Head and Neck Diseases by Alexandros G.Sfakianakis: OtoRhinoLaryngology & Medicine,New Articles,June 23rd,2016,afternoon

Πέμπτη 23 Ιουνίου 2016

OtoRhinoLaryngology & Medicine,New Articles,June 23rd,2016,afternoon

Brain correlates of the orientation of auditory spatial attention onto speaker location in a "cocktail-party" situation

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 31 δευτερόλεπτα

Abstract Successful speech perception in complex auditory scenes with multiple competing speakers requires spatial segregation of auditory streams into perceptually distinct and coherent auditory objects and focusing of attention toward the speaker of interest. Here, we focused on the neural basis of this remarkable capacity of the human auditory system and investigated the spatiotemporal sequence of neural activity within the cortical network engaged in solving the "cocktail-party" problem. Twenty-eight subjects localized a target word in the presence of three competing sound sour... περισσότερα »

Per protocol analysis of therapeutic efficacy of chloroquine for the treatment of Plasmodium vivax malaria in children

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 3 δευτερόλεπτα

2016-06-23T06-02-08Z *Source:* International Journal of Contemporary Pediatrics Leeha Singh, Surbhi Rathi, Santosh Kondekar, Alpana Kondekar, Swapnaja Dongare. Background: High incidence of chloroquine-resistant vivax malaria has led to increasing case fatality and incidence of complicated malaria with Plasmodium vivax contributing to morbidity and mortality. Current guidelines recommend the use of chloroquine along with tissue schizontcides like primaquine for the treatment of Plasmodium vivax malaria. There were reports of increasing resistance to chloroquine in Plasmodium vivax spe... περισσότερα »

A 5-year retrospective analysis of patients with primary vesicoureteral reflux undergoing open surgery; an assessment of 60 patients

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 3 δευτερόλεπτα

2016-06-23T05-59-45Z *Source:* Medicine Science | International Medical Journal Mehmet Nuri Cevizci, Soner Sertan Kara, Alev Cansu Ayan, Abdlkadir Kaya, Hediye Cevizci. Vesicoureteral reflux (VUR) describes the backward flow of urine from the bladder to the ureter and/or kidney. In this study, 60 patients below 18 years of age diagnosed with primary VUR in our clinic between 2010 and 2014 and undergoingureteroneocystotomy using various open surgery techniques were evaluated retrospectively. Diagnosis of VUR was based on voiding cystourethrography (VCUG). Urinary system ultrasonography... περισσότερα »

Pseudopregnancy in a Doe and Its Hormonal Therapy

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 3 δευτερόλεπτα

2016-06-23T05-44-48Z *Source:* International Journal of Livestock Research NURUL FARLIANA MD, NURHUSIEN YIMER. A female Saanen goat, weighing about 65kg with a body condition score of 3 out of 5, and a history of distended abdomen and udder enlargement for a prolonged period with no subsequent kidding was visited for pregnancy check up. Physical examination of the abdomen revealed abdominal distention with presence of fluid felt up on ballottement as well as udder enlargement. Subsequent examination by abdominal ultrasonography confirmed presence of massive clear anechoic uterine flui... περισσότερα »

Cadmium-Induced Testicular Toxicity, Oxidative Stress and Histopathology in Wistar Rats: Sustained Effects of Polyphenol-Rich Extract of Vernonia Amygdalina (Del.) Leaf

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 3 δευτερόλεπτα

2016-06-23T03-46-30Z *Source:* Journal of Interdisciplinary Histopathology Christian Eseigbe Imafidon, Olatoye Taiwo Risikat, Bamidele Funminiyi Samuel, Ojo Opeyemi Esther, Ademoye Kehinde Aderonke. Background: Cadmium (Cd) is a toxic heavy metal of both environmental and occupational concerns. The health impact of ethno-botanical approaches in attempts to ameliorate its deleterious effects in biological systems should be an area of scientific interest since established therapies are often burdened with undesirable side effects. Aim: To determine the effects of polyphenol-rich extract... περισσότερα »

Sleep Stage Coordination of Respiration and Swallowing: A Preliminary Study

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

Abstract Swallowing is an important physiological response that protects the airway. Although aspiration during sleep may cause aspiration pneumonia, the mechanisms responsible have not yet been elucidated. We evaluated the coordination between respiration and swallowing by infusing water into the pharynx of healthy young adults during each sleep stage. Seven normal subjects participated in the study. During polysomnography recordings, to elicit a swallow we injected distilled water into the pharynx during the awake state and each sleep stage through a nasal catheter. We assessed s... περισσότερα »

Development of a Multimedia Dysphagia Assessment Learning System Using Responsive Web Design: From e-Learning to m-Learning.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

*Development of a Multimedia Dysphagia Assessment Learning System Using Responsive Web Design: From e-Learning to m-Learning.* Stud Health Technol Inform. 2016;225:619-620 Authors: Huang HC, Guo SH Abstract Swallowing problems have significant affect the health outcome of some residents in long-term care facilities. Nursing staff who care these residents should have the ability of assessing dysphagia. However, nursing continued education to improve the performance of dysphagia assessment is still challenged. To enhance nurses' capability of dysphagia assessment, a Multimedia Dysp... περισσότερα »

Achalasia: From Bench to Peroral Endoscopic Myotomy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

*Achalasia: From Bench to Peroral Endoscopic Myotomy.* Dig Dis. 2016 Jun 22;34(5):476-482 Authors: Boeckxstaens GE Abstract Achalasia is a primary esophageal motility disorder with an estimated annual incidence of 1 per 100,000 persons. It is characterized by the absence of esophageal peristalsis and failure of the lower esophageal sphincter (LES) to relax upon swallowing, resulting in progressively severe dysphagia for solids and liquids, regurgitation, aspiration, chest pain and weight loss. Achalasia results from a loss of enteric neurons, most likely due to an autoimmune reac... περισσότερα »

Nonthyroid Metastasis to the Thyroid Gland: Case Series and Review with Observations by Primary Pathology.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

*Nonthyroid Metastasis to the Thyroid Gland: Case Series and Review with Observations by Primary Pathology.* Otolaryngol Head Neck Surg. 2016 Jun 21; Authors: Russell JO, Yan K, Burkey B, Scharpf J Abstract OBJECTIVE: Nonthyroid metastases to the thyroid gland can cause morbidity, including dysphagia, dysphonia, and airway compromise. Because metastatic malignancies portend a poor prognosis, obtaining equipoise between treatment morbidity and local disease progression is paramount. We reviewed cases of nonthyroid metastases to determine treatment and prognostic recommendations. S... περισσότερα »

Clinical Reasoning: An 11-year-old boy with language disorder and epilepsy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Clinical Reasoning: An 11-year-old boy with language disorder and epilepsy.* Neurology. 2016 Feb 2;86(5):e48-53 Authors: Dong L, Zhou XQ PMID: 26833943 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1PgEvCh περισσότερα »

Gastroesophageal Reflux Disease and Sleeve Gastrectomy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

[image: http:--production.springer.de-OnlineReso] Related Articles *Gastroesophageal Reflux Disease and Sleeve Gastrectomy.* Obes Surg. 2015 Dec;25(12):2430-5 Authors: Melissas J, Braghetto I, Molina JC, Silecchia G, Iossa A, Iannelli A, Foletto M Abstract Gastroesophageal reflux disease (GERD) and/or hiatus hernia (HH) are one of the most common disorders of the upper gastrointestinal tract. Despite the positive effect of sleeve gastrectomy (SG) regarding weight loss and improvement in obesity co-morbidities, there are concerns about the development of de novo gastroesophageal re... περισσότερα »

Rare presentation of orbital plasmablastic lymphoma with oral cavity involvement in an HIV-negative patient.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Rare presentation of orbital plasmablastic lymphoma with oral cavity involvement in an HIV-negative patient.* BMJ Case Rep. 2015;2015 Authors: Podder S, Khetan P, Sivamurthy S, Mandal K Abstract Plasmablastic lymphoma is described as a subtype of non-Hodgkin's lymphoma under the category of diffuse large B-cell lymphoma. It is classified by WHO as HIV-associated lymphoma of the oral cavity. Several cases have been reported in non-HIV patients with extra-oral involvement. The characteristic immunohistochemical mark... περισσότερα »

A multisensor approach to improve manometric analysis of the upper esophageal sphincter.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *A multisensor approach to improve manometric analysis of the upper esophageal sphincter.* Laryngoscope. 2016 Mar;126(3):657-64 Authors: Jones CA, Ciucci MR, Hammer MJ, McCulloch TM Abstract OBJECTIVES/HYPOTHESIS: High-resolution manometry (HRM) improves on previous manometric systems by including a greater number of sensors that are more densely placed. Due to deglutitive movement of the HRM catheter and upper esophageal sphincter (UES), it is unclear which HRM sensors capture pressure in the UES. To address this ... περισσότερα »

A Novel Sleep Positioning Device Reduces Gastroesophageal Reflux: A Randomized Controlled Trial.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *A Novel Sleep Positioning Device Reduces Gastroesophageal Reflux: A Randomized Controlled Trial.* J Clin Gastroenterol. 2015 Sep;49(8):655-9 Authors: Person E, Rife C, Freeman J, Clark A, Castell DO Abstract GOAL: We hypothesized that sleeping left-side down with the head/torso elevated reduces recumbent gastroesophageal reflux (GER). BACKGROUND: Previous studies show that sleeping with head of bed elevated or on wedge reduces GER and lying left-side down reduces GER versus right-side down and supine. No prior stud... περισσότερα »

Changes in Health-Related Quality of Life After Gastric Bypass in Patients With and Without Obesity-Related Disease.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

[image: http:--production.springer.de-OnlineReso] Related Articles *Changes in Health-Related Quality of Life After Gastric Bypass in Patients With and Without Obesity-Related Disease.* Obes Surg. 2015 Dec;25(12):2408-16 Authors: Risstad H, Søvik TT, Hewitt S, Kristinsson JA, Fagerland MW, Bernklev T, Mala T Abstract BACKGROUND: A substantial proportion of severely obese patients undergoing bariatric surgery have not developed disease as a consequence of obesity. Little is known about the effects of bariatric surgery on health-related quality of life (HRQL) in this patient group. ... περισσότερα »

The Effect of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy Surgery on Dietary Intake, Food Preferences, and Gastrointestinal Symptoms in Post-Surgical Morbidly Obese Lebanese Subjects: A Cross-Sectional Pilot Study.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

[image: http:--production.springer.de-OnlineReso] Related Articles *The Effect of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy Surgery on Dietary Intake, Food Preferences, and Gastrointestinal Symptoms in Post-Surgical Morbidly Obese Lebanese Subjects: A Cross-Sectional Pilot Study.* Obes Surg. 2015 Dec;25(12):2393-9 Authors: El Labban S, Safadi B, Olabi A Abstract BACKGROUND: Data on gastrointestinal (GI) and dietary changes following bariatric surgery are scarce in the Middle Eastern region. The objective of this work was to retrospectively compare dietary intake, food prefer... περισσότερα »

Clinical Reasoning: An 11-year-old boy with language disorder and epilepsy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

Gastroesophageal Reflux Disease and Sleeve Gastrectomy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

Rare presentation of orbital plasmablastic lymphoma with oral cavity involvement in an HIV-negative patient.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

Dysphagia aortica: a rare cause of dysphagia.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 6 δευτερόλεπτα

[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Dysphagia aortica: a rare cause of dysphagia.* BMJ Case Rep. 2015;2015 Authors: Abdul Haziz SR, Bickle I, Chong VH Abstract Dysphagia is uncommon; however, it is considered a warning symptom, especially in the elderly population, and should prompt consideration of a neoplasm of the oesophagus. Dysphagia aortica is rare and often not considered in clinical practice. It is caused by any abnormality of the aorta that results in dysphagia. These include thoracic aortic aneurysm, aortic dissection and even a tortuous a... περισσότερα »

Tongue thickness evaluation using ultrasonography can predict swallowing function in amyotrophic lateral sclerosis patients.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα

[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Tongue thickness evaluation using ultrasonography can predict swallowing function in amyotrophic lateral sclerosis patients.* Clin Neurophysiol. 2016 Feb;127(2):1669-74 Authors: Nakamori M, Hosomi N, Takaki S, Oda M, Hiraoka A, Yoshikawa M, Matsushima H, Ochi K, Tsuga K, Maruyama H, Izumi Y, Matsumoto M Abstract OBJECTIVE: Dysphagia is a critical issue in amyotrophic lateral sclerosis (ALS) patients. An evaluation of swallowing function is important for assessing the risk of aspiration. We investigated the validity... περισσότερα »

Onabotulinum toxin A dosage trends over time for adductor spasmodic dysphonia: A 15-year experience.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα

[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Onabotulinum toxin A dosage trends over time for adductor spasmodic dysphonia: A 15-year experience.* Laryngoscope. 2016 Mar;126(3):678-81 Authors: Tang CG, Novakovic D, Mor N, Blitzer A Abstract OBJECTIVES/HYPOTHESIS: Although onabotulinum neurotoxin A (BoNTA) has been used for over three decades for the treatment of adductor spasmodic dysphonia, no study has been performed to look at the trend of BoNTA dosages across time. The goal of this study is to evaluate the dosage trends to determine if the dosage necessa... περισσότερα »

A multisensor approach to improve manometric analysis of the upper esophageal sphincter.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα

A Novel Sleep Positioning Device Reduces Gastroesophageal Reflux: A Randomized Controlled Trial.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα

Changes in Health-Related Quality of Life After Gastric Bypass in Patients With and Without Obesity-Related Disease.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα

Randomized Trial of Small-diameter Versus Large-diameter Esophageal Stents for Palliation of Malignant Esophageal Obstruction.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα

[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Randomized Trial of Small-diameter Versus Large-diameter Esophageal Stents for Palliation of Malignant Esophageal Obstruction.* J Clin Gastroenterol. 2015 Sep;49(8):660-5 Authors: White RE, Chepkwony R, Mwachiro M, Burgert SL, Enders FT, Topazian M Abstract GOALS: To assess the effect of esophageal stent diameter on outcomes of patients with malignant esophageal obstruction. BACKGROUND: Esophageal self-expandable metal stents (SEMS) effectively palliate dysphagia due to malignancy, but the best stent diameter is u... περισσότερα »

The Effect of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy Surgery on Dietary Intake, Food Preferences, and Gastrointestinal Symptoms in Post-Surgical Morbidly Obese Lebanese Subjects: A Cross-Sectional Pilot Study.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 7 δευτερόλεπτα

Follicular Variant of Papillary Thyroid Carcinoma: Hybrid or Mixture?

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Follicular Variant of Papillary Thyroid Carcinoma: Hybrid or Mixture?: [image: access_free.gif] Thyroid , Vol. 0, No. 0. [image: Free first page] from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/28OWTnx via IFTTT περισσότερα »

Surgeon volume in thyroid surgery: Surgical efficiency, outcomes, and utilization

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Surgeon volume in thyroid surgery: Surgical efficiency, outcomes, and utilization: [image: cover.gif?v=1&s=fdf3bf895114aa3ba0986593] Objectives/Hypothesis To test our hypothesis that high-surgeon volume is associated with improved surgical efficiency and 30-day outcomes, and lower hospital utilization. Study Design Retrospective observational cohort, 2008–2013. Methods A total of 3,135 patients with hemithyroidectomy or total thyroidectomy performed by a high-volume surgeon, propensity score-matched to 3,135 patients with the same procedure performed by a low-volume surgeon. A... περισσότερα »

Perceptual analysis of the male-to-female transgender voice after glottoplasty—the telephone test

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Perceptual analysis of the male-to-female transgender voice after glottoplasty—the telephone test: [image: cover.gif?v=1&s=fdf3bf895114aa3ba0986593] Objectives/Hypothesis The aim of this investigation was to quantify gender perception in telephone communication as a situation of everyday life. Study Design Matched control study. Methods Speech samples were recorded of 18 male to female (MtF) after Wendler's glottoplasty, 18 male, and 18 female persons. After adaption of the frequency to the limited frequency transmission on the telephone (300–3,400 Hz), the speech samples were... περισσότερα »

The microbiome of otitis media with effusion

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

The microbiome of otitis media with effusion: [image: cover.gif?v=1&s=fdf3bf895114aa3ba0986593] Objectives/Hypothesis The adenoid pad has been considered a reservoir for bacteria in the pathogenesis of otitis media with effusion. This study aimed to characterize the middle ear microbiota in children with otitis media with effusion and establish whether a correlation exists between the middle ear and adenoid microbiota. Study Design Prospective, controlled study. Methods Middle ear aspirates adenoid pad swabs were collected from 23 children undergoing ventilation tube insertion... περισσότερα »

Palliative head and neck radiotherapy with the RTOG 8502 regimen for incurable primary or metastatic cancers.

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

[image: http:--linkinghub.elsevier.com-ihub-imag] Authors: Lok BH, Jiang G, Gutiontov S, Lanning RM, Sridhara S, Sherman EJ, Tsai CJ, McBride SM, Riaz N, Lee NY Abstract OBJECTIVES: To report on our institutional experience of palliative radiotherapy (RT) of cancers in the head and neck by the RTOG 8502 'QUAD SHOT' regimen. METHODS: Seventy-five patients completed at least 1 cycle of palliative RT to the head and neck for primary or metastatic disease based on the RTOG 8502 regimen (3.7 Gy twice daily over 2 consecutive days at 4 week intervals per cycle) between 2/2005 and 7/2... περισσότερα »

Towards a HPV Vaccine Knowledgebase

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

for Patient Education Content.: Stud Health Technol Inform. 2016;225:432-436 Authors: Wang D, Cunningham R, Boom J, Amith M, Tao C Abstract Human papillomavirus is a widespread sexually transmitted infection that can be prevented with vaccination. However, HPV vaccination rates in the United States are disappointingly low. This paper will introduce a patient oriented web ontology intended to provide an interactive way to educate patients about HPV and the HPV vaccine that will to empower patients to make the right vaccination decision. The information gathered for this initial dr... περισσότερα »

Human papillomavirus prevalence in the oral cavity

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

of men who have sex with men: a study of its first from Beirut, Lebanon.: Sex Health. 2016 Jun 23; Authors: Maatouk I, Abdo K Abstract Background: Human papillomavirus (HPV) infection is the most common sexually transmissible viral infection worldwide. HPV is highly prevalent in sexually active men who have sex with men (MSM). The main objective of this study is to assess HPV prevalence in the oral cavity of MSM from Beirut, Lebanon. Methods: From November 2015 to January 2016, 42 MSM were recruited using respondent-driven sampling and provided oral samples for HPV DNA and for li... περισσότερα »

Polymorphisms in HLA-DQ genes, together with age, sex, and Helicobacter pylori infection, as potential biomarkers for the early diagnosis of gastric cancer

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Polymorphisms in HLA-DQ genes, together with age, sex, and Helicobacter pylori infection, as potential biomarkers for the early diagnosis of gastric cancer: Abstract Background Polymorphisms in inflammation-related genes are factors associated with the development of gastroduodenal diseases in *Helicobacter pylori-*infected individuals. Materials and Methods We aimed to analyze polymorphisms in *HLA-DQ*, together with other host and *H. pylori* variables as risk factors for precancerous and cancerous gastric lesions. 1052 individuals were studied, including nonatrophic gastritis ... περισσότερα »

Results using the OPAL strategy in Mandarin speaking cochlear implant recipients

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Results using the OPAL strategy in Mandarin speaking cochlear implant recipients: 10.1080/14992027.2016.1190872 Andrew E. Vandali Abstract *Objective*: To evaluate the effectiveness of an experimental pitch-coding strategy for improving recognition of Mandarin lexical tone in cochlear implant (CI) recipients. *Design*: Adult CI recipients were tested on recognition of Mandarin tones in quiet and speech-shaped noise at a signal-to-noise ratio of +10 dB; Mandarin sentence speech-reception threshold (SRT) in speech-shaped noise; and pitch discrimination of synthetic complex-h... περισσότερα »

Hearing thresholds, tinnitus, and headphone listening habits in nine-year-old children

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Hearing thresholds, tinnitus, and headphone listening habits in nine-year-old children: 10.1080/14992027.2016.1190871 Sara Båsjö ABSTRACT *Objective*: Investigate hearing function and headphone listening habits in nine-year-old Swedish children. *Design*: A cross-sectional study was conducted and included otoscopy, tympanometry, pure-tone audiometry, and spontaneous otoacoustic emissions (SOAE). A questionnaire was used to evaluate headphone listening habits, tinnitus, and hyperacusis.*Study sample*: A total of 415 children aged nine years. *Results*: The prevalence of a h... περισσότερα »

Sudden sensorineural hearing loss with positional vertigo: Initial findings of positional nystagmus and hearing outcomes

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Sudden sensorineural hearing loss with positional vertigo: Initial findings of positional nystagmus and hearing outcomes: 10.1080/14992027.2016.1194532 Chang-Hee Kim Abstract *Objectives*: To investigate the initial findings of positional nystagmus in patients with sudden sensorineural hearing loss (SSNHL) and positional vertigo, and to compare hearing improvement among patients with different types of positional nystagmus. *Design*: The characteristics of positional nystagmus upon initial examination were analysed, and the initial mean pure-tone audiometry (PTA) threshold... περισσότερα »

Audiology patient fall statistics and risk factors compared to non-audiology patients

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Audiology patient fall statistics and risk factors compared to non-audiology patients: 10.1080/14992027.2016.1193235 Robin E. Criter Abstract *Objective*: To compare fall statistics (e.g. incidence, prevalence), fall risks, and characteristics of patients who seek hearing healthcare from an audiologist to individuals who have not sought such services. *Design*: Case-control study. *Study sample*: Two groups of community-dwelling older adult patients: 25 audiology patients aged 60 years or older (*M* age: 69.2 years, *SD*: 4.5, range: 61–77) and a control group (gender- and ... περισσότερα »

On Peer Review

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

On Peer Review: Purpose This letter briefly reviews ideas about the purpose and benefits of peer review and reaches some idealistic conclusions about the process. Method The author uses both literature review and meditation born of long experience. Results From a cynical perspective, peer review constitutes an adversarial process featuring domination of the weak by the strong and exploitation of authors and reviewers by editors and publishers, resulting in suppression of new ideas, delayed publication of important research, and bad feelings ranging from confusion to fury. More opti... περισσότερα »

Meniere's Disease

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

University Of Colorado Menieres: As anyone who has ever experienced problems with hearing loss can attest, it can be one of the most frustrating and debilitating conditions a person can experience. As a result, more and more research has been conducted in recent years to find out not only the causes of hearing issues, but how to prevent and hopefully have a cure for those who deal with these conditions. Some of the most promising research has been conducted at the University of Colorado, where researchers believe they have found not only what causes Meniere's disease, but also how t... περισσότερα »

Trunk stability adaptations

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 13 δευτερόλεπτα

Sports-related testing protocols are required to reveal trunk stability adaptations in high-level athletes via Gait & Posture Publication date: Available online 23 June 2016 *Source:*Gait & Posture Author(s): David Barbado, Luis C. Barbado, Jose L.L. Elvira, Jaap H.van Dieën, Francisco J. Vera-Garcia Trunk/core stability is considered a key component of training programs, because it could contribute to prevention of low-back and lower-limb injuries and to sports performance. Based on the specificity principle, sports-related trunk stability tests would be required in elite sports pe... περισσότερα »

A descriptive comparison of approaches to paediatric tube weaning across five countries

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

10.1080/17549507.2016.1193898 Alison Y. GArdiner from Speech via a.lsfakia on Inoreader http://ift.tt/28Q37Wf via IFTTT περισσότερα »

Sleep Stage Coordination of Respiration and Swallowing: A Preliminary Study

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

Development of a Multimedia Dysphagia Assessment Learning System Using Responsive Web Design: From e-Learning to m-Learning.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

Polymorphisms in HLA-DQ genes, together with age, sex, and Helicobacter pylori infection, as potential biomarkers for the early diagnosis of gastric cancer

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

Abstract Background Polymorphisms in inflammation-related genes are factors associated with the development of gastroduodenal diseases in *Helicobacter pylori-*infected individuals. Materials and Methods We aimed to analyze polymorphisms in *HLA-DQ*, together with other host and *H. pylori* variables as risk factors for precancerous and cancerous gastric lesions. 1052 individuals were studied, including nonatrophic gastritis (NAG), intestinal metaplasia (IM), gastric cancer (GC) or duodenal ulcer (DU) patients, and healthy volunteers. Results Patients with alleles DQA*01:01 (OR... περισσότερα »

Achalasia: From Bench to Peroral Endoscopic Myotomy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

Nonthyroid Metastasis to the Thyroid Gland: Case Series and Review with Observations by Primary Pathology.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

Clinical Reasoning: An 11-year-old boy with language disorder and epilepsy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Clinical Reasoning: An 11-year-old boy with language disorder and epilepsy.* Neurology. 2016 Feb 2;86(5):e48-53 Authors: Dong L, Zhou XQ PMID: 26833943 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1PgEvCh via IFTTT περισσότερα »

Gastroesophageal Reflux Disease and Sleeve Gastrectomy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

Rare presentation of orbital plasmablastic lymphoma with oral cavity involvement in an HIV-negative patient.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

A multisensor approach to improve manometric analysis of the upper esophageal sphincter.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

A Novel Sleep Positioning Device Reduces Gastroesophageal Reflux: A Randomized Controlled Trial.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

Changes in Health-Related Quality of Life After Gastric Bypass in Patients With and Without Obesity-Related Disease.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 18 δευτερόλεπτα

Stapedotomy vs Cochlear Implantation for Advanced Otosclerosis: Systematic Review and Meta-analysis.

otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 31 δευτερόλεπτα

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Stapedotomy vs Cochlear Implantation for Advanced Otosclerosis: Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2016 Jun 21; Authors: Abdurehim Y, Lehmann A, Zeitouni AG Abstract OBJECTIVES: To compare the hearing outcomes of stapedotomy vs cochlear implantation in patients with advanced otosclerosis. DATA SOURCES: PubMed, EMBASE, and The Cochrane Library were searched for the terms […] περισσότερα »

How the sounds you hear affect the taste of your beer – Washington Post

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 36 δευτερόλεπτα

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Washington Post How the sounds you hear affect the taste of your beer Washington Post Not with false sweeteners that leave behind an acidic taste on a tongue and potentially cause cancer — just by using less sugar and adding the right music. "Perhaps we could diminish the sweetness of food without affecting the pleasure […] περισσότερα »

Feasibility and Limitations of Vaccine Two-Dimensional Barcoding Using Mobile Devices

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/28Yyz3B via IFTTT περισσότερα »

IJMS, Vol. 17, Pages 994: Conductive Hybrid Crystal Composed from Polyoxomolybdate and Deprotonatable Ionic-Liquid Surfactant

A polyoxomolybdate inorganic-organic hybrid crystal was synthesized with deprotonatable ionic-liquid surfactant. 1-dodecylimidazolium cation was employed for its synthesis. The hybrid crystal contained δ-type octamolybdate (Mo8) isomer, and possessed alternate stacking of Mo8 monolayers and interdigitated surfactant bilayers. The crystal structure was compared with polyoxomolybdate hybrid crystals comprising 1-dodecyl-3-methylimidazolium surfactant, which preferred β-type Mo8 isomer. The […] περισσότερα »

New knowledge about DNA repair mechanism could lead to cancer inhibitors

Professor Anja Groth and her research team at the University of Copenhagen are concerned with understanding the basic molecular mechanisms responsible for the development and maintenance of the more than 200 specific cell types in our body. Now, new… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/28YziSq via IFTTT περισσότερα »

Medically Assisted Insemination

The post Medically Assisted Insemination appeared first on Welcome to Avens. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/28S7cMw via IFTTT περισσότερα »

Taking the plunge! – Oxfordshire Guardian

Oxfordshire Guardian Taking the plunge! Oxfordshire Guardian The cause is close to both their hearts after Mr Belton was diagnosed with cancer of the tonsil, throat, back of the tongue and two lymph nodes in the neck. He underwent treatment at the Churchill and has since been given the all-clear. Mr Belton … from #AlexandrosSfakianakis […] περισσότερα »

The Dynamical Behaviors in a Stochastic SIS Epidemic Model with Nonlinear Incidence

A stochastic SIS-type epidemic model with general nonlinear incidence and disease-induced mortality is investigated. It is proved that the dynamical behaviors of the model are determined by a certain threshold value . That is, when and together with an additional condition, the disease is extinct with probability one, and when , the disease is permanent […] περισσότερα »

Detecting Variation Trends of Temperature and Precipitation for the Dadu River Basin, China

This study analyzes the variation trends of temperature and precipitation in the Dadu River Basin of China based on observed records from fourteen meteorological stations. The magnitude of trends was estimated using Sen's linear method while its statistical significance was evaluated using Mann-Kendall's test. The results of analysis depict increase change from northwest to southeast […] περισσότερα »

Scalability Optimization of Seamless Positioning Service

Recently positioning services are getting more attention not only within research community but also from service providers. From the service providers point of view positioning service that will be able to work seamlessly in all environments, for example, indoor, dense urban, and rural, has a huge potential to open new markets. However, such system does […] περισσότερα »

Simultaneous Chronic Invasive Fungal Infection and Tracheal Fungus Ball Mimicking Cancer in an Immunocompetent Patient

Fungal infections of the lung are uncommon and mainly affect people with immune deficiency. There are crucial problems in the diagnosis and treatment of this condition. Invasive pulmonary aspergillosis and candidiasis are the most common opportunistic fungal infections. Aspergillus species (spp.) are saprophytes molds that exist in nature as spores and rarely cause disease in […] περισσότερα »

Sleep Stage Coordination of Respiration and Swallowing: A Preliminary Study

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

Polymorphisms in HLA-DQ genes, together with age, sex, and Helicobacter pylori infection, as potential biomarkers for the early diagnosis of gastric cancer

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

A descriptive comparison of approaches to paediatric tube weaning across five countries

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

10.1080/17549507.2016.1193898 Alison Y. GArdiner from #ENT via xlomafota13 on Inoreader http://ift.tt/28Q37Wf via IFTTT περισσότερα »

A descriptive comparison of approaches to paediatric tube weaning across five countries

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 36 δευτερόλεπτα

10.1080/17549507.2016.1193898 Alison Y. GArdiner from Speech via xlomafota13 on Inoreader http://ift.tt/28Q37Wf περισσότερα »

Evolving National Strategy Driving Nursing Informatics in New Zealand.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 36 δευτερόλεπτα

*Evolving National Strategy Driving Nursing Informatics in New Zealand.* Stud Health Technol Inform. 2016;225:183-187 Authors: Honey M, Westbrooke L Abstract An update to the New Zealand Health Strategy identifying direction and priorities for health services is underway. Three specific areas have implications for nursing informatics and link to education and practice: best use of technology and information, fostering and spreading innovation and quality improvements, and building leaders and capability for the future. An emphasis on prevention and wellness means nursing needs to ... περισσότερα »

Chronic Cough and Gastroesophageal Reflux Disease.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 36 δευτερόλεπτα

*Chronic Cough and Gastroesophageal Reflux Disease.* Gastroenterol Hepatol (N Y). 2016 Jan;12(1):64-6 Authors: Francis DO PMID: 27330507 [PubMed] from Speech via xlomafota13 on Inoreader http://ift.tt/28RURqy περισσότερα »

Laryngeal leishmaniasis in a patient taking inhaled corticosteroids.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 36 δευτερόλεπτα

*Laryngeal leishmaniasis in a patient taking inhaled corticosteroids.* BMJ Case Rep. 2016;2016 Authors: Roberts RM, Mukherjee J, Phillips D Abstract We present a case of a man in his late 60s, who had spent 3-4 months of the year in rural Spain, presenting with intermittent hoarseness of voice. He had a background of asthma and bronchiectasis, and was taking inhaled corticosteroids. His dysphonia was initially managed as bronchiectasis with little improvement. Bronchoscopy revealed a cystic lesion on his left vocal fold, and tissue biopsy revealed Leishmania amastigotes. This conf... περισσότερα »

Physiology

Alexandros G. SfakianakisστοEvolutionary PhysiologyΠριν από 45 δευτερόλεπτα

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Journal of Neurophysiology

Alexandros G. SfakianakisστοEvolutionary PhysiologyΠριν από 45 δευτερόλεπτα

*Your subscribed feeds are not being updated automatically because this setting is turned off.* Turn on automatic feed updates *You've successfully subscribed to this feed!* Updated content can be viewed in Internet Explorer and other programs that use the Common Feed List. View my feeds *You've successfully subscribed to this feed!* Journal of Neurophysiology: Ahead of Print RSS feed *You are viewing a feed that contains frequently updated content.* When you subscribe to a feed, it is added to the Common Feed List. Updated information from the feed is automatically downloaded to your ... περισσότερα »

Surg Radiol Anat

Alexandros G. SfakianakisστοHead and Neck DiseasesΠριν από 48 δευτερόλεπτα

*Your subscribed feeds are not being updated automatically because this setting is turned off.* Turn on automatic feed updates *You've successfully subscribed to this feed!* Updated content can be viewed in Internet Explorer and other programs that use the Common Feed List. View my feeds *You've successfully subscribed to this feed!* pubmed: "surg radiol anat"[j... *You are viewing a feed that contains frequently updated content.* When you subscribe to a feed, it is added to the Common Feed List. Updated information from the feed is automatically downloaded to your computer and can be... περισσότερα »

Rambam Maimonides Med J

Alexandros G. SfakianakisστοHead and Neck DiseasesΠριν από 48 δευτερόλεπτα

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The Annals of otology, rhinology, and laryngology

Alexandros G. SfakianakisστοHead and Neck DiseasesΠριν από 48 δευτερόλεπτα

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HNO

Alexandros G. SfakianakisστοHead and Neck DiseasesΠριν από 48 δευτερόλεπτα

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Regional anesthesia and pain medicine

Alexandros G. SfakianakisστοHead and Neck DiseasesΠριν από 52 δευτερόλεπτα

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American Journal of Clinical and Experimental Immunology

Alexandros G. SfakianakisστοHead and Neck DiseasesΠριν από 52 δευτερόλεπτα

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American Goiter Association

Alexandros G. SfakianakisστοHead and Neck DiseasesΠριν από 52 δευτερόλεπτα

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Inflammation

Alexandros G. SfakianakisστοHead and Neck DiseasesΠριν από 52 δευτερόλεπτα

*Your subscribed feeds are not being updated automatically because this setting is turned off.* Turn on automatic feed updates *You've successfully subscribed to this feed!* Updated content can be viewed in Internet Explorer and other programs that use the Common Feed List. View my feeds *You've successfully subscribed to this feed!* Latest Results for Inflammation *You are viewing a feed that contains frequently updated content.* When you subscribe to a feed, it is added to the Common Feed List. Updated information from the feed is automatically downloaded to your computer and can be... περισσότερα »

Stapedotomy vs Cochlear Implantation for Advanced Otosclerosis: Systematic Review and Meta-analysis.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

*Stapedotomy vs Cochlear Implantation for Advanced Otosclerosis: Systematic Review and Meta-analysis.* Otolaryngol Head Neck Surg. 2016 Jun 21; Authors: Abdurehim Y, Lehmann A, Zeitouni AG Abstract OBJECTIVES: To compare the hearing outcomes of stapedotomy vs cochlear implantation in patients with advanced otosclerosis. DATA SOURCES: PubMed, EMBASE, and The Cochrane Library were searched for the terms otosclerosis, stapedotomy, and cochlear implantation and their synonyms with no language restrictions up to March 10, 2015. METHODS: Studies comparing the hearing outcomes of stapedot... περισσότερα »

Clinical Reasoning: An 11-year-old boy with language disorder and epilepsy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Clinical Reasoning: An 11-year-old boy with language disorder and epilepsy.* Neurology. 2016 Feb 2;86(5):e48-53 Authors: Dong L, Zhou XQ PMID: 26833943 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1PgEvCh via IFTTT περισσότερα »

Gastroesophageal Reflux Disease and Sleeve Gastrectomy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

Left Superior Temporal Gyrus Is Coupled to Attended Speech in a Cocktail-Party Auditory Scene.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Left Superior Temporal Gyrus Is Coupled to Attended Speech in a Cocktail-Party Auditory Scene.* J Neurosci. 2016 Feb 3;36(5):1596-606 Authors: Vander Ghinst M, Bourguignon M, Op de Beeck M, Wens V, Marty B, Hassid S, Choufani G, Jousmäki V, Hari R, Van Bogaert P, Goldman S, De Tiège X Abstract UNLABELLED: Using a continuous listening task, we evaluated the coupling between the listener's cortical activity and the temporal envelopes of different sounds in a multitalker auditory scene using magnetoencephalography ... περισσότερα »

Rare presentation of orbital plasmablastic lymphoma with oral cavity involvement in an HIV-negative patient.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

Effects of cholinesterase inhibitor on brain activation in Alzheimer's patients measured with functional near-infrared spectroscopy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

[image: http:--production.springer.de-OnlineReso] Related Articles *Effects of cholinesterase inhibitor on brain activation in Alzheimer's patients measured with functional near-infrared spectroscopy.* Psychopharmacology (Berl). 2015 Dec;232(23):4383-91 Authors: Metzger FG, Ehlis AC, Haeussinger FB, Fallgatter AJ, Hagen K Abstract RATIONALE: Neurobiological effects of neuropsychiatric medication can contribute to the understanding of mechanisms of action and to the evaluation of target medication effects. Cholinesterase inhibitors (ChEI) have been used in patients with Alzheimer's... περισσότερα »

Dysphagia aortica: a rare cause of dysphagia.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

Interaction in planning movement direction for articulatory gestures and manual actions.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

[image: http:--production.springer.de-OnlineReso] Related Articles *Interaction in planning movement direction for articulatory gestures and manual actions.* Exp Brain Res. 2015 Oct;233(10):2951-9 Authors: Vainio L, Tiainen M, Tiippana K, Komeilipoor N, Vainio M Abstract Some theories concerning speech mechanisms assume that overlapping representations are involved in programming certain articulatory gestures and hand actions. The present study investigated whether planning of movement direction for articulatory gestures and manual actions could interact. The participants were pr... περισσότερα »

Tongue thickness evaluation using ultrasonography can predict swallowing function in amyotrophic lateral sclerosis patients.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

The Effectiveness of Two Grammar Treatment Procedures for Children With SLI: A Randomized Clinical Trial.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

[image: http:--pubs.asha.org-images-b_pubmed_ful] Related Articles *The Effectiveness of Two Grammar Treatment Procedures for Children With SLI: A Randomized Clinical Trial.* Lang Speech Hear Serv Sch. 2015 Oct;46(4):312-24 Authors: Smith-Lock KM, Leitão S, Prior P, Nickels L Abstract PURPOSE: This study compared the effectiveness of two grammar treatment procedures for children with specific language impairment. METHOD: A double-blind superiority trial with cluster randomization was used to compare a cueing procedure, designed to elicit a correct production following an initial e... περισσότερα »

A Novel Sleep Positioning Device Reduces Gastroesophageal Reflux: A Randomized Controlled Trial.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

The Ability of Children With Language Impairment to Dissemble Emotions in Hypothetical Scenarios and Natural Situations.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

[image: http:--pubs.asha.org-images-b_pubmed_ful] Related Articles *The Ability of Children With Language Impairment to Dissemble Emotions in Hypothetical Scenarios and Natural Situations.* Lang Speech Hear Serv Sch. 2015 Oct;46(4):325-36 Authors: Brinton B, Fujiki M, Hurst NQ, Jones ER, Spackman MP Abstract PURPOSE: This study examined the ability of children with language impairment (LI) to dissemble (hide) emotional reactions when socially appropriate to do so. METHOD: Twenty-two children with LI and their typically developing peers (7;1-10;11 [years;months]) participated in tw... περισσότερα »

Changes in Health-Related Quality of Life After Gastric Bypass in Patients With and Without Obesity-Related Disease.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 52 δευτερόλεπτα

The 'Melanoma-enriched' microRNA miR-4731-5p acts as a tumour suppressor.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*The 'Melanoma-enriched' microRNA miR-4731-5p acts as a tumour suppressor.* Oncotarget. 2016 Jun 16; Authors: Stark MS, Tom LN, Boyle GM, Bonazzi VF, Soyer HP, Herington AC, Pollock PM, Hayward NK Abstract We previously identified miR-4731-5p (miR-4731) as a melanoma-enriched microRNA following comparison of melanoma with other cell lines from solid malignancies. Additionally, miR-4731 has been found in serum from melanoma patients and expressed less abundantly in metastatic melanoma tissues from stage IV patients relative to stage III patients. As miR-4731 has no known function,... περισσότερα »

Simple chronic colitis model using hypopigmented mice with a Hermansky-Pudlak syndrome 5 gene mutation.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Simple chronic colitis model using hypopigmented mice with a Hermansky-Pudlak syndrome 5 gene mutation.* Pigment Cell Melanoma Res. 2016 Jun 22; Authors: Itoh Y, Nagaoka Y, Katakura Y, Kawahara H, Takemori H Abstract Pigmentation in mammals is important for protection of skin and eyes from ultraviolet radiation. Dysregulation of pigmentation is often associated with other conditions that are not directly linked to pigmentation. Here, we isolated spontaneously occurring hypopigmented mice that occasionally experienced severe diarrhea during lactation. Treatment of these mice with ... περισσότερα »

Residual FDG-PET metabolic activity in metastatic melanoma patients with prolonged response to anti-PD-1 therapy.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Residual FDG-PET metabolic activity in metastatic melanoma patients with prolonged response to anti-PD-1 therapy.* Pigment Cell Melanoma Res. 2016 Jun 22; Authors: Kong BY, Menzies AM, Saunders CA, Liniker E, Ramanujam S, Guminski A, Kefford RF, Long GV, Carlino MS Abstract FDG-PET scans were performed on twenty seven patients with unresectable stage IIIC or IV melanoma after prolonged treatment with anti-PD-1 antibodies to examine the hypothesis that patients with prolonged response to treatment may have metabolically inactive lesions by FDG-PET. Scans were performed at a media... περισσότερα »

Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.* EBioMedicine. 2016 Jun 16; Authors: Benamar M, Guessous F, Du K, Corbett P, Obeid J, Gioeli D, Slingluff CL, Abbas T Abstract The cullin-based CRL4-CDT2 ubiquitin ligase is emerging as a master regulator of cell proliferation. CRL4-CDT2 prevents re-initiation of DNA replication during the same cell cycle "rereplication" through targeted degradation of CDT1, SET8 and p21 during S-phase of the cell cycle. We show that CDT2 is overexpressed in ... περισσότερα »

The 'Melanoma-enriched' microRNA miR-4731-5p acts as a tumour suppressor.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

Combining immune checkpoint inhibitors for advanced melanoma: the key to optimizing treatment outcomes?

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Combining immune checkpoint inhibitors for advanced melanoma: the key to optimizing treatment outcomes?* J Comp Eff Res. 2016 Jun 22; Authors: Freeston S PMID: 27331424 [PubMed - as supplied by publisher] from Melanoma via xlomafota13 on Inoreader http://ift.tt/28P1BEp περισσότερα »

Malignant melanoma arising in a mature teratoma: A case report with review of the recent literature.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Malignant melanoma arising in a mature teratoma: A case report with review of the recent literature.* Gynecol Oncol Rep. 2016 Apr;16:47-50 Authors: Brudie LA, Khan F, Radi MJ, Yates MM, Ahmad S Abstract Mature cystic teratomas constitute 10-20% of all ovarian neoplasms. Malignant transformation is very rare occurring in only 0.1-2% of mature teratoma cases. Malignant melanoma is among the least common transformations. Herein, we describe a case of young woman initially undergoing evaluation for infertility who was found to have malignant melanoma arising in a mature dermoid cyst... περισσότερα »

Combined immunotherapy and radiation for treatment of mucosal melanomas of the lower genital tract.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Combined immunotherapy and radiation for treatment of mucosal melanomas of the lower genital tract.* Gynecol Oncol Rep. 2016 Apr;16:42-6 Authors: Schiavone MB, Broach V, Shoushtari AN, Carvajal RD, Alektiar K, Kollmeier MA, Abu-Rustum NR, Leitao MM Abstract OBJECTIVE: To report our experience using ipilimumab, a monoclonal antibody targeting CTLA-4, combined with radiation therapy in women diagnosed with mucosal melanoma of the lower genital tract. METHODS: We retrospectively identified all patients who received ipilimumab with concurrent radiation treatment of mucosal melanoma o... περισσότερα »

Melanoma Metastasizing to the Small Intestine: A Case Report Illustrating Symptomatic and Asymptomatic Involvement.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Melanoma Metastasizing to the Small Intestine: A Case Report Illustrating Symptomatic and Asymptomatic Involvement.* Cureus. 2016;8(5):e608 Authors: Asad-Ur-Rahman F, Abbass A, Majeed U, Navaneethan U Abstract Symptomatic gastrointestinal (GI) involvement of melanoma is rare, however, it is a frequent autopsy finding in patients with primary cutaneous melanoma. We present a case of metastatic cutaneous melanoma with initial asymptomatic jejunal involvement as found on a positron emission tomography (PET) scan, with subsequent duodenal perforation. A 69-year-old man presented to ... περισσότερα »

Phenotypic and functional testing of circulating regulatory T cells in advanced melanoma patients treated with neoadjuvant ipilimumab.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Phenotypic and functional testing of circulating regulatory T cells in advanced melanoma patients treated with neoadjuvant ipilimumab.* J Immunother Cancer. 2016;4:38 Authors: Retseck J, VanderWeele R, Lin HM, Lin Y, Butterfield LH, Tarhini AA Abstract BACKGROUND: We have previously investigated neoadjuvant ipilimumab (ipi) for patients with locally/regionally advanced melanoma. That initial assessment of peripheral blood mononuclear cells (PBMC) showed a significant increase in shared tumor associated antigen specific CD4(+) and CD8(+) T cell activation. We also observed a trans... περισσότερα »

Single dose denileukin diftitox does not enhance vaccine-induced T cell responses or effectively deplete Tregs in advanced melanoma: immune monitoring and clinical results of a randomized phase II trial.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Single dose denileukin diftitox does not enhance vaccine-induced T cell responses or effectively deplete Tregs in advanced melanoma: immune monitoring and clinical results of a randomized phase II trial.* J Immunother Cancer. 2016;4:35 Authors: Luke JJ, Zha Y, Matijevich K, Gajewski TF Abstract BACKGROUND: Depletion of CD25(+) Tregs improves anti-tumor immunity in preclinical models. Denileukin diftitox is a recombinant fusion protein of human IL-2 and diptheria toxin fragment that also can kill CD25(+) T cells. Prior clinical trials of denileukin diftitox suggested reduction of ... περισσότερα »

Clinical significance of serum laminin and type-IV collagen levels in cutaneous melanoma patients.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Clinical significance of serum laminin and type-IV collagen levels in cutaneous melanoma patients.* Mol Clin Oncol. 2016 Jul;5(1):195-200 Authors: Tas F, Bilgin E, Karabulut S, Duranyildiz D Abstract Laminin and type-IV collagen constitute a significant portion of the extracellular matrix. The objective of the present study was to evaluate whether the serum concentrations of laminin and type-IV collagen may serve as biomarkers for cutaneous melanoma. Sixty pathologically confirmed melanoma patients were enrolled in the study. Serum laminin and type-IV collagen levels were assess... περισσότερα »

In vivo enhancement of the MAGE-specific cellular immune response by a recombinant MAGE1-MAGE3-TBHSP70 tumor vaccine.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*In vivo enhancement of the MAGE-specific cellular immune response by a recombinant MAGE1-MAGE3-TBHSP70 tumor vaccine.* Cancer Cell Int. 2016;16:45 Authors: Junwei W, Xiumin Z, Jing Y, Shoujing Y, Zengshan L Abstract BACKGROUND: Since cytotoxic T cell (CTL) response is the major cellular type in attacking tumor cells, most immunotherapy targets to manipulate the CTL response. Immunotherapies targeting melanoma-specific antigens (MAGEs), a group of tumor-specific shared antigen, have shown to be promising. Our previous study has shown that MAGE1/TBHSP70 and MAGE3/TBHSP70 could indu... περισσότερα »

Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nsp4 Cleaves VISA to Impair Antiviral Responses Mediated by RIG-I-like Receptors.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nsp4 Cleaves VISA to Impair Antiviral Responses Mediated by RIG-I-like Receptors.* Sci Rep. 2016;6:28497 Authors: Huang C, Du Y, Yu Z, Zhang Q, Liu Y, Tang J, Shi J, Feng WH Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most significant etiological agents in the swine industry worldwide. It has been reported that PRRSV infection can modulate host immune responses, and innate immune evasion is thought to play a vital role in PRRSV pathogenesis. In this study, we demonstrated... περισσότερα »

Discovery of 1-(1H-Pyrazolo[4,3-c]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Discovery of 1-(1H-Pyrazolo[4,3-c]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers.* J Med Chem. 2016 Jun 22; Authors: Lim J, Kelley EH, Methot JL, Zhou H, Petrocchi A, Chen H, Hill SE, Hinton MC, Hruza A, Jung JO, Maclean JK, Mansueto M, Naumov GN, Philippar U, Raut S, Spacciapoli P, Sun D, Siliphaivanh P Abstract The ERK/MAPK pathway plays a central role in the regulation of critical cellular processes and is activated in more than 30% of human cancers. Specific BRAF and MEK inhibitors have shown clinical efficacy in patie... περισσότερα »

Integumentary Disorders Including Cutaneous Neoplasia in Older Horses.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Integumentary Disorders Including Cutaneous Neoplasia in Older Horses.* Vet Clin North Am Equine Pract. 2016 Jun 18; Authors: Knottenbelt DC Abstract Few skin diseases specifically or exclusively affect older horses and donkeys. Hypertrichosis (hirsutism) associated with pituitary pars intermedia dysfunction is probably the most recognized and best understood exception and is the most common age-related skin condition in equids. Many other conditions are known to be more serious in older horses. Horses affected with immune-compromising conditions can be more severely affected by... περισσότερα »

Inequalities in cancer incidence and mortality across medium to highly developed countries in the twenty-first century.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Inequalities in cancer incidence and mortality across medium to highly developed countries in the twenty-first century.* Cancer Causes Control. 2016 Jun 21; Authors: Arnold M, Rentería E, Conway DI, Bray F, Van Ourti T, Soerjomataram I Abstract PURPOSE: Inequalities in the burden of cancer have been well documented, and a variety of measures exist to analyse disease disparities. While previous studies have focused on inequalities within countries, the aim of the present study was to quantify existing inequalities in cancer incidence and mortality between countries. METHODS: Data... περισσότερα »

Absent in melanoma 2 proteins in the development of cancer.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Absent in melanoma 2 proteins in the development of cancer.* Cell Mol Life Sci. 2016 Jun 21; Authors: Choubey D Abstract Recent studies utilizing chemical-induced colitis-associated and sporadic colon cancer in mouse models indicated a protective role for absent in melanoma 2 (Aim2) in colon epithelial cells. Accordingly, mutations in the human AIM2 gene have been found in colorectal cancer (CRC), and reduced expression of AIM2 in CRC is associated with its progression. Furthermore, the overexpression of AIM2 protein in human cancer cell lines inhibits cell proliferation. Interf... περισσότερα »

Immunosuppressive therapy in the posttransplant period and skin cancer.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Immunosuppressive therapy in the posttransplant period and skin cancer.* Dermatol Ther. 2016 Jun 21; Authors: Krásová M, Sečníková Z, Göpfertová D, Hercogová J, Viklický O, Jůzlová K, Jiráková A, Šmerhovský Z Abstract AIMS: To determine the incidence of malignancies in renal transplant recipients (RTRs) and to analyze the association between the risk of skin cancer and immunosuppressive regiments used in the posttransplant period. MATERIALS AND METHODS: A cohort study was performed on 797 RTRs. Standardized morbidity ratio (SMR) was calculated for the most common types of cancer ... περισσότερα »

Antimelanoma effect of Salmonella Typhimurium integration host factor mutant in murine model.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*Antimelanoma effect of Salmonella Typhimurium integration host factor mutant in murine model.* Future Oncol. 2016 Jun 22; Authors: Hirsch Werle C, Damiani I, Paier Milanez G, Farias AS, Cintra Gomes Marcondes MC, Fabricio Culler H, Palma Sircili M, Leite B, Brocchi M Abstract AIM: This study aimed to evaluate an attenuated Salmonella ihfA-null mutant strain as therapeutic agent to control tumor growth. MATERIALS & METHODS: After bacterial toxicity evaluation, C57BL/6JUnib mice were inoculated with B16F10 cells and treated with two Salmonella strains (LGBM 1.1 and LGBM 1.41). RESU... περισσότερα »

miR-214 and miR-148b targeting inhibits dissemination of melanoma and breast cancer.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

*miR-214 and miR-148b targeting inhibits dissemination of melanoma and breast cancer.* Cancer Res. 2016 Jun 21; Authors: Orso F, Quirico L, Virga F, Penna E, Dettori D, Cimino D, Coppo R, Grassi E, Elia AR, Brusa D, Deaglio S, Brizzi MF, Stadler MB, Provero P, Caselle M, Taverna D Abstract miR-214 and miR-148b have been proposed to antagonize the effects of each other in enabling or blocking metastasis, respectively. In this study, we provide evidence deepening their role and interrelationship in the process of metastatic dissemination. Depleting miR-214 or elevating miR-148b bl... περισσότερα »

Non-primary breast malignancies: a single institution's experience of a diagnostic challenge with important therapeutic consequences—a retrospective study

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα

AbstractBackground Breast cancer is a common malignancy, but metastases to the breast of extramammary malignancies are very rare. Treatment and prognosis are different. The aim of the study is to report the incidence of lymphomas and metastases to the breast of extramammary malignancies in our 30-year archive. Methods The pathology database of a single institute was reviewed for all breast neoplasms which were coded in our system as a *metastasis* in the period 1985–2014. Metastatic tumors from primary breast carcinoma were excluded. Results A total of 47 patients were included (7 ... περισσότερα »

Long-termin vivodegradation behavior and near-implant distribution of resorbed elements for magnesium alloys WZ21 and ZX50

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 59 δευτερόλεπτα

Publication date: Available online 22 June 2016 *Source:*Acta Biomaterialia Author(s): F. Amerstorfer, S.F. Fischerauer, L. Fischer, J. Eichler, J. Draxler, A. Zitek, M. Meischel, E. Martinelli, T. Kraus, S. Hann, S.E. Stanzl-Tschegg, P.J. Uggowitzer, J.F. Löffler, A.M. Weinberg, T. Prohaska We report on the long-term effects of degrading magnesium implants on bone tissue in a growing rat skeleton using continuous in vivo micro-Computed Tomography, histological staining and Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS). Two different magnesium alloys—one rapi... περισσότερα »

Supportive peri-implant therapy following anti-infective surgical peri-implantitis treatment: 5-year survival and success

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 59 δευτερόλεπτα

Abstract Objectives To evaluate clinical outcomes of supportive peri-implant therapy (SPIT) following surgical treatment of peri-implantitis. Materials and methods Twenty-four partially dentate patients with 36 dental implants diagnosed with peri-implantitis were treated by an anti-infective surgical protocol followed by regular supportive therapy. SPIT included removal of supra- and submucosal biofilm at the treated implants using titanium or carbon fibre curettes, or ultrasonic devices. In addition, professional prophylaxis (calculus/biofilm removal) at other implants/teeth and or... περισσότερα »

Bonding of Dental Ceramics to Titanium: Processing and Conditioning Aspects

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 59 δευτερόλεπτα

Abstract Difficulties related to titanium processing (casting) and the problematic titanium-ceramic bond have been limiting the latter's application in prosthetic dentistry for many years. Recent advances in subtractive and additive CAD/CAM technologies have provided alternative routes for titanium processing. The effect of a processing route on titanium surface characteristics and on the strength of its bond to porcelain need to be assessed, since most paths for enhancing porcelain bonding involve preparation of the titanium surface. Several approaches to bond enhancement have bee... περισσότερα »

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Πέμπτη 23 Ιουνίου 2016

OtoRhinoLaryngology & Medicine,New Articles,June 23rd,2016,afternoon

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