Analysis of risk factors for secondary new vertebral compression fracture following percutaneous vertebroplasty in patients with osteoporosis.

Analysis of risk factors for secondary new vertebral compression fracture following percutaneous vertebroplasty in patients with osteoporosis.

World Neurosurg. 2016 Dec 21;:

Authors: Bae JS, Park JH, Kim KJ, Kim HS, Jang IT

Abstract
OBJECTIVE: To analyze the risk factors for secondary new vertebral compression fracture(SNVCF) following percutaneous vertebroplasty in patients with osteoporosis.
MATERIALS AND METHODS: We investigated medical records and radiologic images from patients receiving percutaneous vertebroplasty(PV) due to osteoporotic vertebral compression fracture, between October 2009 and September 2014. We checked patients' age, past medical history and bone mineral content(BMC) using computed tomogram(CT). Further, procedure specific outcomes were assessed, including: the ratio of injected bone cement to vertebral body volume, bone cement distribution in the vertebral body (to identify the degree of consistency in bone cement injection), presence of bone cement leakage into the adjacent disc space, segmental kyphosis, and the time interval between first and second fracture events.
RESULTS: There were 293 patients(male: 60, female: 233) who were given PV, with a total of 336 affected levels . Of this cohort, 34(14.6%) patients suffered a SNVCF. We compared two patients groups; one group included those suffering a SNVCF, while the other did not. Significant differences were identified in BMC(p : 0.000) and bone cement distribution(p : 0.000). Further, those exhibiting bone cement leakage into disc space revealed a higher incidence of SNVCF than those without(p : 0.039).
CONCLUSION: Poor BMC can be one of the predictive factors of SNVCF. To prevent SNVCF, bone cement should be injected as evenly as possible into the vertebral body. And bone cement leakage into the disc space should be avoided.

PMID: 28012889 [PubMed - as supplied by publisher]

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