thyroid functions, ultrasonography (US) features, fine-needle aspiration biopsy (FNAB) results, and histopathological characteristics of PTC in patients with and without HT. Data of 919 PTC patients were reviewed retrospectively. The ... περισσότερα »

Transcription Factors in the Accurate Diagnosis of Clinically Nonfunctioning Pituitary Adenomas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
The Complementary Role of via Latest Results for Endocrine Pathology AbstractClinically nonfunctioning pituitary adenomas (NFAs) may be hormonally inactive tumors of differentiated cells, mainly not only gonadotroph adenomas (GAs) but also silent corticotroph adenomas (SCAs) and other differentiated silent adenomas. Recently, the use of transcription factors has been recommended to confirm cytodiffererentiation of these neoplasms. Our objective was to assess the clinical significance of the new classification system using transcription factors. Five hundred sixteen consecutive NFAs ...περισσότερα »

Swallowing Disorders in Sjögren’s Syndrome

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
: Prevalence, Risk Factors, and Effects on Quality of Life via Dysphagia AbstractThis epidemiological investigation examined the prevalence, risk factors, and quality-of-life effects of swallowing disorders in Sjögren’s syndrome (SS). One hundred and one individuals with primary or secondary SS (94 females, 7 males; mean age 59.4, SD = 14.1) were interviewed regarding the presence, nature, and impact of swallowing disorders and symptoms. Associations among swallowing disorders and symptoms, select medical and social history factors, SS disease severity, and the M.D. Anderson Dysphagi... περισσότερα »

Clinical and Translational Allergy is one of several journals in the portfolio of the European Academy of Allergy and Clinical Immunology.

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 1 ώρα
Human in vitro induced T regulatory cells and memory T cells share common demethylation of specific FOXP3 promoter region Background: The FOXP3 gene is the master regulator for T regulatory cells and is under tight DNA methylation control at the Treg specific demethylated region (TSDR) in its first intron. This said, methylation of its promoter region, the significance of which is unknown, has also been associated with various immune-related disease states such as asthma, food allergy, auto-immunity and cancer. Here, we used induced T regulatory cells (iTreg) as a target cell popula...περισσότερα »

Endocrine Pathology

Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
- A Novel Somatic Deletion Mutation of ATP2B3 in Aldosterone-Producing Adenoma2015-10-19 02:00:00 AM Abstract Aldosterone-producing adenoma (APA) is a form of primary aldosteronism (PA). Recent studies suggested that somatic mutations in the *KCNJ5*, *ATP1A1*, *ATP2B3*, and *CACNA1D* genes are involved in the pathogenesis of APA. We report a case of a 62-year-old man diagnosed as PA with left adrenal mass. He underwent adrenalectomy for treatment. We identified a novel somatic deletion mutation in *ATP2B3* in the adrenal tumor: c.1269_1274delTGTGCT whi... περισσότερα »

Developmental delay, seizures, ataxia, altered tone, severely impaired speech and intellect, as well as an overall happy demeanor,frequent bouts of laughter,and hypermotoric behavior

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Angelman Syndrome: A Review Highlighting Musculoskeletal and Anatomical Aberrations by Rohit Sachdeva, Sarah J. Donkers, Soo Y. Kim via Clinical Anatomy ABSTRACT Angelman's syndrome (AS) is a genetic neurodevelopment disorder. The cause is a known abnormality involving the maternal inherited ubiquitin-protein ligase (UBE3A) gene. Clinical characteristics universal to the disorder are well documented in the literature and include developmental delay, seizures, ataxia, altered tone, severely impaired speech and intellect, as well as an overall happy demeanor, frequent bouts of laughter,... περισσότερα »

A 10-year-old female presented with a short history of nasal obstruction, epistaxis, nasal discharge and headache

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
International Journal of Pediatric Otorhinolaryngology Volume 61, Issue 2, 1 ,Pages 161–165 Case report Inflammatory myofibroblastic tumor of the nasal cavity: a case report and review of the literature V Soysala, O.G Yigitbasib, , , O Kontasc, H.A Kahyad, E Guneyb a ENT Clinic of Amasya State Hospital, Turkey b Otorhinolaryngology and Head and Neck Surgery Department of Faculty of Medicine, Erciyes University, Kayseri, Turkey c Pathology Department of Faculty of Medicine, Erciyes University, Kayseri, Turkey d Pathology Department of Amasya State Hospital, Turkey doi:10.1016/S0165-5... περισσότερα »

Sleep Medicine

Alexandros G. SfakianakisστοΥπνική Άπνοια και Διαταραχές ΎπνουΠριν από 2 ώρες
- Benefits and risk of sodium oxybate in idiopathic hypersomnia versus narcolepsy type 1: a chart reviewSmaranda Leu-Semenescu, Pauline Louis, Isabelle Arnulf, 2015-10-20 08:02:55 AM • Sodium oxybate is indicated to treat narcolepsy but not idiopathic hypersomnia• 46 patients with idiopathic hypersomnia were treated with low doses of sodium oxybate• The drug improved daytime sleepiness to the same degree as in patients with narcolepsy type 1• The drug improved severe sleep inertia in 71% of the hypersomnia patients• Side effects (mostly nausea and dizziness) were reporte... περισσότερα »

Inflammatory Myofibroblastic Tumor of the Nasal Cavity and Paranasal Sinuses

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
Inflammatory myofibroblastic tumour of paranasal sinuses with fatal outcome: reactive lesion or tumour? J Clin Pathol. N Gale,1 N Zidar,1 J Podboj,2 M Volavšek,1 and B Luzar1 1Institute of Pathology, Medical Faculty, University of Ljubljana, Korytkova 2, 1000 Ljubljana, Slovenia 2Department of Otorhinolaryngology and Cervicofacial Surgery, Clinical Centre, Zaloška 2, 1000 Ljubljana, Slovenia Correspondence to: Professor N Gale, Institute of Pathology, Medical Faculty, University of Ljubljana, Korytkova 2, 1000 Ljubljana, Slovenia; is.jl-inu.fm@elag.anin Abstract Inflammatory myofibrobl... περισσότερα »

A virtual-reality simulator for myringotomy with tube placement

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
Face and content validity of by Caiwen Huang via Journal of Otolaryngology - Head & Neck Surgery Background: Myringotomy with tube insertion can be challenging for junior Otolaryngology residents as it is one of the first microscopic procedures they encounter. The Western myringotomy simulator was developed to allow trainees to practice microscope positioning, myringotomy, and tube placement. This virtual-reality simulator is viewed in stereoscopic 3D, and a haptic device is used to manipulate the digital ear model and surgical tools.ObjectiveTo assess the face and content validity o...περισσότερα »

Guideline-adherent treatment in cluster headache is about 70% for acute treatment and about 35% for prophylactic treatment

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
Evaluation of guideline-adherent treatment in cluster headache by Lademann, V., Jansen, J.-P., Evers, S., Frese, A. via Cephalalgia -- Preview Articles BackgroundSeveral treatment guidelines exist for cluster headache. However, it is not yet known how many cluster headache patients are treated according to these guidelines. MethodsWe enrolled 434 cluster headache patients with confirmed diagnosis referred to two tertiary pain centers. The history of treatment was registered and analyzed according to the treatment guidelines of the European Federation of Neurological Societies. Results...περισσότερα »

A clinical diagnosis of classical trigeminal neuralgia (CTN)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
(part I): Revisiting the clinical phenotype by Haviv, Y., Khan, J., Zini, A., Almoznino, G., Sharav, Y., Benoliel, R. via Cephalalgia -- Preview Articles AimsWe conducted a cross-sectional study to re-examine the clinical profile of patients with a clinical diagnosis of classical trigeminal neuralgia (CTN). MethodsInclusion criteria consisted of the International Headache Society’s published classification of CTN. For the specific purposes of the study, features such as autonomic signs, persistent background pain, attack durations of >2 minutes and reports of pain-related awakening w... περισσότερα »

Cochlear implant programming decreases impedance and improves tinnitus symptoms

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
Suppression of Tinnitus in Chinese Patients Receiving Regular Cochlear Implant Programming by Liu, Y., Wang, H., Han, D. X., Li, M. H., Wang, Y., Xiao, Y. L. via Annals of Otology, Rhinology & Laryngology RSS feed -- OnlineFirst Articles Objective:To assess the clinical effect of cochlear implant programming on tinnitus. Methods:Tinnitus patients (n = 234) were divided into 3 groups: (1) preoperative tinnitus (n = 108), (2) postoperative tinnitus occurring before implant switch-on at week 4 (n = 88), and (3) tinnitus occurring more than 1 year postoperatively (n = 44). Patients in eac... περισσότερα »

Glottic Carcinoma in Situ and Stage I Cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
Treatment and Survival Trends in Glottic Carcinoma in Situ and Stage I Cancer From 1988 to 2012 by Khaja, S. F., Hoffman, H. T., Pagedar, N. A. via Annals of Otology, Rhinology & Laryngology RSS feed -- OnlineFirst Articles Objective:To identify trends in treatment and survival for patients with stage I glottic cancer and glottic carcinoma in situ (CIS). Methods:The 18-registry SEER data were analyzed for CIS and stage I glottic cancer. Treatment variables and observed and relative survival were assessed separately for stage I and glottic CIS. Results:Among 14 025 cases of stage I glot...περισσότερα »

Increased risk of heart failure in women with symptoms of sleep disordered breathing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
Increased risk of heart failure in women with symptoms of sleep disordered breathing by Mirjam Ljunggren, Liisa Byberg, Jenny Theorell-Haglöw, Bertil Lindahl, Karl Michaëlsson, Eva Lindberg via Sleep Medicine Highlights • Population based cohort study where 5,998 women were followed for 11 years • Information on heart failure incidence was obtained from national registries • Women with symptoms of SDB had an increased risk of developing heart failure AbstractBackground An association between obstructive sleep apnea and the incidence of heart failure has been reported in men but not in ...περισσότερα »

Autonomic dysfunction in primary sleep disorders

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
Autonomic dysfunction in primary sleep disorders [image: Abstract Image] by Mitchell G. Miglis via Sleep Medicine Highlights • Cell populations that help regulate the sleep and waking state are closely situated to cell populations that help regulate autonomic function. • Non-REM sleep is a state of relative autonomic stability and metabolic recovery, while REM sleep is a state of autonomic instability. • Obstructive sleep apnea can result in a major stress on the autonomic nervous system and lead to significant morbidity and mortality. • Sleep deprivation alone can increase sympathetic d... περισσότερα »

Diagnostic Cytopathology

Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 2 ώρες
- Use of fine-needle aspirate calcitonin to detect medullary thyroid carcinoma: A systematic reviewPierpaolo Trimboli, Leo Guidobaldi, Massimo Bongiovanni, Anna Crescenzi, Maria Alevizaki, Luca Giovanella, 2015-10-20 08:17:50 AM Background The measurement of calcitonin in washout fluids of thyroid nodule aspirate (FNA-calcitonin) has been reported as accurate to detect medullary thyroid carcinoma (MTC). The results from these studies have been promising and the most updated version of ATA guidelines quoted for the first time that “*FNA findings that ar... περισσότερα »

A strong role for TROP-2 in separating PTC from BTN

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
TROP-2 expression in papillary thyroid carcinoma by Anthony Simms, Reuben P. Jacob, Cynthia Cohen, Momin T. Siddiqui via Diagnostic Cytopathology TROP-2 is a type I transmembrane glycoprotein which is over-expressed in various malignancies, and is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. In this study, we evaluated TROP-2 expression in papillary thyroid carcinoma (PTC) and compared it to other thyroid neoplastic and non-neoplastic lesions. Immunohistochemical (IHC) evaluation for TROP-2 was performed on 137 thyroid fine needle aspiratio... περισσότερα »

Journal of Plastic, Reconstructive & Aesthetic Surgery

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 2 ώρες
- Aesthetic and oncologic outcomes after one-stage immediate breast reconstruction using a permanent biodimensional expandable implantA. Agusti, A. Ward, C. Montgomery, K. Mohammed, G.P.H. Gui, 2015-10-20 07:56:56 AM Immediate breast reconstruction (IBR) with implants is the commonest method of reconstructive surgery after mastectomy. With careful patient selection, a stable implant pocket can be created at the primary operation to decrease the likelihood of further surgery to adjust the reconstructed side. One-stage IBR is cost effective but failed procedures requir... περισσότερα »

Use of fine-needle aspirate calcitonin to detect medullary thyroid carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
: A systematic review by Pierpaolo Trimboli, Leo Guidobaldi, Massimo Bongiovanni, Anna Crescenzi, Maria Alevizaki, Luca Giovanella viaDiagnostic Cytopathology Background The measurement of calcitonin in washout fluids of thyroid nodule aspirate (FNA-calcitonin) has been reported as accurate to detect medullary thyroid carcinoma (MTC). The results from these studies have been promising and the most updated version of ATA guidelines quoted for the first time that “*FNA findings that are inconclusive or suggestive of MTC should have calcitonin measured in the FNA washout fluid*.” Here we...περισσότερα »

Autonomic dysfunction in primary sleep disorders

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
Article in Press Highlights • Cell populations that help regulate the sleep and waking state are closely situated to cell populations that help regulate autonomic function. • Non-REM sleep is a state of relative autonomic stability and metabolic recovery, while REM sleep is a state of autonomic instability. • Obstructive sleep apnea can result in a major stress on the autonomic nervous system and lead to significant morbidity and mortality. • Sleep deprivation alone can increase sympathetic drive. • Autonomic complaints are common in patients with restless leg syndrome. • There is a clos... περισσότερα »

Primary snoring in children - the effect of adenotonsillectomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
*Article in Press* The history of *Adi Borovich, MD, Yakov Sivan, MD, Michal Greenfeld, MD, Riva Tauman, MD[image: correspondence][image: email]* *DOI: http://dx.doi.org/10.1016/j.sleep.2015.10.002* *- * Abstract *Primary snoring (PS) is considered the most benign form of sleep disordered breathing (SDB), and treatment is usually not prescribed. Studies suggest that PS may not be as benign as had formerly been considered. We aimed to investigate the natural history of PS in children with adenotonsillar hypertrophy and compare those who underwent adenotonsillectomy with those wh...περισσότερα »

Journal of Plastic, Reconstructive & Aesthetic Surgery

Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 2 ώρες
- Aesthetic and oncologic outcomes after one-stage immediate breast reconstruction using a permanent biodimensional expandable implantA. Agusti, A. Ward, C. Montgomery, K. Mohammed, G.P.H. Gui, 2015-10-20 07:56:56 AM Immediate breast reconstruction (IBR) with implants is the commonest method of reconstructive surgery after mastectomy. With careful patient selection, a stable implant pocket can be created at the primary operation to decrease the likelihood of further surgery to adjust the reconstructed side. One-stage IBR is cost effective but failed procedures requir... περισσότερα »

Antineutrophil Cytoplasmic Antibody–Positive Small-Vessel Vasculitis Associated with Antithyroid Drug Therapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 2 ώρες
: How Significant Is the Clinical Problem? by Anne-Sophie Balavoine via liebertpub1 Thyroid , Vol. 0, No. 0. Author information Anne-Sophie Balavoine,1,* Daniel Glinoer,2 Sylvain Dubucquoi,3 and Jean-Louis Wémeau1,3 1Service of Endocrinology and Metabolic Diseases, CHRU de Lille, Lille, France. 2Department of Internal Medicine, Division of Endocrinology, University Hospital Saint Pierre, Brussels, Belgium. 3Institut d'Immunologie, CHRU de Lille, Lille, France. *Present Address: Service of Endocrinology, Tourcoing Hospital, Tourcoing, France. Address correspondence to: *Anne-Sophie Bala... περισσότερα »

The oral histone deacetylase inhibitor abexinostat in relapsed/refractory lymphoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
A phase I/II multicenter, open-label study of by Evens, A. M., Balasubramanian, S., Vose, J. M., Harb, W., Gordon, L. I., Langdon, R., Sprague, J., Sirisawad, M., Mani, C., Yue, J., Luan, Y., Horton, S., Graef, T., Bartlett, N. L. via Clinical Cancer Research Online First Articles Purpose: Additional targeted therapies are needed for the treatment of lymphoma. Abexinostat is an oral pan-histone deacetylase inhibitor (HDACi) displaying potent activity in preclinical models. We conducted a multicenter phase I/II study (N=55) with single-agent abexinostat in relapsed/refractory lymphom...περισσότερα »

Ultrasound Guided Intercostobrachial Peri-Neural Injection for Intercostobrachial Neuralgia

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 ώρες
in Breast Cancer Patients: A Case Series by Eric M. Wisotzky, Vikramjeet Saini, Cyrus Kao via The American Academy of Physical Medicine and Rehabilitation (AAPM&R) This case series describes three cases in which ultrasound-guided intercostobrachial peri-neural injection was used for intercostobrachial neuralgia, a common cause of postmastectomy pain syndrome. All cases had undergone modified radical mastectomy with axillary lymph node dissection for breast cancer. Two cases developed axillary and unilateral chest wall pain. The third case initially presented with axillary pain and la...περισσότερα »

The American Academy of Physical Medicine and Rehabilitation (AAPM&R)

Alexandros G. SfakianakisστοEvolutionary physiologyΠριν από 3 ώρες
- Acute Responses of FES-Cycling on VE/VCO Ratio and Substrate Utilization after Spinal Cord InjuryAshraf S. Gorgey, Justin Lawrence, 2015-10-20 07:19:53 AM Ventilation to carbon dioxide ratio is comparable to peak oxygen uptake in the prognosis of cardiovascular disorders. Currently, there are no established indices to determine the submaximal effects of functional electrical stimulation on cardiovascular performance in persons with spinal cord injury. Read moreTop - Translation of a Motor Learning Walking Rehabilitation Program into a Group-based Exercise Pro... περισσότερα »

Microbiology

Alexandros G. SfakianakisστοΛοίμωξηΠριν από 12 ώρες
[image: feedamail.com] Microbiology via ola Kala on Inoreader (Sponsor this newsletter) A novel DNA-binding protein from Campylobacter jejuni bacteriophage NCTC12673 We previously suggested that the double-stranded genomic DNA of *Campylobacter jejuni* bacteriophage NCTC12673 was complexed with proteins. Mass spectrometry of peptides obtained from tryptic digests of purified phage DNA indicated that phage protein Gp001 co-purified with the DNA. Gp001 is an acidic protein that lacks any obvious homology or conserved domains found in known DNA-binding proteins. The DNA-binding ab... περισσότερα »

Toxic epidermal necrolysis associated with radiotherapy and phenytoin

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 ώρες
in a patient with non-Hodking's lymphoma: A case report via ScienceDirect Publication: Reports of Practical Oncology & Radiotherapy Publication date: Available online 17 October 2015 *Source:*Reports of Practical Oncology & Radiotherapy Author(s): Fatma Keklik, Melda Cömert Özkan, Gizem Kocabaş Yenipazar, Banu Yaman, Güray Saydam, Fahri Şahin Toxic epidermal necrolysis (TEN) is a disease which is characterized by fever and desquamation of the skin and mucosal membranes. It is usually related with drugs, especially aromatic anticonvulsants which are recognized as the most common cause o... περισσότερα »

Current Treatment Options in Allergy

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 19 ώρες
- Review of Contact Urticaria Syndrome—Evaluation to Treatment2015-10-17 02:00:00 AM Read moreTop - Another Great Imitator: Allergic Contact Dermatitis Differential Diagnosis, Clues to Diagnosis, Histopathology, and Treatment2015-10-16 02:00:00 AM Opinion statement Allergic contact dermatitis (ACD) is a type IV (delayed) hypersensitivity reaction that has a wide spectrum of presentations that often imitate or overlap with other cutaneous eruptions. Differential diagnoses to consider include infections, skin lymphoma-malignancies, inflammatory der... περισσότερα »

Dysphagia

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 19 ώρες
- Letter to the Editor2015-10-01 02:00:00 AM Read moreTop - Videoendoscopic Evaluation of Swallowing After Thyroidectomy: 7 and 60 Days2015-10-01 02:00:00 AM Abstract Deglutition complaints are frequent after thyroidectomy. The purpose of this study was to follow-up on patients with thyroidectomy indication to compare the videoendoscopic evaluation of swallowing on the seventh day (early postoperative, EPO) and on the 60th day after thyroidectomy, (late postoperative, LPO) and to compare patients that evolved with normal laryngeal mobility (NLM) and ... περισσότερα »

Academic Emergency Medicine

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 19 ώρες
- Comparison of Two Sepsis Recognition Methods in a Pediatric Emergency DepartmentFran Balamuth, Elizabeth R. Alpern, Robert W. Grundmeier, Marianne Chilutti, Scott L. Weiss, Julie C. Fitzgerald, Katie Hayes, Warren Bilker, Ebbing Lautenbach, 2015-10-19 15:18:24 PM Abstract Objectives The objective was to compare the effectiveness of physician judgment and an electronic algorithmic alert to identify pediatric patients with severe sepsis/septic shock in a pediatric emergency department (ED). Methods This was an observational cohort study of patients ol... περισσότερα »

Revista de Logopedia, Foniatría y Audiología

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 19 ώρες
- Documento de consenso elaborado por el comité de expertos en TEL sobre el diagnóstico del trastorno2015-10-19 15:16:56 PM Publication date: Available online 1 October 2015 *Source:*Revista de Logopedia, Foniatría y Audiología Author(s): G. Aguado, C.J. Coloma, A.B. Martínez, E. Mendoza, A. Montes, R. Navarro, M. Serra Read moreTop - Study of the Specific Language Impairment in a three-generation family2015-10-19 15:16:56 PM Publication date: Available online 26 September 2015 *Source:*Revista de Logopedia, Foniatría y Audio... περισσότερα »

International Surgery

Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 19 ώρες
- The basic molecular biology of angiogenesis and its implication in anticancer therapeuticsSujan Narayan Agrawal, 2015-10-19 00:00:00 AM *Sujan Narayan Agrawal* Archives of International Surgery 2015 5(3):121-130 Angiogenesis is a physiological process through which new blood vessels are formed from the existing blood vessels. It is a multistep process, involving proliferation of activated endothelial cells (ECs) and migration of ECs to target organs. At target organs, the ECs get organized into capillary tubes and synthesize new basement membrane.... περισσότερα »

Dental and Allied Sciences

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρικήΠριν από 19 ώρες
Journal of Dental and Allied Sciences : 2015 - 4(1)SubscribeOpen Feed Reader Subscribe to: Feedly - Archie Cochrane: The Pioneer of Fourth Revolution of Health CareJayant N Palaskar, 2015-10-19 00:00:00 AM *Jayant N Palaskar* Journal of Dental and Allied Sciences 2015 4(1):1-2 Read moreTop - Extraction: A Parameter in Bolton RatioPriyanka Vilas Kale, 2015-10-19 00:00:00 AM *Priyanka Vilas Kale, Dhiraj Rajendra Chhajed, Shivani Shailendra Khapli, Nitin Rameshchandra Tripathi, Gurjeet Kaur Gurmeet Singh Randhawa* Journal of Dental and Allied Sciences ... περισσότερα »

Nutrition, Pharmacology, Neurological Diseases

Alexandros G. SfakianakisστοΘεραπείαΠριν από 19 ώρες
- A research milieu calls for attention: Biological clock in health and diseasePerumal Subramanian, 2015-10-19 00:00:00 AM *Perumal Subramanian* International Journal of Nutrition, Pharmacology, Neurological Diseases 2015 5(4):117-117 Read moreTop - Recent advances in pharmacological management of substance use disordersDiwakar Sharma, 2015-10-19 00:00:00 AM *Diwakar Sharma, Sujita Kumar Kar* International Journal of Nutrition, Pharmacology, Neurological Diseases 2015 5(4):118-127 Pharmacological management is an important pillar in the ... περισσότερα »

American Journal of Audiology

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 19 ώρες
Current Issue - Internet and Audiology: A Review of the First International MeetingAndersson G, Lunner T, Laplante-Lévesque A, et al. , 2015-09-01 03:00:00 AM Purpose The purpose of this research forum article is to describe the impetus for holding the First International Meeting on Internet and Audiology (October 2014) and to introduce the special research forum that arose from the meeting. Method The rationale for the First International Meeting on Internet and Audiology is described. This is followed by a short description of the research sections... περισσότερα »

OtoRhinoLaryngology New Articles,October 19th,2015,a

Alexandros G. SfakianakisστοMedicine by Alexandros G. SfakianakisΠριν από 19 ώρες
Radiofrequency-assisted Liposuction *Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα* *for Arm Contouring: Technique under Local Anesthesia by Theodorou, Spero; Chia, Christopher via Plastic and Reconstructive Surgery – Global Open - Most Popular Articles [image: image]Background: Contouring of the arms that does not involve skin excision remains a difficult challenge due to the dependent nature and quality of the skin. Although brachioplasty remains effective, it requires a lengthy incision. Radiofrequency-assisted liposuction (RFAL... περισσότερα »

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