Midkine and Melanoma Metastasis: A Malevolent Mix

Publication date: 7 August 2017
Source:Developmental Cell, Volume 42, Issue 3
Author(s): Sinem Karaman, Kari Alitalo
Using an in vivo reporter for lymphangiogenesis, a recent study in Nature from Olmeda et al. (2017) describes a new subset of melanomas that induce systemic pre-conditioning of distant organs for formation of tumor metastatic niches, and identifies the responsible factor as the pleiotropic cytokine midkine.

Teaser

Using an in vivo reporter for lymphangiogenesis, a recent study in Nature from Olmeda et al. (2017) describes a new subset of melanomas that induce systemic pre-conditioning of distant organs for formation of tumor metastatic niches and that show that the responsible factor is the pleiotropic cytokine midkine.


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