In search of a disease.
Surv Ophthalmol. 2016 Dec 21;:
Authors: Savino G, Campana A, Petrone G, Grimaldi G, Murchison AP
Abstract
A 10-year-old child presented with right eyelid swelling and a palpable orbital mass. Diagnostic evaluation with the aid of excisional biopsy revealed a pseudo- encapsulated mass associated with high levels of serum perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA). Family history of rheumatic diseases, response to treatment with corticosteroids and immunosuppressant drugs and clinical and histopathological features suggested an orbital autoimmune response in which p-ANCA antibodies were detected, and a diagnosis of probable IgG4-related disease was made.
PMID: 28012876 [PubMed - as supplied by publisher]
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