Effect of endotoxin and alum adjuvant vaccine on peanut allergy

Publication date: Available online 18 September 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Brandi T. Johnson-Weaver, Susan McRitchie, Kelly A. Mercier, Wimal Pathmasiri, Susan J. Sumner, Cliburn Chan, Dori Germolec, Michael Kulis, A. Wesley Burks, Herman F. Staats

Teaser

Environmental endotoxin and alum-adjuvanted vaccines did not influence peanut-allergy development in mice. Exposure to alum and CpG-adjuvanted vaccines indirectly reduced allergic disease severity. Fecal metabolites differentiated mice based on disease severity.


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