Cell-Intrinsic Defense at the Epithelial Border Wall: Salmonella Pays the Price

Publication date: 18 April 2017
Source:Immunity, Volume 46, Issue 4
Author(s): Sky W. Brubaker, Denise M. Monack
Within the gut, Salmonella-infected enterocytes are expelled into the lumen, limiting pathogen replication. In this issue of Immunity, Rauch et al. (2017) expand our understanding of this cell-intrinsic response by characterizing the genetic determinants that control the expulsion and death of epithelial cells.

Teaser

Within the gut, Salmonella-infected enterocytes are expelled into the lumen, limiting pathogen replication. In this issue of Immunity, Rauch et al. (2017) expand our understanding of this cell-intrinsic response by characterizing the genetic determinants that control the expulsion and death of epithelial cells.


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